Detailed information for compound 1897966

Basic information

Technical information
  • TDR Targets ID: 1897966
  • Name: 1-[(2S)-2,3-dihydroxypropyl]pyrimidine-2,4-di one
  • MW: 186.165 | Formula: C7H10N2O4
  • H donors: 3 H acceptors: 4 LogP: -2.09 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: O[C@H](CO)Cn1ccc(=O)[nH]c1=O
  • InChi: 1S/C7H10N2O4/c10-4-5(11)3-9-2-1-6(12)8-7(9)13/h1-2,5,10-11H,3-4H2,(H,8,12,13)/t5-/m0/s1
  • InChiKey: UPONUIQDSKBZHK-YFKPBYRVSA-N  

Network

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Synonyms

  • AIDS351773
  • ZINC01439775
  • (S)-1-(2,3-Dihydroxypropyl)uracil
  • AIDS-351773

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus GTP binding nuclear protein Ran 0.0025 0.0041 0.0079
Schistosoma mansoni hypothetical protein 0.0072 0.0309 0.0803
Schistosoma mansoni hypothetical protein 0.0179 0.0916 0.2433
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0113 0.0543 0.0738
Trichomonas vaginalis esterase, putative 0.0113 0.0543 1
Echinococcus multilocularis peregrin 0.0031 0.0074 0.0065
Onchocerca volvulus 0.0113 0.0543 0.6857
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0503 0.9236
Loa Loa (eye worm) hypothetical protein 0.0113 0.0543 0.1303
Echinococcus multilocularis mitogen activated protein kinase 3 0.0106 0.0503 0.0494
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0732 0.194
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.0732 0.0724
Loa Loa (eye worm) hypothetical protein 0.0113 0.0543 0.1303
Brugia malayi hypothetical protein 0.0027 0.0055 0.0134
Loa Loa (eye worm) hypothetical protein 0.0027 0.0055 0.0112
Giardia lamblia Kinase, PLK 0.0111 0.0534 1
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0074 0.0159
Brugia malayi jmjC domain containing protein 0.0037 0.0111 0.0269
Plasmodium vivax hypothetical protein, conserved 0.0113 0.0543 1
Onchocerca volvulus 0.0151 0.0758 1
Mycobacterium tuberculosis Probable lipase LipE 0.0113 0.0543 0.0738
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0041 0.0605
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0025 0.0041 0.0605
Mycobacterium ulcerans esterase/lipase LipP 0.0113 0.0543 0.0738
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0106 0.0503 0.9236
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.01 0.047 0.0462
Echinococcus granulosus mitogen activated protein kinase 0.0106 0.0503 0.1204
Echinococcus granulosus beta LACTamase domain containing family member 0.0113 0.0543 0.1303
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0056 0.0874
Entamoeba histolytica hypothetical protein 0.0072 0.0309 0.5702
Brugia malayi PHD-finger family protein 0.0031 0.0074 0.018
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0055 0.086
Brugia malayi Niemann-Pick C1 protein precursor 0.01 0.0471 0.1145
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0106 0.0503 0.9236
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0113 0.0543 0.1322
Echinococcus granulosus mitogen activated protein kinase 3 0.0106 0.0503 0.1204
Echinococcus granulosus expressed conserved protein 0.0094 0.0436 0.1042
Entamoeba histolytica hypothetical protein 0.0072 0.0309 0.5702
Loa Loa (eye worm) hypothetical protein 0.0053 0.02 0.0466
Leishmania major GTP-binding protein, putative 0.0025 0.0041 0.0605
Schistosoma mansoni serine/threonine protein kinase 0.0106 0.0503 0.1323
Echinococcus granulosus Niemann Pick C1 protein 0.01 0.0471 0.1126
Loa Loa (eye worm) hypothetical protein 0.0113 0.0543 0.1303
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0219 0.029
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0025 0.0041 0.0615
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0503 0.9236
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0055 0.5534
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0534 0.9834
Echinococcus granulosus survival motor neuron protein 1 0.0739 0.4109 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.0543 1
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0106 0.0503 0.9236
Brugia malayi hypothetical protein 0.0739 0.4109 1
Loa Loa (eye worm) hypothetical protein 0.0113 0.0543 0.1303
Giardia lamblia PHD finger protein 15 0.0031 0.0074 0.1239
