Detailed information for compound 176081

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 246.326 | Formula: C18H16N+
  • H donors: 0 H acceptors: 0 LogP: 4.59 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[n+]1ccc(c2c1cccc2)/C=C/c1ccccc1
  • InChi: 1S/C18H16N/c1-19-14-13-16(17-9-5-6-10-18(17)19)12-11-15-7-3-2-4-8-15/h2-14H,1H3/q+1/b12-11+
  • InChiKey: QDMHYLUMTJATFS-VAWYXSNFSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens choline O-acetyltransferase Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Schistosoma japonicum ko:K00623 choline O-acetyltransferase [EC2.3.1.6], putative Get druggable targets OG5_133080 All targets in OG5_133080
Echinococcus multilocularis choline O acetyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Loa Loa (eye worm) choline O-acetyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Echinococcus granulosus choline O acetyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Brugia malayi Choline O-acetyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Brugia malayi Choline O-acetyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Schistosoma mansoni choline o-acyltransferase Get druggable targets OG5_133080 All targets in OG5_133080
Schistosoma japonicum Choline O-acetyltransferase, putative Get druggable targets OG5_133080 All targets in OG5_133080
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_133080 All targets in OG5_133080
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Trypanosoma brucei carnitine O-acetyltransferase, putative choline O-acetyltransferase 630 aa 632 aa 31.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0154 0.0871 0.1808
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0154 0.0871 0.1808
Brugia malayi Papain family cysteine protease containing protein 0.0154 0.0871 0.1235
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Schistosoma mansoni phd/f-box containing protein 0.0048 0.0157 0.0208
Trichomonas vaginalis chromobox protein, putative 0.0092 0.0451 0.0451
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0154 0.0871 0.1233
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.003 0.003 0.0043
Schistosoma mansoni protein phosphatase 2C 0.0048 0.0157 0.0208
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Onchocerca volvulus 0.0154 0.0871 0.1786
Echinococcus granulosus cathepsin l1 0.0709 0.4635 0.6643
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0154 0.0871 0.0871
Brugia malayi Importin beta-1 subunit 0.0031 0.004 0.0042
Schistosoma mansoni cathepsin F (C01 family) 0.0709 0.4635 0.6643
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.049 0.3153 0.4513
Loa Loa (eye worm) hypothetical protein 0.0225 0.1356 0.1931
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Echinococcus granulosus snurportin 1 0.033 0.2068 0.2955
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Brugia malayi Papain family cysteine protease containing protein 0.0154 0.0871 0.1235
Loa Loa (eye worm) hypothetical protein 0.0709 0.4635 0.6643
Trypanosoma cruzi cysteine proteinase, putative 0.0379 0.2397 0.3438
Plasmodium vivax hypothetical protein, conserved 0.0049 0.0162 0.0265
Entamoeba histolytica cysteine proteinase 1, putative 0.0379 0.2397 0.2397
Brugia malayi Cathepsin L-like precursor 0.0484 0.3109 0.4451
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0157 0.0208
Loa Loa (eye worm) hypothetical protein 0.0484 0.3109 0.445
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0064 0.0263 0.036
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0031 0.0043 0.0007
Trichomonas vaginalis chromobox protein, putative 0.0152 0.086 0.086
Brugia malayi jmjC domain containing protein 0.0048 0.0157 0.0211
Brugia malayi CHD4 protein 0.0027 0.0012 0.0003
Giardia lamblia Cathepsin L-like protease 0.0154 0.0871 0.0831
Brugia malayi Papain family cysteine protease containing protein 0.0709 0.4635 0.6644
Trichomonas vaginalis chromobox protein, putative 0.0092 0.0451 0.0451
Echinococcus granulosus cysteine protease 0.0379 0.2397 0.3426
Trypanosoma cruzi cruzipain precursor, putative 0.0709 0.4635 0.6649
