Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.005 | 0.0368 | 0.0411 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus granulosus | geminin | 0.0548 | 0.5902 | 0.6646 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0019 | 0.0023 | 0.0074 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0037 | 0.0223 | 0.0248 |
Plasmodium falciparum | thioredoxin reductase | 0.005 | 0.0368 | 0.0471 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.0483 | 0.0623 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2634 | 0.3399 |
Plasmodium falciparum | zinc finger Ran-binding domain-containing protein 2, putative | 0.0254 | 0.2634 | 0.3396 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.0254 | 0.2634 | 0.3396 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0713 | 0.7748 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0713 | 0.7748 | 0.7747 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.004 | 0.0254 | 0.0328 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0223 | 0.0836 |
Schistosoma mansoni | hypothetical protein | 0.0254 | 0.2634 | 0.2964 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.0023 | 0.003 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0022 | 0.0057 | 0.0074 |
Leishmania major | trypanothione reductase | 0.005 | 0.0368 | 0.1386 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0254 | 0.2634 | 0.2631 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0815 | 0.8879 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0713 | 0.7748 | 0.7747 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0127 | 0.0163 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0385 | 0.0382 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0037 | 0.0223 | 0.0836 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0019 | 0.0023 | 0.003 |
Schistosoma mansoni | lamin | 0.0032 | 0.0165 | 0.0181 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0815 | 0.8879 | 0.8878 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.005 | 0.0368 | 0.0365 |
Brugia malayi | YY1-associated factor 2 | 0.0254 | 0.2634 | 0.3399 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0019 | 0.0023 | 0.0074 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.005 | 0.0368 | 0.2985 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0254 | 0.2634 | 0.2964 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0223 | 0.0288 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Plasmodium vivax | unspecified product | 0.0019 | 0.0023 | 0.0025 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0057 | 0.0204 |
Onchocerca volvulus | 0.0032 | 0.0165 | 0.0102 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.1384 | 0.525 |
Echinococcus granulosus | intermediate filament protein | 0.0032 | 0.0165 | 0.0181 |
Echinococcus multilocularis | geminin | 0.0548 | 0.5902 | 0.5901 |
Onchocerca volvulus | 0.0254 | 0.2634 | 0.3325 | |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0022 | 0.0057 | 0.0074 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0713 | 0.7748 | 0.8726 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0037 | 0.0223 | 0.0284 |
Brugia malayi | intermediate filament protein | 0.0032 | 0.0165 | 0.0212 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0035 | 0.0195 | 0.0251 |
Toxoplasma gondii | ran binding protein | 0.0254 | 0.2634 | 0.3396 |
Onchocerca volvulus | 0.0254 | 0.2634 | 0.3325 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2634 | 0.3399 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0195 | 0.0191 |
Brugia malayi | Cathepsin L-like precursor | 0.0025 | 0.0087 | 0.0112 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0027 | 0.0114 | 0.0111 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0165 | 0.0212 |
Brugia malayi | Thioredoxin reductase | 0.005 | 0.0368 | 0.0475 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0022 | 0.0057 | 0.0204 |
Onchocerca volvulus | 0.0254 | 0.2634 | 0.3325 | |
Brugia malayi | brahma associated protein 60 kDa | 0.0713 | 0.7748 | 1 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0027 | 0.0114 | 0.0125 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Plasmodium vivax | thioredoxin reductase, putative | 0.005 | 0.0368 | 0.0471 |
Toxoplasma gondii | thioredoxin reductase | 0.005 | 0.0368 | 0.0471 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0037 | 0.0223 | 0.022 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0254 | 0.2634 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.004 | 0.0254 | 0.0328 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0195 | 0.0215 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.004 | 0.0254 | 0.0328 |
Echinococcus granulosus | lamin | 0.0032 | 0.0165 | 0.0181 |
Trypanosoma brucei | trypanothione reductase | 0.005 | 0.0368 | 0.1386 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.1384 | 0.525 |
Plasmodium vivax | vivapain-1 | 0.0019 | 0.0023 | 0.0025 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0114 | 0.1083 | 0.8837 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.2634 | 0.3399 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0022 | 0.0057 | 0.4852 |
Brugia malayi | Cytochrome P450 family protein | 0.004 | 0.0254 | 0.0328 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0385 | 0.043 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0109 | 0.1025 | 0.1323 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0037 | 0.0223 | 0.0284 |
Echinococcus granulosus | tumor protein p63 | 0.035 | 0.3708 | 0.4175 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0037 | 0.0223 | 1 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0254 | 0.2634 | 0.2631 |
