Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | Zn-dependent glyoxylase | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hydrolase | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Treponema pallidum | ribonuclease Z | 0.0101 | 0.5 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | Beta-lactamase-like protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | hydroxyacylglutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Brugia malayi | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | POSSIBLE HYDROLASE | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible hydrolase | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hydrolase | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | ETHE1 protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Leishmania major | metallo-beta-lactamase family-like protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Leishmania major | hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Leishmania major | cleavage and polyadenylation specificity factor, putative | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0101 | 0.5 | 0.5 |
Plasmodium falciparum | cytosolic glyoxalase II | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | Hydroxyacylglutathione hydrolase, mitochondrial homolog | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0101 | 0.5 | 0.5 | |
Trypanosoma brucei | cleavage and polyadenylation specificity factor subunit, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Leishmania major | metallo-beta-lactamase family protein-like protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Brugia malayi | Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma brucei | metallo-beta-lactamase-like protein, putative | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | 0.0101 | 0.5 | 0.5 | |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Onchocerca volvulus | Putative hydrolase PNKD | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Giardia lamblia | Metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Chlamydia trachomatis | ribonuclease Z | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | A-type flavoprotein | 0.0101 | 0.5 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | metallo-beta-lactamase superfamily hydrolase | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Possible hydrolase | 0.0101 | 0.5 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | glyoxalase II, GloB | 0.0101 | 0.5 | 0.5 |
Plasmodium vivax | hydroxyacyl glutathione hydrolase, putative | 0.0101 | 0.5 | 0.5 |
Toxoplasma gondii | metallo-beta-lactamase domain-containing protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | beta lactamase-like protein | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Toxoplasma gondii | hydroxyacylglutathione hydrolase | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hydrolase | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0101 | 0.5 | 0.5 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0101 | 0.5 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0101 | 0.5 | 0.5 |
Echinococcus granulosus | ETHE1 protein | 0.0101 | 0.5 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | glyoxalase II | 0.0101 | 0.5 | 0.5 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase cytoplasmic | 0.0101 | 0.5 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0101 | 0.5 | 0.5 |
Plasmodium vivax | unspecified product | 0.0101 | 0.5 | 0.5 |
Mycobacterium tuberculosis | Beta lactamase like protein | 0.0101 | 0.5 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0101 | 0.5 | 0.5 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0101 | 0.5 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.