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0432 0.2757 0.3945
Brugia malayi Papain family cysteine protease containing protein 0.0379 0.2397 0.3428
Giardia lamblia Cathepsin B precursor 0.0154 0.0871 0.0831
Trypanosoma cruzi cysteine peptidase, putative 0.0709 0.4635 0.6649
Plasmodium vivax flap endonuclease 1, putative 0.0031 0.0043 0.0007
Giardia lamblia Cathepsin B precursor 0.0432 0.2757 0.2726
Brugia malayi Heterochromatin protein 1 0.0152 0.086 0.122
Entamoeba histolytica cysteine proteinase 2 0.0379 0.2397 0.2397
Loa Loa (eye worm) hypothetical protein 0.1054 0.6971 1
Echinococcus granulosus lysine specific demethylase 5A 0.0183 0.1072 0.1522
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1054 0.6971 1
Echinococcus granulosus flap endonuclease 1 0.0031 0.0043 0.0044
Onchocerca volvulus 0.0484 0.3109 0.6544
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0154 0.0871 0.1233
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Brugia malayi hypothetical protein 0.0365 0.2302 0.3293
Brugia malayi AF-10 protein 0.0049 0.0162 0.0217
Brugia malayi Pre-SET motif family protein 0.0091 0.0448 0.0628
Brugia malayi PHD-finger family protein 0.015 0.0844 0.1198
Schistosoma mansoni hypothetical protein 0.015 0.0844 0.1196
Echinococcus granulosus histone lysine methyltransferase setb 0.0109 0.0572 0.0804
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.004 0.0021
Trypanosoma cruzi carnitine O-palmitoyltransferase II, putative 0.003 0.003 0.0043
Plasmodium falciparum cysteine proteinase falcipain 1 0.0379 0.2397 0.5129
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Onchocerca volvulus 0.0116 0.0617 0.1247
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0484 0.3109 0.446
Loa Loa (eye worm) hypothetical protein 0.0225 0.1356 0.1931
Echinococcus granulosus cathepsin b 0.1054 0.6971 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0225 0.1356 0.1931
Loa Loa (eye worm) hypothetical protein 0.0257 0.1569 0.2237
Loa Loa (eye worm) hypothetical protein 0.0041 0.0108 0.0138
Echinococcus granulosus cathepsin L 0.0154 0.0871 0.1233
Schistosoma mansoni hypothetical protein 0.033 0.2068 0.2955
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0448 0.0626
Entamoeba histolytica cysteine proteinase, putative 0.0379 0.2397 0.2397
Echinococcus multilocularis cathepsin L cysteine protease 0.0709 0.4635 0.6643
Trichomonas vaginalis flap endonuclease-1, putative 0.0031 0.0043 0.0043
Brugia malayi cathepsin L precursor 0.0154 0.0871 0.1235
Echinococcus multilocularis carnitine O palmitoyltransferase 1, liver 0.003 0.003 0.0026
Plasmodium falciparum cysteine proteinase falcipain 3 0.0709 0.4635 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0225 0.1356 0.1933
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0225 0.1356 0.1933
Brugia malayi hypothetical protein 0.0106 0.0551 0.0776
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0733 0.4798 0.5
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0088 0.0425 0.0593
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Echinococcus multilocularis cathepsin b 0.1054 0.6971 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0484 0.3109 0.3109
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Echinococcus granulosus carnitine O palmitoyltransferase 2 0.003 0.003 0.0026
Toxoplasma gondii PHD-finger domain-containing protein 0.015 0.0844 0.1751
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.1501 1 1
Onchocerca volvulus 0.0724 0.4735 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0154 0.0871 0.0871
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Toxoplasma gondii cathepsin CPC2 0.0154 0.0871 0.1808
Onchocerca volvulus 0.0365 0.2302 0.483
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.003 0.003 0.0028
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0157 0.0208
Brugia malayi Flap endonuclease-1 0.0031 0.0043 0.0047
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.003 0.0043
Echinococcus granulosus cathepsin l1 0.0484 0.3109 0.445
Echinococcus granulosus cathepsin l cysteine peptidase 0.0709 0.4635 0.6643
