Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0143 | 0.0479 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0207 | 0.1472 | 0.1316 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0207 | 0.1472 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.1472 | 0.5672 |
Trypanosoma brucei | beta lactamase | 0.0073 | 0.045 | 0.2675 |
Trichomonas vaginalis | importin beta-1, putative | 0.0027 | 0.0095 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0123 | 0.0473 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0017 | 0.0067 |
Mycobacterium ulcerans | bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 | 0.0514 | 0.3818 | 0.5583 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0033 | 0.0143 | 0.0537 |
Brugia malayi | ephrin receptor 1 precursor | 0.0059 | 0.0342 | 0.1481 |
Schistosoma mansoni | tyrosine kinase | 0.0304 | 0.2214 | 0.852 |
Wolbachia endosymbiont of Brugia malayi | cell division protein FtsI | 0.0787 | 0.5907 | 1 |
Loa Loa (eye worm) | TK/EPH protein kinase | 0.0153 | 0.1058 | 0.4076 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0031 | 0.0127 | 0.0504 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0207 | 0.1472 | 0.5665 |
Schistosoma mansoni | ankyrin 23/unc44 | 0.0017 | 0.0016 | 0.000000028407 |
Mycobacterium ulcerans | beta-lactamase | 0.0207 | 0.1472 | 0.1949 |
Echinococcus multilocularis | insulin receptor | 0.0099 | 0.0645 | 0.2473 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0095 | 0.137 |
Mycobacterium leprae | PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSEN | 0.0514 | 0.3818 | 0.5929 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.0043 | 0.0215 | 0.0904 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0127 | 0.0489 |
Brugia malayi | beta-lactamase family protein | 0.0207 | 0.1472 | 0.6626 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0143 | 0.0552 |
Echinococcus multilocularis | netrin receptor unc 5 | 0.0021 | 0.0047 | 0.0164 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0304 | 0.2214 | 0.8527 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0354 | 0.2596 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0014 | 0.0055 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0043 | 0.0215 | 0.0992 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0207 | 0.1472 | 0.5672 |
Mycobacterium ulcerans | penicillin-binding membrane protein PbpB | 0.0784 | 0.5887 | 0.879 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.0043 | 0.0215 | 0.0992 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.0043 | 0.0215 | 0.0647 |
Echinococcus granulosus | intermediate filament protein | 0.0031 | 0.0127 | 0.0376 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0164 | 0.1147 | 0.3508 |
Brugia malayi | Importin beta-1 subunit | 0.0033 | 0.0143 | 0.0578 |
Echinococcus multilocularis | musashi | 0.0031 | 0.0127 | 0.0473 |
Echinococcus granulosus | nuclear factor of activated T cells 5 | 0.0085 | 0.0537 | 0.1636 |
Schistosoma mansoni | tyrosine kinase | 0.016 | 0.1116 | 0.4262 |
Schistosoma mansoni | tyrosine kinase | 0.0099 | 0.0645 | 0.2438 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0207 | 0.1472 | 0.1316 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0099 | 0.0645 | 0.2485 |
Onchocerca volvulus | 0.0031 | 0.0127 | 0.076 | |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.0043 | 0.0215 | 0.0647 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0164 | 0.1147 | 0.441 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0033 | 0.0143 | 0.0479 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0304 | 0.2214 | 0.6783 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0095 | 0.003 |
Mycobacterium tuberculosis | Conserved protein | 0.0207 | 0.1472 | 0.1316 |
Mycobacterium ulcerans | multidrugs-transport integral membrane protein Mmr-like | 0.0886 | 0.6668 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0042 | 0.0215 | 0.0645 |
Echinococcus multilocularis | lamin | 0.0031 | 0.0127 | 0.0473 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0017 | 0.0005 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.1472 | 0.5672 |
Mycobacterium leprae | PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE | 0.084 | 0.6316 | 1 |
Echinococcus multilocularis | ephrin type A receptor 4 A | 0.0121 | 0.0813 | 0.3122 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.002 | 0.0046 | 0.0134 |
Chlamydia trachomatis | transglycolase/transpeptidase | 0.0787 | 0.5907 | 1 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0207 | 0.1472 | 0.1949 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0344 | 0.1325 |
