Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0025 | 0.0041 | 0.0079 |
Schistosoma mansoni | hypothetical protein | 0.0072 | 0.0309 | 0.0803 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.0916 | 0.2433 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.0113 | 0.0543 | 0.0738 |
Trichomonas vaginalis | esterase, putative | 0.0113 | 0.0543 | 1 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.0074 | 0.0065 |
Onchocerca volvulus | 0.0113 | 0.0543 | 0.6857 | |
Trichomonas vaginalis | CMGC family protein kinase | 0.0106 | 0.0503 | 0.9236 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0106 | 0.0503 | 0.0494 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.0732 | 0.194 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.0732 | 0.0724 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0055 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0055 | 0.0112 |
Giardia lamblia | Kinase, PLK | 0.0111 | 0.0534 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.0074 | 0.0159 |
Brugia malayi | jmjC domain containing protein | 0.0037 | 0.0111 | 0.0269 |
Plasmodium vivax | hypothetical protein, conserved | 0.0113 | 0.0543 | 1 |
Onchocerca volvulus | 0.0151 | 0.0758 | 1 | |
Mycobacterium tuberculosis | Probable lipase LipE | 0.0113 | 0.0543 | 0.0738 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0025 | 0.0041 | 0.0605 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0025 | 0.0041 | 0.0605 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.0113 | 0.0543 | 0.0738 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0106 | 0.0503 | 0.9236 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.01 | 0.047 | 0.0462 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0106 | 0.0503 | 0.1204 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0113 | 0.0543 | 0.1303 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0056 | 0.0874 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0309 | 0.5702 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0074 | 0.018 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0055 | 0.086 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.01 | 0.0471 | 0.1145 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0106 | 0.0503 | 0.9236 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0113 | 0.0543 | 0.1322 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0106 | 0.0503 | 0.1204 |
Echinococcus granulosus | expressed conserved protein | 0.0094 | 0.0436 | 0.1042 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0309 | 0.5702 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.02 | 0.0466 |
Leishmania major | GTP-binding protein, putative | 0.0025 | 0.0041 | 0.0605 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0106 | 0.0503 | 0.1323 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.01 | 0.0471 | 0.1126 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0219 | 0.029 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0041 | 0.0615 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0106 | 0.0503 | 0.9236 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0055 | 0.5534 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0739 | 0.4109 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0113 | 0.0543 | 1 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0106 | 0.0503 | 0.9236 |
Brugia malayi | hypothetical protein | 0.0739 | 0.4109 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Giardia lamblia | PHD finger protein 15 | 0.0031 | 0.0074 | 0.1239 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0111 | 0.0534 | 0.0526 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Schistosoma mansoni | importin beta-1 | 0.0034 | 0.0092 | 0.0223 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0034 | 0.0092 | 0.1554 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0146 | 0.0732 | 0.1783 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0219 | 0.021 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0072 | 0.0309 | 0.03 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0113 | 0.0543 | 0.1433 |
Mycobacterium tuberculosis | Arylamine N-acetyltransferase Nat (arylamine acetylase) | 0.129 | 0.7246 | 1 |
Leishmania major | importin beta-1 subunit, putative | 0.0027 | 0.0056 | 0.0874 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0145 | 0.0331 |
Entamoeba histolytica | Ran family GTPase | 0.0025 | 0.0041 | 0.0615 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0111 | 0.0534 | 0.1409 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0136 | 0.0341 |
Echinococcus multilocularis | expressed conserved protein | 0.0094 | 0.0436 | 0.0427 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.0009 | 0.5 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.01 | 0.0471 | 0.8785 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0674 | 0.3738 | 0.3732 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0111 | 0.0273 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.01 | 0.0471 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0198 | 0.0462 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0043 | 0.0145 | 0.0331 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0111 | 0.0534 | 0.9834 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.0113 | 0.0543 | 0.0738 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0106 | 0.0503 | 0.0494 |
Brugia malayi | MAP kinase sur-1 | 0.0106 | 0.0503 | 0.1223 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0111 | 0.0534 | 0.1282 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.0471 | 0.1126 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0113 | 0.0543 | 1 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0025 | 0.0041 | 0.0605 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0052 | 0.0198 | 0.046 |