Echinococcus multilocularis lysine specific demethylase 5A 0.0181 0.1058 0.1502
Loa Loa (eye worm) hypothetical protein 0.0051 0.0175 0.0234
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Brugia malayi chromobox protein homolog 3 0.0085 0.0407 0.057
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0709 0.4635 1
Trypanosoma cruzi cysteine peptidase, putative 0.0709 0.4635 0.6649
Loa Loa (eye worm) fibroinase 0.0709 0.4635 0.6643
Echinococcus granulosus carnitine O palmitoyltransferase 1 liver 0.003 0.003 0.0026
Loa Loa (eye worm) hypothetical protein 0.003 0.003 0.0026
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0154 0.0871 0.1233
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0407 0.0407
Giardia lamblia PHD finger protein 15 0.015 0.0844 0.0805
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Loa Loa (eye worm) hypothetical protein 0.0067 0.0283 0.0388
Trypanosoma cruzi major cysteine proteinase, putative 0.0154 0.0871 0.1249
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Entamoeba histolytica hypothetical protein 0.0154 0.0871 0.0871
Plasmodium vivax SET domain protein, putative 0.0091 0.0448 0.0889
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0379 0.2397 0.2397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0709 0.4635 0.4635
Loa Loa (eye worm) hypothetical protein 0.0048 0.0157 0.0208
Entamoeba histolytica cysteine proteinase, putative 0.0709 0.4635 0.4635
Plasmodium falciparum serine repeat antigen 3 0.0154 0.0871 0.1808
Onchocerca volvulus 0.0709 0.4635 0.9788
Loa Loa (eye worm) hypothetical protein 0.0106 0.0551 0.0774
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Plasmodium falciparum phd finger protein, putative 0.015 0.0844 0.1751
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0379 0.2397 0.3426
Onchocerca volvulus 0.0709 0.4635 0.9788
Echinococcus multilocularis JmjC domain containing protein 4 0.0048 0.0157 0.0208
Onchocerca volvulus 0.0709 0.4635 0.9788
Echinococcus granulosus JmjC domain containing protein 4 0.0048 0.0157 0.0208
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0154 0.0871 0.1233
Onchocerca volvulus 0.0709 0.4635 0.9788
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.003 0.0043
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Giardia lamblia Cathepsin B precursor 0.0432 0.2757 0.2726
Toxoplasma gondii preprocathepsin c precursor, putative 0.0154 0.0871 0.1808
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0709 0.4635 0.6643
Schistosoma mansoni chromobox protein 0.0152 0.086 0.1218
Loa Loa (eye worm) hypothetical protein 0.0484 0.3109 0.445
Loa Loa (eye worm) choline O-acetyltransferase 0.0198 0.1171 0.1664
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0109 0.0572 0.0804
Loa Loa (eye worm) cysteine protease 0.0709 0.4635 0.6643
Loa Loa (eye worm) hypothetical protein 0.0365 0.2302 0.3291
Echinococcus granulosus cathepsin L 0.0379 0.2397 0.3426
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1054 0.6971 1
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.003 0.003 0.0043
Schistosoma mansoni cathepsin S (C01 family) 0.0154 0.0871 0.1233
Brugia malayi Cathepsin L-like precursor 0.0484 0.3109 0.4451
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Schistosoma mansoni phosphatidylserine receptor 0.0048 0.0157 0.0208
Brugia malayi jmjC domain containing protein 0.0048 0.0157 0.0211
Giardia lamblia Cathepsin B precursor 0.0154 0.0871 0.0831
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Echinococcus granulosus phd:f box containing protein 0.0048 0.0157 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0154 0.0871 0.0871
Onchocerca volvulus 0.0709 0.4635 0.9788
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0154 0.0871 0.0831
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0154 0.0871 0.0871
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Toxoplasma gondii cathepsin CPL 0.0709 0.4635 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Plasmodium vivax vivapain-1 0.0379 0.2397 0.5129
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0379 0.2397 0.3438
