Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tumor protein p63 | 0.0351 | 0.3605 | 0.291 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0311 | 0.3115 | 0.8719 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0311 | 0.3115 | 0.2366 |
Mycobacterium ulcerans | hypothetical protein | 0.0183 | 0.1554 | 0.5 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0311 | 0.3115 | 0.2366 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0311 | 0.3115 | 0.2366 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0311 | 0.3115 | 0.8719 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0311 | 0.3115 | 0.8719 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0311 | 0.3115 | 0.2438 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0311 | 0.3115 | 0.8719 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0311 | 0.3115 | 0.8719 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0874 | 1 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0311 | 0.3115 | 0.8719 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0311 | 0.3115 | 0.8719 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0874 | 1 | 0.5 |
Loa Loa (eye worm) | brahma associated protein | 0.0874 | 1 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0311 | 0.3115 | 0.2366 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0165 | 0.1327 | 0.3643 |
Leishmania major | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Leishmania major | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Leishmania major | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0748 | 0.8453 | 0.8285 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0748 | 0.8453 | 0.8285 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.0311 | 0.3115 | 0.3115 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0311 | 0.3115 | 0.2366 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.3115 | 0.2438 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0874 | 1 | 1 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0874 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0147 | 0.1115 | 0.0148 |
Plasmodium vivax | hypothetical protein, conserved | 0.0874 | 1 | 0.5 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0311 | 0.3115 | 0.2366 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.3115 | 0.2438 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0874 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.8719 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0348 | 0.3567 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0874 | 1 | 0.5 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0234 | 0.2172 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0874 | 1 | 1 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0874 | 1 | 1 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0348 | 0.3567 | 1 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0311 | 0.3115 | 0.2366 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0311 | 0.3115 | 0.2438 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0874 | 1 | 1 |
Schistosoma mansoni | fusion | 0.0311 | 0.3115 | 0.2366 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0874 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.3115 | 0.2438 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.8719 |
Schistosoma mansoni | hypothetical protein | 0.0311 | 0.3115 | 0.2366 |
Brugia malayi | YY1-associated factor 2 | 0.0311 | 0.3115 | 0.2438 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0348 | 0.3567 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0311 | 0.3115 | 0.2438 |
Chlamydia trachomatis | SWIB complex protein | 0.0874 | 1 | 0.5 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0748 | 0.8453 | 0.8285 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0311 | 0.3115 | 0.2366 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.8719 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0147 | 0.1115 | 0.0148 |
Onchocerca volvulus | 0.0874 | 1 | 1 | |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0874 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.3115 | 0.2438 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0874 | 1 | 0.5 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0874 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0874 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0874 | 1 | 1 |
Schistosoma mansoni | RNA binding protein | 0.0311 | 0.3115 | 0.2366 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 0.3115 | 0.2438 |
Echinococcus multilocularis | tumor protein p63 | 0.0351 | 0.3605 | 0.291 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0348 | 0.3567 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0874 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0147 | 0.1115 | 0.0148 |
Toxoplasma gondii | ran binding protein | 0.0311 | 0.3115 | 0.3115 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0311 | 0.3115 | 0.2438 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0311 | 0.3115 | 0.2366 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0311 | 0.3115 | 0.7984 |
Schistosoma mansoni | brg-1 associated factor | 0.0874 | 1 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0311 | 0.3115 | 0.7984 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0311 | 0.3115 | 0.2366 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0874 | 1 | 1 |
Brugia malayi | brahma associated protein 60 kDa | 0.0874 | 1 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0874 | 1 | 1 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0311 | 0.3115 | 0.7984 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Acceptor activity (binding) | = 47.3 | Electron acceptor activity on bovine milk xanthine oxidase using xanthine as reducing substrate | ChEMBL. | 15163191 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.