Detailed information for compound 1873163

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 350.454 | Formula: C22H26N2O2
  • H donors: 1 H acceptors: 2 LogP: 3.02 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC[C@@H]1[C@H]2CCN([C@H]2c2c(N1C)ccc(c2)c1ccccc1)C(=O)CC
  • InChi: 1S/C22H26N2O2/c1-3-21(26)24-12-11-17-20(14-25)23(2)19-10-9-16(13-18(19)22(17)24)15-7-5-4-6-8-15/h4-10,13,17,20,22,25H,3,11-12,14H2,1-2H3/t17-,20-,22-/m1/s1
  • InChiKey: CCINGVMSXCWVJW-NQSCKRDGSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Schistosoma mansoni hypothetical protein 0.0009 0.0004 0.0004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0127 0.0995 0.0995
Echinococcus granulosus tar DNA binding protein 0.0055 0.0393 0.0393
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0082 0.0618 0.0618
Echinococcus granulosus neuropeptide receptor 0.0009 0.0004 0.0004
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0009 0.0004 0.0004
Brugia malayi hypothetical protein 0.0013 0.0038 0.0038
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0127 0.0995 0.0995
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0127 0.0995 0.1035
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0127 0.0995 0.0995
Onchocerca volvulus 0.0082 0.0618 0.3001
Loa Loa (eye worm) hypothetical protein 0.0044 0.0293 0.0293
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Giardia lamblia Encystation-specific protease 0.0127 0.0995 0.1035
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0127 0.0995 0.1035
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0127 0.0995 0.1035
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0127 0.0995 0.4735
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0024 0.0131 0.0131
Echinococcus multilocularis cyclins 0.0055 0.0391 0.0391
Schistosoma mansoni nAChR subunit 0.0082 0.0618 0.0618
Echinococcus granulosus glycine receptor subunit beta 0.0082 0.0618 0.0618
Trypanosoma cruzi cysteine proteinase, putative 0.0178 0.1427 0.1394
Loa Loa (eye worm) hypothetical protein 0.003 0.0177 0.0177
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0009 0.0004 0.0004
Echinococcus multilocularis cyclin G2 0.0013 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Mycobacterium ulcerans glutamate racemase 0.0838 0.7 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0082 0.0618 0.0618
Brugia malayi putative neuropeptide receptor 0.0009 0.0004 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0037 0.0241 0.0241
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0663 0.5521 0.5521
Onchocerca volvulus 0.0009 0.0004 0.0018
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0069 0.051 0.051
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Trichomonas vaginalis myo inositol monophosphatase, putative 0.003 0.018 0.0154
Brugia malayi Serotonin receptor 0.0009 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0004 0.0004
Toxoplasma gondii cathepsin CPC1 0.0127 0.0995 0.1035
Schistosoma mansoni tyrosine kinase 0.0016 0.0057 0.0057
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0069 0.051 0.051
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1193 1 1
Giardia lamblia Cathepsin L precursor 0.0127 0.0995 0.1035
Brugia malayi AKH receptor 0.0009 0.0004 0.0004
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0127 0.0995 0.4831
Brugia malayi Cathepsin L-like precursor 0.0253 0.206 0.206
Brugia malayi RE15519p 0.0009 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0009 0.0004 0.0004
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0127 0.0995 0.4735
Loa Loa (eye worm) hypothetical protein 0.0127 0.0995 0.0995
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Echinococcus multilocularis cyclin A3 4 0.0013 0.0038 0.0038
Leishmania major cathepsin L-like protease 0.0253 0.206 0.2187
Loa Loa (eye worm) hypothetical protein 0.0051 0.0357 0.0357
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Giardia lamblia Cysteine protease 0.0127 0.0995 0.1035
Schistosoma mansoni proteasome subunit alpha 1 (T01 family) 0.0013 0.0038 0.0038
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0038 0.0245 0.0245
Loa Loa (eye worm) inositol-1 0.003 0.018 0.018
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis cyclins 0.0055 0.0391 0.0391
Schistosoma mansoni nAChR subunit 0.0038 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0009 0.0004 0.0004
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0061 0.0437 0.0437
Loa Loa (eye worm) hypothetical protein 0.0127 0.0995 0.0995
Plasmodium vivax serine-repeat antigen (SERA) 0.0127 0.0995 0.4735
Echinococcus granulosus cathepsin L 0.0178 0.1427 0.1427
Echinococcus granulosus cathepsin l cysteine peptidase 0.0253 0.206 0.206
Giardia lamblia G2/mitotic-specific cyclin B 0.0055 0.0391 0.0382
Echinococcus multilocularis survival motor neuron protein 1 0.0207 0.1669 0.1669
Onchocerca volvulus 0.0009 0 0.0002
Brugia malayi hypothetical protein 0.0139 0.11 0.11
Loa Loa (eye worm) cyclin domain-containing protein 0.0013 0.0038 0.0038
Entamoeba histolytica cyclin, domain containing protein 0.0013 0.0038 0.0182
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.1109 0.9285 1
Brugia malayi Dopamine receptor protein 2 0.0009 0.0004 0.0004
Echinococcus multilocularis allatostatin A receptor 0.0009 0.0004 0.0004
Echinococcus granulosus peptide allatostatin:somatostatin 0.0009 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0004 0.0004
Brugia malayi follicle stimulating hormone receptor 0.0196 0.1582 0.1582
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0127 0.0995 0.1035
Echinococcus multilocularis tyrosine protein kinase Srms 0.0063 0.0453 0.0453
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0253 0.206 0.2187
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Plasmodium falciparum cyclin 0.0055 0.0391 0.1747
Brugia malayi Papain family cysteine protease containing protein 0.0253 0.206 0.206
Echinococcus granulosus allatostatin A receptor 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Loa Loa (eye worm) neuropeptide F receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) fibroinase 0.0253 0.206 0.206
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0009 0.0004 0.0004
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0178 0.1427 0.1427
Schistosoma mansoni acetylcholine receptor subunit beta 0.0038 0.0245 0.0245
Schistosoma mansoni neurotransmitter gated ion channel 0.0038 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Schistosoma mansoni neuropeptide F-like receptor 0.0009 0.0004 0.0004
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0009 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0004 0.0004
Echinococcus granulosus cdk5 and abl1 enzyme substrate 1 0.0013 0.0038 0.0038
Echinococcus multilocularis fmrfamide receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis neuropeptide Y receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0044 0.0299 0.0299
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0253 0.206 1
Brugia malayi Cathepsin L-like precursor 0.0253 0.206 0.206
Trichomonas vaginalis cyclin B, putative 0.0055 0.0391 0.0382
Echinococcus multilocularis cysteine protease 0.0253 0.206 0.206
Onchocerca volvulus Cathepsin L homolog 0.0127 0.0995 0.4832
Brugia malayi Cation transporter family protein 0.0082 0.0618 0.0618
Loa Loa (eye worm) LGC-31 protein 0.0082 0.0618 0.0618
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0082 0.0618 0.0618
