Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | biogenic amine (octopamine/dopamine) receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Dopamine receptor protein 2 | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | g protein linked acetylcholine receptor gar 2a | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | biogenic amine (5HT) receptor | 0.0033 | 0.0025 | 0.0151 |
Wolbachia endosymbiont of Brugia malayi | dihydrodipicolinate synthase | 0.0113 | 0.0386 | 0.5 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | allatostatin A receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | somatostatin receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | neuropeptide F-like receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | G-protein-linked acetylcholine receptor protein 2, putative | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Serotonin receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | g protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | neuropeptide receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | 7TM GPCR, rhodopsin | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | sex peptide receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | G protein coupled 5 hydroxytryptamine receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | orexin receptor type 2 | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | allatostatin A receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Chlamydia trachomatis | 4-hydroxy-tetrahydrodipicolinate synthase | 0.0113 | 0.0386 | 0.5 |
Schistosoma mansoni | histamine h1 receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | putative neuropeptide receptor NPR1 | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | g protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | follicle stimulating hormone receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | serotonin receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | neuropeptide receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Serotonin receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | dro:myosuppressin receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Echinococcus granulosus | 7TM GPCR rhodopsin | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | neuropeptide s receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Trichomonas vaginalis | dihydrodipicolinate synthase, putative | 0.0113 | 0.0386 | 0.5 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | neuropeptide F receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | G-protein coupled receptor, putative | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | neuropeptide F receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | sex peptide receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | neuropeptide receptor A26 | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | 7tm_1 domain containing protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0033 | 0.0025 | 0.0151 |
Mycobacterium tuberculosis | Malate synthase G GlcB | 0.2253 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | amine GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | tachykinin peptides receptor 99D | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | unidentified vitellogenin-linked transcript protein 6 | 0.0033 | 0.0025 | 0.0151 |
Leishmania major | carbonic anhydrase-like protein | 0.0027 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | serotonin receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | amine GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | somatostatin receptor | 0.0033 | 0.0025 | 0.0151 |
Toxoplasma gondii | dihydrodipicolinate synthase | 0.0113 | 0.0386 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | TYRA-2 protein | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Melatonin receptor type 1A | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0365 | 0.1518 | 0.9352 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | amine GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | g protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | thyrotropin releasing hormone receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | neuropeptide FF receptor 2 | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0389 | 0.1623 | 1 |
Echinococcus multilocularis | neuropeptide receptor A26 | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Serotonin/octopamine receptor family protein 7 | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | dro:myosuppressin receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Tachykinin-like peptides receptor 99D | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Schistosoma mansoni | ancient conserved domain protein 2 (cyclin m2) | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Dopamine receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | neuropeptide f receptor 76f | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | peptide (FMRFamide/somatostatin)-like receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | putative neuropeptide receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | sulfakinin receptor protein | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Echinococcus granulosus | pyroglutamylated rfamide peptide receptor | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | Neuropeptide F receptor homolog | 0.0033 | 0.0025 | 0.5 |
Echinococcus multilocularis | g protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0027 | 0 | 0.5 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0389 | 0.1623 | 1 |
Echinococcus multilocularis | growth hormone secretagogue receptor type 1 | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | thyrotropin-releasing hormone receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | fmrfamide receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | neuropeptide F receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Unidentified vitellogenin-linked transcript protein 6, putative | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | orexin receptor type 2 | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | G protein coupled receptor 139 | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | peptide (allatostatin/somatostatin)-like receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Plasmodium falciparum | carbonic anhydrase | 0.0027 | 0 | 0.5 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0027 | 0 | 0.5 |
Echinococcus granulosus | g protein linked acetylcholine receptor gar 2a | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | biogenic amine receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | opsin-like receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | Dopamine\/Ecdysteroid receptor homolog | 0.0033 | 0.0025 | 0.5 |
