Detailed information for compound 1795527

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 595.036 | Formula: C24H23ClN12O3S
  • H donors: 5 H acceptors: 7 LogP: 3.54 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: NC(=O)NNc1nc(Nc2ccc(cc2)[N+](=O)[O-])nc(n1)N1CCN(CC1)C(=S)Nc1ccnc2c1ccc(c2)Cl
  • InChi: 1S/C24H23ClN12O3S/c25-14-1-6-17-18(7-8-27-19(17)13-14)29-24(41)36-11-9-35(10-12-36)23-31-21(30-22(32-23)34-33-20(26)38)28-15-2-4-16(5-3-15)37(39)40/h1-8,13H,9-12H2,(H3,26,33,38)(H,27,29,41)(H2,28,30,31,32,34)
  • InChiKey: LWCWGJNXYXUOIJ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0035 0.0503 0.0483
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0825 0.0806
Echinococcus multilocularis snurportin 1 0.032 0.7058 0.7058
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0388 0.0388
Onchocerca volvulus 0.0028 0.0336 0.0315
Echinococcus granulosus expressed conserved protein 0.0096 0.1902 0.1902
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0699 0.0699
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0825 0.1949
Leishmania major importin beta-1 subunit, putative 0.0024 0.0247 0.2807
Brugia malayi Calcitonin receptor-like protein seb-1 0.0052 0.0881 0.0861
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0537 0.1252
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0825 0.1949
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0021 0.0021
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.4671 0.4671
Echinococcus multilocularis peregrin 0.003 0.0388 0.0388
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0052 0.0881 0.0881
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0021 0.0021
Onchocerca volvulus 0.0031 0.0402 0.0381
Onchocerca volvulus 0.0049 0.0825 0.0806
Brugia malayi Pre-SET motif family protein 0.0216 0.4671 0.466
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0195 0.4884
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0065 0.0044
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0825 0.0806
Brugia malayi hypothetical protein 0.0247 0.5377 0.5367
Plasmodium falciparum importin beta, putative 0.003 0.0377 0.6902
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0375 0.0375
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0195 0.0195
Onchocerca volvulus 0.0028 0.0336 0.0315
Loa Loa (eye worm) hypothetical protein 0.0037 0.0537 0.0537
Schistosoma mansoni hypothetical protein 0.032 0.7058 0.7052
Loa Loa (eye worm) hypothetical protein 0.0049 0.0825 0.0825
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0065 0.0065
Entamoeba histolytica glycogen phosphorylase, putative 0.0194 0.4146 0.4134
Loa Loa (eye worm) hypothetical protein 0.0102 0.2045 0.2045
Brugia malayi CHE-14 protein 0.0044 0.0699 0.0679
Trichomonas vaginalis glycogen phosphorylase, putative 0.0448 1 1
Mycobacterium ulcerans hypothetical protein 0.0049 0.0825 0.1949
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0491 0.1139
Entamoeba histolytica glycogen phosphorylase, putative 0.0448 1 1
Echinococcus granulosus glycogen phosphorylase 0.0448 1 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0195 0.0195
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0402 0.0402
Loa Loa (eye worm) oxidoreductase 0.0015 0.0021 0.0021
Echinococcus granulosus tumor protein p63 0.0353 0.7817 0.7817
Echinococcus multilocularis glycogen phosphorylase 0.0448 1 1
Plasmodium vivax hypothetical protein, conserved 0.003 0.0388 0.7114
Echinococcus granulosus glycogen phosphorylase 0.0448 1 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0537 0.0537
Echinococcus granulosus GPCR family 2 0.0016 0.0065 0.0065
Echinococcus granulosus survival motor neuron protein 1 0.0247 0.5377 0.5377
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0825 0.1949
Onchocerca volvulus 0.0019 0.0114 0.0093
Echinococcus granulosus Niemann Pick C1 protein 0.0146 0.3056 0.3056
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0553 0.0533
Plasmodium vivax importin-beta 2, putative 0.003 0.0377 0.6902
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0491 0.1139
Schistosoma mansoni hypothetical protein 0.0016 0.0065 0.0044
Echinococcus multilocularis glycogen phosphorylase 0.0448 1 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0195 0.3371
Brugia malayi Pre-SET motif family protein 0.0031 0.0402 0.0381
Echinococcus multilocularis lamin 0.0028 0.0336 0.0336
Echinococcus multilocularis tumor protein p63 0.0353 0.7817 0.7817
Echinococcus multilocularis lamin dm0 0.0028 0.0336 0.0336
Brugia malayi MH2 domain containing protein 0.0125 0.2559 0.2544
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0388 0.0388
Entamoeba histolytica hypothetical protein 0.0038 0.0553 0.0533
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0065 0.0065
Brugia malayi jmjC domain containing protein 0.0037 0.0536 0.0516
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0825 0.0806
Loa Loa (eye worm) hypothetical protein 0.0035 0.0503 0.0503
Schistosoma mansoni ran 0.0022 0.0195 0.0174
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0825 0.1949
Loa Loa (eye worm) hypothetical protein 0.0052 0.089 0.089
Entamoeba histolytica glycogen phosphorylase, putative 0.0194 0.4146 0.4134
Entamoeba histolytica Ran family GTPase 0.0022 0.0195 0.0174
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0104 0.2081 0.2064
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0065 0.0044
Loa Loa (eye worm) hypothetical protein 0.0028 0.0336 0.0336
