Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.006 | 0.0344 | 0.0379 |
Leishmania major | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.1962 | 0.2164 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0349 | 0.2138 | 0.2358 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0074 | 0.0434 | 0.172 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0005 | 0.0002 | 0.0002 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0056 | 0.0318 | 0.1257 |
Brugia malayi | conserved hypotetical protein | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0042 | 0.023 | 0.0254 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | muscleblind protein | 0.032 | 0.1962 | 0.2164 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.0151 | 0.0166 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | DNA-binding protein D-ETS-3 | 0.0011 | 0.0041 | 0.0045 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0045 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Possible polyprenyl synthetase IdsB (polyprenyl transferase) (polyprenyl diphosphate synthase) | 0.0411 | 0.2525 | 0.2784 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1188 | 0.1309 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.031 | 0.0342 |
Loa Loa (eye worm) | geranylgeranyl pyrophosphate synthetase | 0.0582 | 0.3585 | 0.3952 |
Mycobacterium leprae | Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0428 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0074 | 0.0434 | 0.0479 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0005 | 0.0004 | 0.0004 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0298 | 0.0328 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | Polyprenyl synthetase family protein | 0.1465 | 0.907 | 1 |
Loa Loa (eye worm) | RecQ helicase | 0.0024 | 0.0122 | 0.0134 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Schistosoma mansoni | hypothetical protein | 0.0196 | 0.1188 | 0.1309 |
Brugia malayi | AMP-binding enzyme family protein | 0.0074 | 0.0434 | 0.0479 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0061 | 0.0351 | 0.0387 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0019 | 0.0089 | 0.0098 |
Trichomonas vaginalis | geranylgeranyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0005 | 0.0002 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Echinococcus granulosus | ewsr:fli fusion protein type | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0076 | 0.0444 | 0.049 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | acetyl coenzyme A synthetase cytoplasmic | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0017 | 0.0018 |
Mycobacterium tuberculosis | P-hydroxybenzoyl-AMP ligase FadD22 | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | ets | 0.0011 | 0.0041 | 0.0045 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0042 | 0.023 | 0.023 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0016 | 0.0073 | 0.0078 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0056 | 0.0318 | 0.035 |
Loa Loa (eye worm) | hypothetical protein | 0.032 | 0.1962 | 0.2164 |
Plasmodium vivax | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.0376 | 0.0414 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0298 | 0.0328 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.0002 | 0.0002 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0035 | 0.0035 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0028 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium tuberculosis | Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0028 | 0.003 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.0035 | 0.0038 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0035 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtF | 0.0022 | 0.0108 | 0.0119 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0277 | 0.0305 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0165 | 0.0997 | 0.11 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Probable polyprenyl-diphosphate synthase GrcC2 (polyprenyl pyrophosphate synthetase) | 0.0411 | 0.2525 | 0.2784 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0074 | 0.0434 | 0.0479 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Treponema pallidum | octaprenyl-diphosphate synthase | 0.0582 | 0.3585 | 1 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.0582 | 0.3585 | 0.3952 |
Loa Loa (eye worm) | DR-78 | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | Ets-domain containing protein | 0.0011 | 0.0041 | 0.0045 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | geranylgeranyl pyrophosphate synthase | 0.0582 | 0.3585 | 0.3952 |
Echinococcus multilocularis | GA binding protein alpha chain | 0.0076 | 0.0444 | 0.0444 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | geranylgeranyl pyrophosphate synthase | 0.0582 | 0.3585 | 0.3585 |
Echinococcus multilocularis | ets variant gene 4 | 0.0011 | 0.0041 | 0.0041 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0074 | 0.0434 | 0.0479 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | gabp alpha | 0.0076 | 0.0444 | 0.049 |
