TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 351.484 | Formula: C19H33N3O3
H donors: 4 H acceptors: 2 LogP: 2.13 Rotable bonds: 13
Rule of 5 violations (Lipinski): 1
SMILES: CCCNC(=O)NCCc1ccc(cc1)OCC(CNC(C)(C)C)O
InChi: 1S/C19H33N3O3/c1-5-11-20-18(24)21-12-10-15-6-8-17(9-7-15)25-14-16(23)13-22-19(2,3)4/h6-9,16,22-23H,5,10-14H2,1-4H3,(H2,20,21,24)
InChiKey: AABZNODCCBJWSB-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0547	0.1079	0.2276
Entamoeba histolytica	cysteine proteinase, putative	0.1282	0.2563	0.5407
Brugia malayi	Cathepsin L-like precursor	0.1625	0.3255	0.3255
Onchocerca volvulus	Cathepsin L homolog	0.0547	0.1079	0.2276
Loa Loa (eye worm)	fibroinase	0.236	0.4739	0.4739
Loa Loa (eye worm)	hypothetical protein	0.0735	0.1459	0.1459
Plasmodium vivax	dipeptidyl aminopeptidase 3, putative	0.0547	0.1079	0.2276
Echinococcus granulosus	cathepsin b	0.4965	1	1
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0547	0.1079	0.2276
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0547	0.1079	0.2276
Echinococcus multilocularis	cathepsin L cysteine protease	0.236	0.4739	0.4739
Trypanosoma cruzi	cysteine peptidase, putative	0.1282	0.2563	0.1663
Onchocerca volvulus		0.236	0.4739	1
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.236	0.4739	0.4739
Brugia malayi	cathepsin L precursor	0.0547	0.1079	0.1079
Brugia malayi	cathepsin F-like cysteine proteinase	0.0547	0.1079	0.1079
Giardia lamblia	Cathepsin B precursor	0.1913	0.3838	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Loa Loa (eye worm)	hypothetical protein	0.0547	0.1079	0.1079
Brugia malayi	Cathepsin L-like precursor	0.236	0.4739	0.4739
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Plasmodium falciparum	serine repeat antigen 8	0.0547	0.1079	0.2276
Trypanosoma cruzi	cruzipain precursor, putative	0.0735	0.1459	0.0426
Loa Loa (eye worm)	cysteine proteinase cathepsin Z	0.0547	0.1079	0.1079
Loa Loa (eye worm)	hypothetical protein	0.0547	0.1079	0.1079
Plasmodium falciparum	serine repeat antigen 9	0.0547	0.1079	0.2276
Brugia malayi	Papain family cysteine protease containing protein	0.0547	0.1079	0.1079
Chlamydia trachomatis	ABC transporter ATP binding protein/permease	0.0013	0	0.5
Entamoeba histolytica	cysteine protease, putative	0.0547	0.1079	0.2276
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.4965	1	1
Plasmodium falciparum	cysteine proteinase falcipain 2b	0.236	0.4739	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0547	0.1079	0.2276
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0547	0.1079	0.1079
Leishmania major	cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like	0.1913	0.3838	0.8098
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Loa Loa (eye worm)	Papain cysteine protease/cathepsin propeptide inhibitor-containing protein	0.236	0.4739	0.4739
Loa Loa (eye worm)	hypothetical protein	0.0547	0.1079	0.1079
Entamoeba histolytica	cysteine proteinase, putative	0.1625	0.3255	0.6869
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.1913	0.3838	0.3093
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0547	0.1079	0.1079
Brugia malayi	cathepsin L-like cysteine proteinase, identical	0.0735	0.1459	0.1458
Onchocerca volvulus	Cathepsin F homolog	0.236	0.4739	1
Brugia malayi	Cathepsin L-like precursor	0.236	0.4739	0.4739
Brugia malayi	Papain family cysteine protease containing protein	0.1282	0.2563	0.2563
Schistosoma mansoni	cathepsin B (C01 family)	0.0547	0.1079	0.1079
Plasmodium falciparum	dipeptidyl aminopeptidase 3	0.0547	0.1079	0.2276