Schistosoma mansoni | ran | 0.0024 | 0.0076 | 0.0233 |
Schistosoma mansoni | tyrosine kinase | 0.0164 | 0.1147 | 0.4384 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0103 | 0.0679 | 0.207 |
Echinococcus multilocularis | nuclear factor of activated T cells 5 | 0.0085 | 0.0537 | 0.2056 |
Brugia malayi | beta-lactamase | 0.0207 | 0.1472 | 0.6626 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.0043 | 0.0215 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0014 | 0.0055 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0215 | 0.0222 |
Schistosoma mansoni | importin beta-1 | 0.0033 | 0.0143 | 0.0493 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.0043 | 0.0215 | 0.0813 |
Mycobacterium ulcerans | lipoprotein LpqF | 0.0073 | 0.045 | 0.0365 |
Onchocerca volvulus | 0.0207 | 0.1472 | 1 | |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0043 | 0.0215 | 0.0222 |
Plasmodium vivax | importin-beta 2, putative | 0.0033 | 0.0143 | 0.0479 |
Brugia malayi | Inositol-1 | 0.0042 | 0.0215 | 0.0902 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0215 | 0.0828 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.0043 | 0.0215 | 0.077 |
Mycobacterium tuberculosis | Conserved protein | 0.0207 | 0.1472 | 0.1316 |
Echinococcus multilocularis | 0.0093 | 0.0604 | 0.2312 | |
Loa Loa (eye worm) | inositol-1 | 0.0042 | 0.0215 | 0.0827 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0004 | 0.0017 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0207 | 0.1472 | 0.1316 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.0043 | 0.0215 | 0.077 |
Echinococcus multilocularis | Ankyrin | 0.0017 | 0.0017 | 0.005 |
Schistosoma mansoni | cell adhesion molecule | 0.0021 | 0.0048 | 0.0123 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0017 | 0.0017 | 0.0005 |
Mycobacterium tuberculosis | Class a beta-lactamase BlaC | 0.0153 | 0.1056 | 0.0892 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0016 | 0.0014 | 0.0031 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0207 | 0.1472 | 0.1316 |
Leishmania major | importin beta-1 subunit, putative | 0.0027 | 0.0095 | 0.0136 |
Plasmodium vivax | hypothetical protein, conserved | 0.0207 | 0.1472 | 1 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0017 | 0.0016 | 0.0063 |
Mycobacterium tuberculosis | Probable bifunctional penicillin-binding protein 1A/1B PonA1 (murein polymerase) (PBP1): penicillin-insensitive transglycosylase | 0.0327 | 0.2388 | 0.2248 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.1379 | 0.5285 |
Echinococcus granulosus | macrophage colony stimulating factor 1 receptor | 0.0441 | 0.3262 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.0215 | 0.0769 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.1472 | 0.5672 |
Mycobacterium ulcerans | penicillin-binding lipoprotein | 0.0205 | 0.1459 | 0.1928 |
Echinococcus granulosus | netrin receptor unc 5 | 0.0021 | 0.0047 | 0.0131 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0207 | 0.1472 | 0.1316 |
Echinococcus granulosus | insulin receptor | 0.0099 | 0.0645 | 0.1967 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0304 | 0.2214 | 1 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0304 | 0.2214 | 0.8529 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0207 | 0.1472 | 0.2237 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqF | 0.0073 | 0.045 | 0.0274 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0017 | 0.0017 | 0.0005 |
Toxoplasma gondii | ABC1 family protein | 0.0207 | 0.1472 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.0215 | 0.0221 |
Mycobacterium ulcerans | bifunctional penicillin-binding protein 1A/1B PonA1 | 0.084 | 0.6316 | 0.9454 |
Loa Loa (eye worm) | intermediate filament protein | 0.0031 | 0.0127 | 0.0489 |
Echinococcus multilocularis | ankyrin repeat and death domain containing protein | 0.0017 | 0.0016 | 0.0046 |
Mycobacterium leprae | Probable penicillin-binding membrane protein PbpB | 0.0262 | 0.1892 | 0.2789 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0207 | 0.1472 | 0.5645 |
Schistosoma mansoni | tyrosine kinase | 0.016 | 0.1116 | 0.4262 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0042 | 0.0215 | 0.099 |
Echinococcus granulosus | geminin | 0.0195 | 0.1379 | 0.4221 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0017 | 0.0067 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0042 | 0.0215 | 0.0811 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0017 | 0.0017 | 0.0065 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0207 | 0.1472 | 0.2237 |
