Detailed information for compound 1914319

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 1062.27 | Formula: C47H83N17O11
  • H donors: 13 H acceptors: 11 LogP: -2.19 Rotable bonds: 42
    Rule of 5 violations (Lipinski): 4
  • SMILES: CC(C[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N)CC(C)C)C)C)C)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)C)CCCNC(=N)N)CCCNC(=N)N)C
  • InChi: 1S/C47H83N17O11/c1-24(2)21-32(37(48)67)61-43(73)34-15-11-19-63(34)36(66)23-55-38(68)26(5)56-39(69)27(6)57-40(70)28(7)58-42(72)33(22-25(3)4)62-41(71)30(13-9-17-53-46(49)50)60-44(74)35-16-12-20-64(35)45(75)31(59-29(8)65)14-10-18-54-47(51)52/h24-28,30-35H,9-23H2,1-8H3,(H2,48,67)(H,55,68)(H,56,69)(H,57,70)(H,58,72)(H,59,65)(H,60,74)(H,61,73)(H,62,71)(H4,49,50,53)(H4,51,52,54)/t26-,27-,28-,30-,31-,32-,33-,34-,35-/m0/s1
  • InChiKey: VUJRMUZVKNJMGQ-MYORVSQBSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens apelin receptor Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi follicle stimulating hormone receptor apelin receptor 380 aa 325 aa 23.1 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0053 0.0227 0.0338
Echinococcus multilocularis smad 0.0026 0.0064 0.0063
Echinococcus granulosus g protein coupled receptor 0.006 0.0272 0.0405
Onchocerca volvulus 0.006 0.0272 0.0405
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0034 0.0111 0.0593
Loa Loa (eye worm) hepatopoietin HPO2 0.0035 0.0117 0.0175
Schistosoma mansoni lamin 0.0055 0.0243 0.028
Schistosoma mansoni patched 1 0.0045 0.0182 0.0209
Plasmodium falciparum pyruvate kinase 0.0071 0.0337 0.6454
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0065 0.0085
Echinococcus granulosus neuropeptide receptor 0.006 0.0272 0.0405
Echinococcus granulosus histone acetyltransferase KAT2B 0.0036 0.0124 0.0184
Echinococcus granulosus pyruvate kinase 0.0036 0.0128 0.019
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0042 0.0163 0.0188
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0053 0.0227 0.4297
Loa Loa (eye worm) hypothetical protein 0.0094 0.048 0.0717
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Brugia malayi neuropeptide F receptor 0.006 0.0272 0.0405
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0023 0.0047 0.0223
Mycobacterium ulcerans hypothetical protein 0.007 0.0331 0.0684
Onchocerca volvulus 0.006 0.0272 0.0405
Brugia malayi CHE-14 protein 0.0045 0.0182 0.027
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Onchocerca volvulus 0.006 0.0272 0.0405
Brugia malayi nuclear receptor NHR-67 0.0045 0.0178 0.0265
Echinococcus multilocularis GA binding protein alpha chain 0.0077 0.0377 0.0376
Echinococcus granulosus GPCR family 2 0.0034 0.0111 0.0165
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0025 0.0061 0.009
Brugia malayi Flap endonuclease-1 0.0028 0.0076 0.0113
Loa Loa (eye worm) hypothetical protein 0.007 0.0331 0.0494
Loa Loa (eye worm) hypothetical protein 0.035 0.2032 0.3038
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0094 0.048 0.0717
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0111 0.0584 0.0872
Trichomonas vaginalis glycogen phosphorylase, putative 0.1118 0.6687 1
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0008 0.00000021976
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Onchocerca volvulus 0.0128 0.0686 0.1025
Brugia malayi nuclear receptor RXR 0.0045 0.0178 0.0265
Echinococcus granulosus neuropeptides capa receptor 0.006 0.0272 0.0405
Plasmodium falciparum flap endonuclease 1 0.0028 0.0076 0.1341
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0022
Schistosoma mansoni neuropeptide F-like receptor 0.006 0.0272 0.0313
Schistosoma mansoni polycystin 1-related 0.0021 0.0036 0.0041
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB 0.0023 0.0045 0.0079
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0017 0.0008 0.0009
Loa Loa (eye worm) flap endonuclease-1 0.0028 0.0076 0.0113
Loa Loa (eye worm) prolyl oligopeptidase 0.0017 0.0008 0.0011
Echinococcus granulosus tachykinin peptides receptor 99D 0.006 0.0272 0.0405
Trypanosoma brucei cation-transporting ATPase, putative 0.0017 0.0008 0.0001
Brugia malayi Steroid receptor seven-up type 2 0.0094 0.048 0.0717
Brugia malayi hypothetical protein 0.006 0.0272 0.0405
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0022 0.0082
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0632 0.3743 0.5597
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0148 0.0803
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0222 0.0256
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus neutral alpha glucosidase AB 0.0114 0.06 0.0896
Loa Loa (eye worm) latrophilin receptor protein 2 0.0034 0.0111 0.0165
Plasmodium vivax P-type ATPase4, putative 0.0053 0.0227 0.4375
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.006 0.0272 0.0313
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0224 0.1235
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0094 0.048 0.0717
Onchocerca volvulus 0.006 0.0272 0.0405
Echinococcus multilocularis geminin 0.0854 0.509 0.5089
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0065 0.0085
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.005 0.021 0.0313
Toxoplasma gondii hypothetical protein 0.0049 0.0205 0.2934
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0065 0.0325
Schistosoma mansoni intermediate filament proteins 0.0055 0.0243 0.028
Schistosoma mansoni jun-related protein 0.0067 0.0314 0.0362
Trypanosoma brucei P-type H+-ATPase, putative 0.0033 0.0111 0.0589
Entamoeba histolytica pyruvate kinase, putative 0.0049 0.0207 0.0297
Echinococcus multilocularis ecdysone induced protein 78C 0.0094 0.048 0.0479
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0094 0.048 0.0479
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0046 0.0189 0.1037
Loa Loa (eye worm) acetyltransferase 0.0121 0.0643 0.096
Echinococcus multilocularis tachykinin peptides receptor 99D 0.006 0.0272 0.0271
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0008 0.0119
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0111 0.1596
Leishmania major alpha glucosidase II subunit, putative 0.0114 0.06 0.3393
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.006 0.0272 0.0271
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0272 0.0313
Schistosoma mansoni pyruvate kinase 0.0071 0.0337 0.0388
Brugia malayi Latrophilin receptor protein 2 0.0034 0.0111 0.0165