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0154 0.0871 0.1233
Echinococcus granulosus cathepsin L cysteine proteinase 0.0709 0.4635 0.6643
Entamoeba histolytica cysteine proteinase, putative 0.0379 0.2397 0.2397
Giardia lamblia Cysteine protease 0.0154 0.0871 0.0831
Schistosoma mansoni hypothetical protein 0.0049 0.0162 0.0214
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Loa Loa (eye worm) choline/Carnitine O-acyltransferase 0.003 0.003 0.0026
Giardia lamblia Hypothetical protein 0.0154 0.0871 0.0831
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.005 0.0171 0.0228
Loa Loa (eye worm) ctsf protein 0.0709 0.4635 0.6643
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Schistosoma mansoni choline o-acyltransferase 0.0198 0.1171 0.1664
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0379 0.2397 0.3426
Echinococcus multilocularis jumonji domain containing 1A 0.0048 0.0157 0.0208
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0733 0.4798 0.5
Plasmodium vivax vivapain-3 0.0379 0.2397 0.5129
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0048 0.0157 0.0276
Loa Loa (eye worm) hypothetical protein 0.0085 0.0407 0.0567
Loa Loa (eye worm) jmjC domain-containing protein 0.0048 0.0157 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Trypanosoma cruzi cysteine peptidase, putative 0.0709 0.4635 0.6649
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0733 0.4798 0.5
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0154 0.0871 0.0871
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0154 0.0871 0.1235
Echinococcus granulosus chromobox protein 1 0.0152 0.086 0.1218
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0379 0.2397 0.3426
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.003 0.003 0.0028
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Loa Loa (eye worm) hypothetical protein 0.0048 0.0157 0.0208
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0154 0.0871 0.1808
Plasmodium vivax serine-repeat antigen (SERA) 0.0154 0.0871 0.1808
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Echinococcus multilocularis cathepsin L 0.0154 0.0871 0.1233
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Trypanosoma cruzi choline/carnitine O-acetyltransferase, putative 0.003 0.003 0.0043
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0154 0.0871 0.0871
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.049 0.3153 0.4513
Brugia malayi cathepsin Z-like cysteine proteinase 0.0154 0.0871 0.1235
Loa Loa (eye worm) jmjC domain-containing protein 0.0183 0.1072 0.1522
Brugia malayi PHD-finger family protein 0.0051 0.0175 0.0237
Loa Loa (eye worm) heterochromatin protein 1 0.0152 0.086 0.1218
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0109 0.0572 0.0804
Leishmania major carnitine/choline acetyltransferase, putative 0.003 0.003 0.0065
Onchocerca volvulus Cathepsin L homolog 0.0709 0.4635 0.9788
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.004 0.0021
Plasmodium vivax hypothetical protein, conserved 0.015 0.0844 0.1751
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0154 0.0871 0.1808
Giardia lamblia Cysteine protease 0.0154 0.0871 0.0831
Brugia malayi cathepsin L-like precursor 0.0484 0.3109 0.4451
Giardia lamblia Hypothetical protein 0.0154 0.0871 0.0831
Toxoplasma gondii cathepsin CPC1 0.0154 0.0871 0.1808
Plasmodium falciparum serine repeat antigen 6 0.0154 0.0871 0.1808
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Loa Loa (eye worm) transcription factor SMAD2 0.0144 0.0807 0.1141
Brugia malayi Bromodomain containing protein 0.0041 0.0108 0.0139
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Giardia lamblia Encystation-specific protease 0.0154 0.0871 0.0831
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0031 0.0043 0.0028
Loa Loa (eye worm) hypothetical protein 0.0046 0.0139 0.0182
Schistosoma mansoni eyes absent homolog 0.0106 0.0551 0.0774
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0154 0.0871 0.0871
Echinococcus granulosus peregrin 0.0152 0.0862 0.122
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0154 0.0871 0.1233
