Detailed information for compound 176440

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 618.629 | Formula: C30H38N2O12
  • H donors: 5 H acceptors: 8 LogP: 4.19 Rotable bonds: 20
    Rule of 5 violations (Lipinski): 2
  • SMILES: COC(=O)c1c(OCCCCNC(=O)[C@H](Cc2ccc(c(c2)C(=O)O)OC(C(=O)O)C)NC(=O)OC(C)(C)C)cccc1O
  • InChi: 1S/C30H38N2O12/c1-17(26(35)36)43-22-12-11-18(15-19(22)27(37)38)16-20(32-29(40)44-30(2,3)4)25(34)31-13-6-7-14-42-23-10-8-9-21(33)24(23)28(39)41-5/h8-12,15,17,20,33H,6-7,13-14,16H2,1-5H3,(H,31,34)(H,32,40)(H,35,36)(H,37,38)/t17?,20-/m0/s1
  • InChiKey: MSBXLJNHWCDEEW-OZBJMMHXSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major glucose transporter, lmgt1 0.001 0.0047 0.003
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Schistosoma mansoni cathepsin S (C01 family) 0.0091 0.1524 0.1847
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.018 0.0196
Giardia lamblia Hexose transporter 0.001 0.0047 0.0082
Trypanosoma cruzi hexose transporter, putative 0.001 0.0047 0.003
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Plasmodium vivax unspecified product 0.0149 0.2563 0.2546
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0091 0.1524 0.1524
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Trichomonas vaginalis hypothetical protein 0.0559 1 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Onchocerca volvulus 0.0011 0.0068 0.0025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus granulosus lamin 0.0012 0.0088 0.0082
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.018 0.0196
Trypanosoma cruzi sugar transporter, putative 0.001 0.0047 0.003
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.001 0.0047 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Giardia lamblia Cysteine protease 0.0091 0.1524 0.5023
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0423 0.7536 0.9235
Echinococcus multilocularis hypothetical protein 0.0011 0.0068 0.0058
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0047 0.003
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Schistosoma mansoni sugar transporter 0.001 0.0047 0.0033
Echinococcus multilocularis solute carrier family 22 0.001 0.0047 0.0033
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0011 0.0068 0.0058
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.519 0.6352
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.024 0.4213 0.5152
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0458 0.8158 0.8158
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0038 0.0559 0.0659
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0458 0.8158 0.8158
Leishmania major cysteine peptidase A (CPA) 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0536 0.0631
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Onchocerca volvulus 0.0011 0.0068 0.0025
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Echinococcus granulosus solute carrier family 22 0.001 0.0047 0.0033
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0091 0.1524 0.1847
Brugia malayi Papain family cysteine protease containing protein 0.0091 0.1524 0.1845
Loa Loa (eye worm) hypothetical protein 0.0357 0.6331 0.7754
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0047 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Schistosoma mansoni cathepsin F (C01 family) 0.0309 0.5469 0.6695
Schistosoma mansoni hypothetical protein 0.0017 0.018 0.0196
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0458 0.8158 0.8154
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0011 0.0068 0.0055
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0038 0.0559 0.0538
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Loa Loa (eye worm) cathepsin B 0.0173 0.3011 0.3672
Entamoeba histolytica cysteine proteinase, putative 0.024 0.4213 0.5151
Trichomonas vaginalis glucose transporter, putative 0.001 0.0047 0.0047
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0123 0.0123
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0038 0.0559 0.0662
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Echinococcus multilocularis cpg binding protein 0.0033 0.0463 0.0544
Loa Loa (eye worm) hypothetical protein 0.0017 0.018 0.0193
Plasmodium falciparum serine repeat antigen 3 0.0091 0.1524 0.1504
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Schistosoma mansoni cathepsin F (C01 family) 0.0458 0.8158 1
Plasmodium vivax vivapain-2 0.0458 0.8158 0.8154
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0011 0.0068 0.0055
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0309 0.5469 0.6694
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0011 0.0068 0.0058
Plasmodium vivax sugar transporter, putative 0.001 0.0047 0.0025
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.024 0.4213 0.5152
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0038 0.0559 0.0662
Onchocerca volvulus 0.0011 0.0068 0.0025
Trypanosoma cruzi cysteine peptidase, putative 0.0458 0.8158 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0053 0.0037
Brugia malayi Intermediate filament tail domain containing protein 0.0012 0.0088 0.008
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0432 0.0503