Onchocerca volvulus 0.0082 0.0618 0.3001
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0618 0.0618
Brugia malayi Sex muscle abnormal protein 5 0.0014 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0082 0.0618 0.0618
Trichomonas vaginalis cyclins, putative 0.0055 0.0391 0.0382
Echinococcus multilocularis G protein coupled receptor 139 0.0009 0.0004 0.0004
Schistosoma mansoni cyclin k 0.0013 0.0038 0.0038
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0024 0.0131 0.0131
Plasmodium vivax serine-repeat antigen (SERA) 0.0127 0.0995 0.4735
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.017 0.1362 0.1362
Onchocerca volvulus 0.0009 0.0004 0.0018
Trichomonas vaginalis cyclin A, putative 0.0055 0.0391 0.0382
Entamoeba histolytica protein kinase, putative 0.0056 0.0395 0.1915
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0004 0.0004
Brugia malayi Melatonin receptor type 1A 0.0009 0.0004 0.0004
Schistosoma mansoni nAChR subunit 0.0082 0.0618 0.0618
Echinococcus granulosus cysteine protease 0.0178 0.1427 0.1427
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0082 0.0618 0.0618
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.003 0.018 0.0154
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1193 1 1
Brugia malayi latrophilin 2 splice variant baaae 0.003 0.0177 0.0177
Schistosoma mansoni hypothetical protein 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0253 0.206 0.2187
Plasmodium falciparum serine repeat antigen 3 0.0127 0.0995 0.4735
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Mycobacterium tuberculosis Probable glutamate racemase MurI 0.0838 0.7 1
Onchocerca volvulus 0.0127 0.0995 0.4832
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.018 0.0154
Brugia malayi Latrophilin receptor protein 2 0.0014 0.0042 0.0042
Schistosoma mansoni opsin-like receptor 0.0009 0.0004 0.0004
Plasmodium falciparum serine repeat antigen 5 0.0127 0.0995 0.4735
Echinococcus granulosus growth factor receptor bound protein 2 0.0014 0.0041 0.0041
Trypanosoma cruzi cruzipain precursor, putative 0.0253 0.206 0.203
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.0618 0.0618
Loa Loa (eye worm) cyclin domain-containing protein 0.0013 0.0038 0.0038
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0016 0.0057 0.0057
Brugia malayi Dopamine receptor protein 1 0.0009 0.0004 0.0004
Onchocerca volvulus 0.0009 0.0004 0.0018
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0618 0.0618
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0004 0.0004
Echinococcus granulosus neuropeptide Y receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis inositol monophosphatase 1 0.003 0.018 0.018
Brugia malayi cathepsin L-like precursor 0.0202 0.1628 0.1628
Trypanosoma cruzi major cysteine proteinase, putative 0.0127 0.0995 0.0961
Giardia lamblia Cathepsin B precursor 0.1109 0.9285 1
Plasmodium falciparum serine repeat antigen 6 0.0127 0.0995 0.4735
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis dro:myosuppressin receptor 0.0009 0.0004 0.0004
Trichomonas vaginalis cyclin B, putative 0.0055 0.0391 0.0382
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0178 0.1427 0.1502
Brugia malayi Dopamine receptor 0.0009 0.0004 0.0004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Schistosoma mansoni hypothetical protein 0.0009 0.0004 0.0004
Loa Loa (eye worm) CYL-1 protein 0.0013 0.0038 0.0038
Echinococcus granulosus tyrosine protein kinase Fyn 0.0069 0.051 0.051
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Loa Loa (eye worm) neuropeptide F receptor 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0178 0.1427 0.6927
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0127 0.0995 0.4735
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0127 0.0995 0.1035
Echinococcus multilocularis fmrfamide receptor 0.0009 0.0004 0.0004
Schistosoma mansoni biogenic amine receptor 0.0009 0.0004 0.0004
Schistosoma mansoni biogenic amine receptor 0.0009 0.0004 0.0004
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0037 0.0241 0.0241
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0082 0.0618 0.0618
Echinococcus granulosus cyclin k 0.0013 0.0038 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0202 0.1628 0.172
Schistosoma mansoni biogenic amine (5HT) receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0044 0.0299 0.0299
Onchocerca volvulus 0.0009 0 0.0002
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0069 0.051 0.051
Plasmodium vivax vivapain-1 0.0178 0.1427 0.687
Echinococcus granulosus tyrosine protein kinase Src42A 0.0069 0.051 0.051
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Echinococcus granulosus survival motor neuron protein 1 0.0207 0.1669 0.1669
Brugia malayi Cathepsin L-like precursor 0.0202 0.1628 0.1628
Schistosoma mansoni hypothetical protein 0.0042 0.0281 0.0281
Echinococcus multilocularis glycine receptor subunit beta 0.0082 0.0618 0.0618
Schistosoma mansoni cyclin B3 0.0055 0.0391 0.0391
Echinococcus multilocularis cyclin y 0.0013 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0139 0.11 0.11
Trypanosoma cruzi cysteine protease, putative 0.0178 0.1427 0.1394
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0082 0.0618 0.0618
Loa Loa (eye worm) G-protein coupled receptor 0.0009 0.0004 0.0004
Onchocerca volvulus 0.0253 0.206 1
Plasmodium falciparum serine repeat antigen 9 0.0127 0.0995 0.4735
Leishmania major cathepsin L-like protease 0.0253 0.206 0.2187
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Schistosoma mansoni inositol monophosphatase 0.003 0.018 0.018
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0009 0.0004 0.0004
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0044 0.0293 0.0293
Echinococcus granulosus neuropeptide receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0009 0.0004 0.0004
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0082 0.0618 0.0618
Entamoeba histolytica cyclin family protein 0.0055 0.0391 0.1897
Echinococcus granulosus tyrosine protein kinase HCK 0.0056 0.0395 0.0395
Echinococcus multilocularis tyrosine protein kinase HCK 0.0056 0.0395 0.0395
Echinococcus granulosus Cyclin L1 0.0013 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Brugia malayi excitatory GABA receptor EXP-1A 0.0082 0.0618 0.0618
Brugia malayi Papain family cysteine protease containing protein 0.0178 0.1427 0.1427
Entamoeba histolytica cysteine proteinase, putative 0.0253 0.206 1
Loa Loa (eye worm) hypothetical protein 0.0044 0.0299 0.0299
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0127 0.0995 0.4735
Echinococcus granulosus cyclins 0.0013 0.0038 0.0038
Loa Loa (eye worm) GABA receptor subunit 0.0044 0.0299 0.0299
Onchocerca volvulus 0.0009 0 0.0002
Schistosoma mansoni amine GPCR 0.0009 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0178 0.1427 0.1502
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0391 0.0382
Brugia malayi Cathepsin L-like precursor 0.0253 0.206 0.206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Trichomonas vaginalis set domain proteins, putative 0.0194 0.156 0.1646
Loa Loa (eye worm) hypothetical protein 0.0044 0.0299 0.0299
Plasmodium falciparum cysteine proteinase falcipain 1 0.0178 0.1427 0.687
Onchocerca volvulus 0.0009 0.0004 0.0018
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0024 0.0124 0.0124
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0004 0.0004
