Detailed information for compound 1747957

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 417.712 | Formula: C23H49N2O2S+
  • H donors: 0 H acceptors: 2 LogP: 7.45 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCCCCS(=O)(=O)N1CCC[N+](CC1)(C)C
  • InChi: 1S/C23H49N2O2S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-23-28(26,27)24-19-18-21-25(2,3)22-20-24/h4-23H2,1-3H3/q+1
  • InChiKey: NTOZJHJDVJZCAP-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0195 0.0798 0.8528
Mycobacterium ulcerans hypothetical protein 0.0027 0.005 0.1874
Schistosoma mansoni hypothetical protein 0.0111 0.0425 0.0425
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0023 0.0027
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0195 0.0798 0.8492
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0139 0.0549 1
Onchocerca volvulus 0.0039 0.0103 0.0877
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0023 0.0027
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0023 0.0027
Echinococcus granulosus lamin dm0 0.0031 0.0067 0.0067
Schistosoma mansoni intermediate filament proteins 0.0031 0.0067 0.0067
Echinococcus granulosus transcription factor Dp 1 0.008 0.0288 0.0288
Loa Loa (eye worm) hypothetical protein 0.0031 0.0065 0.0083
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0106 0.0913
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0023 0.0023
Schistosoma mansoni aldehyde dehydrogenase 0.0058 0.0185 0.0185
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.005 0.2112
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0023 0.0023
Plasmodium falciparum phd finger protein, putative 0.0028 0.0051 0.821
Echinococcus multilocularis jumonji domain containing protein 0.0038 0.01 0.01
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0051 0.0158 0.0207
Loa Loa (eye worm) hypothetical protein 0.004 0.0108 0.0141
Echinococcus granulosus neutral alpha glucosidase AB 0.0042 0.0115 0.0115
Trichomonas vaginalis sucrase-isomaltase, putative 0.0042 0.0115 0.0789
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0023 0.0023
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0021 0.0019 0.5
Mycobacterium ulcerans aldehyde dehydrogenase 0.0058 0.0185 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0027
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0057 0.0181 0.0181
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0192 0.1654
Loa Loa (eye worm) hypothetical protein 0.0195 0.0798 0.1058
Entamoeba histolytica hypothetical protein 0.0042 0.0114 0.085
Echinococcus multilocularis neutral alpha glucosidase AB 0.0042 0.0115 0.0115
Echinococcus multilocularis chromobox protein 1 0.0066 0.0223 0.0223
Echinococcus multilocularis geminin 0.0196 0.0805 0.0805
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0023 0.0027
Onchocerca volvulus 0.0031 0.0067 0.0489
Schistosoma mansoni tar DNA-binding protein 0.0147 0.0584 0.0584
Entamoeba histolytica rodhanase-like domain containing protein 0.0195 0.0798 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.005 0.5
Schistosoma mansoni hypothetical protein 0.0196 0.0805 0.0805
Schistosoma mansoni aminopeptidase P homologue (M24 family) 0.1698 0.752 0.752
Loa Loa (eye worm) hypothetical protein 0.0044 0.0127 0.0165
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0021 0.0023 0.0023
Onchocerca volvulus 0.0109 0.0416 0.4321
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0027 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0064
Loa Loa (eye worm) hypothetical protein 0.0173 0.0701 0.0929
Brugia malayi hypothetical protein 0.0042 0.0114 0.0148
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0023 0.0027
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0023 0.0023
Entamoeba histolytica hypothetical protein 0.0042 0.0114 0.085
Onchocerca volvulus Huntingtin homolog 0.0116 0.0447 0.4666
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0023 0.0023
Brugia malayi AMP-binding enzyme family protein 0.0027 0.005 0.0064
Trichomonas vaginalis chromobox protein, putative 0.004 0.0106 0.0687
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0023
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0192 0.2715
Brugia malayi hypothetical protein 0.0116 0.0447 0.0591
Loa Loa (eye worm) hypothetical protein 0.0179 0.073 0.0968
Loa Loa (eye worm) heterochromatin protein 1 0.0066 0.0223 0.0293
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0139 0.0549 0.0549
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0195 0.0798 0.8492
Trichomonas vaginalis chromobox protein, putative 0.004 0.0106 0.0687
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0023 0.0023
Echinococcus granulosus tar DNA binding protein 0.0147 0.0584 0.0584
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.005 0.1874
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0023
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0059 0.0192 0.2715