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Mycobacterium ulcerans sugar transporter 0.001 0.0047 0.0025
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Brugia malayi intermediate filament protein 0.0012 0.0088 0.008
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0621 0.0735
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.1524 0.1524
Schistosoma mansoni glucose transport protein 0.001 0.0047 0.0033
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0038 0.0559 0.0659
Trypanosoma cruzi glucose transporter, putative 0.001 0.0047 0.003
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0559 1 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus granulosus cathepsin l1 0.0458 0.8158 1
Brugia malayi hypothetical protein 0.001 0.0047 0.003
Brugia malayi Pre-SET motif family protein 0.0014 0.0123 0.0123
Giardia lamblia Cathepsin B precursor 0.0091 0.1524 0.5023
Giardia lamblia Cathepsin L-like protease 0.0091 0.1524 0.5023
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) major facilitator superfamily transporter 0.001 0.0047 0.003
Plasmodium falciparum serine repeat antigen 2 0.0091 0.1524 0.1504
Giardia lamblia Cathepsin B precursor 0.0091 0.1524 0.5023
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0038 0.0559 0.0538
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0091 0.1524 0.1504
Schistosoma mansoni cathepsin C 0.0091 0.1524 0.1847
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.5469 0.5469
Trypanosoma cruzi hexose transporter, putative 0.001 0.0047 0.003
Trypanosoma cruzi cysteine peptidase, putative 0.024 0.4213 0.5151
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0011 0.0068 0.0058
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0038 0.0559 0.0538
Onchocerca volvulus 0.0011 0.0068 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0014 0.0123 0.01
Onchocerca volvulus 0.0105 0.1766 0.2119
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0011 0.0068 0.0058
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0047 0.003
Giardia lamblia Hypothetical protein 0.0091 0.1524 0.5023
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Toxoplasma gondii cathepsin B 0.0173 0.3011 0.2995
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0091 0.1524 0.1524
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0458 0.8158 1
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0011 0.0068 0.0058
Giardia lamblia Cysteine protease 0.0091 0.1524 0.5023
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1524 0.1847
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0173 0.3011 0.3674
Onchocerca volvulus 0.0011 0.0068 0.0025
Brugia malayi cathepsin F-like cysteine proteinase 0.0149 0.2563 0.3123
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Echinococcus granulosus intermediate filament protein 0.0012 0.0088 0.0082
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni protein tyrosine phosphatase 0.0011 0.0068 0.0058
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0014 0.0123 0.0125
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0091 0.1524 0.1504
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Echinococcus multilocularis 0.0011 0.0068 0.0058
Onchocerca volvulus 0.0038 0.0559 0.0631
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Schistosoma mansoni sugar transporter 0.001 0.0047 0.0033
Trichomonas vaginalis sugar transport protein, putative 0.001 0.0047 0.0047
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0011 0.0068 0.0055
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0091 0.1524 0.1504
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0038 0.0559 0.0538
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0149 0.2563 0.3123
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0559 1 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Mycobacterium tuberculosis Possible oxidoreductase 0.0038 0.0559 0.0538
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Brugia malayi Pre-SET motif family protein 0.0092 0.1538 0.1862
Brugia malayi hypothetical protein 0.0011 0.0068 0.0055
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Trypanosoma cruzi major cysteine proteinase, putative 0.0091 0.1524 0.1845
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0038 0.0559 0.0659
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Leishmania major oxidoreductase-like protein 0.0038 0.0559 0.0659
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0038 0.0559 0.0659
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0091 0.1524 0.1524
Brugia malayi hypothetical protein 0.0011 0.0068 0.0055
Trypanosoma cruzi cysteine peptidase, putative 0.0458 0.8158 1
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Onchocerca volvulus 0.0011 0.0068 0.0025
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0038 0.0559 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Echinococcus multilocularis cathepsin L cysteine protease 0.0458 0.8158 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0091 0.1524 0.1845
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0091 0.1524 0.1845
Onchocerca volvulus 4.1 G protein, putative homolog 0.0011 0.0068 0.0025
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.018 0.0196