Onchocerca volvulus		0.236	0.4739	1
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Onchocerca volvulus		0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1282	0.2563	0.5407
Loa Loa (eye worm)	ctsf protein	0.236	0.4739	0.4739
Loa Loa (eye worm)	hypothetical protein	0.0735	0.1459	0.1459
Toxoplasma gondii	cathepsin B	0.1913	0.3838	0.8098
Plasmodium falciparum	cysteine proteinase falcipain 1	0.1282	0.2563	0.5407
Trichomonas vaginalis	conserved hypothetical protein	0.0547	0.1079	0.2276
Loa Loa (eye worm)	hypothetical protein	0.1625	0.3255	0.3255
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Leishmania major	cathepsin L-like protease	0.236	0.4739	1
Echinococcus multilocularis	cysteine protease	0.236	0.4739	0.4739
Onchocerca volvulus		0.236	0.4739	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Trypanosoma cruzi	cysteine peptidase (N-terminal), putative	0.1282	0.2563	0.1663
Echinococcus multilocularis	cysteine protease	0.236	0.4739	0.4739
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.236	0.4739	1
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.1913	0.3838	0.3838
Trypanosoma cruzi	cysteine peptidase, putative	0.236	0.4739	0.4103
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.236	0.4739	1
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Toxoplasma gondii	cathepsin CPC1	0.0547	0.1079	0.2276
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.236	0.4739	1
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.1282	0.2563	0.2563
Plasmodium falciparum	cysteine proteinase falcipain 3	0.236	0.4739	1
Echinococcus granulosus	cathepsin l1	0.236	0.4739	0.4739
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1625	0.3255	0.6869
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0547	0.1079	0.2276
Brugia malayi	Papain family cysteine protease containing protein	0.1282	0.2563	0.2563
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Echinococcus multilocularis	cathepsin b	0.4965	1	1
Entamoeba histolytica	cysteine protease, putative	0.0547	0.1079	0.2276
Trypanosoma cruzi	cysteine peptidase, putative	0.236	0.4739	0.4103
Plasmodium falciparum	serine repeat antigen 2	0.0547	0.1079	0.2276
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Schistosoma mansoni	cathepsin F (C01 family)	0.1625	0.3255	0.3255
Schistosoma mansoni	cathepsin F (C01 family)	0.236	0.4739	0.4739
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Leishmania major	cathepsin L-like protease	0.236	0.4739	1
Plasmodium vivax	vivapain-3	0.1282	0.2563	0.5407
Plasmodium falciparum	serine repeat antigen 4	0.0547	0.1079	0.2276
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1282	0.2563	0.5407
Plasmodium falciparum	dipeptidyl aminopeptidase 1	0.0547	0.1079	0.2276
Plasmodium falciparum	serine repeat antigen 3	0.0547	0.1079	0.2276
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0547	0.1079	0.1079
Onchocerca volvulus		0.236	0.4739	1
Entamoeba histolytica	hypothetical protein	0.0547	0.1079	0.2276
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0735	0.1459	0.1459
Brugia malayi	Papain family cysteine protease containing protein	0.0547	0.1079	0.1079
Entamoeba histolytica	cysteine protease, putative	0.0547	0.1079	0.2276
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.236	0.4739	0.4739
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0547	0.1079	0.2276
Entamoeba histolytica	cysteine proteinase, putative	0.1282	0.2563	0.5407
Trichomonas vaginalis	Clan CA, family C1, cathepsin F-like cysteine peptidase	0.0547	0.1079	0.2276
