Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | cell division protein CDC48AP | 0.0362 | 0.5363 | 0.0000097958 |
Trichomonas vaginalis | spermatogenesis associated factor, putative | 0.0606 | 1 | 1 |
Plasmodium falciparum | cell division cycle protein 48 homologue, putative | 0.0574 | 0.9406 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0355 | 0.5224 | 1 |
Entamoeba histolytica | transitional endoplasmic reticulum ATPase, putative | 0.0574 | 0.9406 | 1 |
Mycobacterium tuberculosis | Putative conserved ATPase | 0.0362 | 0.5363 | 0.5 |
Leishmania major | Transitional endoplasmic reticulum ATPase, putative,valosin-containing protein homolog | 0.0574 | 0.9406 | 0.5 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.025 | 0.3228 | 0.3228 |
Mycobacterium ulcerans | ATPase | 0.0362 | 0.5363 | 0.5 |
Plasmodium vivax | cell division cycle protein 48 homologue, putative | 0.0574 | 0.9406 | 1 |
Trypanosoma cruzi | Valosin-containing protein, putative | 0.0574 | 0.9406 | 0.5 |
Toxoplasma gondii | cell division protein CDC48CY | 0.0606 | 1 | 1 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0574 | 0.9406 | 0.9406 |
Giardia lamblia | AAA family ATPase | 0.0362 | 0.5363 | 0.5 |
Brugia malayi | vesicle-fusing ATPase | 0.0355 | 0.5224 | 1 |
Echinococcus multilocularis | transitional endoplasmic reticulum atpase | 0.0606 | 1 | 1 |
Trypanosoma brucei | Valosin-containing protein | 0.0574 | 0.9406 | 0.5 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.025 | 0.3228 | 0.3228 |
Schistosoma mansoni | cell division control protein 48 aaa family protein | 0.0606 | 1 | 1 |
Brugia malayi | valosin containing protein | 0.0355 | 0.5224 | 1 |
Brugia malayi | transitional endoplasmic reticulum ATPase TER94, putative | 0.025 | 0.3228 | 0.6178 |
Onchocerca volvulus | Transitional endoplasmic reticulum ATPase homolog | 0.0606 | 1 | 0.5 |
Entamoeba histolytica | cdc48-like protein, putative | 0.0574 | 0.9406 | 1 |
Loa Loa (eye worm) | vesicle-fusing ATPase | 0.0355 | 0.5224 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.