Schistosoma mansoni | opsin-like receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | alpha 1A adrenergic receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | neuropeptide Y receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | biogenic amine receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | G protein-coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Schistosoma mansoni | neuropeptide receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0389 | 0.1623 | 1 |
Brugia malayi | AKH receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | Two pore potassium channel protein sup 9 | 0.0389 | 0.1623 | 1 |
Schistosoma mansoni | neuropeptide receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | biogenic amine (dopamine) receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | G-protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | Two pore potassium channel protein sup 9 | 0.0389 | 0.1623 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Twik (KCNK-like) family of potassium channels, alpha subunit 38. C. elegans sup-9 ortholog | 0.0389 | 0.1623 | 1 |
Echinococcus granulosus | g-protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | melatonin receptor type 1A | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | g protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | peptide allatostatin:somatostatin | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | tm gpcr rhodopsin | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | histamine-responsive GPCR (AAF21638) | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | G protein coupled 5 hydroxytryptamine receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | G protein-coupled receptor F59B2.13 | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | peptide (FMRFamide/neurokinin-3)-like receptor | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | g-protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | neuropeptide receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | serotonin receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Dopamine receptor protein 1, putative (partial) | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | larval opioid receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | neuropeptides capa receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | fmrfamide receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | peptide (allatostatin:somatostatin) | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | neuropeptide Y receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | growth hormone secretagogue receptor | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Echinococcus granulosus | thyrotropin releasing hormone receptor | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Schistosoma mansoni | muscarinic acetylcholine (GAR) receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | ORL1-like opioid receptor | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Schistosoma mansoni | amine GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | neuropeptide receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | alpha-1 adrenergic receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | neuropeptide s receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | pyroglutamylated rfamide peptide receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | alpha 1A adrenergic receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | biogenic amine receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | G-protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | neuropeptide receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | G-protein-linked acetylcholine receptor protein 2 | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | g protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | myosin xvIII | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | gonadotropin-releasing hormone receptor 2 | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | 5-hydroxytryptamine 2C receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | gonadotropin-releasing hormone receptor 2 | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | growth hormone secretagogue receptor type 1 | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Schistosoma mansoni | amine GPCR | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Echinococcus multilocularis | fmrfamide receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | neuropeptide FF receptor 2 | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | Dopamine receptor protein 1 | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | peptide (allatostatin)-like receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | tachykinin peptides receptor 99D | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | rhodopsin-like orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Schistosoma mansoni | opsin-like receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | neuropeptide receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | G-protein coupled receptor | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Mycobacterium ulcerans | malate synthase G | 0.2253 | 1 | 1 |
Schistosoma mansoni | adenoreceptor | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Echinococcus granulosus | neuropeptide Y receptor | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Onchocerca volvulus | 0.0033 | 0.0025 | 0.5 | |
Brugia malayi | GnHR receptor homolog | 0.0033 | 0.0025 | 0.0151 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0027 | 0 | 0.5 |
Echinococcus multilocularis | tm gpcr rhodopsin gpcr rhodopsin superfamily | 0.0033 | 0.0025 | 0.0151 |
Echinococcus granulosus | neuropeptides capa receptor | 0.0033 | 0.0025 | 0.0151 |
Echinococcus multilocularis | rhodopsin orphan GPCR | 0.0033 | 0.0025 | 0.0151 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0025 | 0.0151 |
Brugia malayi | RE15519p | 0.0033 | 0.0025 | 0.0151 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
CC50 (functional) | = 0.00000075 M | In vitro cell cytotoxicity was determined against EMT-6 cell line | ChEMBL. | 15027876 |
CC50 (functional) | = 0.0000033 M | In vitro cell cytotoxicity was determined against 143B cell line | ChEMBL. | 15027876 |
CC50 (functional) | = 0.0000048 M | In vitro cell cytotoxicity was determined against Hs 578.Bst cell line | ChEMBL. | 15027876 |
CC50 (functional) | = 0.0000063 M | In vitro cell cytotoxicity was determined against 143B-LTK cell line | ChEMBL. | 15027876 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.