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.236	0.4739	1
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Schistosoma mansoni	cathepsin F (C01 family)	0.236	0.4739	0.4739
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Brugia malayi	cathepsin F-like cysteine proteinase	0.0735	0.1459	0.1458
Entamoeba histolytica	cysteine proteinase, putative	0.1282	0.2563	0.5407
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Echinococcus granulosus	cathepsin L	0.0547	0.1079	0.1079
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.0547	0.1079	0.2276
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.1625	0.3255	0.6869
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0547	0.1079	0.1079
Toxoplasma gondii	cathepsin CPL	0.236	0.4739	1
Trypanosoma cruzi	cysteine peptidase, putative	0.236	0.4739	0.4103
Echinococcus granulosus	cathepsin L cysteine protease	0.1282	0.2563	0.2563
Plasmodium vivax	serine-repeat antigen 3 (SERA)	0.0547	0.1079	0.2276
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Plasmodium vivax	serine-repeat antigen (SERA)	0.0547	0.1079	0.2276
Echinococcus multilocularis	cathepsin L	0.1282	0.2563	0.2563
Echinococcus granulosus	cathepsin L	0.1282	0.2563	0.2563
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Leishmania major	cathepsin L-like protease	0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0547	0.1079	0.2276
Loa Loa (eye worm)	hypothetical protein	0.4965	1	1
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0547	0.1079	0.1079
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Entamoeba histolytica	papain family cysteine protease domain containing protein	0.0547	0.1079	0.2276
Plasmodium vivax	unspecified product	0.0547	0.1079	0.2276
Echinococcus multilocularis	cathepsin L cysteine protease	0.236	0.4739	0.4739
Leishmania major	cathepsin L-like protease	0.236	0.4739	1
Plasmodium vivax	serine-repeat antigen 2 (SERA)	0.0547	0.1079	0.2276
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Brugia malayi	Papain family cysteine protease containing protein	0.0547	0.1079	0.1079
Onchocerca volvulus	Cathepsin L homolog	0.236	0.4739	1
Trypanosoma cruzi	cysteine protease, putative	0.1282	0.2563	0.1663
Entamoeba histolytica	cysteine proteinase 2	0.1282	0.2563	0.5407
Leishmania major	cathepsin L-like protease	0.236	0.4739	1
Leishmania major	cathepsin L-like protease	0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.236	0.4739	1
Toxoplasma gondii	cathepsin CPC2	0.0547	0.1079	0.2276
Trypanosoma cruzi	cysteine peptidase, clan CA, family C1, cathepsin L-like, putative	0.1625	0.3255	0.244
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.1913	0.3838	0.8098
Entamoeba histolytica	cysteine protease, putative	0.236	0.4739	1
Entamoeba histolytica	cysteine proteinase 1, putative	0.1282	0.2563	0.5407
Entamoeba histolytica	papain family cysteine protease domain containing protein	0.0547	0.1079	0.2276
Brugia malayi	cathepsin L-like cysteine proteinase	0.0547	0.1079	0.1079
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Brugia malayi	Cathepsin L-like precursor	0.0735	0.1459	0.1458
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Plasmodium vivax	serine-repeat antigen 4 (SERA), putative	0.0547	0.1079	0.2276
Entamoeba histolytica	cysteine proteinase, putative	0.236	0.4739	1
Plasmodium vivax	vivapain-1	0.1282	0.2563	0.5407
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Giardia lamblia	Cathepsin B precursor	0.1913	0.3838	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0547	0.1079	0.2276
