Detailed information for compound 1804917

Basic information

Technical information
  • TDR Targets ID: 1804917
  • Name: N-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]- 2-iodobenzamide
  • MW: 441.674 | Formula: C15H9ClIN3OS
  • H donors: 1 H acceptors: 3 LogP: 4.47 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(cc1)c1nnc(s1)NC(=O)c1ccccc1I
  • InChi: 1S/C15H9ClIN3OS/c16-10-7-5-9(6-8-10)14-19-20-15(22-14)18-13(21)11-3-1-2-4-12(11)17/h1-8H,(H,18,20,21)
  • InChiKey: MQSPTMAPMSHDLN-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[5-(4-chlorophenyl)-1,3,4-thiadiazol-2-yl]-2-iodo-benzamide
  • Oprea1_649546

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0009 0.0016 0.0000012914
Brugia malayi Latrophilin receptor protein 2 0.0028 0.0257 0.035
Onchocerca volvulus 0.0043 0.0446 0.1814
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0195 0.2387 0.2387
Loa Loa (eye worm) latrophilin receptor protein 2 0.0028 0.0257 0.0349
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0289 0.085
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0021 0.0169 0.0643
Brugia malayi hypothetical protein 0.0009 0.0016 0.0021
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0009 0.0016 0.0059
Trypanosoma cruzi cruzipain precursor, putative 0.0059 0.0655 0.0876
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0108 0.1285 0.1755
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0533 0.0708
Entamoeba histolytica cysteine proteinase 2 0.0108 0.1285 0.5352
Onchocerca volvulus Cathepsin L homolog 0.0049 0.0533 0.2183
Entamoeba histolytica cysteine protease, putative 0.0049 0.0533 0.2183
Onchocerca volvulus 0.0025 0.022 0.0862
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0701 0.8839 0.8839
Brugia malayi CXXC zinc finger family protein 0.0025 0.022 0.03
Echinococcus multilocularis SAM and MBT domain containing protein 0.0043 0.0446 0.0446
Plasmodium vivax vivapain-1 0.0108 0.1285 0.5352
Trichomonas vaginalis ran, putative 0.0019 0.0145 0.055
Echinococcus multilocularis lamin 0.0024 0.021 0.021
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0049 0.0533 0.0728
Schistosoma mansoni hypothetical protein 0.006 0.0667 0.091
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0045 0.0483 0.1174
Loa Loa (eye worm) hypothetical protein 0.0048 0.0521 0.0709
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0009 0.0019 0.0013
Echinococcus granulosus cathepsin l cysteine peptidase 0.0195 0.2387 0.2387
Loa Loa (eye worm) MBCTL1 0.0048 0.0521 0.0709
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0049 0.0533 0.0726
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Giardia lamblia Cathepsin L precursor 0.0049 0.0533 0.1978
Brugia malayi nuclear hormone receptor 0.0009 0.0019 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.2387 0.9067
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0017 0.0117 0.0429
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0019 0.0145 0.0177
Loa Loa (eye worm) hypothetical protein 0.0009 0.0016 0.0019
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0028 0.0257 0.0257
Leishmania major cathepsin L-like protease 0.0195 0.2387 0.729
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0049 0.0533 0.2183
Echinococcus granulosus survival motor neuron protein 1 0.0211 0.2592 0.2592
Echinococcus granulosus cathepsin l1 0.0195 0.2387 0.2387
Loa Loa (eye worm) hypothetical protein 0.0049 0.0533 0.0726
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0017 0.0117 0.0709
Loa Loa (eye worm) hypothetical protein 0.0009 0.0016 0.0019
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0048 0.0521 0.0521
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0009 0.0019 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Trichomonas vaginalis replication factor C large subunit, putative 0.0009 0.0016 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0049 0.0533 0.2025
Echinococcus multilocularis peptidyl glycine alpha amidating monooxygenase 0.0228 0.2812 0.2812
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Schistosoma mansoni survival motor neuron protein 0.0043 0.0452 0.0617
Loa Loa (eye worm) hypothetical protein 0.0136 0.1636 0.2232
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Schistosoma mansoni cpg binding protein 0.0026 0.0238 0.0325
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0019 0.0025
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0009 0.0016 0.0059
Onchocerca volvulus 0.0195 0.2387 1
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0195 0.2387 1
Onchocerca volvulus 0.0195 0.2387 1
Brugia malayi Importin beta-1 subunit 0.0026 0.0231 0.0316
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0533 0.2025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0023
Brugia malayi Cathepsin L-like precursor 0.0195 0.2387 0.326
Brugia malayi fibroinase precursor 0.0049 0.0533 0.0728
Entamoeba histolytica cysteine protease, putative 0.0049 0.0533 0.2183
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0049 0.0533 0.0728
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0009 0.0019 0.0019