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0023 0.0027
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0115 0.0789
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0023 0.0023
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0023 0.0023
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0023
Echinococcus granulosus survival motor neuron protein 1 0.0224 0.093 0.093
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0023 0.0027
Schistosoma mansoni bromodomain containing protein 0.006 0.0196 0.0196
Trichomonas vaginalis set domain proteins, putative 0.0225 0.0932 1
Echinococcus multilocularis tar DNA binding protein 0.0147 0.0584 0.0584
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0163 0.0655 0.0868
Echinococcus granulosus chromobox protein 1 0.0066 0.0223 0.0223
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0059 0.0192 0.2828
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0027
Schistosoma mansoni hypothetical protein 0.0051 0.0158 0.0158
Brugia malayi Hyaluronidase family protein 0.1698 0.752 1
Schistosoma mansoni alpha-glucosidase 0.0162 0.0654 0.0654
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0023
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0115 0.0789
Onchocerca volvulus 0.0031 0.0067 0.0489
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0028 0.0054 0.0211
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0064
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0189 0.0771 0.1023
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0023 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0147 0.0584 0.0584
Echinococcus multilocularis mitogen activated protein kinase 3 0.0059 0.0192 0.0192
Trichomonas vaginalis cdc25b, putative 0.0195 0.0798 0.8492
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0085 0.0085
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0023 0.0023
Trichomonas vaginalis chromobox protein, putative 0.0066 0.0223 0.2008
Schistosoma mansoni aldehyde dehydrogenase 0.0058 0.0185 0.0185
Echinococcus granulosus lamin 0.0031 0.0067 0.0067
Schistosoma mansoni coup transcription factor 0.0021 0.0023 0.0023
Echinococcus granulosus mitogen activated protein kinase 3 0.0059 0.0192 0.0192
Loa Loa (eye worm) hypothetical protein 0.0721 0.3153 0.4191
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0115 0.0789
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0046 0.0132 0.0172
Loa Loa (eye worm) TAR-binding protein 0.0147 0.0584 0.0773
Brugia malayi latrophilin 2 splice variant baaae 0.0111 0.0425 0.0562
Schistosoma mansoni chromobox protein 0.0066 0.0223 0.0223
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0058 0.0495
Schistosoma mansoni Hyaluronidase 0.1698 0.752 0.752
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0192 0.1654
Loa Loa (eye worm) hypothetical protein 0.0067 0.0228 0.0299
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0139 0.0549 0.0727
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.005 0.1874
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0115 0.0789
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0058 1
Schistosoma mansoni hypothetical protein 0.0046 0.0132 0.0132
Onchocerca volvulus 0.0027 0.005 0.0304
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0058 1
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0192 0.1654
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0147 0.0584 0.0773
Echinococcus granulosus intermediate filament protein 0.0031 0.0067 0.0067
Brugia malayi Heterochromatin protein 1 0.0066 0.0223 0.0293
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0059 0.0192 0.2715
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0067 0.0086
Brugia malayi ecdysteroid receptor 0.0021 0.0023 0.0027
Echinococcus multilocularis musashi 0.0031 0.0067 0.0067
Schistosoma mansoni lamin 0.0031 0.0067 0.0067
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0023 0.0023
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0023 0.0023
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0023 0.0023
Mycobacterium ulcerans aldehyde dehydrogenase 0.0058 0.0185 1
Giardia lamblia Kinase, CMGC MAPK 0.0059 0.0192 1
Brugia malayi Bromodomain containing protein 0.0036 0.009 0.0116
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0058 0.0185 0.0185
Brugia malayi Pre-SET motif family protein 0.0197 0.081 0.1074
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0139 0.0549 0.0549
Echinococcus granulosus lysosomal alpha glucosidase 0.0189 0.0771 0.0771
Schistosoma mansoni transcription factor LCR-F1 0.0042 0.0114 0.0114
Schistosoma mansoni chromobox protein 0.0066 0.0223 0.0223
Schistosoma mansoni m-phase inducer phosphatase(cdc25) 0.0195 0.0798 0.0798
Loa Loa (eye worm) hypothetical protein 0.0195 0.0798 0.1058
Brugia malayi AMP-binding enzyme family protein 0.0027 0.005 0.0064
Brugia malayi hypothetical protein 0.0019 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0111 0.0425 0.0562