Leishmania major | hypothetical protein, conserved | 0.0113 | 0.0543 | 1 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0102 | 0.0479 | 0.1262 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0043 | 0.0145 | 0.0331 |
Schistosoma mansoni | hypothetical protein | 0.0179 | 0.0916 | 0.2433 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0146 | 0.0732 | 0.0724 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.0074 | 0.0065 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0009 | 0.0022 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0055 | 0.086 |
Brugia malayi | MH2 domain containing protein | 0.0117 | 0.0564 | 0.1373 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0074 | 0.0175 |
Plasmodium vivax | importin-beta 2, putative | 0.0034 | 0.0092 | 0.1554 |
Trypanosoma brucei | protein kinase, putative | 0.0106 | 0.0503 | 0.9236 |
Echinococcus multilocularis | snurportin 1 | 0.036 | 0.195 | 0.1943 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0106 | 0.0503 | 0.9236 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0056 | 0.0219 | 0.0533 |
Trypanosoma brucei | polo-like protein kinase | 0.0111 | 0.0534 | 0.9834 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0041 | 0.0079 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0674 | 0.3738 | 0.9096 |
Schistosoma mansoni | hypothetical protein | 0.0151 | 0.0758 | 0.201 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.0113 | 0.0543 | 0.0738 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0136 | 0.0341 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0041 | 0.0101 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0106 | 0.0503 | 0.9392 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0037 | 0.0111 | 0.0248 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0037 | 0.0111 | 0.0248 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.036 | 0.195 | 0.4734 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0.0074 | 0.7841 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.0113 | 0.0543 | 0.0738 |
Mycobacterium ulcerans | lipase LipD | 0.0113 | 0.0543 | 0.0738 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0056 | 0.0219 | 0.0563 |
Mycobacterium leprae | conserved hypothetical protein | 0.0113 | 0.0543 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0309 | 0.5702 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0739 | 0.4109 | 0.4103 |
Mycobacterium tuberculosis | Conserved protein | 0.0113 | 0.0543 | 0.0738 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0106 | 0.0503 | 0.9236 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0055 | 0.086 |
Mycobacterium tuberculosis | Conserved protein | 0.0113 | 0.0543 | 0.0738 |
Plasmodium falciparum | importin beta, putative | 0.0034 | 0.0092 | 1 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0027 | 0.0056 | 0.0874 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0034 | 0.0092 | 0.0083 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0074 | 0.1218 |
Brugia malayi | beta-lactamase family protein | 0.0113 | 0.0543 | 0.1322 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0056 | 0.0219 | 0.0512 |
Schistosoma mansoni | patched 1 | 0.0043 | 0.0145 | 0.0364 |
Echinococcus granulosus | snurportin 1 | 0.036 | 0.195 | 0.4734 |
Entamoeba histolytica | hypothetical protein | 0.0072 | 0.0309 | 0.5702 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0106 | 0.0503 | 0.9236 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.0732 | 0.1765 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Loa Loa (eye worm) | beta-lactamase | 0.0113 | 0.0543 | 0.1303 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0111 | 0.0534 | 0.1301 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0106 | 0.0503 | 0.9236 |
Onchocerca volvulus | 0.0113 | 0.0543 | 0.6857 | |
Mycobacterium ulcerans | hypothetical protein | 0.0113 | 0.0543 | 0.0738 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0117 | 0.0564 | 0.1354 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.0074 | 0.018 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0113 | 0.0543 | 0.0535 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0111 | 0.0102 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 0.0543 | 1 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0113 | 0.0543 | 1 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0027 | 0.0056 | 0.0874 |
Echinococcus granulosus | geminin | 0.0179 | 0.0916 | 0.2213 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.0009 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0113 | 0.0543 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0074 | 0.1218 |
Schistosoma mansoni | hypothetical protein | 0.036 | 0.195 | 0.5205 |
Mycobacterium leprae | Probable lipase LipE | 0.0113 | 0.0543 | 0.5 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0113 | 0.0543 | 0.1433 |
Brugia malayi | jmjC domain containing protein | 0.01 | 0.047 | 0.1144 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0055 | 0.086 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0074 | 0.0159 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0113 | 0.0543 | 1 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0034 | 0.0092 | 0.1554 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0111 | 0.0534 | 0.9834 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.0074 | 0.0175 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0025 | 0.0041 | 0.0605 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0043 | 0.0145 | 0.0136 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0111 | 0.0534 | 0.9834 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0056 | 0.0217 | 0.3889 |
