Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Plasmodium vivax | vivapain-2 | 0.0027 | 0.086 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0027 | 0.086 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0274 | 0.1018 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0274 | 0.0274 |
Giardia lamblia | Cathepsin B precursor | 0.0051 | 0.2688 | 0.5 |
Onchocerca volvulus | Cathepsin F homolog | 0.0027 | 0.086 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Echinococcus multilocularis | cysteine protease | 0.0027 | 0.086 | 0.086 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0027 | 0.086 | 0.086 |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.0274 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0027 | 0.086 | 0.0603 |
Plasmodium vivax | vivapain-2 | 0.0027 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0051 | 0.2688 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.002 | 0.0274 | 0.0274 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Giardia lamblia | Cathepsin B precursor | 0.0051 | 0.2688 | 0.5 |
Loa Loa (eye worm) | fibroinase | 0.0027 | 0.086 | 0.0603 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0274 | 0.0274 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.086 | 0.0603 |
Loa Loa (eye worm) | cathepsin B | 0.0051 | 0.2688 | 0.2482 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0027 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.086 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0027 | 0.086 | 0.086 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.086 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0027 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Loa Loa (eye worm) | ctsf protein | 0.0027 | 0.086 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Brugia malayi | cathepsin L-like precursor | 0.002 | 0.0274 | 0.0274 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0027 | 0.086 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.002 | 0.0274 | 0.0274 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0027 | 0.086 | 0.086 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0027 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0051 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin l1 | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0274 | 0.1018 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Toxoplasma gondii | cathepsin B | 0.0051 | 0.2688 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0051 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Loa Loa (eye worm) | cysteine protease | 0.0027 | 0.086 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.086 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.0274 | 0.0274 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0051 | 0.2688 | 0.2688 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | Cathepsin L homolog | 0.0027 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Echinococcus multilocularis | cysteine protease | 0.0027 | 0.086 | 0.086 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0027 | 0.086 | 0.0603 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0027 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Giardia lamblia | Cathepsin B precursor | 0.0051 | 0.2688 | 0.5 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0051 | 0.2688 | 0.2688 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.086 | 0.3201 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.086 | 0.086 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | Cathepsin L homolog | 0.0027 | 0.086 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.002 | 0.0274 | 0.0274 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0027 | 0.086 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.086 | 0.3201 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0027 | 0.086 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0027 | 0.086 | 0.086 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.