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0023 0.0027
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.005 0.5
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0139 0.0549 0.0727
Schistosoma mansoni hypothetical protein 0.0196 0.0805 0.0805
Loa Loa (eye worm) hypothetical protein 0.0029 0.0057 0.0073
Brugia malayi jmjC domain containing protein 0.0035 0.0085 0.011
Loa Loa (eye worm) PHD-finger family protein 0.0028 0.0051 0.0065
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0027
Echinococcus multilocularis zinc finger protein 0.0019 0.0011 0.0011
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.005 0.1874
Mycobacterium ulcerans aldehyde dehydrogenase 0.0058 0.0185 1
Trichomonas vaginalis cdc25c, putative 0.0195 0.0798 0.8492
Echinococcus multilocularis microtubule associated protein 2 0.2253 1 1
Entamoeba histolytica hypothetical protein 0.0042 0.0114 0.085
Loa Loa (eye worm) jmjC domain-containing protein 0.0057 0.0183 0.024
Loa Loa (eye worm) hypothetical protein 0.0036 0.009 0.0117
Entamoeba histolytica rodhanase-like domain containing protein 0.0195 0.0798 1
Schistosoma mansoni hypothetical protein 0.0051 0.0158 0.0158
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0023 0.0027
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0023 0.0023
Echinococcus granulosus jumonji domain containing protein 0.0038 0.01 0.01
Schistosoma mansoni hypothetical protein 0.002 0.0015 0.0015
Trichomonas vaginalis cdc25b, putative 0.0195 0.0798 0.8492
Schistosoma mansoni lamin 0.0031 0.0067 0.0067
Loa Loa (eye worm) hypothetical protein 0.0021 0.0019 0.0023
Entamoeba histolytica hypothetical protein 0.0042 0.0114 0.085
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0051 0.0158 0.0158
Loa Loa (eye worm) hypothetical protein 0.0163 0.0655 0.0868
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0027
Onchocerca volvulus 0.0195 0.0798 0.8528
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0042 0.0114 0.0114
Echinococcus granulosus geminin 0.0196 0.0805 0.0805
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0139 0.0549 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0139 0.0549 1
Schistosoma mansoni tar DNA-binding protein 0.0147 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.0051 0.0158 0.0207
Echinococcus multilocularis mitogen activated protein kinase 0.0059 0.0192 0.0192
Onchocerca volvulus Huntingtin homolog 0.0116 0.0447 0.4666
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0023 0.0027
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0023 0.0023
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0091 0.0332 0.0332
Schistosoma mansoni survival motor neuron protein 0.0046 0.0132 0.0132
Echinococcus multilocularis lamin 0.0031 0.0067 0.0067
Brugia malayi Glycosyl hydrolases family 31 protein 0.0189 0.0771 0.1023
Onchocerca volvulus 0.0225 0.0932 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0044 0.0127 0.0127
Echinococcus granulosus bifunctional protein NCOAT 0.1698 0.752 0.752
Loa Loa (eye worm) latrophilin receptor protein 2 0.0051 0.0158 0.0207
Brugia malayi Muscleblind-like protein 0.0173 0.0701 0.0929
Onchocerca volvulus 0.0046 0.0132 0.1202
Brugia malayi Bromodomain containing protein 0.0071 0.0246 0.0323
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0051 0.0158 0.0158
Echinococcus granulosus PHD finger protein rhinoceros 0.0028 0.0051 0.0051
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0058 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0027
Echinococcus granulosus histone lysine methyltransferase setb 0.0044 0.0127 0.0127
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0139 0.0549 0.0549
Schistosoma mansoni zinc finger protein 0.0019 0.0011 0.0011
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0085 0.011
Echinococcus multilocularis muscleblind protein 1 0.0173 0.0701 0.0701
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0115 0.0789
Loa Loa (eye worm) hypothetical protein 0.0047 0.014 0.0182
Trichomonas vaginalis mitotic inducer phosphatase CDC25, putative 0.0195 0.0798 0.8492
Trypanosoma brucei protein kinase, putative 0.0059 0.0192 0.2715
Echinococcus granulosus mitogen activated protein kinase 0.0059 0.0192 0.0192
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0021 0.0019 0.0294
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0127 0.0127
Brugia malayi TAR-binding protein 0.0147 0.0584 0.0773
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0023 0.0027
Echinococcus multilocularis chromobox protein 1 0.0066 0.0223 0.0223
Echinococcus granulosus fetal alzheimer antigen falz 0.0021 0.0023 0.0023
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0042 0.0115 0.015
Loa Loa (eye worm) hypothetical protein 0.0224 0.093 0.1234
Entamoeba histolytica rodhanase-like domain containing protein 0.0195 0.0798 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0023 0.0023
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0059 0.0192 0.2715
