Detailed information for compound 1798387

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 377.436 | Formula: C22H23N3O3
  • H donors: 0 H acceptors: 3 LogP: 3.66 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCc1cc(n(n1)C)C(=O)N(C(=O)C)Cc1ccc(cc1)Oc1ccccc1
  • InChi: 1S/C22H23N3O3/c1-4-18-14-21(24(3)23-18)22(27)25(16(2)26)15-17-10-12-20(13-11-17)28-19-8-6-5-7-9-19/h5-14H,4,15H2,1-3H3
  • InChiKey: IJTQMLSVANKCSF-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis cysteine protease 0.033 0.5158 0.5322
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0936 0.1798
Echinococcus granulosus tar DNA binding protein 0.0127 0.1801 0.1852
Brugia malayi chromobox protein homolog 3 0.0038 0.0332 0.0333
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.033 0.5158 1
Echinococcus multilocularis cathepsin L cysteine protease 0.033 0.5158 0.5322
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0226 0.3446 0.3553
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0936 0.1798
Schistosoma mansoni cathepsin F (C01 family) 0.033 0.5158 0.5322
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0402 0.0405
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0074 0.0936 0.1798
Brugia malayi Papain family cysteine protease containing protein 0.0074 0.0936 0.0957
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0667 0.1276
Plasmodium falciparum cysteine proteinase falcipain 2a 0.033 0.5158 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0605 0.9683 1
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0074 0.0936 0.1798
Echinococcus multilocularis expressed conserved protein 0.0092 0.1225 0.1256
Giardia lamblia Cathepsin B precursor 0.0074 0.0936 0.2334
Plasmodium falciparum cysteine proteinase falcipain 3 0.033 0.5158 1
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0667 0.1276
Entamoeba histolytica cysteine protease, putative 0.033 0.5158 1
Schistosoma mansoni amine oxidase 0.007 0.0863 0.0882
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0074 0.0936 0.0957
Giardia lamblia Cathepsin L-like protease 0.0074 0.0936 0.2334
Giardia lamblia Cathepsin L precursor 0.0074 0.0936 0.2334
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0074 0.0936 0.0966
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Toxoplasma gondii cathepsin CPC1 0.0074 0.0936 0.1798
Echinococcus multilocularis tar DNA binding protein 0.0127 0.1801 0.1852
Brugia malayi Cathepsin L-like precursor 0.033 0.5158 0.5322
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.2016 0.2073
Plasmodium falciparum serine repeat antigen 2 0.0074 0.0936 0.1814
Schistosoma mansoni cathepsin s 0.0104 0.1421 0.1459
Trypanosoma cruzi metacaspase, putative 0.0058 0.0667 0.0679
Onchocerca volvulus 0.003 0.0198 0.0197
Plasmodium falciparum cysteine proteinase falcipain 1 0.0178 0.2648 0.5133
Toxoplasma gondii histone lysine-specific demethylase 0.007 0.0863 0.1657
Echinococcus granulosus GPCR family 2 0.0062 0.0737 0.0751
Brugia malayi cathepsin F-like cysteine proteinase 0.0104 0.1421 0.1459
Giardia lamblia Cathepsin B precursor 0.0074 0.0936 0.2334
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0098
Echinococcus multilocularis chromobox protein 1 0.0067 0.082 0.0838
Schistosoma mansoni cathepsin B (C01 family) 0.0074 0.0936 0.0957
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.1323 0.2551
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.1348 0.1383
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0178 0.2648 0.2727
Onchocerca volvulus 0.033 0.5158 1
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0178 0.2648 0.2727
Echinococcus multilocularis protein kinase shaggy 0.0259 0.3976 0.4101
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.001 0.001
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0098 0.0171
Schistosoma mansoni cathepsin C 0.0074 0.0936 0.0957
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0259 0.3976 0.4101
Brugia malayi Cathepsin L-like precursor 0.0226 0.3446 0.3553
Onchocerca volvulus Cathepsin L homolog 0.0074 0.0936 0.1655
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0098
Brugia malayi Cathepsin L-like precursor 0.033 0.5158 0.5322
Brugia malayi Heterochromatin protein 1 0.0067 0.082 0.0838
Toxoplasma gondii preprocathepsin c precursor, putative 0.0074 0.0936 0.1798
