Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0063 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0044 | 0.0447 | 0.0203 |
Echinococcus multilocularis | cathepsin b | 0.0428 | 1 | 1 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0063 | 0.0918 | 0.0686 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Schistosoma mansoni | biogenic amine receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0063 | 0.0918 | 0.0918 |
Plasmodium vivax | vivapain-2 | 0.01 | 0.1839 | 1 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Schistosoma mansoni | opsin-like receptor | 0.0063 | 0.0918 | 0.0686 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.01 | 0.1839 | 0.1631 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0249 | 0.0249 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.01 | 0.1839 | 0.1631 |
Echinococcus granulosus | g protein coupled receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0036 | 0.0249 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0063 | 0.0918 | 0.0918 |
Echinococcus granulosus | allatostatin A receptor | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | GnHR receptor homolog | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0249 | 0.0249 |
Onchocerca volvulus | 0.01 | 0.1839 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0249 | 0.0249 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0249 | 0.0249 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | amine GPCR | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | opsin-like receptor | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | RE15519p | 0.0063 | 0.0918 | 0.0686 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0063 | 0.0918 | 0.0808 |
Onchocerca volvulus | 0.01 | 0.1839 | 1 | |
Loa Loa (eye worm) | calpain family protein 1 | 0.0042 | 0.0399 | 0.0399 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0044 | 0.0447 | 0.0203 |
Brugia malayi | cathepsin L-like precursor | 0.01 | 0.1839 | 0.1631 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0808 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Schistosoma mansoni | neuropeptide receptor | 0.0063 | 0.0918 | 0.0686 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0157 | 0.3265 | 0.3093 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus granulosus | cathepsin l1 | 0.01 | 0.1839 | 0.1631 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Schistosoma mansoni | amine GPCR | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | serotonin receptor | 0.0063 | 0.0918 | 0.0808 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Onchocerca volvulus | Cathepsin F homolog | 0.01 | 0.1839 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0428 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.01 | 0.1839 | 1 |
Echinococcus multilocularis | g protein coupled receptor | 0.0063 | 0.0918 | 0.0808 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | cysteine protease | 0.01 | 0.1839 | 0.174 |
Onchocerca volvulus | Cathepsin L homolog | 0.0036 | 0.0249 | 0.1352 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Echinococcus multilocularis | g protein coupled receptor | 0.0063 | 0.0918 | 0.0808 |
Brugia malayi | putative neuropeptide receptor | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | Papain family cysteine protease containing protein | 0.01 | 0.1839 | 0.1631 |
Toxoplasma gondii | cathepsin B | 0.0157 | 0.3265 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.01 | 0.1839 | 0.1631 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0063 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0808 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.01 | 0.1839 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.01 | 0.1839 | 0.174 |
Schistosoma mansoni | neuropeptide receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | neuropeptide receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | g protein coupled receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | neuropeptide receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | cathepsin b | 0.0428 | 1 | 1 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0063 | 0.0918 | 0.0918 |
Giardia lamblia | Cathepsin B precursor | 0.0157 | 0.3265 | 1 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0063 | 0.0918 | 0.0918 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.01 | 0.1839 | 1 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0063 | 0.0918 | 0.0808 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0063 | 0.0918 | 0.0808 |
Entamoeba histolytica | cysteine proteinase, putative | 0.01 | 0.1839 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Schistosoma mansoni | neuropeptide receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | fmrfamide receptor | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0428 | 1 | 1 |
Echinococcus multilocularis | fmrfamide receptor | 0.0063 | 0.0918 | 0.0808 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | cysteine protease | 0.01 | 0.1839 | 0.174 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | Dopamine receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | sex peptide receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0063 | 0.0918 | 0.0808 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0428 | 1 | 1 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Echinococcus granulosus | g protein coupled receptor | 0.0063 | 0.0918 | 0.0686 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Giardia lamblia | Cathepsin B precursor | 0.0157 | 0.3265 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0063 | 0.0918 | 0.0686 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0063 | 0.0918 | 0.0808 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Brugia malayi | G-protein coupled receptor | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | G-protein coupled receptor | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | Serotonin receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | fibroinase | 0.01 | 0.1839 | 0.1839 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.01 | 0.1839 | 0.1631 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.01 | 0.1839 | 0.174 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.01 | 0.1839 | 0.1631 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | cathepsin b | 0.0428 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.01 | 0.1839 | 1 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0063 | 0.0918 | 0.0686 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | cysteine protease | 0.01 | 0.1839 | 0.1839 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.01 | 0.1839 | 0.1631 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Brugia malayi | AKH receptor | 0.0063 | 0.0918 | 0.0686 |