Mycobacterium tuberculosis | Probable peptide synthetase Nrp (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | acetyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase | 0.0022 | 0.0108 | 0.0119 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0005 | 0.0002 | 0.0042 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.0035 | 0.0035 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0049 | 0.0277 | 0.0305 |
Schistosoma mansoni | elf1 | 0.0011 | 0.0041 | 0.0045 |
Echinococcus granulosus | ETS transcription factor Elf 5 | 0.0011 | 0.0041 | 0.0045 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.0035 | 0.0799 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0022 | 0.0108 | 0.0119 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0259 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Trypanosoma brucei | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.0035 | 0.0799 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0005 | 0.0004 | 0.0004 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0024 | 0.0122 | 0.0134 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0298 | 0.0298 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0056 | 0.0318 | 0.035 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0259 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Plasmodium falciparum | octaprenyl pyrophosphate synthase | 0.0411 | 0.2525 | 0.2757 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0161 | 0.0161 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Onchocerca volvulus | 0.0074 | 0.0434 | 1 | |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.001 | 0.0034 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | geminin | 0.0196 | 0.1188 | 0.1309 |
Schistosoma mansoni | trans-prenyltransferase | 0.0411 | 0.2525 | 0.2784 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0041 |
Echinococcus granulosus | geranylgeranyl pyrophosphate synthase | 0.0582 | 0.3585 | 0.3952 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0027 | 0.003 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0161 | 0.0177 |
Trypanosoma brucei | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0035 | 0.0035 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | AMP-binding enzyme family protein | 0.0074 | 0.0434 | 0.0479 |
Echinococcus granulosus | ETS transcription factor Elf 1 | 0.0011 | 0.0041 | 0.0045 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0411 | 0.2525 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Trypanosoma brucei | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.001 | 0.0034 | 0.0037 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | O-succinylbenzoic acid--CoA ligase | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | D-ets-4 DNA binding domain-containing protein | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0108 | 0.0119 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0074 | 0.0434 | 0.0479 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthase, putative | 0.0411 | 0.2525 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | hypothetical protein | 0.0121 | 0.0723 | 0.0797 |
Schistosoma mansoni | glutathione synthetase | 0.0411 | 0.2525 | 0.2784 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.001 | 0.0034 | 0.0034 |
Echinococcus multilocularis | protein C ets 2 | 0.0011 | 0.0041 | 0.0041 |
Echinococcus multilocularis | muscleblind protein | 0.032 | 0.1962 | 0.1962 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | peptide synthetase Nrp (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0017 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 0.907 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0035 | 0.0038 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0024 | 0.0122 | 0.0134 |
Onchocerca volvulus | 0.001 | 0.0035 | 0.0799 | |
Echinococcus granulosus | bloom syndrome protein | 0.0024 | 0.0122 | 0.0134 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0931 |
Brugia malayi | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.0035 | 0.0799 |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.0411 | 0.2525 | 0.2784 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.0002 | 0.0002 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Trypanosoma cruzi | solanesyl-diphosphate synthase | 0.0411 | 0.2525 | 0.2784 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0052 | 0.0057 |
Leishmania major | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | ets-related | 0.0011 | 0.0041 | 0.0045 |
Mycobacterium tuberculosis | Peptide synthetase MbtF (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | tailless protein | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Loa Loa (eye worm) | ets-domain-containing protein | 0.0011 | 0.0041 | 0.0045 |
Toxoplasma gondii | propionate-CoA ligase | 0.0022 | 0.0108 | 0.0119 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0074 | 0.0434 | 0.0479 |
Leishmania major | polyprenyl synthase, putative | 0.0582 | 0.3585 | 0.3952 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0052 | 0.0298 | 0.0328 |
Echinococcus granulosus | protein C ets 2 | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.0035 | 0.0038 |