Echinococcus granulosus zinc finger protein 0.0019 0.0011 0.0011
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0093 0.0545
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0074
Brugia malayi Bromodomain containing protein 0.003 0.0061 0.0078
Brugia malayi RNA recognition motif domain containing protein 0.0147 0.0584 0.0773
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0023 0.0027
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0067 0.0086
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0028 0.0051 0.0051
Brugia malayi RNA binding protein 0.0147 0.0584 0.0773
Echinococcus multilocularis m phase inducer phosphatase(cdc25) 0.0195 0.0798 0.0798
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0023 0.0023
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0051 0.821
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0023 0.0027
Schistosoma mansoni jumonji domain containing protein 0.0072 0.0249 0.0249
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0195 0.0798 0.8492
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0139 0.0549 1
Leishmania major alpha glucosidase II subunit, putative 0.0042 0.0115 0.1292
Schistosoma mansoni alpha-glucosidase 0.0162 0.0654 0.0654
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.005 0.1874
Echinococcus granulosus peregrin 0.003 0.0061 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0093 0.0545
Echinococcus multilocularis survival motor neuron protein 1 0.0224 0.093 0.093
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0023 0.0027
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0023 0.0023
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0067 0.0086
Echinococcus multilocularis transcription factor Dp 1 0.008 0.0288 0.0288
Schistosoma mansoni tar DNA-binding protein 0.0147 0.0584 0.0584
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0058 0.0185 0.0185
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0023 0.0027
Loa Loa (eye worm) hyaluronidase 0.1698 0.752 1
Loa Loa (eye worm) RNA binding protein 0.0147 0.0584 0.0773
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0023 0.0027
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.005 0.2112
Brugia malayi chromobox protein homolog 3 0.0037 0.0093 0.0121
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.005 0.1874
Leishmania major hypothetical protein, conserved 0.0029 0.0058 0.0155
Schistosoma mansoni tar DNA-binding protein 0.0147 0.0584 0.0584
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.0037 0.0093 0.0121
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0115 0.1154
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0042 0.0114 0.0114
Echinococcus multilocularis lysosomal alpha glucosidase 0.0189 0.0771 0.0771
Schistosoma mansoni hypothetical protein 0.0051 0.0158 0.0158
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0044 0.0127 0.0127
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0057 0.0181 0.0181
Loa Loa (eye worm) hypothetical protein 0.0027 0.005 0.0064
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0027
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0115 0.1154
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0023 0.0023
Trichomonas vaginalis maltase-glucoamylase, putative 0.0042 0.0115 0.0789
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0039 0.0103 0.0103
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0051 0.0158 0.0158
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0023 0.0023
Echinococcus multilocularis lysosomal alpha glucosidase 0.0189 0.0771 0.0771
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0054 0.0054
Trichomonas vaginalis m-phase inducer phosphatase, putative 0.0195 0.0798 0.8492
Loa Loa (eye worm) hypothetical protein 0.0039 0.01 0.013
Brugia malayi AMP-binding enzyme family protein 0.0027 0.005 0.0064
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0115 0.0789
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0023 0.0027
Brugia malayi hypothetical protein 0.0224 0.093 0.1234
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0023 0.0023
Schistosoma mansoni hypothetical protein 0.0028 0.0051 0.0051
Brugia malayi jmjC domain containing protein 0.0091 0.0332 0.0439
Echinococcus multilocularis lamin dm0 0.0031 0.0067 0.0067
Onchocerca volvulus 0.0195 0.0798 0.8528
Loa Loa (eye worm) PHD-finger family protein 0.002 0.0015 0.0017
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0059 0.0192 0.0251
Brugia malayi PHD-finger family protein 0.0028 0.0051 0.0065
Brugia malayi PHD-finger family protein 0.0024 0.0033 0.0041
Brugia malayi intermediate filament protein 0.0031 0.0067 0.0086
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0023 0.0027
Brugia malayi Latrophilin receptor protein 2 0.0051 0.0158 0.0207
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0115 0.0862
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0023 0.0023