Plasmodium vivax | vivapain-2 | 0.01 | 0.1839 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.01 | 0.1839 | 0.174 |
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0063 | 0.0918 | 0.0686 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Echinococcus granulosus | neuropeptide s receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | somatostatin receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0063 | 0.0918 | 0.0686 |
Onchocerca volvulus | 0.01 | 0.1839 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0063 | 0.0918 | 0.0808 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | g protein coupled receptor | 0.0063 | 0.0918 | 0.0808 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0157 | 0.3265 | 1 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0063 | 0.0918 | 0.0686 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0063 | 0.0918 | 0.0808 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0063 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.01 | 0.1839 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | cathepsin b | 0.0428 | 1 | 1 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0063 | 0.0918 | 0.0686 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.01 | 0.1839 | 0.1631 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0063 | 0.0918 | 0.0808 |
Schistosoma mansoni | amine GPCR | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Brugia malayi | Dopamine receptor protein 2 | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | fmrfamide receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0063 | 0.0918 | 0.0808 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | sex peptide receptor | 0.0063 | 0.0918 | 0.0808 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0044 | 0.0447 | 0.0331 |
Brugia malayi | sulfakinin receptor protein | 0.0063 | 0.0918 | 0.0686 |
Entamoeba histolytica | cysteine proteinase, putative | 0.01 | 0.1839 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.01 | 0.1839 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.01 | 0.1839 | 0.1631 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0036 | 0.0249 | 0.0249 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0808 |
Brugia malayi | calpain family protein 1 | 0.0042 | 0.0399 | 0.0154 |
Brugia malayi | Cathepsin L-like precursor | 0.01 | 0.1839 | 0.1631 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | neuropeptide receptor | 0.0063 | 0.0918 | 0.0808 |
Brugia malayi | Cathepsin L-like precursor | 0.01 | 0.1839 | 0.1631 |
Schistosoma mansoni | amine GPCR | 0.0063 | 0.0918 | 0.0686 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Brugia malayi | Melatonin receptor type 1A | 0.0063 | 0.0918 | 0.0686 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Brugia malayi | neuropeptide F receptor | 0.0063 | 0.0918 | 0.0686 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Onchocerca volvulus | 0.01 | 0.1839 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0157 | 0.3265 | 0.3093 |
Echinococcus multilocularis | neuropeptide receptor | 0.0063 | 0.0918 | 0.0808 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0063 | 0.0918 | 0.0808 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Echinococcus multilocularis | calpain A | 0.0044 | 0.0447 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Toxoplasma gondii | cathepsin CPL | 0.01 | 0.1839 | 0.5274 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0063 | 0.0918 | 0.0686 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.01 | 0.1839 | 0.1631 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | Cathepsin L-like precursor | 0.01 | 0.1839 | 0.1631 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Onchocerca volvulus | Cathepsin L homolog | 0.01 | 0.1839 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0063 | 0.0918 | 0.0808 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0063 | 0.0918 | 0.0808 |
Brugia malayi | larval opioid receptor | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | Dopamine receptor protein 1 | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0063 | 0.0918 | 0.0808 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0808 |
Entamoeba histolytica | cysteine proteinase, putative | 0.01 | 0.1839 | 1 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0428 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.01 | 0.1839 | 0.1631 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0249 | 0.0249 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1839 | 0.1839 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1839 | 0.1839 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Brugia malayi | Cathepsin L-like precursor | 0.01 | 0.1839 | 0.1631 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus granulosus | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0063 | 0.0918 | 0.0686 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0063 | 0.0918 | 0.0918 |
Brugia malayi | Cathepsin L-like precursor | 0.01 | 0.1839 | 0.1631 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | biogenic amine receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Brugia malayi | G protein-coupled receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | Cathepsin L-like precursor | 0.01 | 0.1839 | 0.1631 |
Echinococcus granulosus | calpain A | 0.0044 | 0.0447 | 0.0203 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0042 | 0.0399 | 0.0154 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0428 | 1 | 1 |
Schistosoma mansoni | myosin xvIII | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0063 | 0.0918 | 0.0808 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | serotonin receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0036 | 0.0249 | 0.0249 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | neuropeptide F receptor | 0.0063 | 0.0918 | 0.0686 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.01 | 0.1839 | 0.1631 |
Echinococcus granulosus | orexin receptor type 2 | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Brugia malayi | hypothetical protein | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0063 | 0.0918 | 0.0686 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.01 | 0.1839 | 0.1631 |