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.5158 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0098 0.0098
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0135 0.1931 0.1994
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.001 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Plasmodium falciparum serine repeat antigen 4 0.0074 0.0936 0.1814
Echinococcus multilocularis caspase 3 0.0159 0.2333 0.2402
Echinococcus granulosus caspase 3 0.0159 0.2333 0.2402
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0058 0.0667 0.0679
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0101
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0178 0.2648 0.2727
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0259 0.3976 0.7705
Loa Loa (eye worm) hypothetical protein 0.0134 0.1928 0.1991
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0667 0.1276
Brugia malayi intracellular kinase 0.0259 0.3976 0.4101
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0074 0.0936 0.1814
Loa Loa (eye worm) hypothetical protein 0.0074 0.0936 0.0966
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0197 0.2955 0.3045
Trypanosoma brucei cysteine peptidase C (CPC) 0.0238 0.3641 0.7053
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0098 0.0111
Trypanosoma cruzi cruzipain precursor, putative 0.0104 0.1421 0.1459
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0332 0.0626
Trypanosoma cruzi metacaspase 5, putative 0.0058 0.0667 0.0679
Schistosoma mansoni tar DNA-binding protein 0.0127 0.1801 0.1852
Plasmodium vivax glycogen synthase kinase 3, putative 0.0259 0.3976 0.7709
Echinococcus multilocularis 0.007 0.0863 0.0882
Leishmania major UDP-galactopyranose mutase 0.007 0.0863 0.1657
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0667 0.1276
Echinococcus multilocularis chromobox protein 1 0.0067 0.082 0.0838
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.0091
Plasmodium falciparum serine repeat antigen 6 0.0074 0.0936 0.1814
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0667 0.1276
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0098 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0936 0.1798
Loa Loa (eye worm) hypothetical protein 0.0226 0.3446 0.3559
Mycobacterium ulcerans oxidoreductase 0.007 0.0863 0.0863
Schistosoma mansoni chromobox protein 0.0067 0.082 0.0838
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.007 0.0863 0.1674
Schistosoma mansoni tar DNA-binding protein 0.0127 0.1801 0.1852
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0115 0.1612 0.1665
Leishmania major metacaspase, putative 0.0058 0.0667 0.1276
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0178 0.2648 0.5123
Echinococcus multilocularis protoporphyrinogen oxidase 0.007 0.0863 0.0882
Giardia lamblia Cathepsin B precursor 0.0074 0.0936 0.2334
Brugia malayi fibroinase precursor 0.0074 0.0936 0.0957
Plasmodium vivax serine-repeat antigen (SERA) 0.0074 0.0936 0.1814
Entamoeba histolytica cysteine proteinase 2 0.0178 0.2648 0.5123
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0104 0.1421 0.1468
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Onchocerca volvulus 0.0226 0.3446 0.6617
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0936 0.1798
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0074 0.0936 0.2334
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0074 0.0936 0.0957
Entamoeba histolytica cysteine proteinase, putative 0.0226 0.3446 0.6675
Brugia malayi cathepsin L-like precursor 0.0226 0.3446 0.3553
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Schistosoma mansoni patched 1 0.0042 0.0402 0.0405
Plasmodium falciparum cysteine proteinase falcipain 2b 0.033 0.5158 1
Entamoeba histolytica cysteine proteinase, putative 0.0178 0.2648 0.5123
Brugia malayi Cathepsin L-like precursor 0.033 0.5158 0.5322
Giardia lamblia Cathepsin L precursor 0.0074 0.0936 0.2334
Giardia lamblia Cathepsin L precursor 0.0074 0.0936 0.2334
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0379 0.0718
Leishmania major cathepsin L-like protease 0.033 0.5158 1
Entamoeba histolytica protein kinase domain containing protein 0.0259 0.3976 0.7705
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0074 0.0936 0.0957