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0111 0.0534 0.0526
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0534 0.9834
Schistosoma mansoni importin beta-1 0.0034 0.0092 0.0223
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0092 0.1554
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0146 0.0732 0.1783
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0534 0.9834
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0219 0.021
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0072 0.0309 0.03
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.0543 0.1433
Mycobacterium tuberculosis Arylamine N-acetyltransferase Nat (arylamine acetylase) 0.129 0.7246 1
Leishmania major importin beta-1 subunit, putative 0.0027 0.0056 0.0874
Loa Loa (eye worm) hypothetical protein 0.0043 0.0145 0.0331
Entamoeba histolytica Ran family GTPase 0.0025 0.0041 0.0615
Schistosoma mansoni serine/threonine protein kinase 0.0111 0.0534 0.1409
Schistosoma mansoni hypothetical protein 0.0041 0.0136 0.0341
Echinococcus multilocularis expressed conserved protein 0.0094 0.0436 0.0427
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0009 0.5
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.01 0.0471 0.8785
Echinococcus multilocularis microtubule associated protein 2 0.0674 0.3738 0.3732
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0111 0.0273
Echinococcus multilocularis Niemann Pick C1 protein 0.01 0.0471 0.0462
Loa Loa (eye worm) hypothetical protein 0.0052 0.0198 0.0462
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.0145 0.0331
Trypanosoma cruzi polo-like protein kinase, putative 0.0111 0.0534 0.9834
Mycobacterium tuberculosis Probable lipase LipD 0.0113 0.0543 0.0738
Echinococcus multilocularis mitogen activated protein kinase 0.0106 0.0503 0.0494
Brugia malayi MAP kinase sur-1 0.0106 0.0503 0.1223
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0111 0.0534 0.1282
Loa Loa (eye worm) hypothetical protein 0.01 0.0471 0.1126
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.0543 1
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0025 0.0041 0.0605
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0052 0.0198 0.046
Leishmania major hypothetical protein, conserved 0.0113 0.0543 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0102 0.0479 0.1262
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.0145 0.0331
Schistosoma mansoni hypothetical protein 0.0179 0.0916 0.2433
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0146 0.0732 0.0724
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0074 0.0065
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0009 0.0022
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0055 0.086
Brugia malayi MH2 domain containing protein 0.0117 0.0564 0.1373
Schistosoma mansoni hypothetical protein 0.0031 0.0074 0.0175
Plasmodium vivax importin-beta 2, putative 0.0034 0.0092 0.1554
Trypanosoma brucei protein kinase, putative 0.0106 0.0503 0.9236
Echinococcus multilocularis snurportin 1 0.036 0.195 0.1943
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0106 0.0503 0.9236
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0056 0.0219 0.0533
Trypanosoma brucei polo-like protein kinase 0.0111 0.0534 0.9834
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0025 0.0041 0.0079
Echinococcus granulosus microtubule associated protein 2 0.0674 0.3738 0.9096
Schistosoma mansoni hypothetical protein 0.0151 0.0758 0.201
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0113 0.0543 0.0738
Schistosoma mansoni hypothetical protein 0.0041 0.0136 0.0341
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0025 0.0041 0.0101
Giardia lamblia Kinase, CMGC MAPK 0.0106 0.0503 0.9392
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0111 0.0248
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0111 0.0248
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.036 0.195 0.4734
Plasmodium falciparum phd finger protein, putative 0.0031 0.0074 0.7841
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0113 0.0543 0.0738
Mycobacterium ulcerans lipase LipD 0.0113 0.0543 0.0738
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0056 0.0219 0.0563
Mycobacterium leprae conserved hypothetical protein 0.0113 0.0543 0.5