Schistosoma mansoni cyclin l 0.0013 0.0038 0.0038
Trypanosoma cruzi major cysteine proteinase, putative 0.0127 0.0995 0.0961
Schistosoma mansoni transcription factor LCR-F1 0.0029 0.0174 0.0174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Toxoplasma gondii cathepsin B 0.1109 0.9285 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Echinococcus granulosus cyclin G2 0.0013 0.0038 0.0038
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0082 0.0618 0.0618
Onchocerca volvulus 0.0253 0.206 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0009 0.0004 0.0004
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0082 0.0618 0.0618
Onchocerca volvulus 0.0038 0.0245 0.1189
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0082 0.0618 0.0618
Trichomonas vaginalis cyclin B, putative 0.0055 0.0391 0.0382
Entamoeba histolytica hypothetical protein 0.0044 0.0299 0.1448
Brugia malayi hypothetical protein 0.0038 0.0245 0.0245
Schistosoma mansoni tar DNA-binding protein 0.0055 0.0393 0.0393
Brugia malayi hypothetical protein 0.0013 0.0038 0.0038
Echinococcus multilocularis cyclin G2 0.0013 0.0038 0.0038
Echinococcus granulosus cyclins 0.0055 0.0391 0.0391
Brugia malayi G protein-coupled receptor 0.0009 0.0004 0.0004
Plasmodium vivax vivapain-3 0.0178 0.1427 0.687
Loa Loa (eye worm) cathepsin B 0.1109 0.9285 0.9285
Echinococcus multilocularis cyclin k 0.0013 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0253 0.206 0.2187
Brugia malayi cathepsin F-like cysteine proteinase 0.0051 0.0357 0.0357
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0253 0.206 1
Echinococcus granulosus tyrosine protein kinase Src42A 0.0061 0.0437 0.0437
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0127 0.0995 0.4735
Loa Loa (eye worm) hypothetical protein 0.0014 0.0042 0.0042
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Giardia lamblia Cathepsin L-like protease 0.0127 0.0995 0.1035
Entamoeba histolytica hypothetical protein 0.0029 0.0174 0.0842
Trichomonas vaginalis myo inositol monophosphatase, putative 0.003 0.018 0.0154
Schistosoma mansoni tyrosine kinase 0.0069 0.051 0.051
Brugia malayi cathepsin Z-like cysteine proteinase 0.0127 0.0995 0.0995
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0009 0.0004 0.0004
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0038 0.0245 0.0245
Brugia malayi putative neuropeptide receptor NPR1 0.0009 0.0004 0.0004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1193 1 1
Echinococcus multilocularis G1:S specific cyclin D1 0.0013 0.0038 0.0038
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0069 0.051 0.051
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0253 0.206 0.2187
Loa Loa (eye worm) hypothetical protein 0.0127 0.0995 0.0995
Schistosoma mansoni nck2/grb4 0.0014 0.0041 0.0041
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0014 0.0041 0.0041
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Brugia malayi neuropeptide F receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis cyclin b3 0.0055 0.0391 0.0391
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Giardia lamblia Cathepsin B precursor 0.0127 0.0995 0.1035
Trypanosoma brucei mitotic cyclin 6 0.0055 0.0391 0.0382
Giardia lamblia Cathepsin B precursor 0.0127 0.0995 0.1035
Echinococcus multilocularis nAChR subunit 0.0044 0.0299 0.0299
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0038 0.0245 0.0245
Echinococcus multilocularis GPCR, family 2 0.0014 0.0042 0.0042
Brugia malayi Cyclin, N-terminal domain containing protein 0.0013 0.0038 0.0038
Echinococcus multilocularis cyclins 0.0055 0.0391 0.0391
Onchocerca volvulus Cathepsin L homolog 0.0253 0.206 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0127 0.0995 0.4735
Loa Loa (eye worm) ctsf protein 0.0253 0.206 0.206
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Echinococcus granulosus histone lysine methyltransferase setb 0.0024 0.0131 0.0131
Onchocerca volvulus Cyclin L homolog 0.0013 0.0038 0.0184
Echinococcus granulosus cyclin b3 0.0055 0.0391 0.0391
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Brugia malayi Cathepsin L-like precursor 0.0051 0.0357 0.0357
Onchocerca volvulus Cyclin L homolog 0.0013 0.0038 0.0184
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0127 0.0995 0.1035
Echinococcus multilocularis cathepsin L cysteine protease 0.0253 0.206 0.206
Entamoeba histolytica cysteine protease, putative 0.0127 0.0995 0.4831
Loa Loa (eye worm) hypothetical protein 0.0055 0.0391 0.0391
Schistosoma mansoni histamine h1 receptor 0.0009 0.0004 0.0004
Brugia malayi Cyclin, N-terminal domain containing protein 0.0055 0.0391 0.0391
Schistosoma mansoni cathepsin S (C01 family) 0.0127 0.0995 0.0995
Echinococcus granulosus tm gpcr rhodopsin 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Brugia malayi Tachykinin-like peptides receptor 99D 0.0009 0.0004 0.0004
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0178 0.1427 0.1427
Echinococcus granulosus cathepsin l1 0.0202 0.1628 0.1628
Echinococcus multilocularis cyclins 0.0055 0.0391 0.0391
Echinococcus granulosus cyclins 0.0055 0.0391 0.0391
Echinococcus granulosus tyrosine protein kinase Src64B 0.0069 0.051 0.051
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0082 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Loa Loa (eye worm) MH2 domain-containing protein 0.0116 0.0903 0.0903
Onchocerca volvulus 0.0009 0.0004 0.0018
Trypanosoma cruzi cysteine peptidase, putative 0.0051 0.0357 0.032
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0253 0.206 0.206
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0082 0.0618 0.0618
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0038 0.0245 0.0245
Onchocerca volvulus 0.0082 0.0618 0.3001
Schistosoma mansoni tyrosine kinase 0.0069 0.051 0.051
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0051 0.0357 0.0357
Echinococcus multilocularis cathepsin L 0.0127 0.0995 0.0995
Echinococcus granulosus cyclins 0.0055 0.0391 0.0391
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0024 0.0131 0.0131
Brugia malayi G-protein coupled receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Onchocerca volvulus 0.0194 0.156 0.7573
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0082 0.0618 0.0618
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Schistosoma mansoni cathepsin B (C01 family) 0.0127 0.0995 0.0995
Plasmodium vivax unspecified product 0.0127 0.0995 0.4735
Schistosoma mansoni cathepsin F (C01 family) 0.0253 0.206 0.206
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0009 0.0004 0.0004
Leishmania major cyclin 0.0055 0.0391 0.0382
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0127 0.0995 0.4831
Schistosoma mansoni cyclin G2 0.0013 0.0038 0.0038
Leishmania major cathepsin L-like protease 0.0253 0.206 0.2187
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0009 0.0004 0.0004
Trypanosoma cruzi cysteine proteinase, putative 0.0178 0.1427 0.1394
Loa Loa (eye worm) cyclin C 0.0013 0.0038 0.0038
Schistosoma mansoni neurotransmitter gated ion channel 0.0038 0.0245 0.0245
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0009 0.0004 0.0004
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0082 0.0618 0.0618
Brugia malayi Cation transporter family protein 0.0082 0.0618 0.0618
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.0618 0.0618
Plasmodium falciparum serine repeat antigen 7 0.0127 0.0995 0.4735
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0082 0.0618 0.0618