Brugia malayi Calcitonin receptor-like protein seb-1 0.0197 0.2955 0.3045
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0098 0.0098
Leishmania major cathepsin L-like protease 0.033 0.5158 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.5158 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.5158 1
Trypanosoma cruzi metacaspase, putative 0.0058 0.0667 0.0679
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0667 0.1276
Giardia lamblia Cysteine protease 0.0074 0.0936 0.2334
Trypanosoma brucei Metacaspase-4 0.0058 0.0667 0.1276
Loa Loa (eye worm) TAR-binding protein 0.0127 0.1801 0.186
Loa Loa (eye worm) cysteine protease 0.033 0.5158 0.5327
Plasmodium falciparum protoporphyrinogen oxidase 0.007 0.0863 0.1674
Echinococcus granulosus cathepsin b 0.0605 0.9683 1
Schistosoma mansoni hypothetical protein 0.0062 0.0737 0.0751
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0074 0.0936 0.1814
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.2016 0.2073
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0074 0.0936 0.1814
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0171
Entamoeba histolytica protein kinase domain containing protein 0.0259 0.3976 0.7705
Loa Loa (eye worm) hypothetical protein 0.033 0.5158 0.5327
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0171
Loa Loa (eye worm) hypothetical protein 0.0082 0.1055 0.109
Plasmodium falciparum metacaspase 1 0.0058 0.0667 0.1293
Echinococcus granulosus chromobox protein 1 0.0067 0.082 0.0838
Loa Loa (eye worm) hypothetical protein 0.007 0.0863 0.0892
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0074 0.0936 0.1814
Echinococcus granulosus cathepsin L cysteine protease 0.0178 0.2648 0.2727
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.1931 0.1986
Trichomonas vaginalis conserved hypothetical protein 0.0074 0.0936 0.1798
Echinococcus granulosus cathepsin l cysteine peptidase 0.033 0.5158 0.5322
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.001 0.5
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0062 0.0737 0.0751
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0074 0.0936 0.2334
Echinococcus granulosus cathepsin l1 0.0226 0.3446 0.3553
Echinococcus granulosus cathepsin L cysteine proteinase 0.033 0.5158 0.5322
Brugia malayi Papain family cysteine protease containing protein 0.0178 0.2648 0.2727
Schistosoma mansoni caspase-3 (C14 family) 0.0217 0.3291 0.3392
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0074 0.0936 0.0966
Trichomonas vaginalis chromobox protein, putative 0.0067 0.082 0.1574
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0217 0.3291 0.3392
Giardia lamblia Cathepsin B precursor 0.0238 0.3641 0.9155
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0238 0.3641 0.3754
Loa Loa (eye worm) hypothetical protein 0.0058 0.0667 0.0689
Schistosoma mansoni amine oxidase 0.007 0.0863 0.0882
Brugia malayi Cathepsin L-like precursor 0.033 0.5158 0.5322
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0259 0.3976 0.4107
Plasmodium vivax vivapain-1 0.0178 0.2648 0.5133
Loa Loa (eye worm) hypothetical protein 0.0058 0.0667 0.0689
Brugia malayi Cell death protein 3 precursor 0.0058 0.0667 0.0679
Entamoeba histolytica cysteine protease, putative 0.0074 0.0936 0.1798
Echinococcus multilocularis caspase 0.0217 0.3291 0.3392
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0074 0.0936 0.2334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0074 0.0936 0.0957
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0667 0.1293
Echinococcus multilocularis cysteine protease 0.033 0.5158 0.5322
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0402 0.0405
Echinococcus multilocularis cathepsin L 0.0074 0.0936 0.0957
Entamoeba histolytica protein kinase, putative 0.0259 0.3976 0.7705
Plasmodium falciparum serine repeat antigen 7 0.0074 0.0936 0.1814
Entamoeba histolytica hypothetical protein 0.0074 0.0936 0.1798
Plasmodium vivax hypothetical protein, conserved 0.007 0.0863 0.1674
Schistosoma mansoni hypothetical protein 0.004 0.0377 0.038
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0135 0.1931 0.1986
Schistosoma mansoni Protoporphyrinogen oxidase chloroplast/mitochondrial precursor 0.007 0.0863 0.0882
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0074 0.0936 0.1798