Schistosoma mansoni neuropeptide receptor 0.006 0.0272 0.0313
Onchocerca volvulus 0.007 0.0331 0.0494
Echinococcus multilocularis g-protein coupled receptor 0.006 0.0272 0.0271
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0022 0.0021
Mycobacterium tuberculosis Probable lipase LipE 0.007 0.0331 0.0691
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0121 0.0643 0.0742
Loa Loa (eye worm) isocitrate dehydrogenase 0.0034 0.0111 0.0166
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0128 0.0686 0.1435
Brugia malayi hypothetical protein 0.0027 0.0071 0.0105
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0027 0.0069 0.0069
Brugia malayi Nuclear hormone receptor-like 1 0.0094 0.048 0.0717
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.004 0.0148 1
Echinococcus multilocularis glycogen phosphorylase 0.1118 0.6687 0.6687
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0304 0.1751 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0111 0.0111
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0272 0.0313
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0272 0.0271
Onchocerca volvulus 0.0055 0.0243 0.0362
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.001 0.001
Trichomonas vaginalis set domain proteins, putative 0.072 0.4273 0.6386
Echinococcus granulosus GA binding protein alpha chain 0.0077 0.0377 0.0563
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0021
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0021 0.0035 0.004
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0148 0.0803
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0091 0.0458 0.0457
Toxoplasma gondii type I fatty acid synthase, putative 0.002 0.0029 0.0421
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0331 0.1854
Trypanosoma brucei calcium-translocating P-type ATPase 0.0042 0.0163 0.0889
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0045 0.0178 0.0265
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA 0.0028 0.0079 0.0149
Echinococcus multilocularis voltage dependent calcium channel 0.0085 0.0425 0.0424
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.006 0.0272 0.0313
Entamoeba histolytica hypothetical protein 0.0075 0.0361 0.0528
Loa Loa (eye worm) hypothetical protein 0.0053 0.0227 0.0338
Loa Loa (eye worm) hypothetical protein 0.0533 0.3139 0.4693
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0066 0.0305 0.0455
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0036 0.0053
Schistosoma mansoni hypothetical protein 0.0051 0.0215 0.0248
Schistosoma mansoni lozenge 0.0055 0.0244 0.0281
Brugia malayi neuropeptide F receptor 0.006 0.0272 0.0405
Schistosoma mansoni rab6-interacting 0.0021 0.0036 0.0041
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.007 0.0334 0.4787
Trypanosoma cruzi hypothetical protein, conserved 0.0101 0.0517 0.292
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.006 0.0272 0.0313
Toxoplasma gondii exonuclease III APE 0.0019 0.0022 0.032
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0001 0.000000044271
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0272 0.0271
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.006 0.0272 0.0405
Onchocerca volvulus 0.072 0.4274 0.6391
Echinococcus multilocularis G protein coupled receptor 139 0.006 0.0272 0.0271
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.003 0.0087 0.013
Mycobacterium tuberculosis Probable peptidase 0.0017 0.0008 0.0007
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1838 0.274
Echinococcus granulosus Glycosyl transferase family 35 0.1118 0.6687 1
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0085 0.0425 0.0634
Echinococcus multilocularis sex peptide receptor 0.006 0.0272 0.0271
Brugia malayi hypothetical protein 0.006 0.0272 0.0405
Brugia malayi MH1 domain containing protein 0.0026 0.0064 0.0094
Brugia malayi E1-E2 ATPase family protein 0.0017 0.0008 0.0011
Onchocerca volvulus Pyruvate kinase homolog 0.0071 0.0337 0.0502
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0093
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0094 0.048 0.0479
Trichomonas vaginalis adenylate cyclase, putative 0.0026 0.0065 0.0085
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0011
Brugia malayi Pyruvate kinase, M2 isozyme 0.0071 0.0337 0.0502
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0085 0.0425 0.0634
Loa Loa (eye worm) hypothetical protein 0.0048 0.0201 0.03
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0094 0.048 0.0717
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0053 0.0227 0.0328
Brugia malayi latrophilin 2 splice variant baaae 0.0073 0.0348 0.0519
Schistosoma mansoni ATPase 0.0053 0.0227 0.0261
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0026 0.0065 0.0085
Loa Loa (eye worm) hypothetical protein 0.007 0.0331 0.0494
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0016 0.0148
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0042 0.0163 0.2336
Schistosoma mansoni adenoreceptor 0.006 0.0272 0.0313
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0053 0.0227 0.0226
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0182 0.026
Brugia malayi ORL1-like opioid receptor 0.006 0.0272 0.0405
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1838 0.274
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0008 0.0136
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0042 0.0163 0.0889
Trypanosoma cruzi hypothetical protein, conserved 0.0114 0.06 0.3393
Onchocerca volvulus 0.0091 0.0458 0.0683
Mycobacterium ulcerans polyketide synthase 0.0028 0.0079 0.0149
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0155 0.0851 0.1783
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0272 0.0405
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0025
Schistosoma mansoni hypothetical protein 0.006 0.0272 0.0313
Echinococcus multilocularis glycoprotein Antigen 5 0.0021 0.0035 0.0034
Mycobacterium leprae Possible regulatory protein 0.0026 0.0065 0.012
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0008 0.0009
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0054 0.0236 0.1307
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0698 0.1461
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0052 0.01
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0483 0.2839 0.599
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0279