Echinococcus multilocularis G-protein coupled receptor, putative 0.0009 0.0004 0.0004
Schistosoma mansoni neuropeptide receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus granulosus cyclin y 0.0013 0.0038 0.0038
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0127 0.0995 0.1035
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0038 0.0245 0.0245
Schistosoma mansoni neuropeptide F-like receptor 0.0009 0.0004 0.0004
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0082 0.0618 0.0618
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0014 0.0042 0.0042
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Echinococcus multilocularis cyclin y 0.0013 0.0038 0.0038
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0024 0.0131 0.0101
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0082 0.0618 0.0618
Echinococcus granulosus tyrosine kinase 0.0063 0.0453 0.0453
Brugia malayi Cyclin, N-terminal domain containing protein 0.0055 0.0391 0.0391
Echinococcus granulosus G protein coupled receptor 139 0.0009 0.0004 0.0004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0004 0.0004
Brugia malayi GnHR receptor homolog 0.0009 0.0004 0.0004
Echinococcus multilocularis cyclins 0.0055 0.0391 0.0391
Entamoeba histolytica myo-inositol monophosphatase, putative 0.003 0.018 0.0874
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0024 0.0131 0.0131
Entamoeba histolytica cysteine protease, putative 0.0127 0.0995 0.4831
Brugia malayi Inositol-1 0.003 0.018 0.018
Loa Loa (eye worm) cyclin domain-containing protein 0.0013 0.0038 0.0038
Brugia malayi larval opioid receptor 0.0009 0.0004 0.0004
Schistosoma mansoni neuropeptide receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis cdk5 and abl1 enzyme substrate 1 0.0013 0.0038 0.0038
Echinococcus granulosus tyrosine protein kinase Fyn 0.0069 0.051 0.051
Schistosoma mansoni acetylcholine receptor-related 0.0038 0.0245 0.0245
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0082 0.0618 0.0618
Schistosoma mansoni Cyclin fold protein 0.0013 0.0038 0.0038
Brugia malayi hypothetical protein 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0055 0.0391 0.0391
Brugia malayi fibroinase precursor 0.0127 0.0995 0.0995
Onchocerca volvulus 0.0253 0.206 1
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0044 0.0299 0.0299
Schistosoma mansoni growth factor receptor-bound protein 0.0014 0.0041 0.0041
Giardia lamblia Cysteine protease 0.0127 0.0995 0.1035
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Giardia lamblia Hypothetical protein 0.0127 0.0995 0.1035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0038 0.0245 0.0245
Loa Loa (eye worm) acetylcholine receptor protein 0.0038 0.0245 0.0245
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1109 0.9285 0.9285
Schistosoma mansoni neuropeptide receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis neuropeptide receptor 0.0009 0.0004 0.0004
Echinococcus granulosus tyrosine protein kinase Lyn 0.0069 0.051 0.051
Plasmodium vivax unspecified product 0.0051 0.0357 0.1579
Echinococcus granulosus glycine receptor subunit alpha 1 0.0082 0.0618 0.0618
Onchocerca volvulus 0.0253 0.206 1
Loa Loa (eye worm) transcription factor SMAD2 0.0116 0.0903 0.0903
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0196 0.1582 0.1582
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0051 0.0357 0.0357
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0014 0.0042 0.0042
Echinococcus granulosus neuropeptide FF receptor 2 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0253 0.206 1
Echinococcus multilocularis somatostatin receptor 0.0009 0.0004 0.0004
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.003 0.018 0.0154
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0082 0.0618 0.0618
Schistosoma mansoni hypothetical protein 0.0014 0.0042 0.0042
Echinococcus multilocularis cyclins 0.0055 0.0391 0.0391
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0127 0.0995 0.4735
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0038 0.0245 0.0245
Echinococcus multilocularis cyclin t1 0.0013 0.0038 0.0038
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Brugia malayi hypothetical protein 0.0009 0.0004 0.0004
Entamoeba histolytica cyclin C, putative 0.0013 0.0038 0.0182
Brugia malayi Cyclin, N-terminal domain containing protein 0.0013 0.0038 0.0038
Schistosoma mansoni amine GPCR 0.0009 0.0004 0.0004
Echinococcus granulosus sex peptide receptor 0.0009 0.0004 0.0004
Brugia malayi cathepsin L precursor 0.0127 0.0995 0.0995
Brugia malayi Cyclin, N-terminal domain containing protein 0.0055 0.0391 0.0391
Brugia malayi cathepsin Z-like cysteine proteinase 0.0127 0.0995 0.0995
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0044 0.0299 0.0299
Brugia malayi Pre-SET motif family protein 0.0024 0.0131 0.0131
Onchocerca volvulus 0.0009 0.0004 0.0018
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0618 0.0618
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0038 0.0245 0.0245
Echinococcus multilocularis neuropeptide s receptor 0.0383 0.3161 0.3161
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) cyclin domain-containing protein 0.0055 0.0391 0.0391
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0127 0.0995 0.0995
Loa Loa (eye worm) hypothetical protein 0.0044 0.0299 0.0299
Treponema pallidum glutamate racemase 0.0838 0.7 0.5
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0127 0.0995 0.1035
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0004 0.0004
Echinococcus granulosus somatostatin receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0202 0.1628 0.1628
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0995 0.1035
Trypanosoma cruzi cysteine peptidase, putative 0.0253 0.206 0.203
Echinococcus multilocularis cyclin 0.0013 0.0038 0.0038
Echinococcus granulosus rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0424 0.3507 0.3507
Schistosoma mansoni tar DNA-binding protein 0.0055 0.0393 0.0393
Brugia malayi Cyclin, N-terminal domain containing protein 0.0013 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Echinococcus granulosus cathepsin b 0.1193 1 1
Brugia malayi MH2 domain containing protein 0.0116 0.0903 0.0903
Trichomonas vaginalis cyclins, putative 0.0055 0.0391 0.0382
Brugia malayi hypothetical protein 0.0038 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Schistosoma mansoni nAChR subunit 0.0082 0.0618 0.0618
Schistosoma mansoni myosin xvIII 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0127 0.0995 0.1035
Schistosoma mansoni neuropeptide receptor 0.0009 0.0004 0.0004
Schistosoma mansoni biogenic amine (5HT) receptor 0.0009 0.0004 0.0004
Onchocerca volvulus Putative nachr subunit 0.0082 0.0618 0.3001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0127 0.0995 0.1035
Onchocerca volvulus 0.0044 0.0299 0.145
Brugia malayi Serotonin receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) ACC-1 protein 0.0082 0.0618 0.0618
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0055 0.0391 0.0391
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Giardia lamblia Cathepsin L precursor 0.0127 0.0995 0.1035
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0029 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0127 0.0995 0.1035
Echinococcus granulosus tachykinin peptides receptor 99D 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0127 0.0995 0.1035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0127 0.0995 0.1035