Echinococcus granulosus FTZ F1 alpha 0.0009 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0012 0.0052 0.0068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.2387 0.9067
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0028 0.0257 0.035
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0017 0.0117 0.0429
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0088 0.102 0.1391
Echinococcus multilocularis mitogen activated protein kinase 0.0045 0.0483 0.0483
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.2387 0.3246
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0049 0.0533 0.2183
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0195 0.2387 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0023
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0121 0.1448 0.1978
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0019 0.0145 0.0545
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0009 0.0019 0.0023
Giardia lamblia Cathepsin B precursor 0.0214 0.2633 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0582 0.7323 1
Echinococcus multilocularis polycomb protein SCMH1 0.0043 0.0446 0.0446
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0019 0.0145 0.0177
Schistosoma mansoni lamin 0.0024 0.021 0.0287
Brugia malayi Cathepsin L-like precursor 0.0195 0.2387 0.326
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.1285 0.3947
Entamoeba histolytica cysteine proteinase, putative 0.0108 0.1285 0.5352
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0019 0.0019
Onchocerca volvulus 0.0043 0.0452 0.184
Schistosoma mansoni lamin 0.0024 0.021 0.0287
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Loa Loa (eye worm) CXXC zinc finger family protein 0.0025 0.022 0.0298
Brugia malayi Papain family cysteine protease containing protein 0.0108 0.1285 0.1754
Echinococcus granulosus mitogen activated protein kinase 0.0045 0.0483 0.0483
Schistosoma mansoni hypothetical protein 0.0043 0.0452 0.0617
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0017 0.0117 0.043
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0049 0.0533 0.2183
Giardia lamblia Cathepsin L precursor 0.0049 0.0533 0.1978
Loa Loa (eye worm) hypothetical protein 0.0136 0.1636 0.2232
Loa Loa (eye worm) cysteine protease 0.0195 0.2387 0.3259
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.2387 0.3246
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.0228 0.2812 0.384
Loa Loa (eye worm) hypothetical protein 0.0024 0.021 0.0285
Echinococcus multilocularis thyroid hormone receptor alpha 0.0009 0.0019 0.0019
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0261 0.3231 0.4401
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0061
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0049 0.0533 0.2183
Schistosoma mansoni cpg binding protein 0.0026 0.0238 0.0325
Brugia malayi Cathepsin L-like precursor 0.0195 0.2387 0.326
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0195 0.2387 0.9067
Chlamydia trachomatis DNA ligase 0.0009 0.0016 0.5
Brugia malayi Intermediate filament tail domain containing protein 0.0024 0.021 0.0287
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0049 0.0533 0.2183
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0195 0.2387 0.3259
Leishmania major cysteine peptidase A (CPA) 0.0195 0.2387 0.729
Giardia lamblia Cathepsin L precursor 0.0049 0.0533 0.1978
Giardia lamblia Cathepsin L precursor 0.0049 0.0533 0.1978
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0533 0.0728
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0009 0.0019 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0533 0.2025
Echinococcus granulosus SAM and MBT domain containing protein 0.0043 0.0446 0.0446
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0009 0.0019 0.0023
Echinococcus granulosus histone acetyltransferase MYST2 0.0048 0.0521 0.0521
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0483 0.1834
Echinococcus multilocularis dnaJ subfamily B 0.0354 0.4411 0.4411
Echinococcus granulosus dnaJ subfamily B 0.0354 0.4411 0.4411
Onchocerca volvulus 0.0195 0.2387 1
Leishmania major importin beta-1 subunit, putative 0.0021 0.0169 0.0167
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Trypanosoma cruzi cysteine peptidase, putative 0.0108 0.1285 0.1737
Echinococcus granulosus cathepsin L cysteine protease 0.0108 0.1285 0.1285
Giardia lamblia Cathepsin B precursor 0.0049 0.0533 0.1978
Schistosoma mansoni intermediate filament proteins 0.0024 0.021 0.0287
Mycobacterium tuberculosis Conserved hypothetical protein 0.0138 0.1657 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0048 0.0521 0.0521
Treponema pallidum exodeoxyribonuclease (exoA) 0.0017 0.0117 1
Brugia malayi cathepsin Z-like cysteine proteinase 0.0049 0.0533 0.0728
Plasmodium vivax unspecified product 0.0108 0.1285 0.5352
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0049 0.0533 0.1978
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0019 0.0025
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.2387 0.3246
Loa Loa (eye worm) hypothetical protein 0.0121 0.1448 0.1976
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0195 0.2387 0.3259