Brugia malayi cathepsin Z-like cysteine proteinase 0.0154 0.0871 0.1235
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Giardia lamblia Cysteine protease 0.0154 0.0871 0.0831
Schistosoma mansoni bromodomain containing protein 0.0068 0.0289 0.0397
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Entamoeba histolytica Flap nuclease, putative 0.0031 0.0043 0.0043
Schistosoma mansoni cathepsin s 0.0225 0.1356 0.1931
Echinococcus multilocularis snurportin 1 0.033 0.2068 0.2955
Schistosoma mansoni chromobox protein 0.0152 0.086 0.1218
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Brugia malayi Choline O-acetyltransferase 0.0198 0.1171 0.1667
Brugia malayi Choline/Carnitine o-acyltransferase family protein 0.003 0.003 0.0028
Trypanosoma cruzi major cysteine proteinase, putative 0.0154 0.0871 0.1249
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0709 0.4635 0.6643
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0154 0.0871 0.1233
Plasmodium falciparum serine repeat antigen 4 0.0154 0.0871 0.1808
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0154 0.0871 0.0871
Entamoeba histolytica cysteine protease, putative 0.0709 0.4635 0.4635
Trypanosoma cruzi choline/carnitine O-acyltransferase, putative 0.003 0.003 0.0043
Brugia malayi Bromodomain containing protein 0.0152 0.0862 0.1223
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0154 0.0871 0.1808
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0154 0.0871 0.0871
Plasmodium vivax vivapain-2 0.0709 0.4635 1
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Loa Loa (eye worm) hypothetical protein 0.0076 0.0343 0.0475
Brugia malayi Bromodomain containing protein 0.008 0.0374 0.0522
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1054 0.6971 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0144 0.0807 0.1141
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.003 0.0043
Plasmodium falciparum serine repeat antigen 9 0.0154 0.0871 0.1808
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Loa Loa (eye worm) hypothetical protein 0.015 0.0844 0.1196
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0154 0.0871 0.0831
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.003 0.003 0.0043
Trypanosoma cruzi cysteine peptidase, putative 0.0709 0.4635 0.6649
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0239 0.0239
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0048 0.0157 0.0226
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0154 0.0871 0.1233
Echinococcus multilocularis cysteine protease 0.0709 0.4635 0.6643
Brugia malayi Papain family cysteine protease containing protein 0.0154 0.0871 0.1235
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.003 0.0043
Plasmodium vivax unspecified product 0.0154 0.0871 0.1808
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Schistosoma mansoni importin beta-1 0.0031 0.004 0.0039
Treponema pallidum fructose-bisphosphate aldolase 0.1501 1 0.5
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0154 0.0871 0.1233
Loa Loa (eye worm) hypothetical protein 0.0044 0.0125 0.0162
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Trichomonas vaginalis set domain proteins, putative 0.0724 0.4735 0.4735
Giardia lamblia Cathepsin B precursor 0.0432 0.2757 0.2726
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0154 0.0871 0.1808
Echinococcus granulosus cathepsin b 0.1054 0.6971 1
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0154 0.0871 0.1808
Brugia malayi SET domain containing protein 0.0028 0.0021 0.0015
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0154 0.0871 0.1808
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0709 0.4635 0.6643
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0154 0.0871 0.1808
Trypanosoma cruzi cruzipain precursor, putative 0.0225 0.1356 0.1945
Leishmania major hypothetical protein, conserved 0.0048 0.0157 0.034
Brugia malayi Choline O-acetyltransferase 0.0198 0.1171 0.1667
Loa Loa (eye worm) flap endonuclease-1 0.0031 0.0043 0.0044
Echinococcus granulosus choline O acetyltransferase 0.0198 0.1171 0.1664