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Plasmodium vivax protoporphyrinogen oxidase, putative 0.007 0.0863 0.1674
Brugia malayi Papain family cysteine protease containing protein 0.0178 0.2648 0.2727
Plasmodium falciparum metacaspase-like protein 0.0058 0.0667 0.1293
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0402 0.0415
Toxoplasma gondii cathepsin CPC2 0.0074 0.0936 0.1798
Loa Loa (eye worm) hypothetical protein 0.0605 0.9683 1
Onchocerca volvulus 0.0191 0.2865 0.5468
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0074 0.0936 0.0966
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0074 0.0936 0.1814
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0936 0.1798
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.033 0.5158 1
Leishmania major cathepsin L-like protease 0.033 0.5158 1
Entamoeba histolytica cysteine proteinase, putative 0.033 0.5158 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0074 0.0936 0.1814
Entamoeba histolytica cysteine proteinase, putative 0.0178 0.2648 0.5123
Plasmodium falciparum serine repeat antigen 3 0.0074 0.0936 0.1814
Schistosoma mansoni hypothetical protein 0.004 0.0377 0.038
Entamoeba histolytica cysteine proteinase, putative 0.0178 0.2648 0.5123
Loa Loa (eye worm) cathepsin B 0.0238 0.3641 0.376
Plasmodium vivax vivapain-3 0.0178 0.2648 0.5133
Brugia malayi Cathepsin L-like precursor 0.033 0.5158 0.5322
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Brugia malayi cathepsin L precursor 0.0074 0.0936 0.0957
Loa Loa (eye worm) fibroinase 0.033 0.5158 0.5327
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0098 0.0171
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0098 0.0111
Loa Loa (eye worm) hypothetical protein 0.0051 0.0558 0.0576
Giardia lamblia Cathepsin B precursor 0.0238 0.3641 0.9155
Onchocerca volvulus Cell death protein 3 homolog 0.0058 0.0667 0.1124
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0074 0.0936 0.1798
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0127 0.1801 0.186
Loa Loa (eye worm) hypothetical protein 0.0191 0.2865 0.2959
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Trypanosoma cruzi cysteine peptidase, putative 0.0178 0.2648 0.2727
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Trypanosoma brucei metacaspase MCA2 0.0058 0.0667 0.1276
Leishmania major cysteine peptidase A (CPA) 0.033 0.5158 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0667 0.1276
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Schistosoma mansoni cathepsin F (C01 family) 0.0226 0.3446 0.3553
Trypanosoma cruzi major cysteine proteinase, putative 0.0074 0.0936 0.0957
Trypanosoma brucei protein kinase, putative 0.0259 0.3976 0.7705
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0074 0.0936 0.1814
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0197 0.2955 0.3052
Entamoeba histolytica cysteine protease, putative 0.0074 0.0936 0.1798
Giardia lamblia Cathepsin L precursor 0.0074 0.0936 0.2334
Brugia malayi RNA binding protein 0.0127 0.1801 0.1852
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0667 0.1276
Mycobacterium tuberculosis Possible oxidoreductase 0.007 0.0863 0.0976
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.5158 1
Onchocerca volvulus 0.0074 0.0936 0.1655
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0074 0.0936 0.1798
Loa Loa (eye worm) RNA binding protein 0.0127 0.1801 0.186
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0936 0.1798
Schistosoma mansoni hypothetical protein 0.0134 0.1928 0.1983
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0074 0.0936 0.1798
Giardia lamblia Cathepsin L-like protease 0.0074 0.0936 0.2334
Loa Loa (eye worm) hypothetical protein 0.0074 0.0936 0.0966
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0074 0.0936 0.0957
Brugia malayi Cathepsin L-like precursor 0.0226 0.3446 0.3553
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.5158 1
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.015 0.0273
Loa Loa (eye worm) papain family cysteine protease containing protein 0.033 0.5158 0.5327
Brugia malayi Cathepsin L-like precursor 0.033 0.5158 0.5322
Entamoeba histolytica cysteine protease, putative 0.0074 0.0936 0.1798
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.5158 1