Entamoeba histolytica hypothetical protein 0.0072 0.0309 0.5702
Echinococcus multilocularis survival motor neuron protein 1 0.0739 0.4109 0.4103
Mycobacterium tuberculosis Conserved protein 0.0113 0.0543 0.0738
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0503 0.9236
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0055 0.086
Mycobacterium tuberculosis Conserved protein 0.0113 0.0543 0.0738
Plasmodium falciparum importin beta, putative 0.0034 0.0092 1
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0027 0.0056 0.0874
Echinococcus multilocularis importin subunit beta 1 0.0034 0.0092 0.0083
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0074 0.1218
Brugia malayi beta-lactamase family protein 0.0113 0.0543 0.1322
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0056 0.0219 0.0512
Schistosoma mansoni patched 1 0.0043 0.0145 0.0364
Echinococcus granulosus snurportin 1 0.036 0.195 0.4734
Entamoeba histolytica hypothetical protein 0.0072 0.0309 0.5702
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0106 0.0503 0.9236
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0534 0.9834
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.0732 0.1765
Loa Loa (eye worm) hypothetical protein 0.0113 0.0543 0.1303
Loa Loa (eye worm) beta-lactamase 0.0113 0.0543 0.1303
Brugia malayi serine/threonine-protein kinase plk-2 0.0111 0.0534 0.1301
Trichomonas vaginalis CMGC family protein kinase 0.0106 0.0503 0.9236
Onchocerca volvulus 0.0113 0.0543 0.6857
Mycobacterium ulcerans hypothetical protein 0.0113 0.0543 0.0738
Loa Loa (eye worm) transcription factor SMAD2 0.0117 0.0564 0.1354
Brugia malayi Bromodomain containing protein 0.0031 0.0074 0.018
Echinococcus multilocularis beta LACTamase domain containing family member 0.0113 0.0543 0.0535
Echinococcus multilocularis lysine specific demethylase 5A 0.0037 0.0111 0.0102
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0543 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0113 0.0543 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0027 0.0056 0.0874
Echinococcus granulosus geminin 0.0179 0.0916 0.2213
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0009 0.5
Trypanosoma cruzi hypothetical protein, conserved 0.0113 0.0543 1
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0534 0.9834
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0074 0.1218
Schistosoma mansoni hypothetical protein 0.036 0.195 0.5205
Mycobacterium leprae Probable lipase LipE 0.0113 0.0543 0.5
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0113 0.0543 0.1433
Brugia malayi jmjC domain containing protein 0.01 0.047 0.1144
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0055 0.086
Loa Loa (eye worm) hypothetical protein 0.0031 0.0074 0.0159
Trypanosoma brucei hypothetical protein, conserved 0.0113 0.0543 1
Toxoplasma gondii HEAT repeat-containing protein 0.0034 0.0092 0.1554
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0111 0.0534 0.9834
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0074 0.0175
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0025 0.0041 0.0605
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.0145 0.0136
Trypanosoma cruzi polo-like protein kinase, putative 0.0111 0.0534 0.9834
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0217 0.3889
Mycobacterium tuberculosis Probable hydrolase 0.0113 0.0543 0.0738
Schistosoma mansoni ran 0.0025 0.0041 0.0087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0732 0.194
Echinococcus multilocularis jumonji domain containing protein 0.0043 0.0142 0.0133
Schistosoma mansoni survival motor neuron protein 0.0151 0.0758 0.201
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0113 0.0543 0.0738
Entamoeba histolytica hypothetical protein 0.0027 0.0056 0.0889
Schistosoma mansoni hypothetical protein 0.0041 0.0136 0.0341
Echinococcus multilocularis protein dispatched 1 0.0049 0.0179 0.0171
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0113 0.0543 0.1303
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0722 0.401 0.5529
Echinococcus multilocularis Niemann Pick C1 protein 0.0143 0.0715 0.0707
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.0145 0.2543