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0247 0.0226
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0825 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0537 0.0537
Echinococcus granulosus Glycosyl transferase family 35 0.0448 1 1
Giardia lamblia PHD finger protein 15 0.003 0.0388 0.0197
Onchocerca volvulus 0.0246 0.5359 0.535
Entamoeba histolytica glycogen phosphorylase, putative 0.0448 1 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0402 0.0381
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0402 0.0381
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0699 0.0699
Echinococcus multilocularis musashi 0.0028 0.0336 0.0336
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0034 0.0034
Echinococcus multilocularis expressed conserved protein 0.0096 0.1902 0.1902
Brugia malayi Bromodomain containing protein 0.003 0.0388 0.0368
Loa Loa (eye worm) hypothetical protein 0.003 0.0388 0.0388
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0402 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0065 0.0065
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0052 0.0881 0.0861
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0663 0.0663
Brugia malayi RNA, U transporter 1 0.0085 0.165 0.1633
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0536 0.0516
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0194 0.4146 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0881 0.0881
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0195 0.0174
Chlamydia trachomatis glycogen phosphorylase 0.0448 1 1
Loa Loa (eye worm) hypothetical protein 0.0052 0.0877 0.0877
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0195 0.7709
Entamoeba histolytica hypothetical protein 0.0038 0.0553 0.0533
Onchocerca volvulus Glycogen phosphorylase homolog 0.0448 1 1
Schistosoma mansoni hypothetical protein 0.0042 0.0662 0.0642
Loa Loa (eye worm) transcription factor SMAD2 0.0125 0.2559 0.2559
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0537 0.1252
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0825 1
Brugia malayi jmjC domain containing protein 0.01 0.1984 0.1967
Schistosoma mansoni glycogen phosphorylase 0.0194 0.4146 0.4134
Schistosoma mansoni lamin 0.0028 0.0336 0.0315
Brugia malayi hypothetical protein 0.0038 0.0553 0.0533
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0377 1
Entamoeba histolytica glycogenphosphorylase, putative 0.0194 0.4146 0.4134
Echinococcus multilocularis Niemann Pick C1 protein 0.0146 0.3056 0.3056
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0553 0.0553
Schistosoma mansoni hypothetical protein 0.005 0.0847 0.0828
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0663 0.0663
Loa Loa (eye worm) hypothetical protein 0.0031 0.0402 0.0402
Plasmodium falciparum phd finger protein, putative 0.003 0.0388 0.7114
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.01 0.1984 0.1984
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0247 1
Echinococcus granulosus snurportin 1 0.032 0.7058 0.7058
Echinococcus granulosus lamin dm0 0.0028 0.0336 0.0336
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0388 0.9649
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0195 0.7709
Echinococcus multilocularis protein dispatched 1 0.005 0.0842 0.0842
Loa Loa (eye worm) hypothetical protein 0.0044 0.0699 0.0699
Schistosoma mansoni hypothetical protein 0.0177 0.3764 0.3751
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0388 0.0368
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0247 0.0226
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0536 0.0536
Schistosoma mansoni hypothetical protein 0.0016 0.0065 0.0044
Brugia malayi Niemann-Pick C1 protein precursor 0.0102 0.2045 0.2028
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0536 0.0516
Loa Loa (eye worm) hypothetical protein 0.0049 0.0825 0.0825
Schistosoma mansoni glycogen phosphorylase 0.0448 1 1
Brugia malayi Intermediate filament tail domain containing protein 0.0028 0.0336 0.0315
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0388 0.0388
Schistosoma mansoni hypothetical protein 0.003 0.0388 0.0368
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0102 0.2045 0.2028
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0537 1
Brugia malayi PHD-finger family protein 0.003 0.0388 0.0368
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0825 0.0806
Loa Loa (eye worm) MH2 domain-containing protein 0.0125 0.2559 0.2559
Echinococcus multilocularis Glycosyl transferase, family 35 0.0448 1 1
Trypanosoma brucei importin beta-1 subunit, putative 0.003 0.0377 1
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0536 0.0536
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0065 0.0065
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0028 0.0336 0.0336
Schistosoma mansoni patched 1 0.0044 0.0699 0.0679
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0699 0.0699
Brugia malayi Importin beta-1 subunit 0.003 0.0377 0.0357
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0699 0.0699
Schistosoma mansoni lamin 0.0028 0.0336 0.0315
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0194 0.4146 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Onchocerca volvulus Alhambra homolog 0.003 0.0388 0.0368
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0503 0.0483
Schistosoma mansoni cellular tumor antigen P53 0.0052 0.0877 0.0858
Schistosoma mansoni intermediate filament proteins 0.0028 0.0336 0.0315
