Detailed information for compound 1842856

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 504.526 | Formula: C26H32O10
  • H donors: 0 H acceptors: 4 LogP: 1.73 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 2
  • SMILES: CC(=O)OC[C@@]12[C@@H](OC(=O)C)C[C@H]([C@@]3([C@H]1CC[C@@H]([C@@]12CO1)OC(=O)C)C[C@@H](OC3=O)c1cocc1)C
  • InChi: 1S/C26H32O10/c1-14-9-22(35-17(4)29)25(12-32-15(2)27)20(5-6-21(34-16(3)28)26(25)13-33-26)24(14)10-19(36-23(24)30)18-7-8-31-11-18/h7-8,11,14,19-22H,5-6,9-10,12-13H2,1-4H3/t14-,19-,20-,21+,22+,24-,25+,26-/m1/s1
  • InChiKey: RCVVNRBNRKRZGL-BMQMGEQGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0347 0.3424 0.3424
Leishmania major hypothetical protein, conserved 0.0347 0.3424 0.5
Echinococcus granulosus SWI:SNF matrix associated 0.0976 1 1
Loa Loa (eye worm) brahma associated protein 0.0976 1 1
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0976 1 1
Giardia lamblia Kinase 0.002 0 0.5
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0347 0.3424 0.1186
Schistosoma mansoni zinc finger protein 0.0347 0.3424 0.3424
Schistosoma mansoni hypothetical protein 0.0976 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0263 0.254 0.254
Leishmania major hypothetical protein, conserved 0.0347 0.3424 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0347 0.3424 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0976 1 0.5
Trypanosoma cruzi WLM domain containing protein, putative 0.0347 0.3424 0.5
Leishmania major hypothetical protein, conserved 0.0347 0.3424 0.5
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0976 1 0.5
Echinococcus multilocularis SWI:SNF matrix associated 0.0976 1 1
Plasmodium vivax hypothetical protein, conserved 0.0976 1 0.5
Onchocerca volvulus 0.0976 1 1
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0347 0.3424 0.5
Echinococcus multilocularis zinc finger protein Ran binding 0.0347 0.3424 0.1186
Schistosoma mansoni TRABID protein (C64 family) 0.0347 0.3424 0.3424
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0976 1 1
Echinococcus granulosus ring and YY1 binding protein 0.0347 0.3424 0.1186
Entamoeba histolytica protein kinase, putative 0.0263 0.254 0.5
Echinococcus multilocularis SWI:SNF matrix associated 0.0976 1 1
Echinococcus multilocularis SWI:SNF matrix associated 0.0976 1 1
Schistosoma mansoni fusion 0.0347 0.3424 0.3424
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0347 0.3424 0.5
Chlamydia trachomatis SWIB complex protein 0.0976 1 0.5
Giardia lamblia Kinase, NEK 0.002 0 0.5
Entamoeba histolytica protein kinase, putative 0.0263 0.254 0.5
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0347 0.3424 0.5
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0976 1 1
Echinococcus granulosus Zinc finger RanBP2 type 0.0347 0.3424 0.1186
Trypanosoma brucei hypothetical protein, conserved 0.0347 0.3424 0.5
Brugia malayi brahma associated protein 60 kDa 0.0976 1 1
Schistosoma mansoni hypothetical protein 0.0976 1 1
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0976 1 1
Trypanosoma cruzi hypothetical protein, conserved 0.0347 0.3424 0.5
Echinococcus granulosus zinc finger protein Ran binding 0.0347 0.3424 0.1186
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0976 1 1
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0263 0.254 0.0001
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0976 1 1
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0976 1 1
Brugia malayi SWIB/MDM2 domain containing protein 0.0976 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0347 0.3424 0.5
Echinococcus multilocularis ring and YY1 binding protein 0.0347 0.3424 0.1186
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0347 0.3424 0.1186
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0347 0.3424 0.5
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0347 0.3424 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0347 0.3424 0.5
Leishmania major hypothetical protein, conserved 0.0347 0.3424 0.5
Schistosoma mansoni hypothetical protein 0.0976 1 1
Schistosoma mansoni brg-1 associated factor 0.0976 1 1
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0347 0.3424 0.1186
Schistosoma mansoni RNA binding protein 0.0347 0.3424 0.3424
Trypanosoma cruzi WLM domain containing protein, putative 0.0347 0.3424 0.5
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0347 0.3424 0.5
Giardia lamblia Kinase, NEK 0.002 0 0.5
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0263 0.254 0.0001
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0347 0.3424 0.5
Leishmania major hypothetical protein, conserved 0.0347 0.3424 0.5
Chlamydia trachomatis DNA topoisomerase I 0.0976 1 0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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