Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | cysteine protease | 0.0314 | 0.5141 | 0.5141 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0215 | 0.2766 | 0.2766 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0215 | 0.2766 | 0.3182 |
Onchocerca volvulus | Cathepsin L homolog | 0.0314 | 0.5141 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0215 | 0.2766 | 0.1739 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.2766 | 0.2766 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0169 | 0.1657 | 0.1657 |
Brugia malayi | cathepsin L-like precursor | 0.0215 | 0.2766 | 0.2766 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Leishmania major | cathepsin L-like protease | 0.0314 | 0.5141 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0208 | 0.2597 | 0.2597 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0169 | 0.1657 | 0.0473 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0215 | 0.2766 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.0314 | 0.5141 | 1 |
Leishmania major | cathepsin L-like protease | 0.0314 | 0.5141 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0215 | 0.2766 | 0.2766 |
Plasmodium vivax | vivapain-1 | 0.0169 | 0.1657 | 0.3224 |
Echinococcus granulosus | cysteine protease | 0.0169 | 0.1657 | 0.0473 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0314 | 0.5141 | 0.5141 |
Brugia malayi | Cathepsin L-like precursor | 0.0314 | 0.5141 | 0.5141 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.2766 | 0.2766 |
Brugia malayi | Cathepsin L-like precursor | 0.0314 | 0.5141 | 0.5141 |
Trypanosoma cruzi | cysteine protease, putative | 0.0169 | 0.1657 | 0.1657 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0215 | 0.2766 | 0.3182 |
Onchocerca volvulus | 0.0314 | 0.5141 | 1 | |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0166 | 0.1597 | 0.1038 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Plasmodium vivax | vivapain-2 | 0.0314 | 0.5141 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0314 | 0.5141 | 0.5141 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0151 | 0.1243 | 0.1243 |
Loa Loa (eye worm) | hypothetical protein | 0.0314 | 0.5141 | 0.5141 |
Giardia lamblia | Cathepsin B precursor | 0.0208 | 0.2597 | 0.5 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0151 | 0.1243 | 0.1243 |
Echinococcus granulosus | cathepsin b | 0.0517 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0314 | 0.5141 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0314 | 0.5141 | 0.4451 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0151 | 0.1243 | 0.1243 |
Loa Loa (eye worm) | ctsf protein | 0.0314 | 0.5141 | 0.5141 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.2766 | 0.2766 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1657 | 0.1657 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0517 | 1 | 1 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0169 | 0.1657 | 0.1657 |
Giardia lamblia | Cathepsin B precursor | 0.0208 | 0.2597 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0314 | 0.5141 | 0.5141 |
Onchocerca volvulus | 0.0314 | 0.5141 | 1 | |
Leishmania major | cathepsin L-like protease | 0.0314 | 0.5141 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0517 | 1 | 1 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0166 | 0.1597 | 0.0404 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0151 | 0.1243 | 0.1243 |
Leishmania major | cysteine peptidase A (CPA) | 0.0314 | 0.5141 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0314 | 0.5141 | 0.5141 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0151 | 0.1243 | 0.5 |
Echinococcus multilocularis | serotonin transporter | 0.0151 | 0.1243 | 0.0661 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0314 | 0.5141 | 0.5141 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0208 | 0.2597 | 0.2697 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0291 | 0.4596 | 0.4237 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1657 | 0.1657 |
Leishmania major | cathepsin L-like protease | 0.0314 | 0.5141 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0314 | 0.5141 | 1 |
Onchocerca volvulus | 0.0215 | 0.2766 | 0.3906 | |
Loa Loa (eye worm) | fibroinase | 0.0314 | 0.5141 | 0.5141 |
Echinococcus granulosus | cathepsin l1 | 0.0314 | 0.5141 | 0.4451 |
Onchocerca volvulus | 0.0314 | 0.5141 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0314 | 0.5141 | 0.5141 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0314 | 0.5141 | 0.4818 |
Echinococcus multilocularis | cathepsin L | 0.0169 | 0.1657 | 0.1102 |
Onchocerca volvulus | 0.0314 | 0.5141 | 1 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0314 | 0.5141 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0253 | 0.3666 | 0.3666 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0208 | 0.2597 | 0.5 |
Echinococcus multilocularis | cathepsin b | 0.0517 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0517 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0314 | 0.5141 | 0.5141 |
Toxoplasma gondii | cathepsin CPL | 0.0314 | 0.5141 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0314 | 0.5141 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0169 | 0.1657 | 0.1657 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0314 | 0.5141 | 0.5141 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Plasmodium vivax | vivapain-3 | 0.0169 | 0.1657 | 0.3224 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0169 | 0.1657 | 0.1657 |
Echinococcus multilocularis | cysteine protease | 0.0314 | 0.5141 | 0.4818 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0314 | 0.5141 | 0.4818 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0517 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0169 | 0.1657 | 0.1657 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0291 | 0.4596 | 0.3829 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Onchocerca volvulus | 0.0314 | 0.5141 | 1 | |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0314 | 0.5141 | 0.4818 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0208 | 0.2597 | 0.2697 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Leishmania major | cathepsin L-like protease | 0.0314 | 0.5141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0151 | 0.1243 | 0.1243 |
Onchocerca volvulus | 0.0314 | 0.5141 | 1 | |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1657 | 0.1657 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0184 | 0.2029 | 0.1498 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1243 | 0.1243 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1243 | 0.1243 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0517 | 1 | 1 |
Loa Loa (eye worm) | serotonin transporter b | 0.0151 | 0.1243 | 0.1243 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0314 | 0.5141 | 0.5141 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0314 | 0.5141 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0517 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0314 | 0.5141 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0208 | 0.2597 | 0.2597 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0314 | 0.5141 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0184 | 0.2029 | 0.0897 |
Onchocerca volvulus | 0.0314 | 0.5141 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.1243 | 0.1243 |
Leishmania major | cathepsin L-like protease | 0.0314 | 0.5141 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0314 | 0.5141 | 0.4818 |
Brugia malayi | Cathepsin L-like precursor | 0.0215 | 0.2766 | 0.2766 |
Brugia malayi | Cathepsin L-like precursor | 0.0314 | 0.5141 | 0.5141 |
Echinococcus multilocularis | cathepsin b | 0.0517 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0215 | 0.2766 | 0.2766 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0314 | 0.5141 | 0.4451 |
Echinococcus granulosus | cathepsin b | 0.0517 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0314 | 0.5141 | 1 |
Leishmania major | cathepsin L-like protease | 0.0314 | 0.5141 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0314 | 0.5141 | 0.5141 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0314 | 0.5141 | 0.5141 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0208 | 0.2597 | 0.2597 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Plasmodium vivax | vivapain-2 | 0.0314 | 0.5141 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0314 | 0.5141 | 0.4818 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0215 | 0.2766 | 0.2766 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0314 | 0.5141 | 0.5141 |
Echinococcus granulosus | cathepsin L | 0.0169 | 0.1657 | 0.0473 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0169 | 0.1657 | 0.1657 |
Plasmodium vivax | unspecified product | 0.0169 | 0.1657 | 0.3224 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0314 | 0.5141 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0314 | 0.5141 | 0.5141 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0314 | 0.5141 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.