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.015 0.0844 0.1196
Loa Loa (eye worm) PHD-finger family protein 0.015 0.0844 0.1196
Echinococcus multilocularis chromobox protein 1 0.0152 0.086 0.1218
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Trypanosoma cruzi cysteine proteinase, putative 0.0379 0.2397 0.3438
Plasmodium vivax unspecified product 0.0225 0.1356 0.2865
Echinococcus multilocularis cathepsin L 0.0379 0.2397 0.3426
Loa Loa (eye worm) hypothetical protein 0.0154 0.0871 0.1233
Plasmodium falciparum serine repeat antigen 1 0.0154 0.0871 0.1808
Onchocerca volvulus 0.0709 0.4635 0.9788
Onchocerca volvulus Cathepsin L homolog 0.0709 0.4635 0.9788
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Echinococcus multilocularis peregrin 0.0152 0.0862 0.122
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Trypanosoma brucei cysteine peptidase C (CPC) 0.0432 0.2757 0.5922
Loa Loa (eye worm) hypothetical protein 0.0484 0.3109 0.445
Plasmodium falciparum serine repeat antigen 5 0.0154 0.0871 0.1808
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1054 0.6971 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0048 0.0157 0.0208
Plasmodium falciparum serine repeat antigen 2 0.0154 0.0871 0.1808
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0154 0.0871 0.0831
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0154 0.0871 0.0871
Brugia malayi jmjC domain containing protein 0.0048 0.0157 0.0211
Schistosoma mansoni cathepsin C 0.0154 0.0871 0.1233
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Trypanosoma cruzi cysteine peptidase, putative 0.0225 0.1356 0.1945
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0709 0.4635 0.4635
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0154 0.0871 0.1808
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Onchocerca volvulus 0.0067 0.0283 0.0536
Plasmodium vivax JmjC domain containing protein 0.0048 0.0157 0.0256
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0049 0.0162 0.0285
Trichomonas vaginalis chromobox protein, putative 0.0152 0.086 0.086
Plasmodium vivax unspecified product 0.0379 0.2397 0.5129
Brugia malayi jmjC domain containing protein 0.0183 0.1072 0.1525
Giardia lamblia Cathepsin L precursor 0.0154 0.0871 0.0831
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0484 0.3109 0.3109
Toxoplasma gondii PHD-finger domain-containing protein 0.015 0.0844 0.1751
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0038 0.0091 0.0112
Giardia lamblia Cathepsin L-like protease 0.0154 0.0871 0.0831
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0154 0.0871 0.0871
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0109 0.0572 0.0804
Loa Loa (eye worm) hypothetical protein 0.0198 0.1171 0.1664
Trypanosoma cruzi cysteine peptidase, putative 0.0379 0.2397 0.3438
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0064 0.0263 0.036
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0048 0.0157 0.0226
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0871 0.0871
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0116 0.0617 0.0868
Brugia malayi MH2 domain containing protein 0.0144 0.0807 0.1144
Loa Loa (eye worm) hypothetical protein 0.0225 0.1356 0.1931
Echinococcus granulosus chromobox protein 1 0.0152 0.086 0.1218
Leishmania major choline/Carnitine o-acyltransferase-like protein 0.003 0.003 0.0065
Entamoeba histolytica cysteine proteinase, putative 0.0379 0.2397 0.2397
Brugia malayi Pre-SET motif family protein 0.0636 0.4139 0.5932
Schistosoma mansoni cathepsin F (C01 family) 0.0709 0.4635 0.6643
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.003 0.0043
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0031 0.0043 0.0062
Onchocerca volvulus Alhambra homolog 0.015 0.0844 0.1731
Entamoeba histolytica cysteine protease, putative 0.0154 0.0871 0.0871
Schistosoma mansoni cathepsin B (C01 family) 0.0154 0.0871 0.1233
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Loa Loa (eye worm) jmjC domain-containing protein 0.0309 0.1925 0.2748
Plasmodium falciparum serine repeat antigen 7 0.0154 0.0871 0.1808