Schistosoma mansoni loxhd1 0.0021 0.0036 0.0041
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription factor 0.0082 0.0407 0.0407
Loa Loa (eye worm) voltage-dependent calcium channel 0.0022 0.0044 0.0064
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0022 0.0021
Toxoplasma gondii P-type ATPase PMA1 0.0033 0.0111 0.1586
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0152 0.083 0.124
Trichomonas vaginalis maltase-glucoamylase, putative 0.0042 0.0165 0.0235
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.006 0.0272 0.0405
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0148 0.0209
Schistosoma mansoni flap endonuclease-1 0.0025 0.006 0.0069
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0296 0.061
Onchocerca volvulus Protein ultraspiracle homolog 0.0094 0.048 0.0717
Brugia malayi Membrane calcium atpase protein 3 0.0042 0.0163 0.0243
Schistosoma mansoni amine GPCR 0.006 0.0272 0.0313
Trichomonas vaginalis amylase, putative 0.0039 0.0145 0.0205
Loa Loa (eye worm) RecQ helicase 0.0023 0.0046 0.0068
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.021 0.0313
Brugia malayi carbohydrate phosphorylase 0.1118 0.6687 1
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0064 0.0296 0.0342
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0011
Echinococcus multilocularis Mastin 0.0021 0.0035 0.0034
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Echinococcus multilocularis neuropeptide Y receptor 0.006 0.0272 0.0271
Echinococcus granulosus orexin receptor type 2 0.006 0.0272 0.0405
Schistosoma mansoni neuropeptide f receptor 76f 0.006 0.0272 0.0313
Brugia malayi AMP-binding enzyme family protein 0.0033 0.011 0.0163
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1838 0.274
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0053 0.0227 0.1255
Brugia malayi prolyl oligopeptidase family protein 0.0209 0.1177 0.1759
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0101 0.0517 1
Brugia malayi ecdysone receptor 0.0045 0.0178 0.0265
Trypanosoma brucei hypothetical protein, conserved 0.007 0.0331 0.1854
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Brugia malayi Death domain containing protein 0.0015 0.0001 0.000000057292
Schistosoma mansoni starch branching enzyme II 0.0017 0.0013 0.0014
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0272 0.0313
Loa Loa (eye worm) hypothetical protein 0.0087 0.0437 0.0653
Schistosoma mansoni hypothetical protein 0.0021 0.0036 0.0041
Schistosoma mansoni sodium / potassium ATPase beta chain 0.0327 0.1894 0.2188
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0167 0.091
Leishmania major hypothetical protein, conserved 0.007 0.0331 0.1854
Brugia malayi Nuclear hormone receptor-like 1 0.005 0.021 0.0313
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.005 0.021 0.0242
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE 0.0019 0.0021 0.0027
Toxoplasma gondii aldehyde dehydrogenase 0.013 0.0698 1
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0036 0.0124 0.0173
Plasmodium vivax pyruvate kinase 2, putative 0.0036 0.0128 0.2455
Brugia malayi AKH receptor 0.006 0.0272 0.0405
Echinococcus multilocularis neutral alpha glucosidase AB 0.0114 0.06 0.0599
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0082
Mycobacterium ulcerans lipase LipD 0.007 0.0331 0.0684
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0017 0.0008 0.0007
Mycobacterium leprae PROBABLE THIOESTERASE TESA 0.0024 0.005 0.0089
Brugia malayi calcium ATPase 0.0023 0.0047 0.0069
Mycobacterium tuberculosis Conserved protein 0.007 0.0331 0.0691
Echinococcus granulosus serotonin receptor 0.006 0.0272 0.0405
Brugia malayi Trypsin-like protease protein 5 0.0021 0.0035 0.0051
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0014
Trypanosoma cruzi pyruvate kinase 2, putative 0.0071 0.0337 0.1885
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.006 0.0272 0.0271
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0051
Onchocerca volvulus 0.006 0.0272 0.0405
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0064 0.0094
Trichomonas vaginalis alpha-amylase, putative 0.0039 0.0145 0.0205
Onchocerca volvulus 0.006 0.0272 0.0405
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0045 0.0178 0.0177
Echinococcus granulosus neuropeptide FF receptor 2 0.006 0.0272 0.0405
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0026 0.0065 0.0096
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0446 0.2616 0.5521
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0034 0.0111 0.0165
Loa Loa (eye worm) prolyl oligopeptidase 0.0209 0.1177 0.1759
Loa Loa (eye worm) pyruvate kinase 0.0071 0.0337 0.0502
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.006 0.0272 0.0313
Trichomonas vaginalis alpha-glucosidase, putative 0.0114 0.06 0.0886
Schistosoma mansoni hypothetical protein 0.0034 0.0111 0.0128
Loa Loa (eye worm) hypothetical protein 0.018 0.0997 0.149
Toxoplasma gondii alpha amylase, catalytic domain-containing protein 0.0017 0.0013 0.0185
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0042 0.0163 0.0188
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0053 0.0227 0.0328
Brugia malayi hypothetical protein 0.006 0.0272 0.0405
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0017 0.0008 0.0007
Schistosoma mansoni lamin 0.0055 0.0243 0.028
Schistosoma mansoni biogenic amine receptor 0.006 0.0272 0.0313
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0111 0.0111
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Brugia malayi bHLH-PAS transcription factor 0.0074 0.0355 0.053
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0094 0.048 0.0717
Trichomonas vaginalis alpha-glucosidase, putative 0.0114 0.06 0.0886
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0065 0.0085
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0029 0.0412
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0128 0.0686 0.0792
Echinococcus multilocularis pyruvate kinase 0.0036 0.0128 0.0127
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0533 0.3139 0.3627
Brugia malayi hypothetical protein 0.0021 0.0036 0.0053
Echinococcus multilocularis serotonin receptor 0.018 0.0997 0.0996
Echinococcus granulosus dro:myosuppressin receptor 0.006 0.0272 0.0405
Echinococcus multilocularis biogenic amine (5HT) receptor 0.006 0.0272 0.0271
Echinococcus multilocularis tissue type plasminogen activator 0.0101 0.0517 0.0517
