Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0215 | 0.5175 | 0.5 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0215 | 0.5175 | 0.5175 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0215 | 0.5175 | 0.5175 |
Trypanosoma cruzi | glyoxalase II | 0.0215 | 0.5175 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0215 | 0.5175 | 0.5 |
Echinococcus granulosus | ETHE1 protein | 0.0215 | 0.5175 | 0.5 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0215 | 0.5175 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0215 | 0.5175 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 1 | 1 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0215 | 0.5175 | 0.5 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0215 | 0.5175 | 0.5 |
Onchocerca volvulus | Putative hydrolase PNKD | 0.0215 | 0.5175 | 1 |
Mycobacterium tuberculosis | Possible hydrolase | 0.0215 | 0.5175 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0215 | 0.5175 | 0.5175 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0215 | 0.5175 | 0.5175 |
Mycobacterium leprae | POSSIBLE HYDROLASE | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0178 | 0.1027 | 0.1027 |
Mycobacterium ulcerans | hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Mycobacterium ulcerans | Zn-dependent glyoxylase | 0.0215 | 0.5175 | 0.5 |
Chlamydia trachomatis | ribonuclease Z | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 1 | 1 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0215 | 0.5175 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0215 | 0.5175 | 0.5 |
Mycobacterium tuberculosis | Possible hydrolase | 0.0215 | 0.5175 | 0.5 |
Echinococcus granulosus | zinc phosphodiesterase | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0215 | 0.5175 | 0.5175 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0215 | 0.5175 | 0.5175 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0215 | 0.5175 | 0.5 |
Plasmodium vivax | unspecified product | 0.0215 | 0.5175 | 0.5 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | A-type flavoprotein | 0.0215 | 0.5175 | 0.5175 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0215 | 0.5175 | 0.5175 |
Mycobacterium leprae | conserved hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Toxoplasma gondii | hydroxyacylglutathione hydrolase | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0215 | 0.5175 | 0.5175 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Mycobacterium ulcerans | beta lactamase-like protein | 0.0215 | 0.5175 | 0.5 |
Leishmania major | metallo-beta-lactamase family protein-like protein | 0.0215 | 0.5175 | 0.5 |
Toxoplasma gondii | metallo-beta-lactamase domain-containing protein | 0.0215 | 0.5175 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0215 | 0.5175 | 0.5 |
Echinococcus granulosus | hydroxyacylglutathione hydrolase | 0.0215 | 0.5175 | 0.5 |
Trypanosoma cruzi | glyoxalase II | 0.0215 | 0.5175 | 0.5 |
Trypanosoma brucei | hydroxyacylglutathione hydrolase, putative | 0.0215 | 0.5175 | 0.5 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0215 | 0.5175 | 0.5 |
Plasmodium falciparum | cytosolic glyoxalase II | 0.0215 | 0.5175 | 0.5 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Onchocerca volvulus | 0.0215 | 0.5175 | 1 | |
Wolbachia endosymbiont of Brugia malayi | metallo-beta-lactamase superfamily hydrolase | 0.0215 | 0.5175 | 0.5 |
Echinococcus multilocularis | zinc phosphodiesterase | 0.0215 | 0.5175 | 0.5 |
Trypanosoma brucei | glyoxalase II | 0.0215 | 0.5175 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0215 | 0.5175 | 0.5 |
Plasmodium vivax | hydroxyacyl glutathione hydrolase, putative | 0.0215 | 0.5175 | 0.5 |
Mycobacterium ulcerans | hydrolase | 0.0215 | 0.5175 | 0.5 |
Giardia lamblia | Hydroxyacylglutathione hydrolase | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0215 | 0.5175 | 0.5175 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0215 | 0.5175 | 0.5 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0215 | 0.5175 | 0.5 |
Mycobacterium ulcerans | glyoxalase II, GloB | 0.0215 | 0.5175 | 0.5 |
Leishmania major | hydroxyacylglutathione hydrolase, putative,glyoxalase II, putative | 0.0215 | 0.5175 | 0.5 |
Onchocerca volvulus | Hydroxyacylglutathione hydrolase, mitochondrial homolog | 0.0215 | 0.5175 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0178 | 0.1027 | 0.1027 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0215 | 0.5175 | 0.5175 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0215 | 0.5175 | 0.5175 |
Mycobacterium tuberculosis | Conserved protein | 0.0215 | 0.5175 | 0.5 |
Onchocerca volvulus | 0.0215 | 0.5175 | 1 | |
Leishmania major | metallo-beta-lactamase family-like protein | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0215 | 0.5175 | 0.5175 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Mycobacterium leprae | conserved hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Trypanosoma brucei | cleavage and polyadenylation specificity factor subunit, putative | 0.0215 | 0.5175 | 0.5 |
Trypanosoma brucei | metallo-beta-lactamase-like protein, putative | 0.0215 | 0.5175 | 0.5 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0215 | 0.5175 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0215 | 0.5175 | 0.5 |
Echinococcus multilocularis | ETHE1 protein | 0.0215 | 0.5175 | 0.5 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0215 | 0.5175 | 0.5175 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 1 | 1 |
Giardia lamblia | Metallo-beta-lactamase superfamily protein | 0.0215 | 0.5175 | 0.5 |
Treponema pallidum | ribonuclease Z | 0.0215 | 0.5175 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Leishmania major | cleavage and polyadenylation specificity factor, putative | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0215 | 0.5175 | 0.5175 |
Schistosoma mansoni | hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) | 0.0215 | 0.5175 | 0.5 |
Mycobacterium leprae | Beta-lactamase-like protein | 0.0215 | 0.5175 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0258 | 1 | 1 |
Echinococcus multilocularis | hydroxyacylglutathione hydrolase | 0.0215 | 0.5175 | 0.5 |
Mycobacterium tuberculosis | Conserved protein | 0.0215 | 0.5175 | 0.5 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0258 | 1 | 1 |
Mycobacterium ulcerans | hydrolase | 0.0215 | 0.5175 | 0.5 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0215 | 0.5175 | 0.5 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0215 | 0.5175 | 0.5 |
Mycobacterium tuberculosis | Beta lactamase like protein | 0.0215 | 0.5175 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0215 | 0.5175 | 0.5 |
Mycobacterium ulcerans | hydrolase | 0.0215 | 0.5175 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0215 | 0.5175 | 0.5 |
Trypanosoma cruzi | glyoxalase II | 0.0215 | 0.5175 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.