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0214 0.2633 0.3582
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0043 0.0452 0.0617
Brugia malayi Nuclear hormone receptor-like 1 0.0009 0.0019 0.0025
Echinococcus granulosus cathepsin L 0.0108 0.1285 0.1285
Brugia malayi Papain family cysteine protease containing protein 0.0195 0.2387 0.326
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.003 0.0289 1
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0009 0.0019 0.0019
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0009 0.0016 0.0094
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0028 0.0257 0.0257
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0009 0.0019 0.0019
Onchocerca volvulus 0.0024 0.021 0.0821
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0009 0.0016 0.0625
Echinococcus granulosus cathepsin b 0.0582 0.7323 0.7323
Loa Loa (eye worm) hypothetical protein 0.0106 0.1254 0.171
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0019 0.0145 0.0545
Echinococcus multilocularis cysteine protease 0.0195 0.2387 0.2387
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0533 0.2025
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0195 0.2387 0.9067
Loa Loa (eye worm) hypothetical protein 0.0059 0.0655 0.0893
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.1285 0.488
Brugia malayi follicle stimulating hormone receptor 0.0194 0.2371 0.3238
Loa Loa (eye worm) hypothetical protein 0.0582 0.7323 1
Schistosoma mansoni topbp1 0.0009 0.0016 0.0021
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0533 0.2025
Loa Loa (eye worm) hypothetical protein 0.0049 0.0533 0.0726
Schistosoma mansoni inositol monophosphatase 0.003 0.0289 0.0394
Mycobacterium ulcerans hypothetical protein 0.0138 0.1657 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0214 0.2633 0.814
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0059 0.0655 0.0895
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0017 0.0117 0.0709
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0059
Echinococcus multilocularis cpg binding protein 0.0026 0.0238 0.0238
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0019 0.0145 0.0402
Loa Loa (eye worm) cathepsin B 0.0214 0.2633 0.3594
Plasmodium falciparum serine repeat antigen 7 0.0049 0.0533 0.2183
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0009 0.0019 0.0019
Echinococcus granulosus inositol monophosphatase 1 0.003 0.0289 0.0289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0009 0.0019 0.0023
Echinococcus granulosus peptidyl glycine alpha amidating monooxygenase 0.0228 0.2812 0.2812
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Toxoplasma gondii exonuclease III APE 0.0017 0.0117 0.0389
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0024 0.021 0.0285
Schistosoma mansoni hypothetical protein 0.0028 0.0257 0.0351
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0088 0.102 0.1392
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0019 0.0025
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0483 0.1834
Echinococcus multilocularis cathepsin b 0.0582 0.7323 0.7323
Onchocerca volvulus 0.0195 0.2387 1
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.0117 0.0446
Onchocerca volvulus Huntingtin homolog 0.0106 0.1254 0.5219
Schistosoma mansoni ran 0.0019 0.0145 0.0198
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0136 0.1636 0.6212
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0171 0.2084 0.2084
Echinococcus granulosus cysteine protease 0.0108 0.1285 0.1285
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.003 0.0289 0.1044
Schistosoma mansoni hypothetical protein 0.0028 0.0257 0.0351
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0195 0.2387 0.2387
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0045 0.0483 0.1453
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0049 0.0533 0.2025
Echinococcus multilocularis cathepsin L cysteine protease 0.0195 0.2387 0.2387
Onchocerca volvulus 0.0009 0.0019 0.0013
Schistosoma mansoni RAR-like nuclear receptor 0.0009 0.0019 0.0025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0533 0.0728
Loa Loa (eye worm) mbt repeat family protein 0.0043 0.0446 0.0607
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0533 0.2025
Schistosoma mansoni cathepsin S (C01 family) 0.0049 0.0533 0.0728
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Echinococcus multilocularis GPCR, family 2 0.0028 0.0257 0.0257
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Trypanosoma cruzi importin beta-1 subunit, putative 0.0021 0.0169 0.0211
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Loa Loa (eye worm) fibroinase 0.0195 0.2387 0.3259
Entamoeba histolytica cysteine protease, putative 0.0049 0.0533 0.2183
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0533 0.2025
Plasmodium falciparum cysteine proteinase falcipain 1 0.0108 0.1285 0.5352
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0009 0.0019 0.0019
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.2387 0.9067
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0009 0.0019 0.0019