Onchocerca volvulus | 0.0005 | 0.0002 | 0.0042 | |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0005 | 0.0006 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Brugia malayi | Inositol-1 | 0.0042 | 0.0235 | 0.0259 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0161 | 0.0177 |
Brugia malayi | ecdysone receptor | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.0035 | 0.0035 |
Trypanosoma cruzi | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Plasmodium vivax | geranylgeranyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Brugia malayi | acetyl-Coenzyme A synthetase 2 | 0.0022 | 0.0108 | 0.0119 |
Toxoplasma gondii | AMP-binding enzyme domain-containing protein | 0.0022 | 0.0108 | 0.0119 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.0035 | 0.0038 |
Onchocerca volvulus | 0.0029 | 0.0151 | 0.3472 | |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | ewsr:fli fusion protein type | 0.0011 | 0.0041 | 0.0041 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.001 | 0.0034 | 0.0034 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0013 | 0.0052 | 0.0057 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0016 | 0.0072 | 0.0079 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Schistosoma mansoni | DNA helicase recq5 | 0.001 | 0.0034 | 0.0037 |
Brugia malayi | hypothetical protein | 0.0042 | 0.023 | 0.0254 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0074 | 0.0434 | 0.0479 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma cruzi | farnesyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Brugia malayi | AMP-binding enzyme family protein | 0.0074 | 0.0434 | 0.0479 |
Echinococcus granulosus | prenyl decaprenyl diphosphate synthase | 0.0411 | 0.2525 | 0.2784 |
Echinococcus granulosus | decaprenyl diphosphate synthase subunit 1 | 0.0411 | 0.2525 | 0.2784 |
Trypanosoma cruzi | long-chain-fatty-acid-CoA ligase, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.0035 | 0.0035 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0005 | 0.0005 | 0.0006 |
Trichomonas vaginalis | antibiotic synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | geranylgeranyl pyrophosphate synthetase | 0.0582 | 0.3585 | 0.3952 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0042 | 0.023 | 0.0254 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0028 | 0.003 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0049 | 0.0277 | 0.0305 |
Echinococcus granulosus | ETS domain containing protein Elk 1 | 0.0011 | 0.0041 | 0.0045 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0349 | 0.2138 | 0.2358 |
Plasmodium falciparum | geranylgeranyl pyrophosphate synthase, putative | 0.1465 | 0.907 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | ETS domain containing protein Elk 1 | 0.0011 | 0.0041 | 0.0041 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0034 | 0.0037 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0298 | 0.0328 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0049 | 0.0277 | 0.0305 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0042 | 0.0235 | 0.0235 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0052 | 0.0057 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0349 | 0.2138 | 0.2358 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.001 | 0.0034 | 0.0037 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Mycobacterium leprae | POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0022 | 0.0108 | 0.0428 |
Toxoplasma gondii | hypothetical protein | 0.0056 | 0.0322 | 0.0355 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0005 | 0.0002 | 0.0002 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.0019 | 0.009 | 0.0099 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0074 | 0.0434 | 0.172 |
Entamoeba histolytica | bifunctional short chain isoprenyl diphosphate synthase, putative | 0.0411 | 0.2525 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0005 | 0.0005 | 0.0006 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0052 | 0.0298 | 0.0298 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0056 | 0.0318 | 0.0347 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.0411 | 0.2525 | 0.2784 |
Onchocerca volvulus | 0.0005 | 0.0002 | 0.0042 | |
Mycobacterium tuberculosis | Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium ulcerans | phenyloxazoline synthase MbtB | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0013 | 0.0052 | 0.0057 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.0444 | 0.049 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0035 | 0.0038 |
Chlamydia trachomatis | geranylgeranyl pyrophosphate synthase | 0.0411 | 0.2525 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0056 | 0.0318 | 0.0314 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.0035 | 0.0035 |
Mycobacterium ulcerans | polyprenyl synthetase IdsB | 0.0411 | 0.2525 | 0.2784 |
Mycobacterium tuberculosis | Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) | 0.0022 | 0.0108 | 0.0119 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0024 | 0.0122 | 0.0134 |
