Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.0149 | 0.1732 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | cysteine protease | 0.0029 | 0.086 | 0.0722 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | Dopamine receptor protein 1 | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0021 | 0.0274 | 0.0274 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0153 | 1 | 1 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0021 | 0.0274 | 0.0274 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | Melatonin receptor type 1A | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0029 | 0.086 | 1 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0149 | 0.1732 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0149 | 0.0149 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0149 | 0.0149 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0051 | 0.2513 | 0.24 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Dopamine receptor protein 2 | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin b | 0.0153 | 1 | 1 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Dopamine receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | RNA helicase, putative | 0.0138 | 0.8886 | 1 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus granulosus | sex peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G protein-coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0053 | 0.2688 | 1 |
Brugia malayi | ORL1-like opioid receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0051 | 0.2513 | 1 |
Brugia malayi | sulfakinin receptor protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0029 | 0.086 | 0.0722 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0051 | 0.2513 | 0.2513 |
Toxoplasma gondii | cathepsin B | 0.0053 | 0.2688 | 1 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0149 | 0.5 |
Echinococcus granulosus | somatostatin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0029 | 0.086 | 1 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.086 | 0.2619 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | allatostatin A receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0138 | 0.8886 | 0.8886 |
Brugia malayi | Serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0029 | 0.086 | 0.086 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0153 | 1 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0053 | 0.2688 | 0.2688 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | orexin receptor type 2 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 1 | 1 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0051 | 0.2513 | 0.2513 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | RE15519p | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0021 | 0.0274 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0053 | 0.2688 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0051 | 0.2513 | 0.24 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | g-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | myosin xvIII | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | G-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.086 | 0.0722 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Echinococcus granulosus | neuropeptide s receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | fibroinase | 0.0029 | 0.086 | 0.0722 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.086 | 1 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | GnHR receptor homolog | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin b | 0.0153 | 1 | 1 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | neuropeptide F receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | cysteine protease | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | sex peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin l1 | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0021 | 0.0274 | 0.0274 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Cathepsin F homolog | 0.0029 | 0.086 | 0.2619 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.0149 | 0.1732 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | allatostatin A receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0274 | 0.1018 |
Brugia malayi | follicle stimulating hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0029 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0149 | 0.0554 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0051 | 0.2513 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | neuropeptide F receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin b | 0.0153 | 1 | 1 |
Brugia malayi | AKH receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | Cathepsin L homolog | 0.0029 | 0.086 | 0.2619 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0029 | 0.086 | 0.086 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.0149 | 0.5 |
Brugia malayi | Serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | cathepsin b | 0.0153 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0021 | 0.0274 | 0.1018 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | putative neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.086 | 0.086 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.086 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0051 | 0.2513 | 0.2513 |
Toxoplasma gondii | cathepsin CPL | 0.0029 | 0.086 | 0.2802 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | larval opioid receptor | 0.0051 | 0.2513 | 0.2513 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0029 | 0.086 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | histamine h1 receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Leishmania major | cysteine peptidase A (CPA) | 0.0029 | 0.086 | 0.2802 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | fmrfamide receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine protease, putative | 0.0029 | 0.086 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0149 | 0.0149 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0051 | 0.2513 | 0.2513 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Echinococcus granulosus | cathepsin l1 | 0.0021 | 0.0274 | 0.0274 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0029 | 0.086 | 0.0722 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | amine GPCR | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Leishmania major | cathepsin L-like protease | 0.0029 | 0.086 | 0.2802 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Giardia lamblia | Cathepsin B precursor | 0.0053 | 0.2688 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0053 | 0.2688 | 0.2577 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0051 | 0.2513 | 0.2513 |
Plasmodium vivax | vivapain-2 | 0.0029 | 0.086 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | G-protein coupled receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | adenoreceptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0051 | 0.2513 | 0.24 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.0149 | 0.5 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0029 | 0.086 | 0.086 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0053 | 0.2688 | 0.2688 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0149 | 0.0554 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0274 | 0.0127 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0149 | 0.0149 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0029 | 0.086 | 0.086 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0051 | 0.2513 | 0.2513 |
Schistosoma mansoni | neuropeptide receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0053 | 0.2688 | 0.3024 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0021 | 0.0274 | 0.0274 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0029 | 0.086 | 0.2619 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0029 | 0.086 | 0.0968 |
Loa Loa (eye worm) | ctsf protein | 0.0029 | 0.086 | 0.0722 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.0149 | 0.0149 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Echinococcus granulosus | serotonin receptor | 0.0051 | 0.2513 | 0.2513 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.0149 | 0.0168 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2513 | 0.24 |
Brugia malayi | hypothetical protein | 0.0051 | 0.2513 | 0.2513 |
Onchocerca volvulus | 0.0051 | 0.2513 | 1 | |
Schistosoma mansoni | biogenic amine receptor | 0.0051 | 0.2513 | 0.2513 |
Echinococcus multilocularis | somatostatin receptor | 0.0051 | 0.2513 | 0.2513 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0029 | 0.086 | 0.3201 |
Schistosoma mansoni | opsin-like receptor | 0.0051 | 0.2513 | 0.2513 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0051 | 0.2513 | 0.24 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0153 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0029 | 0.086 | 0.086 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (functional) | = 2 % | The concentration to inhibit cell proliferation of PC3 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 3 % | The concentration to inhibit colony formation of PC3 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 4 % | The concentration to inhibit colony formation of MCF-7 human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 6 % | The concentration to inhibit colony formation of Ishikawa human tumour cell lines | ChEMBL. | 9341910 |
Inhibition (functional) | = 8 % | The concentration to inhibit cell proliferation of MCF-7 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 8 % | The concentration to inhibit cell proliferation of MDA-MB-231 human tumour cell lines using the sulforhodamine B assay | ChEMBL. | 9341910 |
Inhibition (functional) | = 15 % | The concentration to inhibit colony formation of MDA-MB-231 human tumour cell lines | ChEMBL. | 9341910 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.