Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0198 | 0.067 | 0.067 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0198 | 0.067 | 0.067 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0337 | 0.2216 | 0.2216 |
Plasmodium vivax | vivapain-1 | 0.0337 | 0.2216 | 0.4054 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0415 | 0.3093 | 0.3093 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.2216 |
Echinococcus multilocularis | cathepsin b | 0.1034 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0628 | 0.5467 | 0.5467 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0198 | 0.067 | 0.067 |
Loa Loa (eye worm) | fibroinase | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0198 | 0.067 | 0.067 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0429 | 0.325 | 0.5946 |
Onchocerca volvulus | Cathepsin F homolog | 0.0628 | 0.5467 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0628 | 0.5467 | 0.5467 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0628 | 0.5467 | 0.5467 |
Loa Loa (eye worm) | hypothetical protein | 0.1034 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0415 | 0.3093 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0337 | 0.2216 | 0.2216 |
Echinococcus granulosus | cathepsin L | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Plasmodium vivax | unspecified product | 0.0198 | 0.067 | 0.1225 |
Echinococcus granulosus | cysteine protease | 0.0337 | 0.2216 | 0.2216 |
Echinococcus multilocularis | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Plasmodium vivax | vivapain-2 | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0337 | 0.2216 | 0.4054 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1034 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Echinococcus multilocularis | cathepsin L | 0.0337 | 0.2216 | 0.2216 |
Plasmodium vivax | vivapain-2 | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0628 | 0.5467 | 0.5467 |
Plasmodium vivax | vivapain-3 | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0198 | 0.067 | 0.067 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0429 | 0.325 | 0.5946 |
Onchocerca volvulus | Cathepsin L homolog | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0415 | 0.3093 | 0.5658 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Echinococcus granulosus | cathepsin b | 0.1034 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.1034 | 1 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0429 | 0.325 | 0.5946 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0628 | 0.5467 | 0.5467 |
Schistosoma mansoni | cathepsin s | 0.0198 | 0.067 | 0.067 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0337 | 0.2216 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Brugia malayi | cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0628 | 0.5467 | 1 |
Toxoplasma gondii | cathepsin B | 0.0415 | 0.3093 | 0.5658 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0628 | 0.5467 | 1 |
Plasmodium vivax | unspecified product | 0.0337 | 0.2216 | 0.4054 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1034 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0415 | 0.3093 | 0.2697 |
Echinococcus granulosus | cathepsin b | 0.1034 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0198 | 0.067 | 0.067 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cysteine protease, putative | 0.0337 | 0.2216 | 0.2216 |
Loa Loa (eye worm) | cathepsin B | 0.0415 | 0.3093 | 0.3093 |
Loa Loa (eye worm) | cysteine protease | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0628 | 0.5467 | 0.5467 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0628 | 0.5467 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1034 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0337 | 0.2216 | 0.2216 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0628 | 0.5467 | 0.5467 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0628 | 0.5467 | 0.5467 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0628 | 0.5467 | 0.5467 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Onchocerca volvulus | 0.0628 | 0.5467 | 1 | |
Echinococcus granulosus | cathepsin l1 | 0.0429 | 0.325 | 0.325 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0628 | 0.5467 | 1 |
Leishmania major | cysteine peptidase A (CPA) | 0.0628 | 0.5467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.325 | 0.325 |
Brugia malayi | Cathepsin L-like precursor | 0.0429 | 0.325 | 0.325 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.2216 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0628 | 0.5467 | 0.5467 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0337 | 0.2216 | 0.2216 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0337 | 0.2216 | 0.2216 |
Onchocerca volvulus | 0.0429 | 0.325 | 0.5946 | |
Entamoeba histolytica | cysteine protease, putative | 0.0337 | 0.2216 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.0628 | 0.5467 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0628 | 0.5467 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0429 | 0.325 | 0.325 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0429 | 0.325 | 0.325 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0429 | 0.325 | 0.325 |
Loa Loa (eye worm) | hypothetical protein | 0.0198 | 0.067 | 0.067 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0415 | 0.3093 | 0.3093 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0628 | 0.5467 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0628 | 0.5467 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0337 | 0.2216 | 0.4054 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.