Echinococcus granulosus jumonji domain containing protein 0.0208 0.1242 0.1767
Plasmodium vivax vivapain-2 0.0709 0.4635 1
Plasmodium falciparum JmjC domain-containing protein, putative 0.0048 0.0157 0.0256
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0379 0.2397 0.5139
Giardia lamblia Cathepsin B precursor 0.0154 0.0871 0.0831
Onchocerca volvulus Cathepsin L homolog 0.0154 0.0871 0.1786
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Schistosoma mansoni jumonji domain containing protein 0.0048 0.0157 0.0208
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.005 0.0171 0.0228
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0379 0.2397 0.5139
Brugia malayi RNA, U transporter 1 0.0088 0.0426 0.0597
Onchocerca volvulus Cathepsin F homolog 0.0709 0.4635 0.9788
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0154 0.0871 0.1808
Loa Loa (eye worm) hypothetical protein 0.0031 0.004 0.0039
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0448 0.0626
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0432 0.2757 0.5949
Echinococcus multilocularis chromobox protein 1 0.0152 0.086 0.1218
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0048 0.0157 0.0208
Leishmania major carnitine palmitoyltransferase-like protein 0.003 0.003 0.0065
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0052 0.0184 0.0247
Toxoplasma gondii PHD-finger domain-containing protein 0.0049 0.0162 0.0265
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0154 0.0871 0.1808
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0448 0.0889
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.0407 0.0407
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0709 0.4635 0.4635
Plasmodium falciparum flap endonuclease 1 0.0031 0.0043 0.0007
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0085 0.0407 0.0802
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0031 0.0043 0.0093
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0049 0.0162 0.0265
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0154 0.0871 0.1233
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0154 0.0871 0.1233
Schistosoma mansoni cathepsin F (C01 family) 0.0484 0.3109 0.445
Echinococcus granulosus lysine specific demethylase 6a 0.0048 0.0157 0.0208
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Entamoeba histolytica cysteine proteinase, putative 0.0484 0.3109 0.3109
Plasmodium falciparum serine repeat antigen 8 0.0154 0.0871 0.1808
Giardia lamblia Cathepsin B precursor 0.0154 0.0871 0.0831
Trypanosoma cruzi carnitine O-acetyltransferase, putative 0.003 0.003 0.0043
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0154 0.0871 0.1233
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0038 0.0091 0.0112
Giardia lamblia Cathepsin B precursor 0.0154 0.0871 0.0831
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Brugia malayi F/Y-rich N-terminus family protein 0.0054 0.0198 0.0269
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Echinococcus multilocularis phd:f box containing protein 0.0048 0.0157 0.0208
Loa Loa (eye worm) hypothetical protein 0.0109 0.0572 0.0804
Plasmodium vivax serine-repeat antigen (SERA) 0.0154 0.0871 0.1808
Loa Loa (eye worm) hypothetical protein 0.0106 0.0551 0.0774
Toxoplasma gondii cathepsin B 0.0432 0.2757 0.5914
Brugia malayi Papain family cysteine protease containing protein 0.0379 0.2397 0.3428
Onchocerca volvulus 0.0709 0.4635 0.9788
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0154 0.0871 0.0831
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0379 0.2397 0.2397
Echinococcus granulosus importin subunit beta 1 0.0031 0.004 0.0039
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0154 0.0871 0.0871
Brugia malayi jmjC domain containing protein 0.049 0.3153 0.4514
Leishmania major cysteine peptidase A (CPA) 0.0709 0.4635 1
Loa Loa (eye worm) carnitine O-palmitoyltransferase I isoform 0.003 0.003 0.0026
Echinococcus multilocularis cysteine protease 0.0709 0.4635 0.6643
Brugia malayi cathepsin B-like cysteine proteinase 0.1054 0.6971 1
Echinococcus multilocularis jumonji domain containing protein 0.0208 0.1242 0.1767
