Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | ring and YY1 binding protein | 0.008 | 0.3346 | 0.3346 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3346 | 0.3346 |
Echinococcus multilocularis | tar DNA binding protein | 0.0051 | 0.2012 | 0.2012 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.008 | 0.3346 | 0.3346 |
Loa Loa (eye worm) | brahma associated protein | 0.0225 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0225 | 1 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0051 | 0.2012 | 0.2012 |
Schistosoma mansoni | hypothetical protein | 0.0225 | 1 | 1 |
Onchocerca volvulus | 0.0225 | 1 | 1 | |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.008 | 0.3346 | 0.3346 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.008 | 0.3346 | 0.3346 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.008 | 0.3346 | 0.5 |
Onchocerca volvulus | 0.008 | 0.3346 | 0.3346 | |
Trypanosoma cruzi | hypothetical protein, conserved | 0.008 | 0.3346 | 0.5 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.008 | 0.3346 | 0.3346 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.6342 | 0.6342 |
Brugia malayi | N-terminal motif family protein | 0.0145 | 0.6342 | 0.6342 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.008 | 0.3346 | 0.5 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.008 | 0.3346 | 0.3346 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.008 | 0.3346 | 0.3346 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.008 | 0.3346 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.008 | 0.3346 | 0.5 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0225 | 1 | 1 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.008 | 0.3346 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.008 | 0.3346 | 0.3346 |
Schistosoma mansoni | tar DNA-binding protein | 0.0051 | 0.2012 | 0.2012 |
Schistosoma mansoni | hypothetical protein | 0.0136 | 0.5933 | 0.5933 |
Trypanosoma brucei | hypothetical protein, conserved | 0.008 | 0.3346 | 0.5 |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.008 | 0.3346 | 0.3346 |
Leishmania major | hypothetical protein, conserved | 0.008 | 0.3346 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.008 | 0.3346 | 0.5 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.008 | 0.3346 | 0.3346 |
Loa Loa (eye worm) | RNA binding protein | 0.0051 | 0.2012 | 0.2012 |
Onchocerca volvulus | 0.008 | 0.3346 | 0.3346 | |
Chlamydia trachomatis | SWIB complex protein | 0.0225 | 1 | 0.5 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.008 | 0.3346 | 0.5 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.008 | 0.3346 | 0.5 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.008 | 0.3346 | 0.5 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0225 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.008 | 0.3346 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0225 | 1 | 1 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.008 | 0.3346 | 0.3346 |
Schistosoma mansoni | tar DNA-binding protein | 0.0051 | 0.2012 | 0.2012 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.008 | 0.3346 | 0.3346 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0225 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.008 | 0.3346 | 0.3346 |
Schistosoma mansoni | hypothetical protein | 0.0225 | 1 | 1 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.008 | 0.3346 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.008 | 0.3346 | 0.5 |
Schistosoma mansoni | brg-1 associated factor | 0.0225 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.008 | 0.3346 | 0.5 |
Echinococcus multilocularis | geminin | 0.0136 | 0.5933 | 0.5933 |
Schistosoma mansoni | tar DNA-binding protein | 0.0051 | 0.2012 | 0.2012 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0225 | 1 | 1 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.008 | 0.3346 | 0.5 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0225 | 1 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0225 | 1 | 0.5 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0225 | 1 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0051 | 0.2012 | 0.2012 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0225 | 1 | 1 |
Schistosoma mansoni | RNA binding protein | 0.008 | 0.3346 | 0.3346 |
Onchocerca volvulus | 0.008 | 0.3346 | 0.3346 | |
Brugia malayi | RNA recognition motif domain containing protein | 0.0051 | 0.2012 | 0.2012 |
Echinococcus granulosus | ring and YY1 binding protein | 0.008 | 0.3346 | 0.3346 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.008 | 0.3346 | 0.3346 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.008 | 0.3346 | 0.3346 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0145 | 0.6342 | 0.6342 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0225 | 1 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.008 | 0.3346 | 0.3346 |
Loa Loa (eye worm) | TAR-binding protein | 0.0051 | 0.2012 | 0.2012 |
Brugia malayi | TAR-binding protein | 0.0051 | 0.2012 | 0.2012 |
Brugia malayi | YY1-associated factor 2 | 0.008 | 0.3346 | 0.3346 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0225 | 1 | 1 |
Brugia malayi | RNA binding protein | 0.0051 | 0.2012 | 0.2012 |
Brugia malayi | brahma associated protein 60 kDa | 0.0225 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0136 | 0.5933 | 0.5933 |
Onchocerca volvulus | 0.008 | 0.3346 | 0.3346 | |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0225 | 1 | 1 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0225 | 1 | 0.5 |
Schistosoma mansoni | fusion | 0.008 | 0.3346 | 0.3346 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3346 | 0.3346 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3346 | 0.3346 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0225 | 1 | 1 |
Toxoplasma gondii | ran binding protein | 0.008 | 0.3346 | 0.3346 |
Leishmania major | hypothetical protein, conserved | 0.008 | 0.3346 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3346 | 0.3346 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0225 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.008 | 0.3346 | 0.3346 |
Echinococcus granulosus | geminin | 0.0136 | 0.5933 | 0.5933 |
Schistosoma mansoni | tar DNA-binding protein | 0.0051 | 0.2012 | 0.2012 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.008 | 0.3346 | 0.5 |
Echinococcus granulosus | tar DNA binding protein | 0.0051 | 0.2012 | 0.2012 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0225 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.