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0825 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0324 0.0324
Onchocerca volvulus 0.005 0.0847 0.0828
Schistosoma mansoni jumonji domain containing protein 0.0079 0.1512 0.1494
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0402 0.0381
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0825 0.1949
Toxoplasma gondii HEAT repeat-containing protein 0.003 0.0377 0.936
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0402 0.0402
Entamoeba histolytica hypothetical protein 0.0038 0.0553 0.0533
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0825 0.1949
Loa Loa (eye worm) hypothetical protein 0.0037 0.0537 0.0537
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0065 0.0065
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.01 0.1984 0.1984
Schistosoma mansoni hypothetical protein 0.0042 0.0662 0.0642
Loa Loa (eye worm) hypothetical protein 0.0049 0.0825 0.0825
Schistosoma mansoni glycogen phosphorylase 0.0448 1 1
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.005 0.0847 0.0828
Loa Loa (eye worm) intermediate filament protein 0.0028 0.0336 0.0336
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0247 0.0226
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0825 0.1949
Entamoeba histolytica hypothetical protein 0.0024 0.0247 0.0226
Plasmodium vivax SET domain protein, putative 0.0031 0.0402 0.7373
Brugia malayi intermediate filament protein 0.0028 0.0336 0.0315
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0825 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0065 0.0065
Schistosoma mansoni hypothetical protein 0.0038 0.0553 0.0533
Echinococcus multilocularis Niemann Pick C1 protein 0.0102 0.2045 0.2045
Echinococcus granulosus Niemann Pick C1 protein 0.0102 0.2045 0.2045
Schistosoma mansoni hypothetical protein 0.0016 0.0065 0.0044
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0195 0.4571
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0388 0.9649
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0195 0.3371
Trichomonas vaginalis glycogen phosphorylase, putative 0.0448 1 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0021 0.0021
Echinococcus multilocularis protein patched 0.0044 0.0699 0.0699
Loa Loa (eye worm) hypothetical protein 0.0015 0.0021 0.0021
Echinococcus granulosus intermediate filament protein 0.0028 0.0336 0.0336
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0825 0.0806
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0825 0.1949
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0825 0.1949
Loa Loa (eye worm) glycogen phosphorylase 0.0448 1 1
Schistosoma mansoni hypothetical protein 0.0042 0.0662 0.0642
Echinococcus multilocularis GPCR, family 2 0.0016 0.0065 0.0065
Schistosoma mansoni importin beta-1 0.003 0.0377 0.0357
Echinococcus granulosus importin subunit beta 1 0.003 0.0377 0.0377
Schistosoma mansoni survival motor neuron protein 0.005 0.0847 0.0828
Echinococcus granulosus geminin 0.0177 0.3764 0.3764
Echinococcus granulosus peregrin 0.003 0.0388 0.0388
Loa Loa (eye worm) hypothetical protein 0.0037 0.0537 0.0537
Trichomonas vaginalis set domain proteins, putative 0.0246 0.5359 0.535
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0491 0.1139
Schistosoma mansoni hypothetical protein 0.0177 0.3764 0.3751
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0402 0.0402
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0825 0.0806
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0491 0.1139
Schistosoma mansoni ran 0.0022 0.0195 0.0174
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0825 1
Leishmania major GTP-binding protein, putative 0.0022 0.0195 0.2164
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.1135 0.1135
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0402 0.0381
Trichomonas vaginalis ran, putative 0.0022 0.0195 0.0174
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0699 0.0679
Echinococcus multilocularis importin subunit beta 1 0.003 0.0377 0.0377
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0536 0.0536
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0034 0.0013
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0021 0.0021
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0553 0.0553
Onchocerca volvulus 0.0052 0.0877 0.0858
Loa Loa (eye worm) hypothetical protein 0.003 0.0377 0.0377
Schistosoma mansoni hypothetical protein 0.0016 0.0065 0.0044
Echinococcus multilocularis survival motor neuron protein 1 0.0247 0.5377 0.5377
Entamoeba histolytica hypothetical protein 0.0038 0.0553 0.0533
Echinococcus granulosus lamin 0.0028 0.0336 0.0336
Loa Loa (eye worm) hypothetical protein 0.0054 0.0926 0.0926
Echinococcus multilocularis geminin 0.0177 0.3764 0.3764
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0537 1
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0195 0.0195
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.032 0.7058 0.7058
Giardia lamblia Glycogen phosphorylase 0.0448 1 1
Loa Loa (eye worm) hypothetical protein 0.0247 0.5377 0.5377
Schistosoma mansoni hypothetical protein 0.0042 0.0662 0.0642

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 12.5 ug ml-1 Antibacterial activity against Escherichia coli NCIM 2065 assessed as growth inhibition after 24 hr by NCCLS broth dilution method ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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