Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | ceramide glucosyltransferase | 0.0471 | 0.4671 | 0.2582 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0765 | 1 | 1 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0471 | 0.4671 | 0.7627 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0765 | 1 | 1 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0213 | 0 | 0.5 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0502 | 0.5229 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0765 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0529 | 0.5719 | 0.1027 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0765 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0765 | 1 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0471 | 0.4671 | 0.4203 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0643 | 0.7799 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0643 | 0.7799 | 1 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0471 | 0.4671 | 0.3972 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0643 | 0.7799 | 0.751 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0471 | 0.4671 | 0.2582 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0643 | 0.7799 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0765 | 1 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0471 | 0.4671 | 0.4203 |
Schistosoma mansoni | alpha-glucosidase | 0.0554 | 0.6173 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0765 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0529 | 0.5719 | 0.1027 |
Schistosoma mansoni | alpha-glucosidase | 0.0554 | 0.6173 | 1 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0643 | 0.7799 | 0.5869 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.