Mycobacterium tuberculosis | Probable hydrolase | 0.0113 | 0.0543 | 0.0738 |
Schistosoma mansoni | ran | 0.0025 | 0.0041 | 0.0087 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.0732 | 0.194 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0043 | 0.0142 | 0.0133 |
Schistosoma mansoni | survival motor neuron protein | 0.0151 | 0.0758 | 0.201 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.0113 | 0.0543 | 0.0738 |
Entamoeba histolytica | hypothetical protein | 0.0027 | 0.0056 | 0.0889 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0136 | 0.0341 |
Echinococcus multilocularis | protein dispatched 1 | 0.0049 | 0.0179 | 0.0171 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0113 | 0.0543 | 0.1303 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0722 | 0.401 | 0.5529 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0143 | 0.0715 | 0.0707 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0043 | 0.0145 | 0.2543 |
Brugia malayi | RNA, U transporter 1 | 0.0096 | 0.0446 | 0.1086 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0106 | 0.0503 | 0.9236 |
Echinococcus granulosus | jumonji domain containing protein | 0.0043 | 0.0142 | 0.0325 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0111 | 0.0534 | 0.6727 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.0113 | 0.0543 | 0.0738 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0106 | 0.0503 | 0.1204 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0309 | 0.0751 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0106 | 0.0503 | 0.9236 |
Toxoplasma gondii | ABC1 family protein | 0.0113 | 0.0543 | 1 |
Brugia malayi | CHE-14 protein | 0.0043 | 0.0145 | 0.0353 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Echinococcus multilocularis | protein patched | 0.0043 | 0.0145 | 0.0136 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0092 | 0.0203 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0106 | 0.0503 | 0.9236 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0113 | 0.0543 | 1 |
Trichomonas vaginalis | ran, putative | 0.0025 | 0.0041 | 0.0605 |
Echinococcus multilocularis | geminin | 0.0179 | 0.0916 | 0.0908 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0674 | 0.3738 | 1 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0043 | 0.0145 | 0.0331 |
Loa Loa (eye worm) | hypothetical protein | 0.0739 | 0.4109 | 1 |
Schistosoma mansoni | kinase | 0.0057 | 0.0225 | 0.058 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0113 | 0.0543 | 1 |
Trichomonas vaginalis | importin beta-1, putative | 0.0027 | 0.0056 | 0.0874 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0146 | 0.0732 | 0.1765 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0055 | 0.5534 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0025 | 0.0041 | 0.0032 |
Brugia malayi | Importin beta-1 subunit | 0.0034 | 0.0092 | 0.0224 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0056 | 0.0219 | 0.029 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0056 | 0.0217 | 0.3889 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.0543 | 0.1303 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.0074 | 0.0159 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0146 | 0.0732 | 0.1765 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0034 | 0.0092 | 0.1554 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0151 | 0.0758 | 0.1846 |
Echinococcus granulosus | importin subunit beta 1 | 0.0034 | 0.0092 | 0.0203 |
Brugia malayi | beta-lactamase | 0.0113 | 0.0543 | 0.1322 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0037 | 0.0111 | 0.0273 |
Onchocerca volvulus | 0.0113 | 0.0543 | 0.6857 | |
Mycobacterium tuberculosis | Conserved protein | 0.0113 | 0.0543 | 0.0738 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0056 | 0.0219 | 0.3931 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.01 | 0.047 | 0.1125 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0111 | 0.0534 | 0.9834 |
Schistosoma mansoni | jumonji domain containing protein | 0.008 | 0.0353 | 0.0922 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0055 | 0.086 |
Mycobacterium ulcerans | beta-lactamase | 0.0113 | 0.0543 | 0.0738 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0111 | 0.0534 | 1 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0056 | 0.0219 | 0.029 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0025 | 0.0041 | 0.0605 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0074 | 0.1218 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0072 | 0.0309 | 0.0731 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0146 | 0.0732 | 0.194 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0055 | 0.086 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0111 | 0.0534 | 0.1282 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0143 | 0.0715 | 0.1723 |
Brugia malayi | beta-lactamase family protein | 0.0113 | 0.0543 | 0.1322 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0072 | 0.0309 | 0.0803 |
Echinococcus granulosus | peregrin | 0.0031 | 0.0074 | 0.0159 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0117 | 0.0564 | 0.1354 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0136 | 0.0341 |
Mycobacterium ulcerans | arylamine N-acetyltransferase Nat | 0.129 | 0.7246 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.0259 | 0.0611 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0025 | 0.0041 | 0.3893 |
Schistosoma mansoni | ran | 0.0025 | 0.0041 | 0.0087 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.