Schistosoma mansoni | biogenic amine receptor | 0.0063 | 0.0918 | 0.0686 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0063 | 0.0918 | 0.0686 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.01 | 0.1839 | 0.1631 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0063 | 0.0918 | 0.499 |
Echinococcus multilocularis | serotonin receptor | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0063 | 0.0918 | 0.0808 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.01 | 0.1839 | 0.1631 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0063 | 0.0918 | 0.499 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0279 | 0.0279 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0063 | 0.0918 | 0.0808 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Brugia malayi | follicle stimulating hormone receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.01 | 0.1839 | 0.1839 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0063 | 0.0918 | 0.0808 |
Schistosoma mansoni | opsin-like receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0063 | 0.0918 | 0.0808 |
Onchocerca volvulus | 0.01 | 0.1839 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Brugia malayi | Serotonin receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | allatostatin A receptor | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | cathepsin B | 0.0157 | 0.3265 | 0.3265 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0157 | 0.3265 | 1 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0399 | 0.0399 |
Schistosoma mansoni | histamine h1 receptor | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | amine GPCR | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | cathepsin L | 0.0036 | 0.0249 | 0.013 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Giardia lamblia | Cathepsin B precursor | 0.0157 | 0.3265 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0044 | 0.0447 | 0.0203 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1839 | 0.1839 |
Echinococcus multilocularis | somatostatin receptor | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0249 | 0.0249 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0063 | 0.0918 | 0.0808 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0063 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.01 | 0.1839 | 1 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0063 | 0.0918 | 0.0808 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | cathepsin L | 0.0036 | 0.0249 | 0.013 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.01 | 0.1839 | 0.1631 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0157 | 0.3265 | 1 |
Echinococcus granulosus | neuropeptide receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1839 | 0.1839 |
Brugia malayi | calpain family protein 1 | 0.0042 | 0.0399 | 0.0154 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0808 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0063 | 0.0918 | 0.0686 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.01 | 0.1839 | 0.1839 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0428 | 1 | 1 |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0063 | 0.0918 | 0.0686 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0063 | 0.0918 | 0.0808 |
Onchocerca volvulus | 0.01 | 0.1839 | 1 | |
Loa Loa (eye worm) | calpain family protein 1 | 0.0031 | 0.012 | 0.012 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.01 | 0.1839 | 0.174 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0063 | 0.0918 | 0.0918 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Onchocerca volvulus | 0.0063 | 0.0918 | 0.499 | |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0063 | 0.0918 | 0.0686 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0918 | 0.0918 |
Brugia malayi | ORL1-like opioid receptor | 0.0063 | 0.0918 | 0.0686 |
Onchocerca volvulus | 0.0036 | 0.0249 | 0.1352 | |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0063 | 0.0918 | 0.0686 |
Echinococcus granulosus | g-protein coupled receptor | 0.0063 | 0.0918 | 0.0686 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.01 | 0.1839 | 0.5274 |
Loa Loa (eye worm) | ctsf protein | 0.01 | 0.1839 | 0.1839 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.01 | 0.1839 | 0.5274 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 56.3 % | Antiparkinsonian activity against haloperidol-induced catalepsy in Mus musculus Swiss albino (mouse) assessed reduction in catalepsy at 100 mg/kg, ip administered 30 min prior to haloperidol injection measured after 30 to 180 min | ChEMBL. | No reference |
TIME (functional) | = 77 s | Antiparkinsonian activity against haloperidol-induced catalepsy in Mus musculus Swiss albino (mouse) assessed as decrease in mean descent time at 100 mg/kg, ip administered 30 min prior to haloperidol injection measured after 30 min | ChEMBL. | No reference |
TIME (functional) | = 89 s | Antiparkinsonian activity against haloperidol-induced catalepsy in Mus musculus Swiss albino (mouse) assessed as decrease in mean descent time at 100 mg/kg, ip administered 30 min prior to haloperidol injection measured after 60 min | ChEMBL. | No reference |
TIME (functional) | = 114 s | Antiparkinsonian activity against haloperidol-induced catalepsy in Mus musculus Swiss albino (mouse) assessed as decrease in mean descent time at 100 mg/kg, ip administered 30 min prior to haloperidol injection measured after 90 min | ChEMBL. | No reference |
TIME (functional) | = 118 s | Antiparkinsonian activity against haloperidol-induced catalepsy in Mus musculus Swiss albino (mouse) assessed as decrease in mean descent time at 100 mg/kg, ip administered 30 min prior to haloperidol injection measured after 120 min | ChEMBL. | No reference |
TIME (functional) | = 129 s | Antiparkinsonian activity against haloperidol-induced catalepsy in Mus musculus Swiss albino (mouse) assessed as decrease in mean descent time at 100 mg/kg, ip administered 30 min prior to haloperidol injection measured after 150 min | ChEMBL. | No reference |
TIME (functional) | = 173 s | Antiparkinsonian activity against haloperidol-induced catalepsy in Mus musculus Swiss albino (mouse) assessed as decrease in mean descent time at 100 mg/kg, ip administered 30 min prior to haloperidol injection measured after 180 min | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.