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Plasmodium falciparum enoyl-acyl carrier reductase 0.0559 1 1
Echinococcus granulosus lamin dm0 0.0012 0.0088 0.0082
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0038 0.0559 0.0659
Loa Loa (eye worm) hypothetical protein 0.0012 0.0084 0.0075
Trypanosoma cruzi cysteine proteinase, putative 0.024 0.4213 0.5151
Echinococcus granulosus cathepsin L 0.0091 0.1524 0.1847
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.001 0.0047 0.0025
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0091 0.1524 0.5023
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Leishmania major mitochondrial DNA polymerase beta 0.0294 0.519 0.6352
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Brugia malayi cathepsin L-like precursor 0.0309 0.5469 0.6694
Plasmodium falciparum serine repeat antigen 5 0.0091 0.1524 0.1504
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0038 0.0559 0.0538
Giardia lamblia Sugar-proton symporter 0.001 0.0047 0.0082
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Onchocerca volvulus Cathepsin L homolog 0.0091 0.1524 0.182
Giardia lamblia Cathepsin B precursor 0.0173 0.3011 1
Onchocerca volvulus 0.0031 0.0432 0.0474
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus granulosus protein tyrosine phosphatase n9 0.0011 0.0068 0.0058
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Entamoeba histolytica cysteine proteinase, putative 0.024 0.4213 0.5151
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Loa Loa (eye worm) hypothetical protein 0.0149 0.2563 0.3123
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Echinococcus multilocularis cathepsin b 0.0357 0.6331 0.7755
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.018 0.0193
Onchocerca volvulus 0.0011 0.0068 0.0025
Echinococcus multilocularis GPCR, family 2 0.0017 0.018 0.0196
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0038 0.0559 0.0538
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.018 0.0193
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trypanosoma brucei protein tyrosine phosphatase 1 0.0011 0.0068 0.0055
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1524 0.1847
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Onchocerca volvulus 0.0011 0.0068 0.0025
Brugia malayi Papain family cysteine protease containing protein 0.024 0.4213 0.5151
Echinococcus multilocularis cathepsin b 0.0357 0.6331 0.7755
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0038 0.0559 0.0538
Giardia lamblia Encystation-specific protease 0.0091 0.1524 0.5023
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Brugia malayi Papain family cysteine protease containing protein 0.024 0.4213 0.5151
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0011 0.0068 0.0058
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0309 0.5469 0.6694
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0173 0.3011 0.3011
Echinococcus multilocularis cysteine protease 0.0458 0.8158 1
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0011 0.0068 0.0058
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0011 0.0068 0.0058
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0621 0.0735
Plasmodium vivax unspecified product 0.0091 0.1524 0.1504
Toxoplasma gondii cathepsin CPL 0.0458 0.8158 0.8154
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.6331 0.7755
Schistosoma mansoni cathepsin B (C01 family) 0.0091 0.1524 0.1847
Onchocerca volvulus 0.0014 0.0123 0.0093
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Echinococcus granulosus cathepsin b 0.0357 0.6331 0.7755
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0091 0.1524 0.1504
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0458 0.8158 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0014 0.0123 0.0125
Trichomonas vaginalis glucose transporter, putative 0.001 0.0047 0.0047
Echinococcus granulosus cathepsin l cysteine peptidase 0.0458 0.8158 1
Onchocerca volvulus 0.0458 0.8158 1
Mycobacterium tuberculosis Probable oxidoreductase 0.0038 0.0559 0.0538
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Brugia malayi Papain family cysteine protease containing protein 0.0458 0.8158 1
Echinococcus granulosus cathepsin b 0.0357 0.6331 0.7755
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0011 0.0068 0.0058
Trichomonas vaginalis ap endonuclease, putative 0.0008 0.0023 0.0023
Onchocerca volvulus 0.0011 0.0068 0.0025
Giardia lamblia Cathepsin L-like protease 0.0091 0.1524 0.5023
Plasmodium vivax hexose transporter 0.001 0.0047 0.0025
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0091 0.1524 0.1845
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0047 0.003
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0423 0.7536 0.9235
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Leishmania major glucose transporter, lmgt2 0.001 0.0047 0.003
Onchocerca volvulus 0.0458 0.8158 1
Schistosoma mansoni sugar transporter 0.001 0.0047 0.0033
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Onchocerca volvulus 0.0012 0.0088 0.005
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0055 0.0042
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Loa Loa (eye worm) histone methyltransferase 0.001 0.0055 0.0039
