Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Plasmodium vivax | vivapain-2 | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin L | 0.0337 | 0.2216 | 0.2216 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0628 | 0.5467 | 0.5467 |
Echinococcus granulosus | cathepsin l1 | 0.0628 | 0.5467 | 0.5467 |
Plasmodium vivax | vivapain-3 | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1034 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0337 | 0.2216 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cysteine protease | 0.0337 | 0.2216 | 0.2216 |
Echinococcus multilocularis | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Plasmodium vivax | unspecified product | 0.0198 | 0.067 | 0.1225 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Plasmodium vivax | vivapain-2 | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin L | 0.0337 | 0.2216 | 0.2216 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0337 | 0.2216 | 0.2216 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1034 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0628 | 0.5467 | 0.5467 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0337 | 0.2216 | 0.2216 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0628 | 0.5467 | 0.5467 |
Onchocerca volvulus | Cathepsin F homolog | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0429 | 0.325 | 0.5946 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0198 | 0.067 | 0.067 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0628 | 0.5467 | 0.5467 |
Echinococcus multilocularis | cathepsin b | 0.1034 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.2216 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0198 | 0.067 | 0.067 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0198 | 0.067 | 0.067 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0415 | 0.3093 | 0.3093 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0628 | 0.5467 | 0.5467 |
Plasmodium vivax | vivapain-1 | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0198 | 0.067 | 0.067 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine protease, putative | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0415 | 0.3093 | 0.3093 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0429 | 0.325 | 0.325 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0628 | 0.5467 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0429 | 0.325 | 0.325 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0429 | 0.325 | 0.325 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.2216 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0429 | 0.325 | 0.5946 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0337 | 0.2216 | 0.2216 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Leishmania major | cysteine peptidase A (CPA) | 0.0628 | 0.5467 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0337 | 0.2216 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.0429 | 0.325 | 0.325 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0337 | 0.2216 | 0.4054 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Loa Loa (eye worm) | cathepsin B | 0.0415 | 0.3093 | 0.3093 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1034 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0628 | 0.5467 | 0.5467 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0198 | 0.067 | 0.067 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin b | 0.1034 | 1 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0337 | 0.2216 | 0.2216 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Plasmodium vivax | unspecified product | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0415 | 0.3093 | 0.2697 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Toxoplasma gondii | cathepsin B | 0.0415 | 0.3093 | 0.5658 |
Brugia malayi | cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0628 | 0.5467 | 1 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0429 | 0.325 | 0.5946 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0628 | 0.5467 | 0.5467 |
Schistosoma mansoni | cathepsin s | 0.0198 | 0.067 | 0.067 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0628 | 0.5467 | 0.5467 |
Echinococcus granulosus | cathepsin b | 0.1034 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1034 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Onchocerca volvulus | Cathepsin L homolog | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0429 | 0.325 | 0.5946 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0198 | 0.067 | 0.067 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0415 | 0.3093 | 0.5658 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.