Brugia malayi prolyl oligopeptidase family protein 0.0017 0.0008 0.0011
Brugia malayi MH2 domain containing protein 0.0026 0.0064 0.0094
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0071 0.1235
Trypanosoma brucei glycosyl hydrolase-like protein 0.0042 0.0165 0.0902
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0021 0.0035 0.004
Brugia malayi MH2 domain containing protein 0.0026 0.0064 0.0094
Trichomonas vaginalis amylase, putative 0.0039 0.0145 0.0205
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.0227 0.0328
Echinococcus granulosus growth factor receptor bound protein 2 0.0152 0.083 0.124
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0021 0.0035 0.0051
Echinococcus granulosus glycogen phosphorylase 0.1118 0.6687 1
Toxoplasma gondii P-type ATPase4, putative 0.0053 0.0227 0.3249
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.078 0.4429
Echinococcus multilocularis sodium channel protein 0.0078 0.0381 0.038
Toxoplasma gondii isocitrate dehydrogenase 0.0034 0.0111 0.1596
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.007 0.0334 0.1871
Leishmania major calcium-translocating P-type ATPase 0.0053 0.0227 0.1255
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0111 0.0584 0.1218
Loa Loa (eye worm) hypothetical protein 0.0441 0.2586 0.3866
Schistosoma mansoni smad 0.0026 0.0064 0.0073
Echinococcus multilocularis g protein coupled receptor 0.006 0.0272 0.0271
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0458 0.0528
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus Basic leucine zipper bZIP transcription factor 0.0082 0.0407 0.0608
Entamoeba histolytica glycogen phosphorylase, putative 0.0483 0.2839 0.4238
Echinococcus multilocularis pyruvate kinase 0.0056 0.0246 0.0246
Schistosoma mansoni growth hormone secretagogue receptor 0.006 0.0272 0.0313
Brugia malayi Ets-domain containing protein 0.0077 0.0377 0.0563
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.003 0.0087 0.0129
Brugia malayi Glycosyl hydrolases family 31 protein 0.0042 0.0165 0.0246
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0034 0.0111 0.2029
Brugia malayi nuclear receptor NHR-88 0.0094 0.048 0.0717
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0094 0.048 0.0717
Echinococcus granulosus jun protein 0.0082 0.0407 0.0608
Onchocerca volvulus 0.0021 0.0035 0.0051
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.007 0.0334 0.1871
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0087 0.0437 0.0653
Echinococcus granulosus aryl hydrocarbon receptor 0.0026 0.0065 0.0096
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus beta LACTamase domain containing family member 0.007 0.0331 0.0494
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0065 0.0085
Brugia malayi Tachykinin-like peptides receptor 99D 0.006 0.0272 0.0405
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0272 0.0271
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0017 0.0008 0.0117
Echinococcus granulosus glucan 14 alpha branching enzyme 1 0.0017 0.0013 0.0018
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0144 0.078 0.4429
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0022 0.0412
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0094 0.048 0.0717
Loa Loa (eye worm) hypothetical protein 0.0054 0.0237 0.0353
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.004 0.0148 0.0296
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0034 0.0111 0.0111
Echinococcus granulosus intermediate filament protein 0.0055 0.0243 0.0362
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0094 0.048 0.0554
Echinococcus granulosus nervana 2 0.0533 0.3139 0.4693
Trichomonas vaginalis maltase-glucoamylase, putative 0.0114 0.06 0.0886
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0111 0.0593
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.005 0.021 0.0313
Schistosoma mansoni pyruvate kinase 0.0036 0.0128 0.0147
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0182 0.027
Loa Loa (eye worm) hypothetical protein 0.0027 0.0071 0.0105
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0023 0.0047 0.0069
Brugia malayi G protein-coupled receptor 0.006 0.0272 0.0405
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0021 0.0035 0.004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0011
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0483 0.2839 0.5993
Brugia malayi hypothetical protein 0.013 0.0697 0.1041
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0036 0.0124 0.2376
Trypanosoma cruzi P-type H+-ATPase, putative 0.0023 0.0047 0.0223
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0147 0.0799 0.1194
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0017 0.0008 0.0009
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Schistosoma mansoni hypothetical protein 0.006 0.0272 0.0313
Leishmania major hypothetical protein, conserved 0.0101 0.0517 0.292
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0279 0.0321
Echinococcus granulosus neuropeptide Y receptor 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0094 0.048 0.0717
Onchocerca volvulus 0.0021 0.0035 0.0051
Schistosoma mansoni biogenic amine (5HT) receptor 0.006 0.0272 0.0313
Echinococcus granulosus g protein coupled receptor 0.006 0.0272 0.0405
Entamoeba histolytica hypothetical protein 0.0075 0.0361 0.0528
Loa Loa (eye worm) calcium ATPase 0.003 0.0087 0.013
Leishmania major calcium motive p-type ATPase, putative 0.0042 0.0163 0.0889
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0021 0.0035 0.0034
Onchocerca volvulus 0.0121 0.0644 0.0962
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0042 0.0163 0.0232
Mycobacterium tuberculosis Probable multifunctional mycocerosic acid synthase membrane-associated Mas 0.003 0.0089 0.0179
Echinococcus multilocularis sodium:potassium transporting ATPase subunit 0.0533 0.3139 0.3139
Schistosoma mansoni cation-transporting ATPase 0.0017 0.0008 0.0009
Loa Loa (eye worm) hypothetical protein 0.0106 0.0552 0.0824
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0022 0.0032
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.007 0.0331 0.0494
Schistosoma mansoni glycogen phosphorylase 0.1118 0.6687 0.7727
Echinococcus granulosus fmrfamide receptor 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0017 0.001 0.0014
Toxoplasma gondii beta-ketoacyl synthase, N-terminal domain-containing protein 0.0018 0.0019 0.0266
