Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Cathepsin F homolog | 0.1205 | 0.3886 | 1 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Brugia malayi | fibroinase precursor | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0208 | 0.0645 | 0.0645 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Onchocerca volvulus | 0.0835 | 0.2684 | 0.6886 | |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.209 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.037 | 0.1172 | 0.1134 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0663 | 0.2123 | 0.5414 |
Onchocerca volvulus | 0.0034 | 0.008 | 0.0136 | |
Onchocerca volvulus | 0.0293 | 0.0921 | 0.2318 | |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0293 | 0.0921 | 0.2288 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0663 | 0.2123 | 0.538 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.037 | 0.1172 | 0.1172 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.037 | 0.1172 | 0.1172 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.0163 | 0.0163 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | geminin | 0.0146 | 0.0443 | 0.0443 |
Loa Loa (eye worm) | hypothetical protein | 0.3087 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0835 | 0.2684 | 0.5946 |
Brugia malayi | MH2 domain containing protein | 0.0208 | 0.0645 | 0.0645 |
Echinococcus multilocularis | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.037 | 0.1172 | 0.1172 |
Schistosoma mansoni | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0208 | 0.0645 | 0.0645 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.0004 | 0.0004 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0034 | 0.008 | 0.008 |
Brugia malayi | Papain family cysteine protease containing protein | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.0004 | 0.0004 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.001 | 0.0002 | 0.0002 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.007 | 0.007 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0064 | 0.0178 | 0.0353 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0031 | 0.007 | 0.007 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0027 | 0.0059 | 0.0059 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.209 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0002 | 0.0002 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Echinococcus granulosus | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0042 | 0.0042 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | neuropeptide receptor | 0.0216 | 0.0673 | 0.0673 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0072 | 0.0202 | 0.0202 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0018 | 0.0027 | 0.0027 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | cathepsin L precursor | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | geminin | 0.0146 | 0.0443 | 0.0443 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1205 | 0.3886 | 0.3886 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Echinococcus multilocularis | cathepsin b | 0.3087 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Plasmodium vivax | unspecified product | 0.0293 | 0.0921 | 0.2288 |
Plasmodium vivax | vivapain-2 | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0034 | 0.008 | 0.008 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0663 | 0.2123 | 0.209 |
Loa Loa (eye worm) | Smad1 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1205 | 0.3886 | 0.3886 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1157 | 0.3729 | 0.9593 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0443 | 0.0443 |
Schistosoma mansoni | hypothetical protein | 0.0059 | 0.0163 | 0.0163 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0835 | 0.2684 | 0.2684 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | cathepsin b | 0.3087 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0663 | 0.2123 | 0.4054 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.3087 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0293 | 0.0921 | 0.2288 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0293 | 0.0921 | 0.0883 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0663 | 0.2123 | 0.209 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0293 | 0.0921 | 0.2288 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1205 | 0.3886 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0087 | 0.0252 | 0.0252 |
Plasmodium vivax | vivapain-1 | 0.0663 | 0.2123 | 0.5414 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0663 | 0.2123 | 0.2123 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1205 | 0.3886 | 0.3886 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1157 | 0.3729 | 0.3703 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0663 | 0.2123 | 0.2123 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | ecdysteroid receptor | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0293 | 0.0921 | 0.2288 |
Echinococcus granulosus | cathepsin L | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | cathepsin s | 0.037 | 0.1172 | 0.1172 |
Brugia malayi | MH2 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Leishmania major | cysteine peptidase A (CPA) | 0.1205 | 0.3886 | 1 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0663 | 0.2123 | 0.2123 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0835 | 0.2684 | 0.685 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0059 | 0.0163 | 0.0163 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3087 | 1 | 1 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0663 | 0.2123 | 0.538 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0293 | 0.0921 | 0.2231 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Echinococcus granulosus | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0835 | 0.2684 | 0.2684 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Plasmodium vivax | unspecified product | 0.037 | 0.1172 | 0.2939 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.001 | 0.0003 | 0.0003 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | GPCR family 2 | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Loa Loa (eye worm) | hypothetical protein | 0.0087 | 0.0252 | 0.0252 |
Echinococcus granulosus | cathepsin l1 | 0.0835 | 0.2684 | 0.2684 |
Schistosoma mansoni | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus multilocularis | smad | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0018 | 0.0027 | 0.0027 |
Toxoplasma gondii | cathepsin CPC2 | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | cathepsin B | 0.1157 | 0.3729 | 0.3729 |
Echinococcus multilocularis | cathepsin L | 0.0663 | 0.2123 | 0.2123 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0663 | 0.2123 | 0.5414 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0293 | 0.0921 | 0.2288 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1205 | 0.3886 | 0.3886 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0835 | 0.2684 | 0.2653 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus multilocularis | cathepsin L | 0.0293 | 0.0921 | 0.0921 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Schistosoma mansoni | thyroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0293 | 0.0921 | 0.2288 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0293 | 0.0921 | 0.0883 |
