Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | cell division protein CDC48CY | 0.1012 | 1 | 1 |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0792 | 0.7161 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0475 | 0.3051 | 0.2945 |
Schistosoma mansoni | tyrosine kinase | 0.0475 | 0.3051 | 0.2945 |
Entamoeba histolytica | cdc48-like protein, putative | 0.096 | 0.9326 | 0.5 |
Plasmodium vivax | cell division cycle protein 48 homologue, putative | 0.096 | 0.9326 | 1 |
Entamoeba histolytica | transitional endoplasmic reticulum ATPase, putative | 0.096 | 0.9326 | 0.5 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0792 | 0.7161 | 1 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.1012 | 1 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0792 | 0.7161 | 0.7118 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0475 | 0.3051 | 0.2945 |
Trypanosoma cruzi | Valosin-containing protein, putative | 0.096 | 0.9326 | 0.5 |
Plasmodium falciparum | cell division cycle protein 48 homologue, putative | 0.096 | 0.9326 | 0.5 |
Loa Loa (eye worm) | VCP protein | 0.0418 | 0.232 | 0.3095 |
Giardia lamblia | AAA family ATPase | 0.0606 | 0.4742 | 0.5 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0475 | 0.3051 | 0.2945 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.0418 | 0.232 | 0.2203 |
Trypanosoma brucei | Valosin-containing protein | 0.096 | 0.9326 | 0.5 |
Toxoplasma gondii | cell division protein CDC48AP | 0.0606 | 0.4742 | 0.0000097958 |
Schistosoma mansoni | tyrosine kinase | 0.0471 | 0.3001 | 0.2894 |
Schistosoma mansoni | tyrosine kinase | 0.0471 | 0.3001 | 0.2894 |
Leishmania major | Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog | 0.096 | 0.9326 | 0.5 |
Brugia malayi | transitional endoplasmic reticulum ATPase TER94, putative | 0.0418 | 0.232 | 0.3095 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0418 | 0.232 | 0.2203 |
Loa Loa (eye worm) | vesicle-fusing ATPase | 0.0593 | 0.4584 | 0.6325 |
Mycobacterium tuberculosis | Putative conserved ATPase | 0.0606 | 0.4742 | 0.5 |
Brugia malayi | valosin containing protein | 0.0593 | 0.4584 | 0.6325 |
Schistosoma mansoni | tyrosine kinase | 0.0471 | 0.3001 | 0.2894 |
Loa Loa (eye worm) | hypothetical protein | 0.0593 | 0.4584 | 0.6325 |
Brugia malayi | vesicle-fusing ATPase | 0.0593 | 0.4584 | 0.6325 |
Schistosoma mansoni | tyrosine kinase | 0.0475 | 0.3051 | 0.2945 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.096 | 0.9326 | 0.9316 |
Schistosoma mansoni | tyrosine kinase | 0.0792 | 0.7161 | 0.7118 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0792 | 0.7161 | 0.7118 |
Echinococcus multilocularis | 0.0319 | 0.1028 | 0.0891 | |
Mycobacterium ulcerans | ATPase | 0.0606 | 0.4742 | 0.5 |
Onchocerca volvulus | Transitional endoplasmic reticulum ATPase homolog | 0.1012 | 1 | 0.5 |
Trichomonas vaginalis | spermatogenesis associated factor, putative | 0.1012 | 1 | 1 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.1012 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.