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0049 0.0533 0.0728
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0009 0.0019 0.0023
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0045 0.0483 0.064
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0483 0.1834
Echinococcus multilocularis replication factor c subunit 1 0.0009 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0023
Entamoeba histolytica hypothetical protein 0.0049 0.0533 0.2183
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0108 0.1285 0.3947
Schistosoma mansoni hypothetical protein 0.0028 0.0257 0.0351
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0045 0.0483 0.064
Giardia lamblia Cysteine protease 0.0049 0.0533 0.1978
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0009 0.0019 0.0019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0533 0.2025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0016 0.0019
Loa Loa (eye worm) hypothetical protein 0.0088 0.102 0.1391
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Brugia malayi cathepsin F-like cysteine proteinase 0.0059 0.0655 0.0895
Echinococcus multilocularis cathepsin L cysteine protease 0.0195 0.2387 0.2387
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0023
Plasmodium falciparum serine repeat antigen 6 0.0049 0.0533 0.2183
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0049 0.0533 0.2183
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0037 0.0372 0.0487
Schistosoma mansoni thyroid hormone receptor 0.0009 0.0019 0.0025
Brugia malayi hypothetical protein 0.0009 0.0016 0.0021
Plasmodium vivax importin-beta 2, putative 0.0026 0.0231 0.091
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0028 0.0257 0.0257
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0049 0.0533 0.1978
Loa Loa (eye worm) hypothetical protein 0.0049 0.0533 0.0726
Echinococcus granulosus neuropeptide receptor A26 0.0792 1 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0046 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0124 0.1479 0.4549
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0533 0.2025
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0017 0.0117 0.0117
Toxoplasma gondii hypothetical protein 0.0042 0.044 0.1623
Schistosoma mansoni sex comb on midleg homolog 0.0043 0.0446 0.0609
Schistosoma mansoni retinoic acid receptor RXR 0.0009 0.0019 0.0025
Toxoplasma gondii cathepsin B 0.0214 0.2633 1
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0049 0.0533 0.2183
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.2387 0.9067
Brugia malayi cathepsin B-like cysteine proteinase 0.0582 0.7323 1
Brugia malayi Papain family cysteine protease containing protein 0.0049 0.0533 0.0728
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0017 0.0117 0.4065
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0108 0.1285 0.1737
Brugia malayi cathepsin L-like cysteine proteinase 0.0049 0.0533 0.0728
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0582 0.7323 1
Trichomonas vaginalis ap endonuclease, putative 0.0017 0.0117 0.0446
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0009 0.0019 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0533 0.2025
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0019 0.0145 0.0494
Plasmodium falciparum serine repeat antigen 1 0.0049 0.0533 0.2183
Schistosoma mansoni peptidyl-glycine monooxygenase 0.0228 0.2812 0.384
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0533 0.2025
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0048 0.0521 0.0521
Echinococcus multilocularis cathepsin L 0.0108 0.1285 0.1285
Echinococcus multilocularis cathepsin b 0.0582 0.7323 0.7323
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0037 0.0372 0.1107
Echinococcus multilocularis lamin dm0 0.0024 0.021 0.021
Brugia malayi Pax transcription activation domain interacting protein 0.0009 0.0016 0.0021
Leishmania major cathepsin L-like protease 0.0195 0.2387 0.729
Schistosoma mansoni cpg binding protein 0.0025 0.022 0.0301
Onchocerca volvulus 0.0049 0.0533 0.2183
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0009 0.0019 0.0025
Echinococcus granulosus snurportin 1 0.0275 0.3403 0.3403
Entamoeba histolytica Ran family GTPase 0.0019 0.0145 0.0545
Brugia malayi MAP kinase sur-1 0.0045 0.0483 0.0659
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0027 0.0248 0.15
Plasmodium falciparum serine repeat antigen 4 0.0049 0.0533 0.2183
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0214 0.2633 1
Schistosoma mansoni hypothetical protein 0.0262 0.3243 0.4429
Wolbachia endosymbiont of Brugia malayi NAD-dependent DNA ligase, Lig 0.0009 0.0016 0.0538
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0261 0.3231 1
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Echinococcus granulosus GPCR family 2 0.0028 0.0257 0.0257
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0009 0.0019 0.0025
Echinococcus multilocularis nibrin 0.0009 0.0016 0.0016
Schistosoma mansoni cathepsin F (C01 family) 0.0195 0.2387 0.326
Echinococcus multilocularis neuropeptide receptor A26 0.0792 1 1
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0289 0.0374