Brugia malayi	Cathepsin L-like precursor	0.236	0.4739	0.4739
Schistosoma mansoni	dipeptidyl-peptidase I (C01 family)	0.0547	0.1079	0.1079
Brugia malayi	Cathepsin L-like cysteine proteinase	0.1625	0.3255	0.3255
Plasmodium falciparum	dipeptidyl aminopeptidase 2	0.0547	0.1079	0.2276
Trypanosoma cruzi	cysteine peptidase C (CPC), putative	0.4965	1	1
Trypanosoma cruzi	cruzipain precursor, putative	0.236	0.4739	0.4103
Leishmania major	cysteine peptidase A (CPA)	0.236	0.4739	1
Brugia malayi	cathepsin L-like precursor	0.1625	0.3255	0.3255
Toxoplasma gondii	preprocathepsin c precursor, putative	0.0547	0.1079	0.2276
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0547	0.1079	0.2276
Plasmodium vivax	unspecified product	0.0735	0.1459	0.3077
Trypanosoma brucei	cysteine peptidase C (CPC)	0.1913	0.3838	0.5858
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Loa Loa (eye worm)	cysteine protease	0.236	0.4739	0.4739
Onchocerca volvulus		0.1625	0.3255	0.6869
Loa Loa (eye worm)	hypothetical protein	0.1625	0.3255	0.3255
Mycobacterium tuberculosis	Probable transmembrane multidrug efflux pump	0.0013	0	0.5
Trichomonas vaginalis	Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase	0.0547	0.1079	0.2276
Trichomonas vaginalis	conserved hypothetical protein	0.0547	0.1079	0.2276
Trypanosoma cruzi	cysteine proteinase, putative	0.1282	0.2563	0.1663
Giardia lamblia	Cathepsin B precursor	0.1913	0.3838	1
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Loa Loa (eye worm)	hypothetical protein	0.236	0.4739	0.4739
Schistosoma mansoni	cathepsin s	0.0735	0.1459	0.1458
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0547	0.1079	0.2276
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0547	0.1079	0.1079
Onchocerca volvulus	Cathepsin L homolog	0.236	0.4739	1
Echinococcus granulosus	cysteine protease	0.1282	0.2563	0.2563
Plasmodium vivax	vivapain-2	0.236	0.4739	1
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.1282	0.2563	0.2563
Plasmodium falciparum	serine repeat antigen 1	0.0547	0.1079	0.2276
Loa Loa (eye worm)	hypothetical protein	0.1625	0.3255	0.3255
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.4965	1	1
Echinococcus multilocularis	cathepsin L	0.0547	0.1079	0.1079
Entamoeba histolytica	cysteine protease, putative	0.0547	0.1079	0.2276
Plasmodium vivax	unspecified product	0.1282	0.2563	0.5407
Plasmodium vivax	vivapain-2	0.236	0.4739	1
Plasmodium falciparum	cysteine proteinase falcipain 2a	0.236	0.4739	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0547	0.1079	0.1079
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.236	0.4739	1
Entamoeba histolytica	cysteine protease, putative	0.0547	0.1079	0.2276
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Plasmodium vivax	serine-repeat antigen (SERA)	0.0547	0.1079	0.2276
Trypanosoma cruzi	cysteine peptidase, putative	0.0735	0.1459	0.0426
Loa Loa (eye worm)	hypothetical protein	0.0547	0.1079	0.1079
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.0547	0.1079	0.1079
Trichomonas vaginalis	Clan CA, family C1, cathepsin B-like cysteine peptidase	0.0547	0.1079	0.2276
Onchocerca volvulus		0.236	0.4739	1
Echinococcus multilocularis	cathepsin b	0.4965	1	1
Onchocerca volvulus		0.0547	0.1079	0.2276
Brugia malayi	Cathepsin L-like precursor	0.1625	0.3255	0.3255
Trypanosoma cruzi	cysteine peptidase, putative	0.236	0.4739	0.4103
Loa Loa (eye worm)	hypothetical protein	0.0735	0.1459	0.1459
Plasmodium vivax	serine-repeat antigen (SERA), putative	0.0547	0.1079	0.2276