Entamoeba histolytica cysteine proteinase, putative 0.0178 0.2648 0.5123
Schistosoma mansoni hypothetical protein 0.0062 0.0737 0.0751
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0605 0.9683 1
Echinococcus granulosus chromobox protein 1 0.0067 0.082 0.0838
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0936 0.1798
Loa Loa (eye worm) hypothetical protein 0.0104 0.1421 0.1468
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.1931 0.1986
Trypanosoma cruzi major cysteine proteinase, putative 0.0074 0.0936 0.0957
Echinococcus granulosus cathepsin l1 0.033 0.5158 0.5322
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.1931 0.1986
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0058 0.0667 0.0679
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Giardia lamblia Cysteine protease 0.0074 0.0936 0.2334
Echinococcus multilocularis protein dispatched 1 0.0048 0.05 0.0506
Schistosoma mansoni tar DNA-binding protein 0.0127 0.1801 0.1852
Brugia malayi Latrophilin receptor protein 2 0.0062 0.0737 0.0751
Brugia malayi cathepsin L-like cysteine proteinase 0.0074 0.0936 0.0957
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.015 0.0273
Loa Loa (eye worm) hypothetical protein 0.0197 0.2955 0.3052
Trypanosoma cruzi UDP-galactopyranose mutase 0.007 0.0863 0.0882
Brugia malayi hypothetical protein 0.007 0.0863 0.0882
Echinococcus multilocularis cathepsin l cysteine peptidase 0.033 0.5158 0.5322
Loa Loa (eye worm) hypothetical protein 0.0074 0.0936 0.0966
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0605 0.9683 1
Schistosoma mansoni hypothetical protein 0.004 0.0377 0.038
Loa Loa (eye worm) hypothetical protein 0.0074 0.0936 0.0966
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0074 0.0936 0.0957
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0098 0.0098
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0605 0.9683 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0402 0.0762
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.001 0.0019
Brugia malayi cathepsin Z-like cysteine proteinase 0.0074 0.0936 0.0957
Loa Loa (eye worm) hypothetical protein 0.0098 0.1323 0.1366
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0074 0.0936 0.0957
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0074 0.0936 0.1814
Trypanosoma cruzi cruzipain precursor, putative 0.033 0.5158 0.5322
Trypanosoma cruzi cysteine proteinase, putative 0.0178 0.2648 0.2727
Echinococcus multilocularis cathepsin b 0.0605 0.9683 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0058 0.0667 0.1276
Plasmodium vivax hypothetical protein, conserved 0.007 0.0863 0.1674
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.001 0.0019
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0936 0.1798
Giardia lamblia Hypothetical protein 0.0074 0.0936 0.2334
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.1323 0.1358
Schistosoma mansoni hypothetical protein 0.0164 0.241 0.2482
Echinococcus granulosus cysteine protease 0.0178 0.2648 0.2727
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.1931 0.1986
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0259 0.3976 0.4101
Plasmodium falciparum serine repeat antigen 9 0.0074 0.0936 0.1814
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0074 0.0936 0.1814
Trypanosoma cruzi UDP-galactopyranose mutase 0.007 0.0863 0.0882
Trypanosoma brucei metacaspase MCA3 0.0058 0.0667 0.1276
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0098 0.0171
Schistosoma mansoni tar DNA-binding protein 0.0127 0.1801 0.1852
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0062 0.0737 0.0751
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.1323 0.1358
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0624 1 1
Onchocerca volvulus 0.033 0.5158 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.0091
Echinococcus granulosus cathepsin L 0.0178 0.2648 0.2727
Loa Loa (eye worm) hypothetical protein 0.0226 0.3446 0.3559
Giardia lamblia Encystation-specific protease 0.0074 0.0936 0.2334
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0178 0.2648 0.5123
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Entamoeba histolytica cysteine proteinase 1, putative 0.0178 0.2648 0.5123
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.1323 0.1358