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0048 0.0157 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0154 0.0871 0.0871
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.1501 1 1
Echinococcus granulosus jumonji domain containing 1A 0.0048 0.0157 0.0208
Brugia malayi jmjC domain containing protein 0.0048 0.0157 0.0211
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0709 0.4635 1
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0154 0.0871 0.1808
Echinococcus multilocularis flap endonuclease 1 0.0031 0.0043 0.0044
Echinococcus multilocularis choline O acetyltransferase 0.0198 0.1171 0.1664
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0049 0.0162 0.0265
Entamoeba histolytica cysteine protease, putative 0.0379 0.2397 0.2397
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0239 0.0239
Entamoeba histolytica cysteine proteinase, putative 0.0379 0.2397 0.2397
Brugia malayi fibroinase precursor 0.0154 0.0871 0.1235
Entamoeba histolytica cysteine proteinase, putative 0.0709 0.4635 0.4635
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0709 0.4635 0.4635
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0092 0.0451 0.0895
Brugia malayi Cathepsin L-like cysteine proteinase 0.0484 0.3109 0.4451
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0048 0.0157 0.0256
Giardia lamblia Cysteine protease 0.0154 0.0871 0.0831
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Schistosoma mansoni flap endonuclease-1 0.0028 0.0023 0.0015
Echinococcus granulosus cathepsin L cysteine protease 0.0379 0.2397 0.3426
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Echinococcus multilocularis cathepsin b 0.1054 0.6971 1
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Echinococcus multilocularis importin subunit beta 1 0.0031 0.004 0.0039
Trypanosoma cruzi carnitine/choline acetyltransferase, putative 0.003 0.003 0.0043
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0049 0.0162 0.0285
Echinococcus multilocularis PHD finger protein rhinoceros 0.015 0.0844 0.1196
Echinococcus granulosus PHD finger protein rhinoceros 0.015 0.0844 0.1196
Schistosoma mansoni choline o-acyltransferase 0.003 0.003 0.0026
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0154 0.0871 0.0871
Brugia malayi cathepsin F-like cysteine proteinase 0.0154 0.0871 0.1235
Brugia malayi Cathepsin L-like precursor 0.0709 0.4635 0.6644
Leishmania major cathepsin L-like protease 0.0709 0.4635 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0183 0.1072 0.1522
Brugia malayi cathepsin L-like cysteine proteinase 0.0154 0.0871 0.1235
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0636 0.4139 0.593
Loa Loa (eye worm) cathepsin B 0.0432 0.2757 0.3945
Brugia malayi Cathepsin L-like precursor 0.0225 0.1356 0.1933
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1054 0.6971 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0432 0.2757 0.3955
Giardia lamblia Fructose-bisphosphate aldolase 0.1501 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0432 0.2757 0.2757
Schistosoma mansoni jumonji/arid domain-containing protein 0.0183 0.1072 0.1522
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0154 0.0871 0.0871
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0709 0.4635 1
Schistosoma mansoni jumonji domain containing protein 0.039 0.247 0.3531
Echinococcus multilocularis carnitine O palmitoyltransferase 2 0.003 0.003 0.0026
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.033 0.2068 0.2955
Trypanosoma cruzi cysteine protease, putative 0.0379 0.2397 0.3438
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0709 0.4635 0.6643
Echinococcus multilocularis cathepsin L cysteine protease 0.0709 0.4635 0.6643

Activities

Activity type Activity value Assay description Source Reference
I50 (binding) = 0.0000035 M Inhibition of Choline Acetyltransferase ChEMBL. 7932536
IC50 (binding) = 0.0000035 M Inhibition of Choline Acetyltransferase ChEMBL. 7932536

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

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