Leishmania major cathepsin L-like protease 0.0253 0.206 0.2187
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0127 0.0995 0.0995
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0004 0.0004
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0016 0.0057 0.0057
Brugia malayi hypothetical protein 0.0009 0.0004 0.0004
Leishmania major cathepsin L-like protease 0.0253 0.206 0.2187
Schistosoma mansoni tyrosine kinase 0.0016 0.0057 0.0057
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0127 0.0995 0.1035
Echinococcus granulosus cyclin A3 4 0.0013 0.0038 0.0038
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0016 0.0057 0.0057
Onchocerca volvulus 0.0044 0.0299 0.145
Onchocerca volvulus 0.0042 0.0281 0.1365
Brugia malayi Papain family cysteine protease containing protein 0.0127 0.0995 0.0995
Schistosoma mansoni inositol monophosphatase 0.003 0.018 0.018
Echinococcus granulosus nAChR subunit 0.0044 0.0299 0.0299
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus granulosus GPCR family 2 0.0014 0.0042 0.0042
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0127 0.0995 0.0995
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0127 0.0995 0.1035
Entamoeba histolytica cysteine proteinase, putative 0.0178 0.1427 0.6927
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1193 1 1
Trypanosoma cruzi CYC2-like cyclin, putative 0.0055 0.0391 0.0355
Trypanosoma cruzi cyclin, putative 0.0055 0.0391 0.0355
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0127 0.0995 0.0995
Brugia malayi Tyrosine-protein kinase abl-1 0.0016 0.0057 0.0057
Brugia malayi G-protein coupled receptor 0.0009 0.0004 0.0004
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0127 0.0995 0.0995
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0082 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0202 0.1628 0.1597
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0009 0.0004 0.0004
Toxoplasma gondii cathepsin CPC2 0.0127 0.0995 0.1035
Onchocerca volvulus 0.0253 0.206 1
Schistosoma mansoni nAChR subunit 0.0082 0.0618 0.0618
Echinococcus granulosus oligomeric golgi complex subunit 3 0.0013 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0082 0.0618 0.0618
Loa Loa (eye worm) ACC-1 protein 0.0082 0.0618 0.0618
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0044 0.0299 0.0299
Entamoeba histolytica cyclin, putative 0.0055 0.0391 0.1897
Echinococcus granulosus neuropeptides capa receptor 0.0009 0.0004 0.0004
Schistosoma mansoni cyclin B 0.0055 0.0391 0.0391
Loa Loa (eye worm) TAR-binding protein 0.0055 0.0393 0.0393
Plasmodium vivax vivapain-2 0.0253 0.206 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0127 0.0995 0.1035
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0038 0.0245 0.0245
Echinococcus granulosus cathepsin L 0.0127 0.0995 0.0995
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Trichomonas vaginalis inositol monophosphatase, putative 0.003 0.018 0.0154
Echinococcus granulosus tyrosine protein kinase Fyn 0.0069 0.051 0.051
Echinococcus multilocularis neuropeptides capa receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0009 0.0004 0.0004
Onchocerca volvulus 0.0009 0.0004 0.0018
Trichomonas vaginalis cyclins, putative 0.0055 0.0391 0.0382
Echinococcus multilocularis orexin receptor type 2 0.0009 0.0004 0.0004
Loa Loa (eye worm) cysteine protease 0.0253 0.206 0.206
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0069 0.051 0.051
Brugia malayi hypothetical protein 0.0009 0.0004 0.0004
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0044 0.0299 0.0299
Loa Loa (eye worm) SRC-1 0.0069 0.051 0.051
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0082 0.0618 0.0618
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0029 0.0174 0.0842
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0127 0.0995 0.4735
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Echinococcus granulosus orexin receptor type 2 0.0009 0.0004 0.0004
Brugia malayi G protein-coupled receptor F59B2.13 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Echinococcus granulosus cyclin B 0.0055 0.0391 0.0391
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.003 0.018 0.5
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0014 0.0041 0.0041
Onchocerca volvulus 0.0082 0.0618 0.3001
Plasmodium vivax SET domain protein, putative 0.0024 0.0131 0.0463
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0127 0.0995 0.1035
Brugia malayi Pre-SET motif family protein 0.017 0.1362 0.1362
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Echinococcus multilocularis neuropeptide FF receptor 2 0.0009 0.0004 0.0004
Onchocerca volvulus 0.0253 0.206 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0037 0.0241 0.0241
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0014 0.0042 0.0042
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0038 0.0245 0.0245
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0127 0.0995 0.0995
Trypanosoma cruzi cysteine peptidase, putative 0.0253 0.206 0.203
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0004 0.0004
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0082 0.0618 0.0618
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0127 0.0995 0.4831
Loa Loa (eye worm) TK protein kinase 0.0063 0.0453 0.0453
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0253 0.206 0.206
Echinococcus multilocularis tar DNA binding protein 0.0055 0.0393 0.0393
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0069 0.051 0.051
Schistosoma mansoni neurotransmitter gated ion channel 0.0044 0.0299 0.0299
Onchocerca volvulus 0.0009 0.0004 0.0018
Schistosoma mansoni cyclin G 0.0013 0.0038 0.0038
Toxoplasma gondii cathepsin CPL 0.0253 0.206 0.2187
Echinococcus multilocularis cyclin B 0.0055 0.0391 0.0391
Echinococcus multilocularis g-protein coupled receptor 0.0009 0.0004 0.0004
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0618 0.0618
Schistosoma mansoni survival motor neuron protein 0.0042 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Brugia malayi Cathepsin L-like precursor 0.0253 0.206 0.206
Echinococcus multilocularis cathepsin L cysteine protease 0.0253 0.206 0.206
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine proteinase 2 0.0178 0.1427 0.6927
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0038 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Schistosoma mansoni nAChR subunit 0.0082 0.0618 0.0618
Brugia malayi Cathepsin L-like precursor 0.0202 0.1628 0.1628
Brugia malayi cathepsin L-like cysteine proteinase 0.0127 0.0995 0.0995
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Echinococcus multilocularis cysteine protease 0.0253 0.206 0.206
Schistosoma mansoni opsin-like receptor 0.0009 0.0004 0.0004
Trichomonas vaginalis cyclins, putative 0.0055 0.0391 0.0382
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0127 0.0995 0.4831
Schistosoma mansoni nAChR subunit 0.0038 0.0245 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Onchocerca volvulus 0.0009 0.0004 0.0018
Brugia malayi hypothetical protein 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Loa Loa (eye worm) hypothetical protein 0.0127 0.0995 0.0995
Brugia malayi hypothetical protein 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Echinococcus granulosus cyclin G2 0.0013 0.0038 0.0038
Echinococcus granulosus cyclin y 0.0013 0.0038 0.0038