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.001 0.0047 0.0025
Schistosoma mansoni cathepsin F (C01 family) 0.0458 0.8158 1
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0054 0.0842 0.1007
Plasmodium vivax vivapain-3 0.024 0.4213 0.42
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Mycobacterium tuberculosis Possible oxidoreductase 0.0038 0.0559 0.0538
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Brugia malayi Cathepsin L-like cysteine proteinase 0.0309 0.5469 0.6694
Trypanosoma cruzi cysteine protease, putative 0.024 0.4213 0.5151
Schistosoma mansoni dihydropteridine reductase 0.0038 0.0559 0.0662
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.001 0.0051 0.0035
Trypanosoma cruzi cysteine peptidase, putative 0.0149 0.2563 0.3123
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Onchocerca volvulus 0.0012 0.0088 0.005
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0139 0.239 0.2909
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0038 0.0559 0.0659
Leishmania major tyrosine specific protein phosphatase, putative 0.0011 0.0068 0.0055
Echinococcus multilocularis cysteine protease 0.0458 0.8158 1
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Brugia malayi Protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Entamoeba histolytica cysteine proteinase 2 0.024 0.4213 0.5151
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Giardia lamblia Protein tyrosine phosphatase 0.0011 0.0068 0.0151
Trypanosoma cruzi cruzipain precursor, putative 0.0458 0.8158 1
Echinococcus granulosus cathepsin l1 0.0309 0.5469 0.6695
Plasmodium falciparum hexose transporter 0.001 0.0047 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Brugia malayi Protein-tyrosine phosphatase 1 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Brugia malayi hypothetical protein 0.0011 0.0068 0.0055
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Giardia lamblia Cathepsin B precursor 0.0173 0.3011 1
Trypanosoma cruzi cysteine proteinase, putative 0.024 0.4213 0.5151
Trypanosoma brucei THT1 - hexose transporter, putative 0.001 0.0047 0.003
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0091 0.1524 0.1504
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Schistosoma mansoni glucose transport protein 0.001 0.0047 0.0033
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0038 0.0559 0.0538
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0038 0.0559 0.0538
Echinococcus granulosus solute carrier family 22 0.001 0.0047 0.0033
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Plasmodium falciparum cysteine proteinase falcipain 3 0.0458 0.8158 0.8154
Schistosoma mansoni cathepsin s 0.0149 0.2563 0.3124
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Plasmodium vivax unspecified product 0.024 0.4213 0.42
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0842 0.1007
Entamoeba histolytica cysteine proteinase, putative 0.0458 0.8158 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Toxoplasma gondii cathepsin CPC2 0.0091 0.1524 0.1504
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0038 0.0559 0.0538
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0091 0.1524 0.1847
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Plasmodium vivax SET domain protein, putative 0.0014 0.0123 0.01
Plasmodium vivax vivapain-2 0.0458 0.8158 0.8154
Mycobacterium tuberculosis Conserved hypothetical protein 0.0155 0.2674 0.2657
Onchocerca volvulus 0.0458 0.8158 1
Schistosoma mansoni protein tyrosine phosphatase 0.0011 0.0068 0.0058
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0423 0.7536 0.9235
Toxoplasma gondii histone lysine methyltransferase SET1 0.0059 0.094 0.0919
Onchocerca volvulus 0.0309 0.5469 0.6684
Trypanosoma brucei glucose transporter 1E 0.001 0.0047 0.003
Loa Loa (eye worm) oxidoreductase 0.0038 0.0559 0.0659
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0011 0.0068 0.0055
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0011 0.0068 0.0058
Schistosoma mansoni protein tyrosine phosphatase 0.0011 0.0068 0.0058
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Trypanosoma brucei glucose transporter 2A 0.001 0.0047 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Echinococcus multilocularis cathepsin L cysteine protease 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Onchocerca volvulus 0.0458 0.8158 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0423 0.7536 0.9235
Mycobacterium ulcerans hypothetical protein 0.0155 0.2674 0.2657
Onchocerca volvulus 0.0458 0.8158 1
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0011 0.0068 0.0058
Entamoeba histolytica cysteine proteinase 1, putative 0.024 0.4213 0.5151
Echinococcus granulosus solute carrier family 22 0.001 0.0047 0.0033
Leishmania major glucose transporter/membrane transporter D2, putative 0.001 0.0047 0.003
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0008 0.0023 0.0002
Trypanosoma cruzi cysteine peptidase, putative 0.0458 0.8158 1
Plasmodium falciparum serine repeat antigen 4 0.0091 0.1524 0.1504
Brugia malayi major facilitator superfamily protein 0.001 0.0047 0.003
Trichomonas vaginalis ap endonuclease, putative 0.0008 0.0023 0.0023
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0011 0.0068 0.0058