Plasmodium vivax	serine-repeat antigen 5 (SERA)	0.0547	0.1079	0.2276
Entamoeba histolytica	cysteine protease, putative	0.0547	0.1079	0.2276
Plasmodium vivax	serine-repeat antigen 4 (SERA)	0.0547	0.1079	0.2276
Onchocerca volvulus		0.236	0.4739	1
Echinococcus multilocularis	cathepsin l cysteine peptidase	0.236	0.4739	0.4739
Loa Loa (eye worm)	hypothetical protein	0.0547	0.1079	0.1079
Loa Loa (eye worm)	papain family cysteine protease containing protein	0.0547	0.1079	0.1079
Brugia malayi	cahepsin L-like non-peptiedase homolog	0.0547	0.1079	0.1079
Plasmodium falciparum	serine repeat antigen 7	0.0547	0.1079	0.2276
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.236	0.4739	1
Echinococcus granulosus	cathepsin l1	0.1625	0.3255	0.3255
Schistosoma mansoni	SmCL2-like peptidase (C01 family)	0.1282	0.2563	0.2563
Entamoeba histolytica	cysteine proteinase, putative	0.1282	0.2563	0.5407
Loa Loa (eye worm)	hypothetical protein	0.0547	0.1079	0.1079
Plasmodium falciparum	serine repeat antigen 5	0.0547	0.1079	0.2276
Schistosoma mansoni	cathepsin S (C01 family)	0.0547	0.1079	0.1079
Schistosoma mansoni	subfamily C1A unassigned peptidase (C01 family)	0.0547	0.1079	0.1079
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0547	0.1079	0.2276
Entamoeba histolytica	cysteine proteinase, putative	0.236	0.4739	1
Brugia malayi	cathepsin Z-like cysteine proteinase	0.0547	0.1079	0.1079
Trypanosoma cruzi	cysteine proteinase, putative	0.1282	0.2563	0.1663
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.236	0.4739	1
Plasmodium vivax	dipeptidyl aminopeptidase 1, putative	0.0547	0.1079	0.2276
Brugia malayi	Cathepsin L-like precursor	0.236	0.4739	0.4739
Brugia malayi	Cathepsin L-like precursor	0.236	0.4739	0.4739
Echinococcus granulosus	cathepsin L cysteine proteinase	0.236	0.4739	0.4739
Trichomonas vaginalis	Clan CA, family C1, cathepsin L-like cysteine peptidase	0.0547	0.1079	0.2276
Plasmodium vivax	dipeptidyl aminopeptidase 2, putative	0.0547	0.1079	0.2276
Leishmania major	cathepsin L-like protease	0.236	0.4739	1
Schistosoma mansoni	cathepsin B-like peptidase (C01 family)	0.4965	1	1
Loa Loa (eye worm)	cathepsin B	0.1913	0.3838	0.3838
Leishmania major	cathepsin L-like protease	0.236	0.4739	1
Brugia malayi	Cathepsin L-like precursor	0.236	0.4739	0.4739
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or H-like cysteine peptidase	0.0547	0.1079	0.2276
Brugia malayi	Papain family cysteine protease containing protein	0.236	0.4739	0.4739
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Trichomonas vaginalis	Clan CA, family C1, papain-like cysteine peptidase	0.236	0.4739	1
Echinococcus granulosus	cathepsin l cysteine peptidase	0.236	0.4739	0.4739
Trypanosoma brucei	cysteine peptidase, Clan CA, family C1, Cathepsin L-like	0.236	0.4739	1
Entamoeba histolytica	cysteine protease, putative	0.1282	0.2563	0.5407
Plasmodium falciparum	serine repeat antigen 6	0.0547	0.1079	0.2276
Schistosoma mansoni	SmCB2 peptidase (C01 family)	0.4965	1	1
Schistosoma mansoni	subfamily C1A non-peptidase homologue (C01 family)	0.0547	0.1079	0.1079
Trichomonas vaginalis	Clan CA, family C1, cathepsin H-like cysteine peptidase	0.0547	0.1079	0.2276
Trichomonas vaginalis	Clan CA, family C1, cathepsin L or K-like cysteine peptidase	0.236	0.4739	1
Echinococcus granulosus	cathepsin b	0.4965	1	1
Brugia malayi	fibroinase precursor	0.0547	0.1079	0.1079
Schistosoma mansoni	cathepsin C	0.0547	0.1079	0.1079

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3275028

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 1906576