Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cathepsin L-like precursor | 0.0503 | 0.1158 | 0.1158 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0503 | 0.1158 | 0.1158 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2136 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0503 | 0.1158 | 0.1158 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0503 | 0.1158 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Loa Loa (eye worm) | cathepsin B | 0.0759 | 0.2547 | 0.2262 |
Onchocerca volvulus | 0.0503 | 0.1158 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Echinococcus multilocularis | cathepsin b | 0.2136 | 1 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0503 | 0.1158 | 0.1158 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0503 | 0.1158 | 0.1158 |
Brugia malayi | Cathepsin L-like precursor | 0.0503 | 0.1158 | 0.1158 |
Echinococcus granulosus | cathepsin l1 | 0.0357 | 0.0368 | 0.0368 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0759 | 0.2547 | 0.2547 |
Plasmodium vivax | vivapain-2 | 0.0503 | 0.1158 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.2136 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Loa Loa (eye worm) | hypothetical protein | 0.2136 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Onchocerca volvulus | 0.0503 | 0.1158 | 1 | |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0503 | 0.1158 | 0.082 |
Loa Loa (eye worm) | fibroinase | 0.0503 | 0.1158 | 0.082 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Onchocerca volvulus | 0.0503 | 0.1158 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Toxoplasma gondii | cathepsin B | 0.0759 | 0.2547 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0759 | 0.2547 | 1 |
Onchocerca volvulus | 0.0503 | 0.1158 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Loa Loa (eye worm) | ctsf protein | 0.0503 | 0.1158 | 0.082 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0357 | 0.0368 | 0.0368 |
Brugia malayi | Cathepsin L-like precursor | 0.0503 | 0.1158 | 0.1158 |
Brugia malayi | Cathepsin L-like precursor | 0.0503 | 0.1158 | 0.1158 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0503 | 0.1158 | 0.1158 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2136 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.2136 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0759 | 0.2547 | 0.2547 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0357 | 0.0368 | 0.3182 |
Onchocerca volvulus | Cathepsin L homolog | 0.0503 | 0.1158 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0759 | 0.2547 | 1 |
Onchocerca volvulus | 0.0503 | 0.1158 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Brugia malayi | Cathepsin L-like precursor | 0.0357 | 0.0368 | 0.0368 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0503 | 0.1158 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0503 | 0.1158 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0759 | 0.2547 | 0.5 |
Giardia lamblia | Cathepsin B precursor | 0.0759 | 0.2547 | 0.5 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0357 | 0.0368 | 0.0368 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0503 | 0.1158 | 0.1158 |
Plasmodium vivax | vivapain-2 | 0.0503 | 0.1158 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0503 | 0.1158 | 0.1158 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0503 | 0.1158 | 0.1158 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0503 | 0.1158 | 0.1158 |
Onchocerca volvulus | 0.0503 | 0.1158 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0357 | 0.0368 | 0.1446 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0503 | 0.1158 | 0.1158 |
Brugia malayi | Cathepsin L-like precursor | 0.0503 | 0.1158 | 0.1158 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0357 | 0.0368 | 0.1446 |
Echinococcus granulosus | cathepsin b | 0.2136 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0503 | 0.1158 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Giardia lamblia | Cathepsin B precursor | 0.0759 | 0.2547 | 0.5 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0503 | 0.1158 | 0.1158 |
Entamoeba histolytica | cysteine protease, putative | 0.0503 | 0.1158 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0503 | 0.1158 | 0.1158 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0503 | 0.1158 | 0.082 |
Brugia malayi | cathepsin L-like precursor | 0.0357 | 0.0368 | 0.0368 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0503 | 0.1158 | 0.1158 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0503 | 0.1158 | 0.1158 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0503 | 0.1158 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0503 | 0.1158 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0503 | 0.1158 | 0.082 |
Brugia malayi | Cathepsin L-like precursor | 0.0503 | 0.1158 | 0.1158 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Brugia malayi | Cathepsin L-like precursor | 0.0357 | 0.0368 | 0.0368 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Loa Loa (eye worm) | cysteine protease | 0.0503 | 0.1158 | 0.082 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0759 | 0.2547 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0503 | 0.1158 | 0.4546 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0357 | 0.0368 | 0.0368 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Echinococcus multilocularis | cysteine protease | 0.0503 | 0.1158 | 0.1158 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.2136 | 1 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0503 | 0.1158 | 0.1158 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0503 | 0.1158 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0503 | 0.1158 | 0.4546 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0503 | 0.1158 | 0.1158 |
Echinococcus multilocularis | cathepsin b | 0.2136 | 1 | 1 |
Onchocerca volvulus | 0.0503 | 0.1158 | 1 | |
Echinococcus granulosus | cathepsin b | 0.2136 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.