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0023 0.0027
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0197 0.081 0.1074
Schistosoma mansoni hypothetical protein 0.0042 0.0114 0.0114
Echinococcus multilocularis peregrin 0.003 0.0061 0.0061
Loa Loa (eye worm) hypothetical protein 0.0031 0.0067 0.0086
Brugia malayi steroid hormone receptor 0.0021 0.0023 0.0027
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0115 0.0789
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.005 0.1874
Brugia malayi Pre-SET motif family protein 0.0028 0.0054 0.0069
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0021 0.0023 0.0023
Onchocerca volvulus 0.0029 0.0057 0.0381
Brugia malayi MAP kinase sur-1 0.0059 0.0192 0.0251
Loa Loa (eye worm) hypothetical protein 0.0116 0.0447 0.0591
Echinococcus multilocularis GPCR, family 2 0.0051 0.0158 0.0158
Brugia malayi nuclear receptor NHR-88 0.0021 0.0023 0.0027
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0027
Trichomonas vaginalis chromobox protein, putative 0.0066 0.0223 0.2008
Echinococcus multilocularis bifunctional protein NCOAT 0.1698 0.752 0.752
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0091 0.0332 0.0332
Brugia malayi Rhodanese-like domain containing protein 0.0195 0.0798 0.1058
Loa Loa (eye worm) hypothetical protein 0.0179 0.073 0.0968
Schistosoma mansoni alpha glucosidase 0.0042 0.0115 0.0115
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0115 0.0862
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0023 0.0023
Brugia malayi Rhodanese-like domain containing protein 0.0195 0.0798 0.1058
Loa Loa (eye worm) hypothetical protein 0.0116 0.0447 0.0591
Schistosoma mansoni hypothetical protein 0.0051 0.0158 0.0158
Toxoplasma gondii aldehyde dehydrogenase 0.0058 0.0185 0.9539
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.005 0.1874
Schistosoma mansoni microtubule-associated protein tau 0.2253 1 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0163 0.0655 0.0868
Schistosoma mansoni jumonji/arid domain-containing protein 0.0035 0.0085 0.0085
Loa Loa (eye worm) hypothetical protein 0.0028 0.0051 0.0065
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0023 0.0027
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0059 0.0192 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0058 0.0185 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0058 0.0185 0.2698
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0051 0.0158 0.0158
Onchocerca volvulus Alhambra homolog 0.0028 0.0051 0.0313
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0163 0.0655 0.0868
Brugia malayi nuclear hormone receptor 0.0021 0.0023 0.0027
Echinococcus granulosus GPCR family 2 0.0051 0.0158 0.0158
Echinococcus granulosus lysine specific demethylase 5A 0.0035 0.0085 0.0085
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0023 0.0027
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0059 0.0192 0.2828
Plasmodium vivax SET domain protein, putative 0.0028 0.0054 0.8972
Loa Loa (eye worm) hypothetical protein 0.0173 0.0701 0.0929
Brugia malayi hypothetical protein 0.0029 0.0058 0.0074
Echinococcus granulosus chromobox protein 1 0.0066 0.0223 0.0223
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0192 0.0192
Trichomonas vaginalis CMGC family protein kinase 0.0059 0.0192 0.1654
Echinococcus multilocularis muscleblind protein 0.0173 0.0701 0.0701
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0034 0.008 0.008
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0042 0.0115 0.4536
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0023 0.0023
Echinococcus multilocularis lysine specific demethylase 5A 0.0033 0.0077 0.0077
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0023 0.0023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0028 0.0054 0.0054
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0139 0.0549 0.6674
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0023 0.0027
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0059 0.0192 0.2715
Echinococcus granulosus m phase inducer phosphatasecdc25 0.0195 0.0798 0.0798
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0023 0.0023
Echinococcus granulosus muscleblind protein 0.0173 0.0701 0.0701
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0023 0.0023
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0037 0.0093 0.0774
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0034 0.008 0.008
Brugia malayi Glycosyl hydrolases family 31 protein 0.0042 0.0115 0.015
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0023 0.0027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0023 0.0023
Echinococcus multilocularis PHD finger protein rhinoceros 0.0028 0.0051 0.0051
Onchocerca volvulus 0.0195 0.0798 0.8528
Trypanosoma brucei glucosidase, putative 0.0042 0.0115 0.1154

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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