Leishmania major | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0041 | 0.0045 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0017 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | transcription factor E74 isoform | 0.0011 | 0.0041 | 0.0045 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Schistosoma mansoni | polyomavirus enhancer activator 3 pea3 | 0.0011 | 0.0041 | 0.0045 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.001 | 0.0034 | 0.0037 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0052 | 0.0298 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0002 | 0.0002 |
Echinococcus multilocularis | decaprenyl diphosphate synthase subunit 1 | 0.0411 | 0.2525 | 0.2525 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.0151 | 0.0166 |
Mycobacterium ulcerans | geranylgeranyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.0235 | 0.0259 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0005 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Mycobacterium ulcerans | bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase | 0.0022 | 0.0108 | 0.0119 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Echinococcus multilocularis | prenyl (decaprenyl) diphosphate synthase | 0.0411 | 0.2525 | 0.2525 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.0035 | 0.0038 |
Entamoeba histolytica | recQ family DNA helicase | 0.0005 | 0.0004 | 0.0015 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Brugia malayi | nuclear receptor NHR-67 | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Entamoeba histolytica | geranylgeranyl pyrophosphate synthetase, putative | 0.0411 | 0.2525 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Schistosoma mansoni | hypothetical protein | 0.0042 | 0.023 | 0.0254 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0035 | 0.0038 |
Leishmania major | mitochondrial DNA polymerase beta | 0.0349 | 0.2138 | 0.2358 |
Mycobacterium ulcerans | long-chain-acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Probable geranylgeranyl pyrophosphate synthetase IdsA2 (ggppsase) (GGPP synthetase) (geranylgeranyl diphosphate synthase) | 0.1465 | 0.907 | 1 |
Trypanosoma cruzi | polyprenyl synthase, putative | 0.0582 | 0.3585 | 0.3952 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Echinococcus granulosus | GA binding protein alpha chain | 0.0076 | 0.0444 | 0.049 |
Brugia malayi | Ets-domain containing protein | 0.0076 | 0.0444 | 0.049 |
Echinococcus multilocularis | muscleblind protein 1 | 0.032 | 0.1962 | 0.1962 |
Loa Loa (eye worm) | inositol-1 | 0.0042 | 0.0235 | 0.0259 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0053 | 0.0299 | 0.0329 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0074 | 0.0434 | 0.172 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0005 | 0.0005 | 0.0005 |
Entamoeba histolytica | recQ family helicase, putative | 0.0005 | 0.0003 | 0.001 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0074 | 0.0434 | 0.172 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium tuberculosis | Probable multifunctional geranylgeranyl pyrophosphate synthetase IdsA1 (GGPP synthetase) (ggppsase) (geranylgeranyl diphosphate | 0.0411 | 0.2525 | 0.2784 |
Giardia lamblia | Farnesyl diphosphate synthase | 0.1465 | 0.907 | 1 |
Echinococcus granulosus | farnesyl pyrophosphate synthase | 0.1465 | 0.907 | 1 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0038 | 0.0208 | 0.0822 |
Schistosoma mansoni | inositol monophosphatase | 0.0042 | 0.0235 | 0.0259 |
Trypanosoma brucei | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Echinococcus multilocularis | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0041 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0074 | 0.0434 | 0.0479 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0042 | 0.0235 | 0.0259 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0021 | 0.0103 | 0.0077 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0035 | 0.0038 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0042 | 0.0235 | 0.0259 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0165 | 0.0997 | 0.11 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.0035 | 0.0038 |
Mycobacterium leprae | POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) | 0.0022 | 0.0108 | 0.0428 |
Wolbachia endosymbiont of Brugia malayi | geranylgeranyl pyrophosphate synthase | 0.0411 | 0.2525 | 1 |
Trypanosoma cruzi | solanesyl-diphosphate synthase, putative | 0.0411 | 0.2525 | 0.2784 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.0151 | 0.0166 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0042 | 0.0235 | 0.0259 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0052 | 0.0298 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0318 | 0.035 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.0035 | 0.0038 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0038 | 0.0208 | 0.0229 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0184 | 0.1113 | 0.1227 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.0035 | 0.0038 |
Mycobacterium ulcerans | hypothetical protein | 0.0074 | 0.0434 | 0.0479 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Toxoplasma gondii | polyprenyl synthetase superfamily protein | 0.1465 | 0.907 | 1 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.001 | 0.0034 | 0.0037 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0017 | 0.0017 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.0035 | 0.0038 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0052 | 0.0298 | 0.0328 |