Trypanosoma cruzi | cytochrome P450, putative | 0.004 | 0.0254 | 0.0954 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Loa Loa (eye worm) | cysteine protease | 0.0037 | 0.0223 | 0.0288 |
Schistosoma mansoni | hypothetical protein | 0.0713 | 0.7748 | 0.8726 |
Trichomonas vaginalis | chaperonin, putative | 0.0027 | 0.0114 | 0.0143 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.006 | 0.0483 | 0.048 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0254 | 0.2634 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0037 | 0.0223 | 0.0288 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0017 | 0.0004 | 0.0005 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0195 | 0.0191 |
Onchocerca volvulus | 0.0254 | 0.2634 | 0.3325 | |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0195 | 0.0215 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0027 | 0.0114 | 0.0143 |
Echinococcus multilocularis | musashi | 0.0032 | 0.0165 | 0.0161 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.006 | 0.0483 | 0.054 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0037 | 0.0223 | 0.0284 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0057 | 0.0069 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0019 | 0.0023 | 0.0074 |
Loa Loa (eye worm) | fibroinase | 0.0037 | 0.0223 | 0.0288 |
Loa Loa (eye worm) | brahma associated protein | 0.0713 | 0.7748 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.004 | 0.0254 | 0.0954 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0223 | 0.0836 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0023 | 0.0025 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0027 | 0.0114 | 0.0143 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0027 | 0.0114 | 0.0143 |
Schistosoma mansoni | intermediate filament proteins | 0.0032 | 0.0165 | 0.0181 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0223 | 0.0836 |
Echinococcus granulosus | cathepsin L | 0.0019 | 0.0023 | 0.0022 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0127 | 0.1225 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.004 | 0.0254 | 0.0954 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.0057 | 0.0069 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Schistosoma mansoni | jumonji domain containing protein | 0.006 | 0.0483 | 0.054 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0035 | 0.0195 | 0.0215 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0037 | 0.0223 | 0.022 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0022 | 0.0057 | 0.0069 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0019 | 0.0023 | 0.0022 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0254 | 0.2634 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0025 | 0.0087 | 0.3182 |
Plasmodium falciparum | glutathione reductase | 0.005 | 0.0368 | 0.0471 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0713 | 0.7748 | 1 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0022 | 0.0057 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0019 | 0.0023 | 0.0025 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0027 | 0.0114 | 0.0421 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0195 | 0.0251 |
Echinococcus multilocularis | tumor protein p63 | 0.035 | 0.3708 | 0.3706 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.1384 | 0.525 |
Toxoplasma gondii | cathepsin CPL | 0.0037 | 0.0223 | 0.0284 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0713 | 0.7748 | 0.8726 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0032 | 0.0165 | 0.0212 |
Echinococcus multilocularis | cysteine protease | 0.0037 | 0.0223 | 0.022 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2634 | 0.3399 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0037 | 0.0223 | 0.0248 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0195 | 0.0215 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0114 | 0.1083 | 0.8837 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0641 | 0.0827 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0385 | 0.043 |
Schistosoma mansoni | lamin | 0.0032 | 0.0165 | 0.0181 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0254 | 0.2634 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0111 | 0.1048 | 0.3969 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0057 | 0.0061 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0022 | 0.0057 | 0.044 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0035 | 0.0195 | 0.0215 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0254 | 0.2634 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0037 | 0.0223 | 0.0248 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0037 | 0.0223 | 0.0288 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0254 | 0.2634 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0019 | 0.0023 | 0.0022 |
Echinococcus multilocularis | lamin dm0 | 0.0032 | 0.0165 | 0.0161 |
Schistosoma mansoni | zinc finger protein | 0.0254 | 0.2634 | 0.2964 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus granulosus | cathepsin l1 | 0.0025 | 0.0087 | 0.0094 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0254 | 0.2634 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0037 | 0.0223 | 0.0288 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0713 | 0.7748 | 0.7747 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0037 | 0.0223 | 0.0248 |