Onchocerca volvulus | 0.0117 | 0.0782 | 0.5258 | |
Plasmodium falciparum | importin beta, putative | 0.0033 | 0.0143 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0021 | 0.0047 | 0.0139 |
Mycobacterium tuberculosis | Probable penicillin-binding membrane protein PbpB | 0.0262 | 0.1892 | 0.1743 |
Echinococcus granulosus | roundabout 2 | 0.0021 | 0.0048 | 0.0134 |
Schistosoma mansoni | hypothetical protein | 0.0354 | 0.2596 | 1 |
Echinococcus granulosus | Ankyrin | 0.0017 | 0.0017 | 0.004 |
Mycobacterium tuberculosis | Conserved protein | 0.0207 | 0.1472 | 0.1316 |
Echinococcus multilocularis | geminin | 0.0195 | 0.1379 | 0.5306 |
Onchocerca volvulus | 0.0207 | 0.1472 | 1 | |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0095 | 0.003 |
Schistosoma mansoni | hypothetical protein | 0.0195 | 0.1379 | 0.5285 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.0043 | 0.0215 | 0.0992 |
Schistosoma mansoni | tyrosine kinase | 0.0164 | 0.1147 | 0.4384 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0215 | 0.099 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.0043 | 0.0215 | 1 |
Schistosoma mansoni | retinoblastoma-binding protein 4 (rbbp4) | 0.0017 | 0.0017 | 0.0004 |
Trichomonas vaginalis | esterase, putative | 0.0207 | 0.1472 | 0.2237 |
Echinococcus granulosus | ankyrin repeat and death domain containing protein | 0.0017 | 0.0016 | 0.0037 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0215 | 0.099 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0076 | 0.0295 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0215 | 0.099 |
Echinococcus multilocularis | snurportin 1 | 0.0354 | 0.2596 | 1 |
Mycobacterium tuberculosis | Probable bifunctional membrane-associated penicillin-binding protein 1A/1B PonA2 (murein polymerase) [includes: penicillin-insen | 0.0514 | 0.3818 | 0.3704 |
Trichomonas vaginalis | conserved hypothetical protein | 0.084 | 0.6316 | 1 |
Schistosoma mansoni | lamin | 0.0031 | 0.0127 | 0.0429 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0207 | 0.1472 | 0.5645 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0215 | 0.099 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.0043 | 0.0215 | 0.0813 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.0215 | 0.0769 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0207 | 0.1472 | 0.2237 |
Schistosoma mansoni | ephrin receptor | 0.0121 | 0.0813 | 0.309 |
Echinococcus granulosus | lamin dm0 | 0.0031 | 0.0127 | 0.0376 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.1472 | 0.5672 |
Schistosoma mansoni | tyrosine kinase | 0.0099 | 0.0645 | 0.2438 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0031 | 0.0127 | 0.0489 |
Schistosoma mansoni | ran | 0.0024 | 0.0076 | 0.0233 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.1472 | 0.5672 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0207 | 0.1472 | 0.1949 |
Treponema pallidum | penicillin-binding protein (pbp-1) | 0.0787 | 0.5907 | 0.0472 |
Onchocerca volvulus | 0.0031 | 0.0127 | 0.076 | |
Echinococcus granulosus | importin subunit beta 1 | 0.0033 | 0.0143 | 0.0427 |
Echinococcus multilocularis | lamin dm0 | 0.0031 | 0.0127 | 0.0473 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0014 | 0.0055 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQF | 0.0073 | 0.045 | 0.0439 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.0043 | 0.0215 | 0.0992 |
Schistosoma mansoni | lamin | 0.0031 | 0.0127 | 0.0429 |
Mycobacterium ulcerans | class a beta-lactamase, BlaC | 0.0153 | 0.1056 | 0.1305 |
Brugia malayi | beta-lactamase family protein | 0.0207 | 0.1472 | 0.6626 |
Brugia malayi | RNA, U transporter 1 | 0.0094 | 0.0611 | 0.2705 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0103 | 0.0679 | 0.2602 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.0215 | 0.0221 |
Echinococcus granulosus | lamin | 0.0031 | 0.0127 | 0.0376 |
Mycobacterium ulcerans | hypothetical protein | 0.0207 | 0.1472 | 0.1949 |
Mycobacterium leprae | Probable lipase LipE | 0.0207 | 0.1472 | 0.2106 |
Echinococcus granulosus | snurportin 1 | 0.0354 | 0.2596 | 0.7955 |
Brugia malayi | intermediate filament protein | 0.0031 | 0.0127 | 0.0504 |
Mycobacterium leprae | POSSIBLE PENICILLIN-BINDING LIPOPROTEIN | 0.0205 | 0.1459 | 0.2083 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0207 | 0.1472 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.016 | 0.1116 | 0.4262 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0024 | 0.0076 | 0.0221 |