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0051
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.006 0.0272 0.0271
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0035 0.0117 0.0117
Giardia lamblia 1,4-alpha-glucan branching enzyme 0.0017 0.0013 0.0007
Echinococcus multilocularis inositol monophosphatase 1 0.004 0.0148 0.0147
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0167 0.091
Echinococcus multilocularis beta LACTamase domain containing family member 0.007 0.0331 0.0331
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.003 0.0087 0.0119
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0002 0.0001
Mycobacterium leprae Probable polyketide synthase Pks1 0.003 0.0089 0.0172
Loa Loa (eye worm) hypothetical protein 0.0094 0.048 0.0717
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0042 0.0163 0.0162
Leishmania major P-type ATPase, putative 0.0042 0.0163 0.0889
Schistosoma mansoni ATPase 0.0053 0.0227 0.0261
Mycobacterium tuberculosis Polyketide synthase Pks13 0.0042 0.0163 0.0335
Brugia malayi hypothetical protein 0.006 0.0272 0.0405
Schistosoma mansoni pyruvate kinase 0.0071 0.0337 0.0388
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0279 0.0321
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0094 0.048 0.0554
Echinococcus granulosus prolyl endopeptidase 0.0017 0.0008 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0052 0.0093
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0036 0.0124 0.1772
Echinococcus multilocularis fmrfamide receptor 0.006 0.0272 0.0271
Echinococcus granulosus tar DNA binding protein 0.0061 0.0279 0.0416
Echinococcus multilocularis voltage dependent calcium channel 0.0085 0.0425 0.0424
Onchocerca volvulus 0.0055 0.0243 0.0362
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0021 0.0035 0.004
Loa Loa (eye worm) hypothetical protein 0.0076 0.0367 0.0548
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0075 0.0361 0.0539
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0272 0.0271
Brugia malayi Trypsin family protein 0.0121 0.0644 0.0962
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0017 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.007 0.0331 0.0494
Loa Loa (eye worm) hypothetical protein 0.005 0.021 0.0313
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0018
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0178 0.0265
Brugia malayi hypothetical protein 0.0021 0.0036 0.0053
Brugia malayi Niemann-Pick C1 protein precursor 0.0105 0.0546 0.0815
Echinococcus multilocularis cation transporting atpase worm 0.0017 0.0008 0.0008
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0094 0.048 0.0554
Onchocerca volvulus Bile acid receptor homolog 0.0094 0.048 0.0717
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0035 0.0123 0.0243
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0046 0.0068
Schistosoma mansoni amine GPCR 0.006 0.0272 0.0313
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0071 0.0361
Leishmania major P-type H -ATPase, putative 0.0033 0.0111 0.0589
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0272 0.0313
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Loa Loa (eye worm) hypothetical protein 0.0094 0.048 0.0717
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0052 0.0222 0.0331
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0035 0.0117 0.0175
Schistosoma mansoni hypothetical protein 0.0021 0.0035 0.004
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0331 0.0484
Plasmodium vivax copper-transporting ATPase, putative 0.0017 0.0008 0.014
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0114 0.06 0.0886
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0034 0.0111 0.0111
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0042 0.0163 0.0243
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0121 0.0644 0.0743
Trichomonas vaginalis alpha-glucosidase, putative 0.0114 0.06 0.0886
Trypanosoma cruzi hypothetical protein, conserved 0.0114 0.06 0.3393
Echinococcus multilocularis G-protein coupled receptor, putative 0.006 0.0272 0.0271
Onchocerca volvulus Pyruvate kinase homolog 0.0071 0.0337 0.0502
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0296 0.0442
Echinococcus granulosus somatostatin receptor 0.006 0.0272 0.0405
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.006 0.0272 0.0313
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.001 0.001
Trypanosoma cruzi hypothetical protein, conserved 0.007 0.0331 0.1854
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0042 0.0163 0.0243
Echinococcus granulosus g protein coupled receptor 0.006 0.0272 0.0405
Trichomonas vaginalis pyruvate kinase, putative 0.0071 0.0337 0.0492
Mycobacterium tuberculosis Probable polyketide synthase Pks7 0.003 0.0089 0.0179
Schistosoma mansoni nuclear receptor 0.0045 0.0178 0.0204
Loa Loa (eye worm) pyruvate kinase-PB 0.0049 0.0207 0.0308
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0065 0.0325
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0053 0.0227 0.0328
Toxoplasma gondii hypothetical protein 0.0087 0.0437 0.6259
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0094 0.048 0.0717
Trichomonas vaginalis pyruvate kinase, putative 0.0071 0.0337 0.0492
Schistosoma mansoni hypothetical protein 0.0034 0.0111 0.0128
Loa Loa (eye worm) beta-lactamase 0.007 0.0331 0.0494
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0051
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0021 0.0035 0.004
Brugia malayi steroid hormone receptor 0.0094 0.048 0.0717
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0114 0.06 0.8586
Loa Loa (eye worm) hypothetical protein 0.0533 0.3139 0.4693
Toxoplasma gondii ABC1 family protein 0.007 0.0331 0.4746
Brugia malayi hypothetical protein 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0022
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0085 0.0425 0.049
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Loa Loa (eye worm) follicle stimulating hormone receptor 0.006 0.0272 0.0405
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0045 0.0178 0.0265
Trichomonas vaginalis alpha-amylase, putative 0.0039 0.0145 0.0205
Loa Loa (eye worm) hypothetical protein 0.0121 0.0644 0.0962
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.1751 1
Brugia malayi acetyltransferase, GNAT family protein 0.0121 0.0643 0.096
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0094 0.048 0.0717