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Giardia lamblia Hypothetical protein 0.0074 0.0936 0.2334
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0074 0.0936 0.2334
Echinococcus granulosus cathepsin L 0.0074 0.0936 0.0957
Brugia malayi TAR-binding protein 0.0127 0.1801 0.1852
Echinococcus multilocularis cathepsin L 0.0178 0.2648 0.2727
Schistosoma mansoni hypothetical protein 0.0062 0.0737 0.0751
Brugia malayi Cathepsin L-like cysteine proteinase 0.0226 0.3446 0.3553
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0178 0.2648 0.5123
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.007 0.0863 0.1674
Onchocerca volvulus 0.033 0.5158 1
Echinococcus multilocularis GPCR, family 2 0.0062 0.0737 0.0751
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0074 0.0936 0.1814
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0259 0.3976 0.4101
Brugia malayi Papain family cysteine protease containing protein 0.0074 0.0936 0.0957
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0074 0.0936 0.1798
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.001 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0074 0.0936 0.1798
Mycobacterium ulcerans dehydrogenase 0.007 0.0863 0.0863
Leishmania major cathepsin L-like protease 0.033 0.5158 1
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0667 0.1276
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0074 0.0936 0.1798
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0259 0.3976 0.4107
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0062 0.0737 0.0751
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.5158 1
Loa Loa (eye worm) hypothetical protein 0.0074 0.0936 0.0966
Plasmodium vivax metacaspase 1, putative 0.0058 0.0667 0.1293
Schistosoma mansoni caspase-7 (C14 family) 0.0058 0.0667 0.0679
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.007 0.0863 0.1657
Onchocerca volvulus Cathepsin L homolog 0.033 0.5158 1
Brugia malayi Papain family cysteine protease containing protein 0.033 0.5158 0.5322
Schistosoma mansoni hypothetical protein 0.004 0.0377 0.038
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0058 0.0667 0.1276
Trypanosoma cruzi cysteine peptidase, putative 0.033 0.5158 0.5322
Schistosoma mansoni hypothetical protein 0.0164 0.241 0.2482
Schistosoma mansoni hypothetical protein 0.0062 0.0737 0.0751
Brugia malayi cathepsin B-like cysteine proteinase 0.0605 0.9683 1
Giardia lamblia Cathepsin L precursor 0.0074 0.0936 0.2334
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0667 0.1276
Schistosoma mansoni caspase-7 (C14 family) 0.0217 0.3291 0.3392
Plasmodium falciparum glycogen synthase kinase 3 0.0259 0.3976 0.7709
Loa Loa (eye worm) hypothetical protein 0.003 0.0198 0.0204
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.1931 0.1986
Onchocerca volvulus Cathepsin F homolog 0.033 0.5158 1
Brugia malayi amine oxidase, flavin-containing family protein 0.0082 0.1055 0.1081
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0178 0.2648 0.2727
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.3446 0.6675
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0605 0.9683 1
Trichomonas vaginalis chromobox protein, putative 0.0067 0.082 0.1574
Brugia malayi MH2 domain containing protein 0.0115 0.1612 0.1657
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0104 0.1421 0.1459
Trypanosoma cruzi cysteine peptidase, putative 0.033 0.5158 0.5322
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.1931 0.1986
Loa Loa (eye worm) hypothetical protein 0.0226 0.3446 0.3559
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0332 0.0462
Echinococcus multilocularis cathepsin L cysteine protease 0.033 0.5158 0.5322
Brugia malayi SWIRM domain containing protein 0.0191 0.2865 0.2951
Entamoeba histolytica cysteine protease, putative 0.0074 0.0936 0.1798
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0238 0.3641 0.7053
Loa Loa (eye worm) hypothetical protein 0.018 0.2673 0.276
Onchocerca volvulus 0.033 0.5158 1
Echinococcus granulosus lysine specific histone demethylase 1A 0.007 0.0863 0.0882
Loa Loa (eye worm) hypothetical protein 0.0062 0.0737 0.0761
Trypanosoma cruzi metacaspase, putative 0.0058 0.0667 0.0679
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0101
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.5158 1