Plasmodium falciparum serine repeat antigen 9 0.0091 0.1524 0.1504
Onchocerca volvulus 0.0458 0.8158 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Brugia malayi cathepsin L-like cysteine proteinase 0.0091 0.1524 0.1845
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0559 1 1
Brugia malayi Sugar transporter family protein 0.001 0.0047 0.003
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0014 0.0123 0.0125
Echinococcus multilocularis lamin 0.0012 0.0088 0.0082
Entamoeba histolytica cysteine protease, putative 0.0091 0.1524 0.1845
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Toxoplasma gondii facilitative glucose transporter GT1 0.001 0.0047 0.0025
Loa Loa (eye worm) hypothetical protein 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0309 0.5469 0.6694
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.1524 0.1524
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Schistosoma mansoni pcd6 interacting protein-related 0.0011 0.0068 0.0058
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Plasmodium falciparum serine repeat antigen 6 0.0091 0.1524 0.1504
Schistosoma mansoni glucose transport protein 0.001 0.0047 0.0033
Loa Loa (eye worm) cysteine protease 0.0458 0.8158 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0013 0.0102 0.0099
Leishmania major glucose transporter, lmgt3 0.001 0.0047 0.003
Plasmodium vivax serine-repeat antigen (SERA) 0.0091 0.1524 0.1504
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0011 0.0068 0.0058
Brugia malayi CXXC zinc finger family protein 0.0031 0.0432 0.0503
Loa Loa (eye worm) intermediate filament protein 0.0012 0.0088 0.008
Entamoeba histolytica hypothetical protein 0.0091 0.1524 0.1845
Giardia lamblia Cysteine protease 0.0091 0.1524 0.5023
Brugia malayi hypothetical protein 0.0011 0.0068 0.0055
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.024 0.4213 0.5152
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0011 0.0068 0.0058
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Brugia malayi Papain family cysteine protease containing protein 0.0091 0.1524 0.1845
Brugia malayi Protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0038 0.0559 0.0659
Brugia malayi Latrophilin receptor protein 2 0.0017 0.018 0.0193
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Leishmania major pteridine reductase 1 0.0038 0.0559 0.0659
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.6331 0.7755
Echinococcus multilocularis Sugar transporter ERD6 protein 0.001 0.0047 0.0033
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Brugia malayi hypothetical protein 0.001 0.0047 0.003
Echinococcus multilocularis cathepsin L 0.024 0.4213 0.5152
Brugia malayi cathepsin B-like cysteine proteinase 0.0357 0.6331 0.7754
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Brugia malayi Major Facilitator Superfamily protein 0.001 0.0047 0.003
Trypanosoma brucei oxidoreductase-like protein 0.0038 0.0559 0.0659
Toxoplasma gondii cathepsin CPC1 0.0091 0.1524 0.1504
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0357 0.6331 0.7755
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Plasmodium vivax vivapain-1 0.024 0.4213 0.42
Giardia lamblia Hypothetical protein 0.0091 0.1524 0.5023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0621 0.0735
Brugia malayi Cathepsin L-like precursor 0.0149 0.2563 0.3123
Onchocerca volvulus 0.0011 0.0068 0.0025
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Mycobacterium ulcerans oxidoreductase 0.0038 0.0559 0.0538
Echinococcus multilocularis solute carrier family 22 0.001 0.0047 0.0033
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0091 0.1524 0.1524
Schistosoma mansoni sugar transporter 0.001 0.0047 0.0033
Schistosoma mansoni cpg binding protein 0.0031 0.0432 0.0505
Schistosoma mansoni cpg binding protein 0.0033 0.0463 0.0544
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.1524 0.1524
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.001 0.0047 0.003
Echinococcus granulosus cysteine protease 0.024 0.4213 0.5152
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Brugia malayi Sugar transporter family protein 0.001 0.0047 0.003
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0173 0.3011 0.3672
Entamoeba histolytica cysteine protease, putative 0.0458 0.8158 1
Onchocerca volvulus 0.0091 0.1524 0.182
Schistosoma mansoni intermediate filament proteins 0.0012 0.0088 0.0082
Toxoplasma gondii preprocathepsin c precursor, putative 0.0091 0.1524 0.1504
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Echinococcus granulosus GPCR family 2 0.0017 0.018 0.0196
Onchocerca volvulus 0.0011 0.0068 0.0025
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Echinococcus granulosus synaptic vesicle 2 protein 0.001 0.0051 0.0037
Brugia malayi Cathepsin L-like precursor 0.0309 0.5469 0.6694
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1524 0.1847
Onchocerca volvulus 0.0011 0.0068 0.0025
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Trichomonas vaginalis glucose transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0091 0.1524 0.1847
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.024 0.4213 0.5151