Entamoeba histolytica hypothetical protein 0.0029 0.0174 0.0842
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0024 0.0131 0.0131
Echinococcus granulosus glycine receptor subunit alpha 1 0.0082 0.0618 0.0618
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Loa Loa (eye worm) G-protein coupled receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) cyclin domain-containing protein 0.0013 0.0038 0.0038
Brugia malayi hypothetical protein 0.0009 0.0004 0.0004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.018 0.0143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0127 0.0995 0.1035
Loa Loa (eye worm) hypothetical protein 0.0253 0.206 0.206
Brugia malayi cyclin fold protein 1 variant b 0.0013 0.0038 0.0038
Echinococcus multilocularis tyrosine protein kinase Blk 0.0063 0.0453 0.0453
Brugia malayi Cathepsin L-like precursor 0.0253 0.206 0.206
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0082 0.0618 0.0618
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0178 0.1427 0.1394
Echinococcus multilocularis geminin 0.0424 0.3507 0.3507
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Trypanosoma cruzi cysteine peptidase, putative 0.0178 0.1427 0.1394
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0127 0.0995 0.1035
Onchocerca volvulus 0.0009 0.0004 0.0018
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0618 0.0618
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0009 0.0004 0.0004
Trichomonas vaginalis cyclin D, putative 0.0055 0.0391 0.0382
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0082 0.0618 0.0618
Echinococcus multilocularis serotonin receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) cyclin domain-containing protein 0.0013 0.0038 0.0038
Echinococcus granulosus neuropeptide receptor A26 0.0383 0.3161 0.3161
Loa Loa (eye worm) hypothetical protein 0.0207 0.1669 0.1669
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus multilocularis growth factor receptor bound protein 2 0.0014 0.0041 0.0041
Schistosoma mansoni cyclin d 0.0013 0.0038 0.0038
Onchocerca volvulus 0.0009 0.0004 0.0018
Onchocerca volvulus 0.0009 0.0004 0.0018
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0042 0.0281 0.0281
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0004 0.0004
Onchocerca volvulus 0.0013 0.0038 0.0184
Brugia malayi RNA recognition motif domain containing protein 0.0055 0.0393 0.0393
Brugia malayi Cyclin, N-terminal domain containing protein 0.0013 0.0038 0.0038
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0024 0.0131 0.0131
Entamoeba histolytica cysteine protease, putative 0.0127 0.0995 0.4831
Onchocerca volvulus Protein CNPPD1 homolog 0.0013 0.0038 0.0184
Brugia malayi ORL1-like opioid receptor 0.0009 0.0004 0.0004
Schistosoma mansoni g1/s-specific cyclin C 0.0013 0.0038 0.0038
Onchocerca volvulus 0.0055 0.0391 0.1898
Schistosoma mansoni hypothetical protein 0.0424 0.3507 0.3507
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0253 0.206 0.2187
Echinococcus granulosus G1:S specific cyclin D1 0.0013 0.0038 0.0038
Brugia malayi hypothetical protein 0.0038 0.0245 0.0245
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1109 0.9285 0.9282
Onchocerca volvulus Cathepsin F homolog 0.0253 0.206 1
Brugia malayi sulfakinin receptor protein 0.0009 0.0004 0.0004
Echinococcus granulosus cathepsin L cysteine protease 0.0178 0.1427 0.1427
Giardia lamblia Hypothetical protein 0.0055 0.0391 0.0382
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0253 0.206 0.2187
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Brugia malayi hypothetical protein 0.0029 0.0174 0.0174
Schistosoma mansoni tar DNA-binding protein 0.0055 0.0393 0.0393
Trichomonas vaginalis cyclin B3, putative 0.0055 0.0391 0.0382
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0044 0.0299 0.0299
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Echinococcus multilocularis Cyclin L1 0.0013 0.0038 0.0038
Onchocerca volvulus Huntingtin homolog 0.0139 0.11 0.5341
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0082 0.0618 0.0618
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Plasmodium falciparum serine repeat antigen 4 0.0127 0.0995 0.4735
Trypanosoma cruzi cyclin 6, putative 0.0055 0.0391 0.0355
Schistosoma mansoni tar DNA-binding protein 0.0055 0.0393 0.0393
Echinococcus granulosus cathepsin l1 0.0253 0.206 0.206
Echinococcus granulosus nAChR subunit 0.0082 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Echinococcus multilocularis neuropeptide receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Schistosoma mansoni growth factor receptor-bound protein 0.0014 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0013 0.0038 0.0038
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0253 0.206 0.2187
Loa Loa (eye worm) hypothetical protein 0.0139 0.11 0.11
Brugia malayi Cyclin C 0.0013 0.0038 0.0038
Schistosoma mansoni biogenic amine receptor 0.0009 0.0004 0.0004
Giardia lamblia Cathepsin B precursor 0.1109 0.9285 1
Giardia lamblia Cathepsin B precursor 0.1109 0.9285 1
Echinococcus granulosus cyclins 0.0055 0.0391 0.0391
Schistosoma mansoni cathepsin F (C01 family) 0.0202 0.1628 0.1628
Echinococcus granulosus cyclins 0.0055 0.0391 0.0391
Onchocerca volvulus 0.0202 0.1628 0.7905
Echinococcus granulosus glycine receptor subunit alpha 1 0.0082 0.0618 0.0618
Entamoeba histolytica hypothetical protein 0.0127 0.0995 0.4831
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0178 0.1427 0.1502
Trypanosoma cruzi cysteine peptidase, putative 0.0253 0.206 0.203
Giardia lamblia Cysteine protease 0.0127 0.0995 0.1035
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Echinococcus multilocularis c src tyrosine kinase 0.0016 0.0057 0.0057
Schistosoma mansoni amine GPCR 0.0009 0.0004 0.0004
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0082 0.0618 0.0618
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0055 0.0393 0.0393
Trypanosoma cruzi cysteine peptidase, putative 0.0253 0.206 0.203
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0178 0.1427 0.1502
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0063 0.0453 0.0453
Onchocerca volvulus 0.0009 0 0.0002
Schistosoma mansoni cyclins 0.0055 0.0391 0.0391
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0253 0.206 0.2187
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Echinococcus granulosus 7TM GPCR rhodopsin 0.0009 0.0004 0.0004
Schistosoma mansoni adapter molecule crk 0.0014 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Brugia malayi Cation transporter family protein 0.0082 0.0618 0.0618
Leishmania major cathepsin L-like protease 0.0253 0.206 0.2187
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0253 0.206 0.2187
Giardia lamblia Cathepsin B precursor 0.0127 0.0995 0.1035
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0127 0.0995 0.1035
Giardia lamblia Cathepsin L-like protease 0.0127 0.0995 0.1035
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0051 0.0357 0.0357
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0082 0.0618 0.0618
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0127 0.0995 0.4735
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0009 0.0004 0.0018
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0127 0.0995 0.4735
Plasmodium vivax vivapain-2 0.0253 0.206 1
Giardia lamblia Cathepsin B precursor 0.0127 0.0995 0.1035
Loa Loa (eye worm) latrophilin receptor protein 2 0.0014 0.0042 0.0042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0241 0.0241
