Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hydrolase | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | Zn-dependent glyoxylase | 0.0101 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0101 | 0.5 | 0.5 |
Treponema pallidum | ribonuclease Z | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | hydroxyacylglutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | Beta-lactamase-like protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | POSSIBLE HYDROLASE | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible hydrolase | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0101 | 0.5 | 0.5 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | ETHE1 protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hydrolase | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Leishmania major | metallo-beta-lactamase family-like protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Leishmania major | cleavage and polyadenylation specificity factor, putative | 0.0101 | 0.5 | 0.5 |
Leishmania major | hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0101 | 0.5 | 0.5 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | Hydroxyacylglutathione hydrolase, mitochondrial homolog | 0.0101 | 0.5 | 0.5 |
Plasmodium falciparum | cytosolic glyoxalase II | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | cleavage and polyadenylation specificity factor subunit, putative | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0101 | 0.5 | 0.5 | |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0101 | 0.5 | 0.5 |
Brugia malayi | Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. | 0.0101 | 0.5 | 0.5 |
Leishmania major | metallo-beta-lactamase family protein-like protein | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0101 | 0.5 | 0.5 | |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | metallo-beta-lactamase-like protein, putative | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | Putative hydrolase PNKD | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Giardia lamblia | Metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Chlamydia trachomatis | ribonuclease Z | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | A-type flavoprotein | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible hydrolase | 0.0101 | 0.5 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | metallo-beta-lactamase superfamily hydrolase | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0101 | 0.5 | 0.5 |
Plasmodium vivax | hydroxyacyl glutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | glyoxalase II, GloB | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | beta lactamase-like protein | 0.0101 | 0.5 | 0.5 |
Toxoplasma gondii | metallo-beta-lactamase domain-containing protein | 0.0101 | 0.5 | 0.5 |
Toxoplasma gondii | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hydrolase | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | ETHE1 protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0101 | 0.5 | 0.5 |
Plasmodium vivax | unspecified product | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Beta lactamase like protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0101 | 0.5 | 0.5 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase cytoplasmic | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0101 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.