Brugia malayi RNA, U transporter 1 0.0096 0.0446 0.1086
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0106 0.0503 0.9236
Echinococcus granulosus jumonji domain containing protein 0.0043 0.0142 0.0325
Onchocerca volvulus Serine\/threonine kinase homolog 0.0111 0.0534 0.6727
Mycobacterium tuberculosis Probable esterase LipL 0.0113 0.0543 0.0738
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0106 0.0503 0.1204
Brugia malayi hypothetical protein 0.0072 0.0309 0.0751
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0106 0.0503 0.9236
Toxoplasma gondii ABC1 family protein 0.0113 0.0543 1
Brugia malayi CHE-14 protein 0.0043 0.0145 0.0353
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0534 0.9834
Echinococcus multilocularis protein patched 0.0043 0.0145 0.0136
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0203
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0106 0.0503 0.9236
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.0543 1
Trichomonas vaginalis ran, putative 0.0025 0.0041 0.0605
Echinococcus multilocularis geminin 0.0179 0.0916 0.0908
Schistosoma mansoni microtubule-associated protein tau 0.0674 0.3738 1
Echinococcus granulosus Protein patched homolog 1 0.0043 0.0145 0.0331
Loa Loa (eye worm) hypothetical protein 0.0739 0.4109 1
Schistosoma mansoni kinase 0.0057 0.0225 0.058
Trichomonas vaginalis D-aminoacylase, putative 0.0113 0.0543 1
Trichomonas vaginalis importin beta-1, putative 0.0027 0.0056 0.0874
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0146 0.0732 0.1765
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0055 0.5534
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0025 0.0041 0.0032
Brugia malayi Importin beta-1 subunit 0.0034 0.0092 0.0224
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0056 0.0219 0.029
Trichomonas vaginalis CAMK family protein kinase 0.0056 0.0217 0.3889
Loa Loa (eye worm) hypothetical protein 0.0113 0.0543 0.1303
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0074 0.0159
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0146 0.0732 0.1765
Trypanosoma brucei importin beta-1 subunit, putative 0.0034 0.0092 0.1554
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0151 0.0758 0.1846
Echinococcus granulosus importin subunit beta 1 0.0034 0.0092 0.0203
Brugia malayi beta-lactamase 0.0113 0.0543 0.1322
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0111 0.0273
Onchocerca volvulus 0.0113 0.0543 0.6857
Mycobacterium tuberculosis Conserved protein 0.0113 0.0543 0.0738
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0056 0.0219 0.3931
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.01 0.047 0.1125
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0534 0.9834
Schistosoma mansoni jumonji domain containing protein 0.008 0.0353 0.0922
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0055 0.086
Mycobacterium ulcerans beta-lactamase 0.0113 0.0543 0.0738
Entamoeba histolytica serine/threonine protein kinase, putative 0.0111 0.0534 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0056 0.0219 0.029
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0025 0.0041 0.0605
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0074 0.1218
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0072 0.0309 0.0731
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0146 0.0732 0.194
Leishmania major hypothetical protein, conserved 0.0027 0.0055 0.086
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0111 0.0534 0.1282
Echinococcus granulosus Niemann Pick C1 protein 0.0143 0.0715 0.1723
Brugia malayi beta-lactamase family protein 0.0113 0.0543 0.1322
Schistosoma mansoni transcription factor LCR-F1 0.0072 0.0309 0.0803
Echinococcus granulosus peregrin 0.0031 0.0074 0.0159
Loa Loa (eye worm) MH2 domain-containing protein 0.0117 0.0564 0.1354
Schistosoma mansoni hypothetical protein 0.0041 0.0136 0.0341
Mycobacterium ulcerans arylamine N-acetyltransferase Nat 0.129 0.7246 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0063 0.0259 0.0611
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0025 0.0041 0.3893
Schistosoma mansoni ran 0.0025 0.0041 0.0087

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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