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0533 0.2025
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0049 0.0533 0.2025
Brugia malayi latrophilin 2 splice variant baaae 0.006 0.0667 0.091
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0533 0.0728
Trypanosoma cruzi cysteine peptidase, putative 0.0059 0.0655 0.0876
Plasmodium vivax vivapain-2 0.0195 0.2387 1
Plasmodium vivax serine-repeat antigen (SERA) 0.0049 0.0533 0.2183
Echinococcus granulosus cathepsin L 0.0049 0.0533 0.0533
Entamoeba histolytica hypothetical protein 0.0021 0.0169 0.0649
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0045 0.0483 0.064
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.2387 0.9067
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0289 0.0374
Echinococcus granulosus nibrin 0.0009 0.0016 0.0016
Entamoeba histolytica cysteine protease, putative 0.0049 0.0533 0.2183
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0049 0.0533 0.0726
Plasmodium vivax serine-repeat antigen (SERA) 0.0049 0.0533 0.2183
Loa Loa (eye worm) hypothetical protein 0.0059 0.0655 0.0893
Giardia lamblia Hypothetical protein 0.0049 0.0533 0.1978
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0533 0.2025
Giardia lamblia Cysteine protease 0.0049 0.0533 0.1978
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0048 0.0521 0.0711
Brugia malayi cathepsin L precursor 0.0049 0.0533 0.0728
Entamoeba histolytica cysteine proteinase, putative 0.0136 0.1636 0.6831
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0017 0.0117 0.0317
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Echinococcus multilocularis importin subunit beta 1 0.0026 0.0231 0.0231
Echinococcus granulosus importin subunit beta 1 0.0026 0.0231 0.0231
Leishmania major cathepsin L-like protease 0.0195 0.2387 0.729
Toxoplasma gondii ATPase, AAA family protein 0.0009 0.0016 0.0000011702
Giardia lamblia Cathepsin L precursor 0.0049 0.0533 0.1978
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0136 0.1636 0.6212
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0108 0.1285 0.1755
Echinococcus granulosus mitogen activated protein kinase 3 0.0045 0.0483 0.0483
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0009 0.0019 0.0025
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0124 0.1479 0.2002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0009 0.0019 0.0025
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0049 0.0533 0.2025
Loa Loa (eye worm) hypothetical protein 0.0009 0.0016 0.0019
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0009 0.0019 0.0025
Entamoeba histolytica cysteine protease, putative 0.0195 0.2387 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0009 0.0016 0.0059
Brugia malayi cytoplasmic intermediate filament protein 0.0013 0.0068 0.0092
Loa Loa (eye worm) ctsf protein 0.0195 0.2387 0.3259
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0019 0.0145 0.0494
Schistosoma mansoni peptidylglycine monooxygenase 0.0121 0.1448 0.1978
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.2387 0.9067
Trypanosoma brucei importin beta-1 subunit, putative 0.0026 0.0231 0.0671
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0049 0.0533 0.2183
Brugia malayi Cathepsin L-like precursor 0.0059 0.0655 0.0895
Echinococcus multilocularis snurportin 1 0.0275 0.3403 0.3403
Entamoeba histolytica cysteine proteinase 1, putative 0.0108 0.1285 0.5352
Leishmania major mitochondrial DNA polymerase beta 0.0261 0.3231 1
Plasmodium vivax unspecified product 0.0049 0.0533 0.2183
Trypanosoma cruzi cysteine proteinase, putative 0.0108 0.1285 0.1737
Echinococcus multilocularis mitogen activated protein kinase 3 0.0045 0.0483 0.0483
Leishmania major cathepsin L-like protease 0.0195 0.2387 0.729
Brugia malayi cathepsin F-like cysteine proteinase 0.0049 0.0533 0.0728
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0023
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0049 0.0533 0.0728
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0017 0.0117 0.0117
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0108 0.1285 0.1755
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0108 0.1285 0.488
Trypanosoma cruzi cysteine peptidase, putative 0.0195 0.2387 0.3246
Schistosoma mansoni hypothetical protein 0.0354 0.4411 0.6023
Loa Loa (eye worm) hypothetical protein 0.0106 0.1254 0.171
Onchocerca volvulus Cathepsin F homolog 0.0195 0.2387 1
Toxoplasma gondii preprocathepsin c precursor, putative 0.0049 0.0533 0.1978
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0049 0.0533 0.2183
Giardia lamblia Kinase, CMGC MAPK 0.0045 0.0483 0.1785
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0037 0.0372 0.0487
Entamoeba histolytica cysteine proteinase, putative 0.0195 0.2387 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0214 0.2633 0.8079
Schistosoma mansoni ran 0.0019 0.0145 0.0198
Treponema pallidum DNA ligase (lig) 0.0009 0.0016 0.1324
Schistosoma mansoni cathepsin s 0.0059 0.0655 0.0895
Brugia malayi exodeoxyribonuclease III family protein 0.0017 0.0117 0.016