Loa Loa (eye worm) | intermediate filament protein | 0.0032 | 0.0165 | 0.0212 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0051 | 0.0381 | 0.0425 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0027 | 0.0114 | 0.0148 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2634 | 0.3399 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0815 | 0.8879 | 1 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0713 | 0.7748 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Loa Loa (eye worm) | glutathione reductase | 0.005 | 0.0368 | 0.0475 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.0385 | 0.0497 |
Loa Loa (eye worm) | CYP4Cod1 | 0.004 | 0.0254 | 0.0328 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0385 | 0.043 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0109 | 0.1025 | 0.1323 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0025 | 0.0087 | 0.0094 |
Loa Loa (eye worm) | thioredoxin reductase | 0.005 | 0.0368 | 0.0475 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0022 | 0.0057 | 0.0069 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0075 | 0.0641 | 0.0827 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Brugia malayi | cathepsin L-like precursor | 0.0025 | 0.0087 | 0.0112 |
Echinococcus multilocularis | GPCR, family 2 | 0.0035 | 0.0195 | 0.0191 |
Schistosoma mansoni | fusion | 0.0254 | 0.2634 | 0.2964 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.005 | 0.0368 | 0.1386 |
Echinococcus granulosus | lamin dm0 | 0.0032 | 0.0165 | 0.0181 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0027 | 0.0114 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0037 | 0.0223 | 0.0178 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0027 | 0.0114 | 0.0148 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0385 | 0.0382 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0087 | 0.0112 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | cysteine protease | 0.0037 | 0.0223 | 0.022 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0037 | 0.0223 | 0.022 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0127 | 0.1225 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Brugia malayi | glutathione reductase | 0.005 | 0.0368 | 0.0475 |
Schistosoma mansoni | hypothetical protein | 0.0075 | 0.0641 | 0.0718 |
Onchocerca volvulus | 0.0713 | 0.7748 | 1 | |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0019 | 0.0023 | 0.0074 |
Schistosoma mansoni | RNA binding protein | 0.0254 | 0.2634 | 0.2964 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Schistosoma mansoni | hypothetical protein | 0.0548 | 0.5902 | 0.6646 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0019 | 0.0023 | 0.0074 |
Plasmodium vivax | hypothetical protein, conserved | 0.0713 | 0.7748 | 1 |
Onchocerca volvulus | 0.0032 | 0.0165 | 0.0102 | |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0223 | 0.0836 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0019 | 0.0023 | 0.0022 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Toxoplasma gondii | exonuclease III APE | 0.0022 | 0.0057 | 0.0069 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0141 | 0.1384 | 0.525 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.0385 | 0.0497 |
Brugia malayi | Cathepsin L-like precursor | 0.0025 | 0.0087 | 0.0112 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Entamoeba histolytica | cysteine protease, putative | 0.0037 | 0.0223 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.2634 | 0.3399 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.2634 | 0.3399 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0254 | 0.2634 | 0.2631 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0114 | 0.1083 | 0.8837 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.006 | 0.0483 | 0.054 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.1384 | 0.525 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0022 | 0.0057 | 1 |
Echinococcus multilocularis | lamin | 0.0032 | 0.0165 | 0.0161 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0254 | 0.2634 | 0.2964 |
Onchocerca volvulus | Cathepsin L homolog | 0.0037 | 0.0223 | 0.0178 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0022 | 0.0057 | 0.1711 |
Plasmodium vivax | vivapain-3 | 0.0019 | 0.0023 | 0.0025 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0019 | 0.0023 | 0.0022 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.006 | 0.0483 | 0.054 |
Schistosoma mansoni | brg-1 associated factor | 0.0713 | 0.7748 | 0.8726 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0022 | 0.0057 | 0.0061 |
Schistosoma mansoni | ap endonuclease | 0.0022 | 0.0057 | 0.0061 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0027 | 0.0114 | 0.4558 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0713 | 0.7748 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Schistosoma mansoni | hypothetical protein | 0.0548 | 0.5902 | 0.6646 |
Leishmania major | cathepsin L-like protease | 0.0141 | 0.1384 | 0.525 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0027 | 0.0114 | 0.0125 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0087 | 0.0112 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Schistosoma mansoni | hypothetical protein | 0.0713 | 0.7748 | 0.8726 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0037 | 0.0223 | 0.022 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0019 | 0.0023 | 0.0025 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0254 | 0.2634 | 0.3399 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0027 | 0.0114 | 0.0421 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Trypanosoma cruzi | cysteine protease, putative | 0.0019 | 0.0023 | 0.0074 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0027 | 0.0114 | 0.0143 |