Onchocerca volvulus Cathepsin F homolog 0.0458 0.8158 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0091 0.1524 0.5023
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0014 0.0123 0.0125
Trypanosoma brucei cysteine peptidase C (CPC) 0.0173 0.3011 0.3672
Schistosoma mansoni hypothetical protein 0.0037 0.0536 0.0633
Echinococcus multilocularis synaptic vesicle 2 protein 0.001 0.0051 0.0037
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0011 0.0068 0.0058
Loa Loa (eye worm) hypothetical protein 0.0012 0.0088 0.008
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Echinococcus multilocularis cathepsin L 0.0091 0.1524 0.1847
Leishmania major myo-inositol/proton symporter (MIT) 0.001 0.0047 0.003
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0038 0.0559 0.0538
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Trypanosoma brucei sugar transporter, putative 0.001 0.0047 0.003
Trichomonas vaginalis myo-inositol transporter, putative 0.001 0.0047 0.0047
Onchocerca volvulus 0.0011 0.0068 0.0025
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0091 0.1524 0.1504
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Onchocerca volvulus 0.0011 0.0068 0.0025
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Plasmodium falciparum serine repeat antigen 1 0.0091 0.1524 0.1504
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0091 0.1524 0.5023
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0008 0.0023 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0011 0.0068 0.0055
Brugia malayi cathepsin Z-like cysteine proteinase 0.0091 0.1524 0.1845
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.018 0.0196
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0091 0.1524 0.1524
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.4213 0.5151
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0011 0.0068 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0038 0.0559 0.0538
Entamoeba histolytica cysteine proteinase, putative 0.0309 0.5469 0.6694
Onchocerca volvulus Cathepsin L homolog 0.0458 0.8158 1
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.1066 0.1284
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0011 0.0068 0.0058
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0423 0.7536 0.9235
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0559 1 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0091 0.1524 0.1504
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0458 0.8158 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0011 0.0068 0.0055
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.1524 0.1524
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0536 0.0631
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0038 0.0559 0.0538
Schistosoma mansoni ap endonuclease 0.0008 0.0023 0.0002
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Giardia lamblia Cathepsin B precursor 0.0091 0.1524 0.5023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Onchocerca volvulus 0.0011 0.0068 0.0025
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0011 0.0068 0.0058
Brugia malayi Papain family cysteine protease containing protein 0.0091 0.1524 0.1845
Echinococcus granulosus cathepsin L cysteine protease 0.024 0.4213 0.5152
Entamoeba histolytica cysteine proteinase, putative 0.0458 0.8158 1
Loa Loa (eye worm) ctsf protein 0.0458 0.8158 1
Brugia malayi major facilitator superfamily protein 0.001 0.0047 0.003
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.001 0.0047 0.0033
Giardia lamblia Cathepsin B precursor 0.0091 0.1524 0.5023
Trichomonas vaginalis pten, drome, putative 0.0011 0.0068 0.0068
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.001 0.0051 0.0028
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0011 0.0068 0.0058
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0011 0.0068 0.0058
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Brugia malayi cathepsin Z-like cysteine proteinase 0.0091 0.1524 0.1845
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.001 0.0047 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0091 0.1524 0.1524
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0091 0.1524 0.1524
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Toxoplasma gondii sugar transporter ST2 0.001 0.0047 0.0025
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1524 0.1847
Treponema pallidum exodeoxyribonuclease (exoA) 0.0008 0.0023 0.5
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0055 0.0042
Plasmodium vivax serine-repeat antigen (SERA) 0.0091 0.1524 0.1504
Trypanosoma cruzi hexose transporter 0.001 0.0047 0.003
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0091 0.1524 0.1504
Brugia malayi fibroinase precursor 0.0091 0.1524 0.1845
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0091 0.1524 0.1845
Brugia malayi cathepsin L precursor 0.0091 0.1524 0.1845
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0011 0.0068 0.0055
Onchocerca volvulus Cathepsin L homolog 0.0458 0.8158 1
Mycobacterium ulcerans integral membrane transport protein 0.001 0.0047 0.0025
Onchocerca volvulus 0.0038 0.0559 0.0631
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0038 0.0559 0.0659
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.4213 0.4213