Brugia malayi CHE-14 protein 0.0042 0.0402 0.0405
Echinococcus granulosus cathepsin b 0.0605 0.9683 1
Echinococcus granulosus geminin 0.0164 0.241 0.2482
Giardia lamblia Cathepsin B precursor 0.0074 0.0936 0.2334
Entamoeba histolytica cysteine protease, putative 0.0074 0.0936 0.1798
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.033 0.5158 1
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0667 0.1276
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0238 0.3641 0.3754
Leishmania major cathepsin L-like protease 0.033 0.5158 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0178 0.2648 0.5123
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Brugia malayi Cathepsin L-like precursor 0.0104 0.1421 0.1459
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0667 0.1276
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0226 0.3446 0.6675
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0074 0.0936 0.0957
Schistosoma mansoni cathepsin S (C01 family) 0.0074 0.0936 0.0957
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0332 0.0626
Toxoplasma gondii cathepsin CPL 0.033 0.5158 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0074 0.0936 0.1798
Schistosoma mansoni Lysine-specific histone demethylase 1 0.018 0.2673 0.2753
Plasmodium vivax vivapain-2 0.033 0.5158 1
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Trypanosoma brucei metacaspase 0.0058 0.0667 0.1276
Echinococcus granulosus caspase 2 0.0058 0.0667 0.0679
Onchocerca volvulus Cathepsin L homolog 0.033 0.5158 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0074 0.0936 0.0957
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Echinococcus granulosus expressed conserved protein 0.0092 0.1225 0.1256
Loa Loa (eye worm) ctsf protein 0.033 0.5158 0.5327
Brugia malayi Papain family cysteine protease containing protein 0.0074 0.0936 0.0957
Mycobacterium ulcerans hypothetical protein 0.0024 0.0098 0.0098
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0074 0.0936 0.1798
Mycobacterium tuberculosis Conserved hypothetical protein 0.007 0.0863 0.0976
Plasmodium falciparum serine repeat antigen 8 0.0074 0.0936 0.1814
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0379 0.0718
Mycobacterium ulcerans protoporphyrinogen oxidase 0.007 0.0863 0.0863
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0074 0.0936 0.1814
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0217 0.3291 0.3392
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0074 0.0936 0.0957
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0238 0.3641 0.7053
Plasmodium vivax vivapain-2 0.033 0.5158 1
Trypanosoma cruzi cysteine peptidase, putative 0.033 0.5158 0.5322
Trypanosoma cruzi metacaspase, putative 0.0058 0.0667 0.0679
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0098 0.0091
Echinococcus multilocularis cathepsin l cysteine peptidase 0.033 0.5158 0.5322
Loa Loa (eye worm) hypothetical protein 0.0104 0.1421 0.1468
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0554 0.8846 1
Mycobacterium ulcerans monoamine oxidase 0.007 0.0863 0.0863
Entamoeba histolytica cysteine proteinase, putative 0.033 0.5158 1
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0259 0.3976 0.4101
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0402 0.0405
Echinococcus multilocularis lysine specific histone demethylase 1A 0.018 0.2673 0.2753
Echinococcus granulosus caspase 8 0.0058 0.0667 0.0679
Loa Loa (eye worm) hypothetical protein 0.0042 0.0402 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.033 0.5158 1
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Chlamydia trachomatis protoporphyrinogen oxidase 0.007 0.0863 1
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0098 0.0098
Plasmodium vivax unspecified product 0.0178 0.2648 0.5133
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0667 0.1276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Giardia lamblia Cathepsin L precursor 0.0074 0.0936 0.2334
Trypanosoma cruzi cysteine proteinase, putative 0.0178 0.2648 0.2727
Trypanosoma cruzi metacaspase 5, putative 0.0058 0.0667 0.0679
Onchocerca volvulus 0.033 0.5158 1
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.3976 0.7705
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0062 0.0737 0.0751