Schistosoma mansoni sex comb on midleg homolog 0.0043 0.0446 0.0609
Brugia malayi Cathepsin L-like precursor 0.0195 0.2387 0.326
Brugia malayi Inositol-1 0.003 0.0289 0.0394
Plasmodium falciparum serine repeat antigen 5 0.0049 0.0533 0.2183
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0009 0.0019 0.0025
Echinococcus granulosus GTP binding nuclear protein Ran 0.0019 0.0145 0.0145
Plasmodium falciparum importin beta, putative 0.0026 0.0231 0.091
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0009 0.0016 0.0021
Echinococcus granulosus cathepsin b 0.0582 0.7323 0.7323
Trichomonas vaginalis CMGC family protein kinase 0.0045 0.0483 0.1834
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0019 0.0025
Schistosoma mansoni dopamine-beta-monooxygenase 0.0121 0.1448 0.1978
Brugia malayi cathepsin Z-like cysteine proteinase 0.0049 0.0533 0.0728
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0136 0.1636 0.2217
Plasmodium falciparum serine repeat antigen 9 0.0049 0.0533 0.2183
Trypanosoma cruzi cysteine proteinase, putative 0.0108 0.1285 0.1737
Echinococcus granulosus cathepsin L cysteine proteinase 0.0195 0.2387 0.2387
Entamoeba histolytica cysteine proteinase, putative 0.0195 0.2387 1
Echinococcus granulosus lamin dm0 0.0024 0.021 0.021
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0037 0.0372 0.0487
Echinococcus multilocularis FTZ F1 alpha 0.0009 0.0019 0.0019
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.003 0.0289 0.1744
Echinococcus granulosus cathepsin l1 0.0136 0.1636 0.1636
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0009 0.0019 0.0019
Brugia malayi Steroid receptor seven-up type 2 0.0009 0.0019 0.0025
Brugia malayi Papain family cysteine protease containing protein 0.0108 0.1285 0.1754
Toxoplasma gondii cathepsin CPL 0.0195 0.2387 0.9061
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Leishmania major GTP-binding protein, putative 0.0019 0.0145 0.0088
Schistosoma mansoni importin beta-1 0.0026 0.0231 0.0316
Toxoplasma gondii cathepsin CPC1 0.0049 0.0533 0.1978
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0049 0.0533 0.1978
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.2387 0.9067
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0009 0.0019 0.0019
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0019 0.0019
Brugia malayi Cathepsin L-like precursor 0.0136 0.1636 0.2233
Trypanosoma brucei importin beta-1 subunit, putative 0.0026 0.0231 0.0671
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0533 0.0708
Loa Loa (eye worm) inositol-1 0.003 0.0289 0.0392
Echinococcus granulosus polycomb protein SCMH1 0.0043 0.0446 0.0446
Trypanosoma brucei protein kinase, putative 0.0045 0.0483 0.1453
Loa Loa (eye worm) hypothetical protein 0.006 0.0667 0.0908
Giardia lamblia Cathepsin B precursor 0.0049 0.0533 0.1978
Entamoeba histolytica cysteine proteinase, putative 0.0108 0.1285 0.5352
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0059
Giardia lamblia Cathepsin B precursor 0.0214 0.2633 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0009 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0028 0.0257 0.0351
Loa Loa (eye worm) hypothetical protein 0.0043 0.0446 0.0607
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0214 0.2633 0.3596
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0194 0.2371 0.3236
Giardia lamblia Hypothetical protein 0.0049 0.0533 0.1978
Loa Loa (eye worm) hypothetical protein 0.0059 0.0655 0.0893
Echinococcus multilocularis survival motor neuron protein 1 0.0211 0.2592 0.2592
Echinococcus granulosus cpg binding protein 0.0026 0.0238 0.0238
Entamoeba histolytica myo-inositol monophosphatase, putative 0.003 0.0289 0.1152
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0002 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0049 0.0533 0.2183
Echinococcus multilocularis neuropeptide s receptor 0.0792 1 1
Loa Loa (eye worm) hypothetical protein 0.0028 0.0257 0.0349
Loa Loa (eye worm) hypothetical protein 0.0009 0.0016 0.0019
Brugia malayi Copper type II ascorbate-dependent monooxygenase, C-terminal domain containing protein 0.006 0.0664 0.0907
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0012 0.0052 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0195 0.2387 0.7376
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0009 0.0019 0.0025
Plasmodium falciparum serine repeat antigen 8 0.0049 0.0533 0.2183
Loa Loa (eye worm) hypothetical protein 0.0009 0.0016 0.0019
Giardia lamblia Cathepsin L-like protease 0.0049 0.0533 0.1978
Loa Loa (eye worm) hypothetical protein 0.0026 0.0231 0.0314
Schistosoma mansoni ap endonuclease 0.0017 0.0117 0.016
Brugia malayi hypothetical protein 0.0211 0.2592 0.3539
Brugia malayi cathepsin L-like precursor 0.0136 0.1636 0.2233
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0009 0.0019 0.0025
Onchocerca volvulus 0.0136 0.1636 0.6831
Leishmania major cathepsin L-like protease 0.0195 0.2387 0.729
Entamoeba histolytica cysteine proteinase, putative 0.0108 0.1285 0.5352
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0019 0.0145 0.0145
Schistosoma mansoni cathepsin F (C01 family) 0.0195 0.2387 0.326