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Giardia lamblia Cysteine protease 0.0091 0.1524 0.5023
Loa Loa (eye worm) hypothetical protein 0.0038 0.0559 0.0659
Trichomonas vaginalis conserved hypothetical protein 0.001 0.0047 0.0047
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0842 0.1007
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0091 0.1524 0.1524
Giardia lamblia Cathepsin L precursor 0.0091 0.1524 0.5023
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0091 0.1524 0.1524
Onchocerca volvulus 0.0458 0.8158 1
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0011 0.0068 0.0058
Echinococcus granulosus cpg binding protein 0.0033 0.0463 0.0544
Trypanosoma cruzi hexose transporter, putative 0.001 0.0047 0.003
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0091 0.1524 0.5023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0559 1 1
Schistosoma mansoni hypothetical protein 0.0017 0.018 0.0196
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Giardia lamblia Cathepsin B precursor 0.0091 0.1524 0.5023
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0091 0.1524 0.1845
Plasmodium falciparum serine repeat antigen 8 0.0091 0.1524 0.1504
Toxoplasma gondii transporter, major facilitator family protein 0.001 0.0047 0.0025
Brugia malayi Cathepsin L-like precursor 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0091 0.1524 0.1524
Brugia malayi hypothetical protein 0.001 0.0047 0.003
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0038 0.0559 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0011 0.0068 0.0058
Toxoplasma gondii sugar transporter ST3 0.001 0.0047 0.0025
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Schistosoma mansoni ap endonuclease 0.0008 0.0023 0.0002
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0173 0.3011 0.3672
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0014 0.0123 0.0125
Onchocerca volvulus 0.0011 0.0068 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.024 0.4213 0.4213
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0012 0.0088 0.008
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0091 0.1524 0.1845
Plasmodium falciparum serine repeat antigen 7 0.0091 0.1524 0.1504
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0309 0.5469 0.5469
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Echinococcus granulosus solute carrier family 22 0.001 0.0047 0.0033
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0149 0.2563 0.3123
Loa Loa (eye worm) sugar transporter 0.001 0.0047 0.003
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) fibroinase 0.0458 0.8158 1
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.001 0.0047 0.0025
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0091 0.1524 0.1504
Echinococcus granulosus Sugar transporter ERD6 protein 0.001 0.0047 0.0033
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Onchocerca volvulus 0.0011 0.0068 0.0025
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Echinococcus granulosus cathepsin L 0.024 0.4213 0.5152
Onchocerca volvulus 0.0011 0.0068 0.0025
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0038 0.0559 0.0538
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0011 0.0068 0.0058
Schistosoma mansoni glucose transporter 0.001 0.0047 0.0033
Toxoplasma gondii sugar transporter ST1 0.001 0.0047 0.0025
Brugia malayi hypothetical protein 0.0011 0.0068 0.0055
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0091 0.1524 0.1504
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.024 0.4213 0.5151
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0014 0.0123 0.0125
Echinococcus granulosus cathepsin L cysteine proteinase 0.0458 0.8158 1
Schistosoma mansoni lamin 0.0012 0.0088 0.0082
Plasmodium falciparum cysteine proteinase falcipain 1 0.024 0.4213 0.42
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0357 0.6331 0.7755
Echinococcus multilocularis lamin dm0 0.0012 0.0088 0.0082
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0011 0.0068 0.0055
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0149 0.2563 0.3123
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Onchocerca volvulus 0.0011 0.0068 0.0025
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0559 1 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0038 0.0559 0.0538
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Onchocerca volvulus 0.0011 0.0068 0.0025
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0091 0.1524 0.1847
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0357 0.6331 0.7754
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0785 0.0936
Mycobacterium ulcerans short chain dehydrogenase 0.0038 0.0559 0.0538
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0038 0.0559 0.0662
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trypanosoma brucei pteridine reductase 1 0.0038 0.0559 0.0659
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0621 0.0735
Schistosoma mansoni cpg binding protein 0.0033 0.0463 0.0544
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0011 0.0068 0.0058
Trypanosoma cruzi hexose transporter, putative 0.001 0.0047 0.003
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.001 0.0047 0.0033