Trypanosoma cruzi cysteine peptidase, putative 0.0104 0.1421 0.1459
Trichomonas vaginalis CMGC family protein kinase 0.0259 0.3976 0.7705
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0074 0.0936 0.1814
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.033 0.5158 0.5327
Schistosoma mansoni tar DNA-binding protein 0.0127 0.1801 0.1852
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0098 0.0171
Plasmodium falciparum serine repeat antigen 5 0.0074 0.0936 0.1814
Loa Loa (eye worm) latrophilin receptor protein 2 0.0062 0.0737 0.0761
Loa Loa (eye worm) hypothetical protein 0.0024 0.0098 0.0101
Giardia lamblia Cathepsin B precursor 0.0238 0.3641 0.9155
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0074 0.0936 0.0957
Plasmodium vivax serine-repeat antigen (SERA) 0.0074 0.0936 0.1814
Echinococcus multilocularis geminin 0.0164 0.241 0.2482
Onchocerca volvulus 0.033 0.5158 1
Echinococcus granulosus lysine specific histone demethylase 1A 0.018 0.2673 0.2753
Giardia lamblia Kinase, CMGC GSK 0.0259 0.3976 1
Plasmodium falciparum serine repeat antigen 1 0.0074 0.0936 0.1814
Leishmania major cathepsin L-like protease 0.033 0.5158 1
Giardia lamblia Kinase, CMGC GSK 0.0259 0.3976 1
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0379 0.0556
Plasmodium vivax unspecified product 0.0104 0.1421 0.2756
Schistosoma mansoni cathepsin F (C01 family) 0.033 0.5158 0.5322
Giardia lamblia Cysteine protease 0.0074 0.0936 0.2334
Onchocerca volvulus 0.033 0.5158 1
Giardia lamblia Cysteine protease 0.0074 0.0936 0.2334
Echinococcus granulosus protein kinase shaggy 0.0259 0.3976 0.4101
Loa Loa (eye worm) hypothetical protein 0.007 0.0863 0.0892
Echinococcus granulosus caspase 0.0217 0.3291 0.3392
Trypanosoma cruzi cysteine peptidase, putative 0.033 0.5158 0.5322
Leishmania major cathepsin L-like protease 0.033 0.5158 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0058 0.0667 0.1276
Loa Loa (eye worm) transcription factor SMAD2 0.0115 0.1612 0.1665
Brugia malayi RNA recognition motif domain containing protein 0.0127 0.1801 0.1852
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Echinococcus multilocularis cathepsin b 0.0605 0.9683 1
Echinococcus multilocularis caspase 8 0.0058 0.0667 0.0679
Giardia lamblia Cathepsin B precursor 0.0074 0.0936 0.2334
Trypanosoma brucei metacaspase 5, putative 0.0058 0.0667 0.1276
Plasmodium vivax unspecified product 0.0074 0.0936 0.1814
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.1931 0.1986
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0259 0.3976 0.7705
Loa Loa (eye worm) hypothetical protein 0.0074 0.0936 0.0966
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0074 0.0936 0.1814
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.001 0.5
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0058 0.0667 0.1276
Echinococcus multilocularis caspase 2 0.0058 0.0667 0.0679
Entamoeba histolytica cysteine protease, putative 0.0074 0.0936 0.1798
Toxoplasma gondii cathepsin B 0.0238 0.3641 0.7053
Brugia malayi cathepsin Z-like cysteine proteinase 0.0074 0.0936 0.0957
Loa Loa (eye worm) hypothetical protein 0.0104 0.1421 0.1468
Leishmania major cathepsin L-like protease 0.033 0.5158 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0332 0.0343
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.033 0.5158 1
Echinococcus multilocularis protein patched 0.0042 0.0402 0.0405
Loa Loa (eye worm) heterochromatin protein 1 0.0067 0.082 0.0847
Schistosoma mansoni chromobox protein 0.0067 0.082 0.0838
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.007 0.0863 1
Onchocerca volvulus 0.0259 0.3976 0.7664
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0062 0.0737 0.0751
Trichomonas vaginalis conserved hypothetical protein 0.0058 0.0667 0.1276
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.007 0.0863 0.1674
Entamoeba histolytica cysteine protease, putative 0.0178 0.2648 0.5123
Brugia malayi latrophilin 2 splice variant baaae 0.0134 0.1928 0.1983
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0074 0.0936 0.1798
Trypanosoma cruzi cysteine protease, putative 0.0178 0.2648 0.2727
Loa Loa (eye worm) hypothetical protein 0.018 0.2673 0.276

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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