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0094 0.048 0.0479
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0327 0.1894 0.2188
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0036 0.0124 0.1772
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0698 0.0806
Mycobacterium tuberculosis Probable thioesterase TesA 0.0024 0.005 0.0096
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0272 0.0313
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0178 0.0204
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0065 0.0325
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0178 0.0265
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0026 0.0065 0.0096
Loa Loa (eye worm) hypothetical protein 0.008 0.0394 0.0588
Schistosoma mansoni aldehyde dehydrogenase 0.013 0.0698 0.0806
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0064 0.0296 0.1653
Echinococcus multilocularis Ankyrin 0.0015 0.0002 0.0001
Mycobacterium ulcerans polyketide synthase Pks13 0.0042 0.0163 0.0329
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0094 0.048 0.0717
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0017 0.0019
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0077 0.0377 0.0563
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0165 0.0235
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0085 0.0425 0.0424
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.007 0.0334 0.1871
Mycobacterium tuberculosis 1,4-alpha-glucan branching enzyme GlgB (glycogen branching enzyme) 0.0017 0.0013 0.0017
Echinococcus multilocularis musashi 0.0055 0.0243 0.0242
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.006 0.0272 0.0405
Echinococcus granulosus Ankyrin 0.0015 0.0002 0.0001
Schistosoma mansoni hypothetical protein 0.0044 0.0172 0.0197
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0042 0.0163 0.0188
Trypanosoma brucei pteridine reductase 1 0.0189 0.1056 0.6009
Echinococcus granulosus enteropeptidase 0.0021 0.0035 0.0051
Loa Loa (eye worm) hypothetical protein 0.0339 0.1965 0.2938
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0165 0.0235
Echinococcus granulosus sodium channel protein 0.0046 0.0189 0.0281
Echinococcus granulosus hypothetical protein 0.0737 0.438 0.6549
Leishmania major protein kinase, putative 0.0026 0.0065 0.0325
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0331 0.0484
Onchocerca volvulus 0.0056 0.0248 0.037
Trypanosoma cruzi cation-transporting ATPase, putative 0.0017 0.0008 0.0001
Echinococcus granulosus biogenic amine 5HT receptor 0.006 0.0272 0.0405
Toxoplasma gondii pyruvate kinase PyK1 0.0071 0.0337 0.4821
Schistosoma mansoni gabp alpha 0.0077 0.0377 0.0435
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.0227 0.0328
Brugia malayi hypothetical protein 0.005 0.021 0.0313
Echinococcus granulosus bloom syndrome protein 0.0023 0.0046 0.0068
Brugia malayi putative neuropeptide receptor NPR1 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Toxoplasma gondii type I fatty acid synthase, putative 0.0031 0.0095 0.1364
Schistosoma mansoni nuclear hormone receptor 0.0094 0.048 0.0554
Brugia malayi hypothetical protein 0.0335 0.1938 0.2896
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0107 0.0556 0.0642
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Trichomonas vaginalis alpha-amylase, putative 0.0035 0.0119 0.0166
Echinococcus multilocularis jun protein 0.0082 0.0407 0.0407
Schistosoma mansoni alpha-glucosidase 0.0443 0.2592 0.2995
Schistosoma mansoni hypothetical protein 0.0044 0.0172 0.0197
Schistosoma mansoni ap endonuclease 0.0019 0.0022 0.0025
Mycobacterium ulcerans hypothetical protein 0.0021 0.0035 0.0057
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0094 0.048 0.0717
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0022
Trypanosoma brucei calcium-transporting ATPase, putative 0.0025 0.0061 0.0301
Trypanosoma cruzi P-type H+-ATPase, putative 0.0033 0.0111 0.0589
Loa Loa (eye worm) hypothetical protein 0.0095 0.0483 0.0721
Mycobacterium ulcerans polyketide synthase 0.003 0.0089 0.0172
Loa Loa (eye worm) hypothetical protein 0.0105 0.0546 0.0815
Echinococcus multilocularis pyruvate kinase 0.0071 0.0337 0.0336
Brugia malayi Intermediate filament tail domain containing protein 0.0055 0.0243 0.0362
Brugia malayi hypothetical protein 0.016 0.0878 0.1312
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0182 0.0181
Trypanosoma cruzi calcium-transporting ATPase, putative 0.0025 0.0061 0.0301
Echinococcus granulosus lamin 0.0055 0.0243 0.0362
Echinococcus granulosus Dipeptidyl peptidase 9 0.007 0.0334 0.0499
Loa Loa (eye worm) hypothetical protein 0.0018 0.0018 0.0026
Brugia malayi intermediate filament protein 0.0055 0.0243 0.0362
Trichomonas vaginalis guanylate cyclase, putative 0.0026 0.0065 0.0085
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0036 0.0546
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0051
Brugia malayi MH1 domain containing protein 0.0026 0.0064 0.0094
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0053 0.0227 0.0328
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus allatostatin A receptor 0.006 0.0272 0.0405
Schistosoma mansoni thyroid hormone receptor 0.0094 0.048 0.0554
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0052 0.0093
Trichomonas vaginalis glutaminase, putative 0.0584 0.3448 0.5151
Leishmania major copper-transporting ATPase-like protein, putative 0.0017 0.0008 0.0001
Brugia malayi calcium ATPase 0.0019 0.0024 0.0034
Onchocerca volvulus 0.007 0.0331 0.0494
Echinococcus multilocularis lamin dm0 0.0055 0.0243 0.0242
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.006 0.0272 0.0271
Plasmodium falciparum pyruvate kinase 2 0.0036 0.0128 0.2351
Echinococcus granulosus histone lysine methyltransferase setb 0.0091 0.0458 0.0683
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0059 0.0267 0.0398
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.001 0.001
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0036 0.0053
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0064 0.0094
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.006 0.0272 0.0405
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0085 0.0425 0.0424
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0017 0.0008 0.0119
Brugia malayi glutaminase DH11.1 0.0584 0.3448 0.5156
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0022
