Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0176 | 0.1673 | 0.0425 | |
Entamoeba histolytica | protein kinase domain containing protein | 0.0099 | 0.042 | 1 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0166 | 0.1513 | 0.1719 |
Brugia malayi | Sema domain containing protein | 0.0166 | 0.1513 | 0.1719 |
Brugia malayi | Sodium:solute symporter family protein | 0.0176 | 0.1673 | 0.19 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0073 | 0 | 0.5 |
Loa Loa (eye worm) | TK/FAK protein kinase | 0.0616 | 0.8802 | 1 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0176 | 0.1673 | 0.1673 |
Schistosoma mansoni | inositol transporter | 0.069 | 1 | 1 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0073 | 0.0002 | 0.0003 |
Echinococcus multilocularis | protein tyrosine kinase | 0.0609 | 0.8689 | 0.8689 |
Echinococcus granulosus | macrophage colony stimulating factor 1 receptor | 0.0626 | 0.8953 | 0.8953 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.1513 | 0.1513 |
Schistosoma mansoni | semaphorin 5-related | 0.0166 | 0.1513 | 0.1513 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1513 | 0.1719 |
Echinococcus granulosus | diacylglycerol O acyltransferase 1 | 0.0148 | 0.122 | 0.122 |
Schistosoma mansoni | high-affinity choline transporter | 0.0176 | 0.1673 | 0.1673 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0 | 0.5 |
Brugia malayi | Plexin repeat family protein | 0.0398 | 0.5266 | 0.5983 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0176 | 0.1673 | 0.1673 |
Brugia malayi | Sema domain containing protein | 0.0166 | 0.1513 | 0.1719 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.069 | 1 | 1 |
Schistosoma mansoni | plexin | 0.0398 | 0.5266 | 0.5266 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0176 | 0.1673 | 0.19 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1513 | 0.1719 |
Loa Loa (eye worm) | diacylglycerol acyltransferase | 0.0148 | 0.122 | 0.1386 |
Echinococcus multilocularis | semaphorin 5B | 0.0166 | 0.1513 | 0.1513 |
Schistosoma mansoni | hypothetical protein | 0.0232 | 0.2573 | 0.2573 |
Brugia malayi | hypothetical protein | 0.0166 | 0.1513 | 0.1719 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0176 | 0.1673 | 1 |
Echinococcus multilocularis | plexin a4 | 0.0471 | 0.6446 | 0.6446 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1513 | 0.1719 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0616 | 0.8802 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0123 | 0.0817 | 0.0928 |
Schistosoma mansoni | diacylglycerol O-acyltransferase 1 | 0.0148 | 0.122 | 0.122 |
Plasmodium falciparum | diacylglycerol O-acyltransferase | 0.0148 | 0.122 | 0.5 |
Brugia malayi | GH02984p | 0.0176 | 0.1673 | 0.19 |
Echinococcus granulosus | semaphorin 5B | 0.0166 | 0.1513 | 0.1513 |
Schistosoma mansoni | sodium/solute symporter | 0.0176 | 0.1673 | 0.1673 |
Loa Loa (eye worm) | hypothetical protein | 0.0398 | 0.5266 | 0.5983 |
Loa Loa (eye worm) | hypothetical protein | 0.0232 | 0.2573 | 0.2923 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1513 | 0.1719 |
Echinococcus granulosus | solute carrier family 5 | 0.069 | 1 | 1 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0073 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0176 | 0.1673 | 0.19 |
Echinococcus granulosus | semaphorin 1A | 0.0166 | 0.1513 | 0.1513 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0176 | 0.1673 | 0.1673 |
Entamoeba histolytica | tyrosin kinase, putative | 0.0099 | 0.042 | 1 |
Brugia malayi | diacylglycerol acyltransferase | 0.0148 | 0.122 | 0.1386 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.069 | 1 | 1 |
Echinococcus multilocularis | hypothetical protein | 0.0166 | 0.1513 | 0.1513 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.1513 | 0.1513 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1513 | 0.1719 |
Onchocerca volvulus | 0.0398 | 0.5266 | 1 | |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0073 | 0 | 0.5 |
Loa Loa (eye worm) | sema domain-containing protein | 0.0166 | 0.1513 | 0.1719 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0073 | 0.0002 | 0.0003 |
Loa Loa (eye worm) | plexin A | 0.0471 | 0.6446 | 0.7324 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0073 | 0 | 0.5 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.069 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0166 | 0.1513 | 0.1719 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 5 | 0.069 | 1 | 1 |
Trichomonas vaginalis | Clan MA, family M8, leishmanolysin-like metallopeptidase | 0.0073 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0073 | 0 | 0.5 |
Plasmodium vivax | diacylglycerol O-acyltransferase, putative | 0.0148 | 0.122 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1513 | 0.1719 |
Echinococcus granulosus | plexin a4 | 0.0471 | 0.6446 | 0.6446 |
Schistosoma mansoni | plexin | 0.0232 | 0.2573 | 0.2573 |
Brugia malayi | plexin A | 0.0471 | 0.6446 | 0.7324 |
Schistosoma mansoni | tyrosine kinase | 0.0609 | 0.8689 | 0.8689 |
Echinococcus multilocularis | diacylglycerol O acyltransferase 1 | 0.0148 | 0.122 | 0.122 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.069 | 1 | 1 |
Echinococcus granulosus | protein tyrosine kinase | 0.0609 | 0.8689 | 0.8689 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0176 | 0.1673 | 0.1673 |
Schistosoma mansoni | inositol transporter | 0.069 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.