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0202 0.1628 0.172
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.1193 1 1
Echinococcus multilocularis neuropeptide receptor A26 0.0383 0.3161 0.3161
Brugia malayi Cyclin, N-terminal domain containing protein 0.0013 0.0038 0.0038
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0127 0.0995 0.4735
Schistosoma mansoni hypothetical protein 0.0029 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0202 0.1628 0.1628
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0069 0.051 0.051
Onchocerca volvulus 0.0009 0 0.0002
Entamoeba histolytica cyclin, domain containing protein 0.0013 0.0038 0.0182
Toxoplasma gondii preprocathepsin c precursor, putative 0.0127 0.0995 0.1035
Entamoeba histolytica cysteine protease, putative 0.0127 0.0995 0.4831
Onchocerca volvulus 0.0009 0 0.0002
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Onchocerca volvulus 0.0038 0.0245 0.1189
Loa Loa (eye worm) hypothetical protein 0.0055 0.0391 0.0391
Echinococcus granulosus hypothetical protein 0.0009 0.0004 0.0004
Brugia malayi Variant SH3 domain containing protein 0.0014 0.0041 0.0041
Echinococcus multilocularis NCK adaptor protein 0.0014 0.0041 0.0041
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis tyrosine protein kinase Abl 0.0016 0.0057 0.0057
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0009 0.0004 0.0004
Plasmodium vivax unspecified product 0.0178 0.1427 0.687
Leishmania major cathepsin L-like protease 0.0253 0.206 0.2187
Mycobacterium ulcerans hydantoin racemase 0.0329 0.2705 0.3702
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Echinococcus multilocularis serotonin receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Brugia malayi Cathepsin L-like cysteine proteinase 0.0202 0.1628 0.1628
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0037 0.0241 0.0241
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0241 0.0241
Brugia malayi Cathepsin L-like precursor 0.0253 0.206 0.206
Onchocerca volvulus 0.0082 0.0618 0.3001
Brugia malayi hypothetical protein 0.0038 0.0245 0.0245
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Schistosoma mansoni adenoreceptor 0.0009 0.0004 0.0004
Brugia malayi RNA binding protein 0.0055 0.0393 0.0393
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Schistosoma mansoni cathepsin s 0.0051 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0029 0.0174 0.0842
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0069 0.051 0.051
Echinococcus multilocularis neuropeptides capa receptor 0.0009 0.0004 0.0004
Echinococcus granulosus cyclin t1 0.0013 0.0038 0.0038
Echinococcus granulosus c src tyrosine kinase 0.0016 0.0057 0.0057
Trichomonas vaginalis cyclin B, putative 0.0055 0.0391 0.0382
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0253 0.206 0.206
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.1109 0.9285 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0127 0.0995 0.0995
Echinococcus granulosus serotonin receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus granulosus inositol monophosphatase 1 0.003 0.018 0.018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0024 0.0131 0.0131
Entamoeba histolytica cysteine proteinase 1, putative 0.0178 0.1427 0.6927
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Echinococcus granulosus neuropeptide Y receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0202 0.1628 0.1628
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis g protein coupled receptor 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0253 0.206 0.2187
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0063 0.0453 0.0453
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0014 0.0042 0.0042
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Onchocerca volvulus 0.0082 0.0618 0.3001
Echinococcus granulosus dro:myosuppressin receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0009 0.0004 0.0004
Brugia malayi hypothetical protein 0.0009 0.0004 0.0004
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0037 0.0241 0.0241
Schistosoma mansoni hypothetical protein 0.0014 0.0042 0.0042
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0127 0.0995 0.0995
Schistosoma mansoni alpha-1 adrenergic receptor 0.0009 0.0004 0.0004
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0044 0.0299 0.0299
Schistosoma mansoni hypothetical protein 0.0013 0.0038 0.0038
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0253 0.206 0.206
Echinococcus granulosus cyclin 0.0013 0.0038 0.0038
Giardia lamblia Cathepsin L precursor 0.0127 0.0995 0.1035
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0253 0.206 0.2187
Onchocerca volvulus 0.0009 0.0004 0.0018
Echinococcus granulosus cyclin B3 1 0.0055 0.0391 0.0391
Loa Loa (eye worm) hypothetical protein 0.0127 0.0995 0.0995
Loa Loa (eye worm) cyclin domain-containing protein 0.0013 0.0038 0.0038
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0069 0.051 0.051
Onchocerca volvulus 0.0253 0.206 1
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0127 0.0995 0.1035
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0014 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0009 0.0004 0.0004
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0009 0.0004 0.0004
Echinococcus multilocularis neuropeptide Y receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0253 0.206 1
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0082 0.0618 0.0618
Loa Loa (eye worm) TK protein kinase 0.0056 0.0395 0.0395
Loa Loa (eye worm) cyclin fold protein 1 variant b 0.0013 0.0038 0.0038
Entamoeba histolytica cyclin family protein 0.0055 0.0391 0.1897
Schistosoma mansoni amine GPCR 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0253 0.206 0.2187
Echinococcus granulosus 7tm_1 domain containing protein 0.0009 0.0004 0.0004
Schistosoma mansoni amine GPCR 0.0009 0.0004 0.0004
Toxoplasma gondii hypothetical protein 0.0042 0.0279 0.026
Brugia malayi SRC-1 0.0069 0.051 0.051
Echinococcus granulosus g protein coupled receptor 0.0009 0.0004 0.0004
Brugia malayi Papain family cysteine protease containing protein 0.0127 0.0995 0.0995
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0069 0.051 0.051
Leishmania major cathepsin L-like protease 0.0253 0.206 0.2187
Trichomonas vaginalis cyclins, putative 0.0055 0.0391 0.0382
Schistosoma mansoni tar DNA-binding protein 0.0055 0.0393 0.0393
Brugia malayi hypothetical protein 0.0038 0.0245 0.0245
Echinococcus granulosus geminin 0.0424 0.3507 0.3507
Entamoeba histolytica cyclin, putative 0.0055 0.0391 0.1897
Loa Loa (eye worm) hypothetical protein 0.0014 0.0041 0.0041
Brugia malayi Papain family cysteine protease containing protein 0.0127 0.0995 0.0995
Brugia malayi Papain family cysteine protease containing protein 0.0178 0.1427 0.1427
Onchocerca volvulus Cathepsin L homolog 0.0253 0.206 1
Loa Loa (eye worm) RNA binding protein 0.0055 0.0393 0.0393
Echinococcus multilocularis cathepsin b 0.1193 1 1
Loa Loa (eye worm) TYRA-2 protein 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0044 0.0299 0.0299
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0082 0.0618 0.0618
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0127 0.0995 0.0995
Echinococcus granulosus neuropeptides capa receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0009 0.0004 0.0004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0037 0.0241 0.0241
