Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0518 | 1 | 1 |
Loa Loa (eye worm) | trypsin family protein | 0.0518 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0518 | 1 | 1 |
Echinococcus multilocularis | Mastin | 0.0518 | 1 | 0.5 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0518 | 1 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0518 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Mycobacterium tuberculosis | Probable acetolactate synthase IlvG (acetohydroxy-acid synthase)(ALS) | 0.0354 | 0.5525 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0518 | 1 | 1 |
Onchocerca volvulus | 0.0518 | 1 | 0.5 | |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0518 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0518 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0518 | 1 | 1 |
Mycobacterium leprae | Probable Acetolactate synthase IlvG (Acetohydroxy-acid synthase)(ALS) | 0.0354 | 0.5525 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0203 | 0.1395 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0518 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxalyl-CoA decarboxylase OxcA | 0.0354 | 0.5525 | 1 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0203 | 0.1395 | 0.5 |
Brugia malayi | Trypsin family protein | 0.0518 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Mycobacterium leprae | PROBABLE ACETOLACTATE SYNTHASE (LARGE SUBUNIT) ILVB (ACETOHYDROXY-ACID SYNTHASE) | 0.0354 | 0.5525 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0518 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0518 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0518 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0518 | 1 | 1 |
Onchocerca volvulus | 0.0518 | 1 | 0.5 | |
Mycobacterium ulcerans | acetolactate synthase 1 catalytic subunit | 0.0354 | 0.5525 | 0.4799 |
Onchocerca volvulus | 0.0518 | 1 | 0.5 | |
Echinococcus granulosus | enteropeptidase | 0.0518 | 1 | 0.5 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0518 | 1 | 1 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0518 | 1 | 0.5 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0518 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Echinococcus granulosus | Mastin | 0.0518 | 1 | 0.5 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0518 | 1 | 0.5 |
Onchocerca volvulus | 0.0518 | 1 | 0.5 | |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0518 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0518 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0518 | 1 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0518 | 1 | 1 |
Leishmania major | putative pyruvate/indole-pyruvate carboxylase, putative | 0.0203 | 0.1395 | 0.5 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0518 | 1 | 0.5 |
Onchocerca volvulus | 0.0518 | 1 | 0.5 | |
Mycobacterium ulcerans | hypothetical protein | 0.0354 | 0.5525 | 0.4799 |
Echinococcus multilocularis | enteropeptidase | 0.0518 | 1 | 0.5 |
Onchocerca volvulus | 0.0518 | 1 | 0.5 | |
Brugia malayi | Trypsin family protein | 0.0518 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0518 | 1 | 1 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0518 | 1 | 0.5 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0518 | 1 | 0.5 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0518 | 1 | 0.5 |
Loa Loa (eye worm) | ILVBL protein | 0.0214 | 0.1716 | 0.0363 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0518 | 1 | 1 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0518 | 1 | 0.5 |
Brugia malayi | hypothetical protein | 0.0518 | 1 | 1 |
Mycobacterium ulcerans | putative oxalyl-CoA decarboxylase | 0.0354 | 0.5525 | 0.4799 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0518 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0518 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.