Echinococcus multilocularis | Smad4 | 0.0014 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0293 | 0.0921 | 0.2231 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.001 | 0.0002 | 0.0002 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0031 | 0.007 | 0.007 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | cathepsin l1 | 0.1205 | 0.3886 | 0.3886 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0835 | 0.2684 | 0.5946 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | nuclear receptor NHR-88 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | cathepsin b | 0.3087 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | Cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | cysteine protease | 0.1205 | 0.3886 | 0.3886 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0293 | 0.0921 | 0.2288 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Plasmodium vivax | unspecified product | 0.0663 | 0.2123 | 0.5414 |
Trypanosoma cruzi | cysteine protease, putative | 0.0663 | 0.2123 | 0.209 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0293 | 0.0921 | 0.2288 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0663 | 0.2123 | 0.5414 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | GPCR, family 2 | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | MH2 domain containing protein | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | vivapain-3 | 0.0663 | 0.2123 | 0.5414 |
Echinococcus granulosus | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Brugia malayi | CXXC zinc finger family protein | 0.0034 | 0.008 | 0.008 |
Onchocerca volvulus | Cathepsin L homolog | 0.1205 | 0.3886 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0018 | 0.0027 | 0.0027 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0146 | 0.0443 | 0.0443 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1205 | 0.3886 | 0.386 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0293 | 0.0921 | 0.2288 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.037 | 0.1172 | 0.1134 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | smad | 0.0014 | 0.0016 | 0.0016 |
Brugia malayi | Smad1 | 0.0014 | 0.0016 | 0.0016 |
Schistosoma mansoni | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | dnaJ subfamily B | 0.0481 | 0.1532 | 0.1532 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0663 | 0.2123 | 0.4054 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0018 | 0.0027 | 0.0027 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Entamoeba histolytica | hypothetical protein | 0.0293 | 0.0921 | 0.2231 |
Toxoplasma gondii | cathepsin CPL | 0.1205 | 0.3886 | 1 |
Toxoplasma gondii | cathepsin B | 0.1157 | 0.3729 | 0.9593 |
Entamoeba histolytica | papain family cysteine protease domain containing protein | 0.0293 | 0.0921 | 0.2231 |
Loa Loa (eye worm) | ctsf protein | 0.1205 | 0.3886 | 0.3886 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.0004 | 0.0004 |
Plasmodium vivax | vivapain-2 | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1205 | 0.3886 | 0.3886 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0663 | 0.2123 | 0.2123 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0027 | 0.0059 | 0.0059 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0018 | 0.0027 | 0.0027 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0293 | 0.0921 | 0.2288 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.0293 | 0.0921 | 0.0921 |
Loa Loa (eye worm) | hypothetical protein | 0.037 | 0.1172 | 0.1172 |
Echinococcus granulosus | cathepsin b | 0.3087 | 1 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0087 | 0.0252 | 0.0252 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0042 | 0.0042 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0027 | 0.0059 | 0.0059 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0663 | 0.2123 | 0.538 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Cathepsin L-like precursor | 0.0835 | 0.2684 | 0.2684 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0018 | 0.0027 | 0.0027 |
Echinococcus granulosus | smad | 0.0014 | 0.0016 | 0.0016 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0481 | 0.1532 | 0.1532 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.3087 | 1 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0014 | 0.0016 | 0.0016 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0293 | 0.0921 | 0.2288 |
Brugia malayi | steroid hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Toxoplasma gondii | cathepsin CPC1 | 0.0293 | 0.0921 | 0.2288 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Echinococcus multilocularis | cpg binding protein | 0.0036 | 0.0086 | 0.0086 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0031 | 0.007 | 0.007 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0027 | 0.0059 | 0.0059 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0027 | 0.0059 | 0.0059 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | fibroinase | 0.1205 | 0.3886 | 0.3886 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0293 | 0.0921 | 0.0921 |
Brugia malayi | Cathepsin L-like precursor | 0.037 | 0.1172 | 0.1172 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1157 | 0.3729 | 0.3729 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0018 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0293 | 0.0921 | 0.0921 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0027 | 0.0059 | 0.0059 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Leishmania major | cathepsin L-like protease | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | coup transcription factor | 0.0018 | 0.0027 | 0.0027 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0014 | 0.0016 | 0.0016 |
Echinococcus granulosus | cathepsin L | 0.0663 | 0.2123 | 0.2123 |
Brugia malayi | Cathepsin L-like precursor | 0.1205 | 0.3886 | 0.3886 |
Loa Loa (eye worm) | hypothetical protein | 0.1205 | 0.3886 | 0.3886 |
Echinococcus granulosus | cysteine protease | 0.0663 | 0.2123 | 0.2123 |
Brugia malayi | hypothetical protein | 0.0031 | 0.007 | 0.007 |
Giardia lamblia | Cathepsin B precursor | 0.1157 | 0.3729 | 1 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0014 | 0.0016 | 0.0016 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0018 | 0.0027 | 0.0027 |
Schistosoma mansoni | cathepsin C | 0.0293 | 0.0921 | 0.0921 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0216 | 0.0673 | 0.0673 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.1157 | 0.3729 | 0.9593 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.1205 | 0.3886 | 0.386 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 0.2684 | 0.2684 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0293 | 0.0921 | 0.2288 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0087 | 0.0252 | 0.0252 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.1205 | 0.3886 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1157 | 0.3729 | 0.9472 |
Schistosoma mansoni | hypothetical protein | 0.0481 | 0.1532 | 0.1532 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0293 | 0.0921 | 0.2288 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1205 | 0.3886 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Brugia malayi | nuclear hormone receptor | 0.0018 | 0.0027 | 0.0027 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0016 | 0.0016 |
Onchocerca volvulus | Cathepsin L homolog | 0.0293 | 0.0921 | 0.2318 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0018 | 0.0027 | 0.0027 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0293 | 0.0921 | 0.2288 |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Onchocerca volvulus | Cathepsin L homolog | 0.1205 | 0.3886 | 1 |
Onchocerca volvulus | 0.1205 | 0.3886 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0663 | 0.2123 | 0.538 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0027 | 0.0027 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ED50 (functional) | > 200 mg kg-1 | Antiwrithing activity in po dosed mouse assessed as prevention of phenyl-p-benzoquinone-induced abdominal constriction response | ChEMBL. | 31481 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.