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus Na:K ATPase alpha subunit 0.0118 0.0623 0.093
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0094 0.048 0.0717
Brugia malayi E1-E2 ATPase family protein 0.0033 0.0111 0.0165
Leishmania major pyruvate kinase 0.0071 0.0337 0.1885
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0094 0.048 0.0717
Brugia malayi putative neuropeptide receptor 0.006 0.0272 0.0405
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.007 0.0331 0.0691
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0021 0.0035 0.0034
Echinococcus multilocularis dro:myosuppressin receptor 0.006 0.0272 0.0271
Echinococcus multilocularis neuropeptides capa receptor 0.006 0.0272 0.0271
Onchocerca volvulus 0.0026 0.0065 0.0096
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0023 0.0047 0.0058
Mycobacterium tuberculosis Probable lipase LipD 0.007 0.0331 0.0691
Echinococcus multilocularis nuclear receptor nhr 48 0.0045 0.0178 0.0177
Trichomonas vaginalis alpha-amylase, putative 0.0039 0.0145 0.0205
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0071 0.0361
Echinococcus granulosus Mastin 0.0021 0.0035 0.0051
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0053 0.0227 0.0226
Echinococcus granulosus RUN 0.0021 0.0036 0.0053
Echinococcus multilocularis flap endonuclease 1 0.0028 0.0076 0.0076
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0036 0.0053
Echinococcus granulosus survival motor neuron protein 1 0.0721 0.4279 0.6398
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0272 0.0405
Trichomonas vaginalis flap endonuclease-1, putative 0.0028 0.0076 0.0102
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0052 0.0253
Echinococcus multilocularis neuropeptide receptor 0.006 0.0272 0.0271
Giardia lamblia Pyruvate kinase 0.0036 0.0128 0.0179
Echinococcus multilocularis Niemann Pick C1 protein 0.015 0.082 0.0819
Loa Loa (eye worm) hypothetical protein 0.005 0.021 0.0313
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0222 0.0256
Schistosoma mansoni hypothetical protein 0.0044 0.0172 0.0197
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0118 0.0623 0.092
Schistosoma mansoni hypothetical protein 0.0044 0.0172 0.0197
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Schistosoma mansoni type V p-type atpase isoform 0.0017 0.0008 0.0009
Echinococcus multilocularis Dipeptidyl peptidase 9 0.007 0.0334 0.0334
Plasmodium vivax pyruvate kinase, putative 0.0071 0.0337 0.6502
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.006 0.0272 0.0405
Loa Loa (eye worm) fli-1 protein 0.0235 0.1333 0.1993
Trypanosoma brucei P-type H+-ATPase, putative 0.0033 0.0111 0.0589
Schistosoma mansoni opsin-like receptor 0.006 0.0272 0.0313
Brugia malayi follicle stimulating hormone receptor 0.006 0.0272 0.0405
Onchocerca volvulus 0.0024 0.0052 0.0077
Mycobacterium tuberculosis Conserved protein 0.007 0.0331 0.0691
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0034 0.0111 0.2138
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.006 0.0272 0.0313
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Mycobacterium tuberculosis Probable polyketide synthase Pks5 0.0027 0.0073 0.0145
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0053 0.0227 0.0463
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0046 0.0045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0272 0.0313
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Schistosoma mansoni survival motor neuron protein 0.0147 0.0799 0.0923
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Brugia malayi hypothetical protein 0.006 0.0272 0.0405
Echinococcus multilocularis somatostatin receptor 0.006 0.0272 0.0271
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0026 0.0065 0.0085
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0114 0.06 0.0896
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0053 0.0227 0.0328
Echinococcus granulosus geminin 0.0854 0.509 0.7611
Loa Loa (eye worm) inositol-1 0.004 0.0148 0.022
Loa Loa (eye worm) TYRA-2 protein 0.006 0.0272 0.0405
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0022 0.003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0272 0.0313
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0021 0.0035 0.0051
Brugia malayi Serotonin/octopamine receptor family protein 7 0.035 0.2032 0.3038
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0279 0.0321
Trichomonas vaginalis inositol monophosphatase, putative 0.004 0.0148 0.0209
Brugia malayi Trypsin family protein 0.0021 0.0035 0.0051
Onchocerca volvulus 0.0327 0.1894 0.2831
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.007 0.0334 0.1871
Echinococcus multilocularis FTZ F1 alpha 0.0094 0.048 0.0479
Brugia malayi Inositol-1 0.004 0.0148 0.022
Onchocerca volvulus 0.0021 0.0035 0.0051
Onchocerca volvulus 0.006 0.0272 0.0405
Giardia lamblia Fructose-bisphosphate aldolase 0.0318 0.1838 0.274
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1838 0.274
Chlamydia trachomatis 1,4-alpha-glucan branching enzyme 0.0017 0.0013 0.0007
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0117 0.1682
Entamoeba histolytica Flap nuclease, putative 0.0028 0.0076 0.0102
Echinococcus granulosus nuclear factor of activated T cells 5 0.0079 0.0385 0.0575
Trypanosoma brucei glucosidase, putative 0.0114 0.06 0.3393
Loa Loa (eye worm) E1-E2 ATPase 0.0033 0.0111 0.0165
Loa Loa (eye worm) hypothetical protein 0.005 0.021 0.0313
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0064 0.0094
Brugia malayi beta-lactamase 0.007 0.0331 0.0494
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0117 0.2147
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Loa Loa (eye worm) hypothetical protein 0.0055 0.0243 0.0363
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0022 0.0077
Schistosoma mansoni biogenic amine receptor 0.006 0.0272 0.0313
Loa Loa (eye worm) trypsin family protein 0.0021 0.0035 0.0051
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.006 0.0272 0.0405
Schistosoma mansoni opsin-like receptor 0.006 0.0272 0.0313
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0331 0.0382
Leishmania major glycosyl hydrolase-like protein 0.0042 0.0165 0.0902
Schistosoma mansoni transcription factor LCR-F1 0.0075 0.0361 0.0416
Echinococcus multilocularis orexin receptor type 2 0.006 0.0272 0.0271
Plasmodium falciparum cysteine repeat modular protein 1 0.0101 0.0517 1
