Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | threonine--tRNA ligase, putative | 0.0057 | 0.8494 | 1 |
Chlamydia trachomatis | threonine--tRNA ligase | 0.0065 | 1 | 1 |
Mycobacterium leprae | Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) | 0.0057 | 0.8494 | 1 |
Echinococcus multilocularis | Threonyl tRNA synthetase, C | 0.0065 | 1 | 1 |
Mycobacterium tuberculosis | Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) | 0.0057 | 0.8494 | 0.5 |
Trypanosoma brucei | threonyl-tRNA synthetase, putative | 0.0065 | 1 | 1 |
Giardia lamblia | Threonyl-tRNA synthetase | 0.0057 | 0.8494 | 1 |
Schistosoma mansoni | threonyl-tRNA synthetase | 0.0052 | 0.7416 | 1 |
Leishmania major | threonyl-tRNA synthetase, putative | 0.0065 | 1 | 1 |
Trypanosoma cruzi | threonyl-tRNA synthetase, putative | 0.0065 | 1 | 1 |
Treponema pallidum | threonyl-tRNA synthetase | 0.0057 | 0.8494 | 1 |
Loa Loa (eye worm) | threonyl-tRNA synthetase | 0.0065 | 1 | 1 |
Trichomonas vaginalis | threonyl-tRNA synthetase, putative | 0.0057 | 0.8494 | 1 |
Echinococcus granulosus | Threonyl tRNA synthetase C | 0.0065 | 1 | 1 |
Wolbachia endosymbiont of Brugia malayi | threonyl-tRNA synthetase | 0.0057 | 0.8494 | 1 |
Mycobacterium ulcerans | threonyl-tRNA synthetase | 0.0057 | 0.8494 | 1 |
Entamoeba histolytica | threonyl-tRNA synthetase, putative | 0.0057 | 0.8494 | 1 |
Plasmodium falciparum | threonine--tRNA ligase | 0.0057 | 0.8494 | 1 |
Trypanosoma cruzi | threonyl-tRNA synthetase, putative | 0.0065 | 1 | 1 |
Toxoplasma gondii | threonyl-tRNA synthetase family protein | 0.0057 | 0.8494 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.