Onchocerca volvulus | Cathepsin F homolog | 0.0037 | 0.0223 | 0.0178 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0025 | 0.0087 | 0.0107 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0254 | 0.2634 | 1 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0027 | 0.0114 | 0.0421 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0032 | 0.0165 | 0.0212 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0022 | 0.0057 | 0.0204 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0713 | 0.7748 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Brugia malayi | jmjC domain containing protein | 0.006 | 0.0483 | 0.0623 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0025 | 0.0087 | 0.0107 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0037 | 0.0223 | 0.0248 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0385 | 0.043 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0129 | 0.1248 | 0.4731 |
Leishmania major | hypothetical protein, conserved | 0.0254 | 0.2634 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Mycobacterium tuberculosis | Probable reductase | 0.0114 | 0.1083 | 0.8837 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.004 | 0.0254 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0022 | 0.0057 | 0.2143 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.006 | 0.0483 | 0.0623 |
Brugia malayi | brahma associated protein 60 kDa | 0.0713 | 0.7748 | 1 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0713 | 0.7748 | 0.7747 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0114 | 0.1083 | 0.8837 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0254 | 0.2634 | 0.2964 |
Loa Loa (eye worm) | hypothetical protein | 0.0254 | 0.2634 | 0.3399 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0127 | 0.1225 | 1 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0254 | 0.2634 | 0.2964 |
Echinococcus granulosus | cysteine protease | 0.0019 | 0.0023 | 0.0022 |
Onchocerca volvulus | 0.0037 | 0.0223 | 0.0178 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0037 | 0.0223 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0713 | 0.7748 | 0.8726 |
Loa Loa (eye worm) | hypothetical protein | 0.0109 | 0.1025 | 0.1323 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0019 | 0.0023 | 0.0074 |
Plasmodium vivax | glutathione reductase, putative | 0.005 | 0.0368 | 0.0471 |
Plasmodium vivax | vivapain-2 | 0.0037 | 0.0223 | 0.0284 |
Leishmania major | cathepsin L-like protease | 0.0037 | 0.0223 | 0.0836 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0025 | 0.0087 | 0.0112 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0087 | 0.0112 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.006 | 0.0483 | 0.054 |
Plasmodium vivax | vivapain-2 | 0.0037 | 0.0223 | 0.0284 |
Echinococcus multilocularis | cathepsin L | 0.0019 | 0.0023 | 0.0019 |
Onchocerca volvulus | 0.0051 | 0.0381 | 0.0384 | |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0022 | 0.0057 | 0.0204 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0027 | 0.0114 | 0.0125 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0713 | 0.7748 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0713 | 0.7748 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0127 | 0.1225 | 1 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0254 | 0.2634 | 0.2964 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0254 | 0.2634 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0037 | 0.0223 | 0.0288 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0381 | 0.0491 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0713 | 0.7748 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.0195 | 0.0215 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0254 | 0.2634 | 0.2631 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0713 | 0.7748 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0022 | 0.0057 | 0.0054 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0027 | 0.0114 | 0.0148 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0141 | 0.1384 | 0.525 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0027 | 0.0114 | 0.0125 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0141 | 0.1384 | 0.525 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0109 | 0.1025 | 0.1323 |
Chlamydia trachomatis | SWIB complex protein | 0.0713 | 0.7748 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0035 | 0.0195 | 0.0251 |
Echinococcus granulosus | GPCR family 2 | 0.0035 | 0.0195 | 0.0215 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0035 | 0.0195 | 0.0251 |
Leishmania major | cytochrome p450-like protein | 0.004 | 0.0254 | 0.0954 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0158 | 0.0204 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0037 | 0.0223 | 0.0284 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.0254 | 0.2634 | 0.3325 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.006 | 0.0483 | 0.048 |
Leishmania major | cysteine peptidase A (CPA) | 0.0037 | 0.0223 | 0.0836 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0385 | 0.043 |
Brugia malayi | Cathepsin L-like precursor | 0.0037 | 0.0223 | 0.0288 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0114 | 0.1083 | 0.8837 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 22 uM | Inhibition of farnesyl transferase | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.