Plasmodium vivax | octaprenyl pyrophosphate synthase, putative | 0.0411 | 0.2525 | 0.2782 |
Entamoeba histolytica | long-chain-fatty-acid--CoA ligase, putative | 0.0022 | 0.0108 | 0.0428 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.0035 | 0.0038 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0005 | 0.0002 | 0.0002 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0005 | 0.0006 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0005 | 0.0004 | 0.0004 |
Mycobacterium tuberculosis | Peptide synthetase MbtE (peptide synthase) | 0.0022 | 0.0108 | 0.0119 |
Loa Loa (eye worm) | fli-1 protein | 0.0231 | 0.1405 | 0.1549 |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | oxidoreductase | 0.0022 | 0.0108 | 0.0119 |
Entamoeba histolytica | recQ family helicase, putative | 0.0013 | 0.0052 | 0.0206 |
Mycobacterium ulcerans | polyprenyl diphosphate synthetase, GrcC1 | 0.0411 | 0.2525 | 0.2784 |
Mycobacterium ulcerans | hypothetical protein | 0.0184 | 0.1113 | 0.1227 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | D-ets-2 protein | 0.0011 | 0.0041 | 0.0045 |
Schistosoma mansoni | DNA helicase recq1 | 0.001 | 0.0034 | 0.0037 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0074 | 0.0434 | 0.172 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0005 | 0.0005 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0005 | 0.0005 | 0.0006 |
Brugia malayi | Polyprenyl synthetase family protein | 0.0411 | 0.2525 | 0.2784 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0165 | 0.0997 | 0.11 |
Echinococcus multilocularis | bloom syndrome protein | 0.0024 | 0.0122 | 0.0122 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0017 | 0.0017 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0013 | 0.0014 |
Brugia malayi | Muscleblind-like protein | 0.032 | 0.1962 | 0.2164 |
Echinococcus multilocularis | ETS transcription factor Elf 1 | 0.0011 | 0.0041 | 0.0041 |
Echinococcus multilocularis | acetyl coenzyme A synthetase, cytoplasmic | 0.0022 | 0.0108 | 0.0108 |
Toxoplasma gondii | Acetyl-coenzyme A synthetase 2, putative | 0.0022 | 0.0108 | 0.0119 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.0035 | 0.0038 |
Loa Loa (eye worm) | polyprenyl synthetase | 0.1465 | 0.907 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | geminin | 0.0196 | 0.1188 | 0.1188 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0074 | 0.0434 | 0.0479 |
Mycobacterium ulcerans | acetyl-CoA synthetase | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0042 | 0.0235 | 0.0259 |
Brugia malayi | Fli-1 protein | 0.0231 | 0.1405 | 0.1549 |
Trichomonas vaginalis | geranylgeranyl diphosphate synthase, putative | 0.1465 | 0.907 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.0035 | 0.0038 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.0035 | 0.0035 |
Brugia malayi | DNA-binding protein D-ETS-3 | 0.0011 | 0.0041 | 0.0045 |
Plasmodium falciparum | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0082 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0005 | 0.0006 |
Echinococcus multilocularis | ETS transcription factor Elf 5 | 0.0011 | 0.0041 | 0.0041 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0013 | 0.0014 |
Mycobacterium ulcerans | non-ribosomal peptide synthetase MbtE | 0.0022 | 0.0108 | 0.0119 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0005 | 0.0002 | 0.0002 |
Schistosoma mansoni | ets-related | 0.0231 | 0.1405 | 0.1549 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.0035 | 0.0038 |
Onchocerca volvulus | 0.0022 | 0.0108 | 0.2488 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0022 | 0.0108 | 0.0119 |
Leishmania major | acetyl-CoA synthetase, putative | 0.0022 | 0.0108 | 0.0119 |
Mycobacterium leprae | PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) | 0.0411 | 0.2525 | 1 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0013 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0002 | 0.0002 |
Entamoeba histolytica | hypothetical protein | 0.0042 | 0.023 | 0.0913 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0042 | 0.0235 | 0.0259 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0161 | 0.0177 |
Brugia malayi | nuclear receptor NHR-88 | 0.0005 | 0.0002 | 0.0002 |
Echinococcus granulosus | ETS transcription factor Elf 2 | 0.0011 | 0.0041 | 0.0045 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0005 | 0.0006 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ID50 (functional) | ~ 0.001 M | In vitro inhibition of growth of L1210 mouse leukemic cells | ChEMBL. | 7328577 |
ILS (functional) | = 1 % | Increase in life span of tumor L1210 leukemic mice 1-5 days after 200 mg/kg of the compound administered | ChEMBL. | 7328577 |
Toxicity (functional) | 0 | In vitro cytotoxicity of the compound against L1210 leukemic cells 1-5 days after administration of 200 mg/kg of the compound; Yes | ChEMBL. | 7328577 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.