Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1529 | 0.741 | 0.741 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0296 | 0.0662 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Echinococcus granulosus | bile acid beta glucosidase | 0.1529 | 0.741 | 0.7227 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.154 | 0.7474 | 0.7295 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.2002 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1032 | 0.4691 | 0.4315 |
Schistosoma mansoni | alpha glucosidase | 0.0296 | 0.0662 | 0.0662 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.2002 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0744 | 0.3113 | 0.5745 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0908 | 0.4011 | 0.5 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.1075 | 0.4929 | 0.457 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.154 | 0.7474 | 0.7295 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.154 | 0.7474 | 0.7295 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.2002 | 1 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.2002 | 1 | 1 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0296 | 0.0662 | 0.5 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.2002 | 1 | 1 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.1529 | 0.741 | 0.7227 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0296 | 0.0662 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0296 | 0.0662 | 0.5 |
Trypanosoma brucei | glucosidase, putative | 0.0296 | 0.0662 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0296 | 0.0662 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.1377 | 0.658 | 0.658 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.154 | 0.7474 | 0.7295 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0296 | 0.0662 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.154 | 0.7474 | 0.7295 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.1529 | 0.741 | 0.7227 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.2002 | 1 | 1 |
Onchocerca volvulus | 0.0925 | 0.4108 | 0.1695 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0744 | 0.3113 | 0.5745 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0706 | 0.2906 | 0.5258 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.1075 | 0.4929 | 0.457 |
Schistosoma mansoni | alpha-glucosidase | 0.1377 | 0.658 | 0.658 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1075 | 0.4929 | 1 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1529 | 0.741 | 0.741 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.1529 | 0.741 | 0.7227 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (binding) | > 10 mM | Tested for binding activity against Selectin E of the compound; inactive | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.