Echinococcus multilocularis oligomeric golgi complex subunit 3 0.0013 0.0038 0.0038
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0044 0.0293 0.0293
Giardia lamblia Cysteine protease 0.0127 0.0995 0.1035
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0009 0.0004 0.0004
Giardia lamblia Cathepsin L precursor 0.0127 0.0995 0.1035
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0127 0.0995 0.4735
Echinococcus granulosus fmrfamide receptor 0.0009 0.0004 0.0004
Brugia malayi hypothetical protein 0.0207 0.1669 0.1669
Echinococcus granulosus g protein coupled receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Entamoeba histolytica cysteine proteinase, putative 0.0178 0.1427 0.6927
Brugia malayi Variant SH3 domain containing protein 0.0014 0.0041 0.0041
Schistosoma mansoni hypothetical protein 0.003 0.0177 0.0177
Onchocerca volvulus Neuropeptide F receptor homolog 0.0009 0.0004 0.0018
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0055 0.0391 0.0382
Echinococcus granulosus NCK adaptor protein 0.0014 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0051 0.0357 0.0357
Onchocerca volvulus 0.0009 0.0004 0.0018
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0029 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.0127 0.0995 0.0995
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0082 0.0618 0.0618
Echinococcus multilocularis nAChR subunit 0.0082 0.0618 0.0618
Schistosoma mansoni hypothetical protein 0.0014 0.0042 0.0042
Onchocerca volvulus 0.0038 0.0245 0.1189
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1193 1 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0253 0.206 0.206
Loa Loa (eye worm) hypothetical protein 0.0013 0.0038 0.0038
Trypanosoma cruzi cruzipain precursor, putative 0.0051 0.0357 0.032
Onchocerca volvulus 0.0024 0.0131 0.0638
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0127 0.0995 0.0995
Echinococcus granulosus biogenic amine 5HT receptor 0.0009 0.0004 0.0004
Brugia malayi protein-tyrosine kinase 0.0063 0.0453 0.0453
Giardia lamblia Hypothetical protein 0.0127 0.0995 0.1035
Echinococcus granulosus alpha 1A adrenergic receptor 0.0009 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0014 0.0042 0.0042
Entamoeba histolytica cysteine protease, putative 0.0178 0.1427 0.6927
Entamoeba histolytica cysteine proteinase, putative 0.0202 0.1628 0.7905
Plasmodium falciparum serine repeat antigen 8 0.0127 0.0995 0.4735
Schistosoma mansoni cathepsin F (C01 family) 0.0253 0.206 0.206
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0044 0.0299 0.0299
Schistosoma mansoni growth hormone secretagogue receptor 0.0009 0.0004 0.0004
Echinococcus multilocularis cathepsin L 0.0178 0.1427 0.1427
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0127 0.0995 0.4735
Entamoeba histolytica cysteine proteinase, putative 0.0178 0.1427 0.6927
Loa Loa (eye worm) hypothetical protein 0.0044 0.0299 0.0299
Giardia lamblia Cathepsin B precursor 0.0127 0.0995 0.1035
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0009 0.0004 0.0004
Echinococcus granulosus g protein coupled receptor 0.0009 0.0004 0.0004
Echinococcus granulosus biogenic amine 5HT receptor 0.0009 0.0004 0.0004
Echinococcus granulosus g-protein coupled receptor 0.0009 0.0004 0.0004
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0037 0.0241 0.0241
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0038 0.0245 0.0245
Echinococcus granulosus glycine receptor subunit beta 0.0082 0.0618 0.0618
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0082 0.0618 0.0618
Schistosoma mansoni nAChR subunit 0.0082 0.0618 0.0618
Plasmodium falciparum serine repeat antigen 2 0.0127 0.0995 0.4735
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0069 0.051 0.051
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0009 0.0004 0.0004
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0127 0.0995 0.0995
Echinococcus multilocularis sex peptide receptor 0.0009 0.0004 0.0004
Entamoeba histolytica hypothetical protein 0.0013 0.0038 0.0182
Brugia malayi hypothetical protein 0.0009 0.0004 0.0004
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0038 0.0245 0.0245
Schistosoma mansoni neuropeptide f receptor 76f 0.0009 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Brugia malayi Cyclin, N-terminal domain containing protein 0.0013 0.0038 0.0038
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Brugia malayi hypothetical protein 0.0009 0.0004 0.0004
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0253 0.206 0.2187
Trypanosoma cruzi cyclin, putative 0.0055 0.0391 0.0355
Loa Loa (eye worm) hypothetical protein 0.0038 0.0245 0.0245
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0014 0.0042 0.0042
Echinococcus granulosus tyrosine protein kinase Blk 0.0063 0.0453 0.0453
Onchocerca volvulus 0.0009 0.0004 0.0018
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.003 0.018 0.0143
Brugia malayi neuropeptide F receptor 0.0009 0.0004 0.0004
Mycobacterium leprae PROBABLE GLUTAMATE RACEMASE MURI 0.0838 0.7 1
Loa Loa (eye worm) hypothetical protein 0.0082 0.0618 0.0618
Giardia lamblia Cyclin A 0.0055 0.0391 0.0382
Schistosoma mansoni cathepsin C 0.0127 0.0995 0.0995
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0082 0.0618 0.0618
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0082 0.0618 0.0618
Brugia malayi Cyclin, N-terminal domain containing protein 0.0013 0.0038 0.0038
Echinococcus multilocularis cyclins 0.0055 0.0391 0.0391
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0127 0.0995 0.1035
Onchocerca volvulus 0.0009 0.0004 0.0018
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0178 0.1427 0.1427
Schistosoma mansoni nAChR subunit 0.0082 0.0618 0.0618
Trypanosoma brucei cysteine peptidase C (CPC) 0.1109 0.9285 1
Trichomonas vaginalis cyclin B, putative 0.0055 0.0391 0.0382
Leishmania major cysteine peptidase A (CPA) 0.0253 0.206 0.2187
Loa Loa (eye worm) hypothetical protein 0.0044 0.0299 0.0299
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0082 0.0618 0.0618
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Plasmodium falciparum cysteine proteinase falcipain 3 0.0253 0.206 1
Onchocerca volvulus 0.0009 0.0004 0.0018
Trichomonas vaginalis cyclin D, putative 0.0055 0.0391 0.0382
Loa Loa (eye worm) hypothetical protein 0.0009 0.0004 0.0004
Brugia malayi Calcitonin receptor-like protein seb-1 0.0044 0.0293 0.0293
Giardia lamblia Cathepsin L precursor 0.0127 0.0995 0.1035
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0082 0.0618 0.0618
Onchocerca volvulus Huntingtin homolog 0.0139 0.11 0.5341
Echinococcus multilocularis cyclin B3 1 0.0055 0.0391 0.0391
Echinococcus granulosus cathepsin b 0.1193 1 1
Echinococcus multilocularis glycine receptor subunit beta 0.0082 0.0618 0.0618
Echinococcus multilocularis cathepsin b 0.1193 1 1
Plasmodium falciparum serine repeat antigen 1 0.0127 0.0995 0.4735
Brugia malayi TAR-binding protein 0.0055 0.0393 0.0393
Giardia lamblia Cathepsin L precursor 0.0127 0.0995 0.1035
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0082 0.0618 0.0618
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0082 0.0618 0.0618
Echinococcus granulosus neuropeptide s receptor 0.0383 0.3161 0.3161
Schistosoma mansoni opsin-like receptor 0.0009 0.0004 0.0004

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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