Echinococcus granulosus | death domain containing protein | 0.0017 | 0.0016 | 0.0037 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.0043 | 0.0215 | 0.0813 |
Mycobacterium ulcerans | lipase LipD | 0.0207 | 0.1472 | 0.1949 |
Loa Loa (eye worm) | beta-lactamase | 0.0207 | 0.1472 | 0.5672 |
Mycobacterium leprae | Probable penicillin-binding protein PbpA | 0.047 | 0.3481 | 0.5379 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.002 | 0.0046 | 0.0177 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0017 | 0.0017 | 0.0003 |
Echinococcus multilocularis | roundabout 2 | 0.0021 | 0.0048 | 0.0168 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0207 | 0.1472 | 0.1316 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0207 | 0.1472 | 0.6626 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0027 | 0.0095 | 0.0136 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0207 | 0.1472 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0016 | 0.0063 |
Echinococcus granulosus | ephrin type A receptor 4 A | 0.0121 | 0.0813 | 0.2483 |
Onchocerca volvulus | 0.0207 | 0.1472 | 1 | |
Mycobacterium tuberculosis | Probable penicillin-binding protein PbpA | 0.047 | 0.3481 | 0.3361 |
Mycobacterium ulcerans | multidrug-transport integral membrane protein Mmr | 0.0223 | 0.1597 | 0.2142 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0164 | 0.1147 | 0.3508 |
Mycobacterium leprae | conserved hypothetical protein | 0.0207 | 0.1472 | 0.2106 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.0043 | 0.0215 | 0.0647 |
Loa Loa (eye worm) | hypothetical protein | 0.0117 | 0.0782 | 0.3012 |
Brugia malayi | Protein kinase domain containing protein | 0.0099 | 0.0645 | 0.2861 |
Loa Loa (eye worm) | hypothetical protein | 0.0207 | 0.1472 | 0.5672 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0017 | 0.0067 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0207 | 0.1472 | 0.2237 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0207 | 0.1472 | 0.2237 |
Mycobacterium tuberculosis | Possible penicillin-binding lipoprotein | 0.0205 | 0.1459 | 0.1302 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0207 | 0.1472 | 0.4506 |
Schistosoma mansoni | netrin receptor unc5 | 0.0021 | 0.0047 | 0.0119 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0024 | 0.0076 | 0.0278 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0033 | 0.0143 | 0.0479 |
Mycobacterium ulcerans | penicillin-binding protein PbpA | 0.047 | 0.3481 | 0.5061 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0042 | 0.0215 | 0.9972 |
Schistosoma mansoni | intermediate filament proteins | 0.0031 | 0.0127 | 0.0429 |
Leishmania major | hypothetical protein, conserved | 0.0207 | 0.1472 | 1 |
Treponema pallidum | penicillin-binding protein (pbp-2) | 0.084 | 0.6316 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0042 | 0.0215 | 0.0221 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.0043 | 0.0215 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0017 | 0.0067 |
Schistosoma mansoni | nephrin | 0.0017 | 0.0017 | 0.0004 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0024 | 0.0076 | 0.0274 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0207 | 0.1472 | 0.1316 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI (functional) | = 99 % | Antituberculosis activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition after 12 to 28 days by L-J MIC method | LITERATURE. | No reference |
IZ (functional) | = 23 mm | Antimicrobial activity against Escherichia coli MTCC 739 assessed as diameter of growth inhibition zone after 24 hr by paper disk diffusion technique | ChEMBL. | No reference |
IZ (functional) | = 24 mm | Antimicrobial activity against Candida albicans MTCC 183 assessed as diameter of growth inhibition zone after 24 hr by paper disk diffusion technique | ChEMBL. | No reference |
MIC (functional) | = 12.5 ug ml-1 | Antituberculosis activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition after 12 to 28 days by L-J MIC method | LITERATURE. | No reference |
MIC (functional) | = 25 ug ml-1 | Antimicrobial activity against Candida albicans MTCC 183 assessed as growth inhibition after 48 hr by agar streak dilution technique | ChEMBL. | No reference |
MIC (functional) | = 25 ug ml-1 | Antimicrobial activity against Escherichia coli MTCC 739 assessed as growth inhibition after 24 hr by agar streak dilution technique | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.