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0091 0.1524 0.1504
Echinococcus multilocularis solute carrier family 22 0.001 0.0047 0.0033
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0011 0.0068 0.0055
Brugia malayi Sugar transporter family protein 0.001 0.0047 0.003
Echinococcus multilocularis solute carrier family 22 0.001 0.0047 0.0033
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.001 0.0047 0.0025
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0091 0.1524 0.1845
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.239 0.2909
Trypanosoma cruzi cysteine peptidase, putative 0.0458 0.8158 1
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0294 0.519 0.6352
Trypanosoma cruzi major cysteine proteinase, putative 0.0091 0.1524 0.1845
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Loa Loa (eye worm) hypothetical protein 0.0149 0.2563 0.3123
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0458 0.8158 0.8154
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Leishmania major cathepsin L-like protease 0.0458 0.8158 1
Trichomonas vaginalis set domain proteins, putative 0.0105 0.1766 0.1766
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0038 0.0559 0.0538
Leishmania major hypothetical protein, conserved 0.001 0.0047 0.003
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0139 0.239 0.2909
Trichomonas vaginalis sugar transporter, putative 0.001 0.0047 0.0047
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Loa Loa (eye worm) retinol dehydrogenase 12 0.0038 0.0559 0.0659
Loa Loa (eye worm) major facilitator superfamily transporter 0.001 0.0047 0.003
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Onchocerca volvulus 0.0011 0.0068 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0038 0.0559 0.0538
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0458 0.8158 0.8158
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Loa Loa (eye worm) protein tyrosine phosphatase 0.0011 0.0068 0.0055
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0014 0.0123 0.0125
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0038 0.0559 0.0659
Schistosoma mansoni hypothetical protein 0.0017 0.018 0.0196
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0038 0.0559 0.0659
Loa Loa (eye worm) hypothetical protein 0.001 0.0047 0.003
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0091 0.1524 0.1847
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0091 0.1524 0.1504
Giardia lamblia Cathepsin B precursor 0.0173 0.3011 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0842 0.1007
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0011 0.0068 0.0055
Schistosoma mansoni lamin 0.0012 0.0088 0.0082
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0091 0.1524 0.1504
Schistosoma mansoni hypothetical protein 0.001 0.0047 0.0033
Echinococcus multilocularis musashi 0.0012 0.0088 0.0082
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0458 0.8158 1
Loa Loa (eye worm) hypothetical protein 0.0091 0.1524 0.1845
Trypanosoma brucei glucose transporter, putative 0.001 0.0047 0.003
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0011 0.0068 0.0058
Onchocerca volvulus 0.0011 0.0068 0.0025
Entamoeba histolytica cysteine proteinase, putative 0.024 0.4213 0.5151
Loa Loa (eye worm) hypothetical protein 0.0309 0.5469 0.6694
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0011 0.0068 0.0058
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0038 0.0559 0.0659
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0294 0.519 0.6352
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0011 0.0068 0.0055
Entamoeba histolytica cysteine protease, putative 0.024 0.4213 0.5151
Schistosoma mansoni hypothetical protein 0.0017 0.018 0.0196
Entamoeba histolytica cysteine proteinase, putative 0.024 0.4213 0.5151
Toxoplasma gondii hypothetical protein 0.0047 0.0731 0.071
Loa Loa (eye worm) sugar transporter 0.001 0.0047 0.003
Trypanosoma cruzi cruzipain precursor, putative 0.0149 0.2563 0.3123
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0011 0.0068 0.0058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0458 0.8158 0.8158
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0092 0.1538 0.1862
Brugia malayi Cathepsin L-like precursor 0.0309 0.5469 0.6694
Onchocerca volvulus 0.0011 0.0068 0.0025

Activities

Activity type Activity value Assay description Source Reference
Ki (binding) = 4.31 Inhibition of PTP1B (unknown origin) LITERATURE. No reference
Ki (binding) = 48.6 uM Inhibition of Protein-tyrosine phosphatase 1B (PTP1B) ChEMBL. 12951078
Ki (binding) = 48.6 uM Inhibition of Protein-tyrosine phosphatase 1B (PTP1B) ChEMBL. 12951078
Ki (binding) = 48.6 uM Inhibition of PTP1B (unknown origin) LITERATURE. No reference
Ki (binding) = 273 uM Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP) ChEMBL. 12951078
Ki (binding) = 273 uM Inhibition of T-cell Protein Tyrosine Phosphatase (TCPTP) ChEMBL. 12951078
Ratio (binding) = 5.6 Ratio for inhibitory potency against Protein Tyrosine Phosphatase 1b to that of T-cell Protein Tyrosine Phosphatase ChEMBL. 12951078

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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