Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glutamate receptor 2 | 0.0331 | 0.0349 | 0.0349 |
Echinococcus granulosus | bifunctional protein NCOAT | 0.5823 | 1 | 1 |
Echinococcus multilocularis | glutamate receptor subunit protein glur | 0.0271 | 0.0245 | 0.0245 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0354 | 0.0391 | 0.0391 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0157 | 0.0044 | 0.0044 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0157 | 0.0044 | 0.0044 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0379 | 0.0435 | 0.0435 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0379 | 0.0435 | 0.0435 |
Echinococcus granulosus | glutamate receptor 1 | 0.0222 | 0.0159 | 0.0159 |
Echinococcus granulosus | glutamate receptor 4 | 0.0222 | 0.0159 | 0.0159 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0379 | 0.0435 | 0.0435 |
Echinococcus granulosus | glutamate receptor 2 | 0.0331 | 0.0349 | 0.0349 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.0159 | 0.0159 |
Echinococcus multilocularis | bifunctional protein NCOAT | 0.5823 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2474 | 0.4115 | 0.4115 |
Loa Loa (eye worm) | hyaluronidase | 0.5823 | 1 | 1 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0157 | 0.0044 | 0.0044 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0157 | 0.0044 | 0.0044 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0354 | 0.0391 | 0.0391 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.0159 | 0.0159 |
Schistosoma mansoni | Hyaluronidase | 0.5823 | 1 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0157 | 0.0044 | 0.0044 |
Echinococcus granulosus | glutamate receptor 2 | 0.0379 | 0.0435 | 0.0435 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0157 | 0.0044 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0222 | 0.0159 | 0.0159 |
Echinococcus granulosus | glutamate receptor subunit protein glur | 0.0271 | 0.0245 | 0.0245 |
Schistosoma mansoni | aminopeptidase P homologue (M24 family) | 0.5823 | 1 | 1 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0157 | 0.0044 | 0.0044 |
Echinococcus multilocularis | glutamate receptor 4 | 0.0222 | 0.0159 | 0.0159 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.