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0582 0.7323 1
Brugia malayi hypothetical protein 0.0106 0.1254 0.1711
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0045 0.0483 0.0657
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0045 0.0483 0.1785
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0023
Onchocerca volvulus Bile acid receptor homolog 0.0009 0.0019 0.0013
Schistosoma mansoni ap endonuclease 0.0017 0.0117 0.016
Leishmania major cathepsin L-like protease 0.0195 0.2387 0.729
Onchocerca volvulus 0.0195 0.2387 1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0049 0.0533 0.2183
Leishmania major cathepsin L-like protease 0.0195 0.2387 0.729
Schistosoma mansoni topbp1 0.0009 0.0016 0.0021
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0275 0.3403 0.4646
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Brugia malayi Cathepsin L-like precursor 0.0136 0.1636 0.2233
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0019 0.0145 0.0197
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0009 0.0019 0.0025
Onchocerca volvulus 0.0024 0.021 0.0821
Trichomonas vaginalis importin beta-1, putative 0.0021 0.0169 0.0643
Schistosoma mansoni DNA ligase IV 0.0009 0.0016 0.0021
Toxoplasma gondii cathepsin CPC2 0.0049 0.0533 0.1978
Brugia malayi mbt repeat family protein 0.0043 0.0446 0.0608
Brugia malayi Cathepsin L-like cysteine proteinase 0.0136 0.1636 0.2233
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.0289 0.0551
Echinococcus multilocularis inositol monophosphatase 1 0.003 0.0289 0.0289
Plasmodium vivax vivapain-2 0.0195 0.2387 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0533 0.0726
Toxoplasma gondii HEAT repeat-containing protein 0.0026 0.0231 0.0825
Loa Loa (eye worm) hypothetical protein 0.0049 0.0533 0.0726
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0043 0.0446 0.1814
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0049 0.0533 0.0728
Toxoplasma gondii histone lysine methyltransferase SET1 0.0047 0.0503 0.1863
Brugia malayi Papain family cysteine protease containing protein 0.0049 0.0533 0.0728
Trypanosoma cruzi cysteine protease, putative 0.0108 0.1285 0.1737
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0009 0.0019 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.2387 0.9067
Schistosoma mansoni cathepsin F (C01 family) 0.0136 0.1636 0.2234
Entamoeba histolytica cysteine protease, putative 0.0049 0.0533 0.2183
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0045 0.0483 0.064
Brugia malayi topoisomerase 0.0009 0.0016 0.0021
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0049 0.0533 0.2183
Plasmodium falciparum serine repeat antigen 3 0.0049 0.0533 0.2183
Schistosoma mansoni steroid hormone receptor ad4bp 0.0009 0.0019 0.0025
Plasmodium falciparum cysteine proteinase falcipain 3 0.0195 0.2387 1
Entamoeba histolytica cysteine protease, putative 0.0108 0.1285 0.5352
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0059 0.0655 0.0893
Echinococcus granulosus intermediate filament protein 0.0024 0.021 0.021
Onchocerca volvulus Cathepsin L homolog 0.0195 0.2387 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0045 0.0483 0.1174
Giardia lamblia Cysteine protease 0.0049 0.0533 0.1978
Trypanosoma cruzi cruzipain precursor, putative 0.0195 0.2387 0.3246
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0013 0.0068 0.0091
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0124 0.1479 0.4371
Brugia malayi steroid hormone receptor 0.0009 0.0019 0.0025
Echinococcus multilocularis cathepsin L 0.0049 0.0533 0.0533
Brugia malayi intermediate filament protein 0.0024 0.021 0.0287
Entamoeba histolytica cysteine protease, putative 0.0049 0.0533 0.2183
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0017 0.0117 0.0139
Brugia malayi mbt repeat family protein 0.0043 0.0446 0.0608
Brugia malayi photoreceptor-specific nuclear receptor 0.0009 0.0019 0.0025
Onchocerca volvulus 0.0195 0.2387 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0049 0.0533 0.2183
Echinococcus multilocularis ecdysone induced protein 78C 0.0009 0.0019 0.0019
Echinococcus granulosus lamin 0.0024 0.021 0.021
Schistosoma mansoni inositol monophosphatase 0.003 0.0289 0.0394
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0043 0.0446 0.0609
Schistosoma mansoni cathepsin C 0.0049 0.0533 0.0728
Loa Loa (eye worm) hypothetical protein 0.0136 0.1636 0.2232
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0009 0.0019 0.0023
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0009 0.0019 0.0025
Schistosoma mansoni myelin transcription factor 1 myt1 0.0048 0.0521 0.0711
Onchocerca volvulus 0.0195 0.2387 1
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0028 0.0257 0.0257
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0582 0.7323 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0533 0.0728
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0009 0.0019 0.0025
Brugia malayi Cathepsin L-like precursor 0.0195 0.2387 0.326
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0009 0.0019 0.0025
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0017 0.0117 0.0158
