Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1027 | 0.6677 | 0.6948 |
Schistosoma mansoni | alpha glucosidase | 0.0281 | 0.0925 | 0.0962 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0281 | 0.0925 | 0.5 |
Echinococcus granulosus | bile acid beta glucosidase | 0.1027 | 0.6677 | 0.6339 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0754 | 0.4575 | 0.4022 |
Schistosoma mansoni | alpha-glucosidase | 0.1302 | 0.8798 | 0.9155 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0522 | 0.2781 | 0.5084 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.1408 | 0.961 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0281 | 0.0925 | 0.5 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.1408 | 0.961 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0754 | 0.4575 | 0.4022 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.1027 | 0.6677 | 0.6339 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.1408 | 0.961 | 0.957 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Brugia malayi | Ceramide glucosyltransferase | 0.1408 | 0.961 | 0.957 |
Leishmania major | alpha glucosidase II subunit, putative | 0.0281 | 0.0925 | 0.5 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.1408 | 0.961 | 1 |
Onchocerca volvulus | 0.0875 | 0.5505 | 0.4164 | |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.1408 | 0.961 | 0.957 |
Trypanosoma brucei | glucosidase, putative | 0.0281 | 0.0925 | 0.5 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0281 | 0.0925 | 0.5 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0638 | 0.3678 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0693 | 0.4104 | 0.3503 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Schistosoma mansoni | alpha-glucosidase | 0.1302 | 0.8798 | 0.9155 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.1027 | 0.6677 | 0.6339 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0281 | 0.0925 | 0.5 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.1027 | 0.6677 | 0.6339 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.1408 | 0.961 | 0.957 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0281 | 0.0925 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0495 | 0.2575 | 0.4521 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0522 | 0.2781 | 0.5084 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0754 | 0.4575 | 1 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.1027 | 0.6677 | 0.6948 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.