Plasmodium vivax unspecified product 0.0059 0.0655 0.2697
Schistosoma mansoni nuclear hormone receptor 0.0009 0.0019 0.0025
Loa Loa (eye worm) hypothetical protein 0.0228 0.2812 0.3839
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0009 0.0016 0.0059
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0049 0.0533 0.0728
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0023
Brugia malayi RNA, U transporter 1 0.0073 0.0836 0.1141
Brugia malayi Calcitonin receptor-like protein seb-1 0.0088 0.102 0.1392
Echinococcus multilocularis musashi 0.0024 0.021 0.021
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0017 0.0117 0.0139
Loa Loa (eye worm) hypothetical protein 0.0009 0.0019 0.0023
Loa Loa (eye worm) intermediate filament protein 0.0024 0.021 0.0285
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0027 0.0248 1
Entamoeba histolytica cysteine proteinase, putative 0.0108 0.1285 0.5352
Trichomonas vaginalis myo inositol monophosphatase, putative 0.003 0.0289 0.1097
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0049 0.0533 0.2183
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0059
Schistosoma mansoni serine/threonine protein kinase 0.0045 0.0483 0.0659
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0012 0.0052 0.0052
Trichomonas vaginalis myo inositol monophosphatase, putative 0.003 0.0289 0.1097
Brugia malayi nuclear receptor NHR-88 0.0009 0.0019 0.0025
Brugia malayi Papain family cysteine protease containing protein 0.0049 0.0533 0.0728
Brugia malayi DKFZp564C0469 protein 0.0009 0.0016 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0059
Giardia lamblia Encystation-specific protease 0.0049 0.0533 0.1978
Plasmodium vivax vivapain-3 0.0108 0.1285 0.5352
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0195 0.2387 0.9067
Giardia lamblia Cathepsin L-like protease 0.0049 0.0533 0.1978
Onchocerca volvulus Cathepsin L homolog 0.0195 0.2387 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0009 0.0019 0.0019
Onchocerca volvulus Huntingtin homolog 0.0106 0.1254 0.5219
Giardia lamblia Cathepsin B precursor 0.0049 0.0533 0.1978
Loa Loa (eye worm) hypothetical protein 0.0049 0.0533 0.0726
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0195 0.2387 0.9067
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0049 0.0533 0.0726
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0049 0.0533 0.2025
Loa Loa (eye worm) hypothetical protein 0.0195 0.2387 0.3259
Giardia lamblia Cysteine protease 0.0049 0.0533 0.1978
Brugia malayi ecdysteroid receptor 0.0009 0.0019 0.0025
Brugia malayi Copper type II ascorbate-dependent monooxygenase, N-terminal domain containing protein 0.0062 0.0688 0.0939
Echinococcus granulosus replication factor c subunit 1 0.0009 0.0016 0.0016
Schistosoma mansoni chromosome transmission fidelity factor 0.0009 0.0016 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0009 0.0016 0.0059
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0049 0.0533 0.2025
Schistosoma mansoni cathepsin B (C01 family) 0.0049 0.0533 0.0728
Onchocerca volvulus Protein ultraspiracle homolog 0.0009 0.0019 0.0013
Schistosoma mansoni hypothetical protein 0.0275 0.3403 0.4647
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0009 0.0019 0.0023
Giardia lamblia Cathepsin L precursor 0.0049 0.0533 0.1978
Echinococcus granulosus ecdysone induced protein 78C 0.0009 0.0019 0.0019
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0053 0.0575 0.0785
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0017 0.0117 0.0389
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0261 0.3231 0.4401
Brugia malayi Cathepsin L-like precursor 0.0195 0.2387 0.326
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0171 0.2084 0.2084
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0049 0.0533 0.2025
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0009 0.0019 0.0023
Giardia lamblia Cathepsin B precursor 0.0049 0.0533 0.1978
Plasmodium falciparum serine repeat antigen 2 0.0049 0.0533 0.2183
Loa Loa (eye worm) hypothetical protein 0.0211 0.2592 0.3538
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0019 0.0145 0.0196
Loa Loa (eye worm) steroid hormone receptor 0.0009 0.0019 0.0023
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0049 0.0533 0.2183
Echinococcus multilocularis cysteine protease 0.0195 0.2387 0.2387
Loa Loa (eye worm) hypothetical protein 0.0024 0.0205 0.0277
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0582 0.7323 1
Leishmania major cathepsin L-like protease 0.0195 0.2387 0.729
Giardia lamblia Cathepsin B precursor 0.0049 0.0533 0.1978
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0021 0.0169 0.0643
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0045 0.0474 0.0627
Giardia lamblia Cathepsin B precursor 0.0214 0.2633 1
Schistosoma mansoni coup transcription factor 0.0009 0.0019 0.0025
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0049 0.0533 0.1978
Trichomonas vaginalis inositol monophosphatase, putative 0.003 0.0289 0.1097

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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