Echinococcus multilocularis lysosomal alpha glucosidase 0.0514 0.3027 0.3026
Brugia malayi 1,4-alpha-glucan branching enzyme 0.0017 0.0013 0.0018
Brugia malayi nuclear hormone receptor 0.0045 0.0178 0.0265
Toxoplasma gondii transporter, cation channel family protein 0.0022 0.0044 0.0626
Leishmania major calcium-transporting ATPase, putative 0.0042 0.0163 0.0889
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0052 0.0093
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0094 0.048 0.0717
Echinococcus multilocularis transfer RNA-Lys 0.0074 0.0355 0.0355
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0035 0.0117 0.2254
Echinococcus multilocularis calcium transporting atpase 0.0042 0.0163 0.0162
Onchocerca volvulus 0.0053 0.0228 0.034
Loa Loa (eye worm) hypothetical protein 0.0128 0.0686 0.1025
Brugia malayi Protein kinase domain containing protein 0.0101 0.0517 0.0772
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0054 0.0236 0.1307
Plasmodium falciparum calcium-transporting ATPase 0.0042 0.0163 0.3044
Echinococcus granulosus transmembrane protease serine 3 0.0021 0.0035 0.0051
Loa Loa (eye worm) hypothetical protein 0.0721 0.4279 0.6398
Echinococcus multilocularis neuropeptide s receptor 0.006 0.0272 0.0271
Plasmodium vivax hypothetical protein, conserved 0.007 0.0331 0.64
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0272 0.0271
Brugia malayi hypothetical protein 0.0075 0.0361 0.0539
Schistosoma mansoni hypothetical protein 0.0075 0.0361 0.0416
Schistosoma mansoni smad1 5 8 and 0.0026 0.0064 0.0073
Trichomonas vaginalis glycogen phosphorylase, putative 0.1118 0.6687 1
Echinococcus granulosus 7tm_1 domain containing protein 0.006 0.0272 0.0405
Brugia malayi TAR-binding protein 0.0061 0.0279 0.0416
Schistosoma mansoni transmemberane protein 0.0533 0.3139 0.3627
Brugia malayi nuclear hormone receptor family member nhr-6 0.0045 0.0178 0.0265
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0178 0.0177
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0026 0.0065 0.0085
Leishmania major protein kinase, putative 0.0026 0.0065 0.0325
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0094 0.048 0.0479
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0046 0.0057
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0155 0.0851 0.1783
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0017 0.0008 0.0007
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.006 0.0272 0.0405
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0085 0.0425 0.0634
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0094 0.048 0.0717
Echinococcus granulosus sodium:potassium transporting ATPase subunit 0.0533 0.3139 0.4693
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0034 0.0111 0.0165
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0022 0.0021
Schistosoma mansoni biogenic amine receptor 0.006 0.0272 0.0313
Entamoeba histolytica myo-inositol monophosphatase, putative 0.004 0.0148 0.0209
Loa Loa (eye worm) hypothetical protein 0.0094 0.048 0.0717
Mycobacterium ulcerans glutaminase 0.0584 0.3448 0.728
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.006 0.0272 0.0405
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0028 0.0079 0.0149
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0458 0.0528
Loa Loa (eye worm) nuclear receptor NHR-67 0.0045 0.0178 0.0265
Brugia malayi Serotonin receptor 0.0511 0.301 0.4501
Loa Loa (eye worm) hypothetical protein 0.0441 0.2586 0.3866
Schistosoma mansoni peptide (allatostatin)-like receptor 0.006 0.0272 0.0313
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0053 0.0227 0.0328
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0796 0.4734 1
Echinococcus granulosus nervana 2 0.0533 0.3139 0.4693
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsB 0.0023 0.0045 0.0079
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0118 0.0623 0.0719
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0045 0.0178 0.0265
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0533 0.3139 0.4693
Schistosoma mansoni family A2 unassigned peptidase (A02 family) 0.0262 0.1498 0.173
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0272 0.0405
Brugia malayi nuclear hormone receptor family member odr-7 0.0045 0.0178 0.0265
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1838 0.274
Entamoeba histolytica glycogen phosphorylase, putative 0.1118 0.6687 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0045 0.0178 0.0204
Onchocerca volvulus Glycogen phosphorylase homolog 0.1118 0.6687 1
Loa Loa (eye worm) glutaminase 0.0584 0.3448 0.5156
Mycobacterium tuberculosis Probable polyketide synthase Pks1 0.002 0.0031 0.0054
Entamoeba histolytica acetyltransferase, GNAT family 0.0033 0.0106 0.0146
Schistosoma mansoni hypothetical protein 0.006 0.0272 0.0313
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0053 0.0227 0.1255
Entamoeba histolytica alpha-amylase family protein 0.0039 0.0145 0.0205
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0026 0.0065 0.0325
Loa Loa (eye worm) hypothetical protein 0.0026 0.0063 0.0093
Onchocerca volvulus 0.0021 0.0035 0.0051
Loa Loa (eye worm) runx1 0.0055 0.0244 0.0363
Mycobacterium tuberculosis Probable conserved lipoprotein 0.007 0.0331 0.0691
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0222 0.0221
Schistosoma mansoni voltage-gated cation channel 0.0085 0.0425 0.049
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0064 0.0296 0.0442
Loa Loa (eye worm) hypothetical protein 0.0073 0.0348 0.0519
Schistosoma mansoni sodium/potassium-dependent atpase beta subunit 0.0533 0.3139 0.3627
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0028 0.0076 0.0392
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0022 0.0022
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0036 0.0035
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0167 0.091
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0165 0.0235
Echinococcus granulosus Smad4 0.0026 0.0064 0.0094
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0034 0.0111 0.0111
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0094 0.048 0.0717
Loa Loa (eye worm) hypothetical protein 0.0026 0.0065 0.0096
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0065 0.0085
Entamoeba histolytica 1,4-alpha-glucan branching enzyme, putative 0.0017 0.0013 0.0007
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus Niemann Pick C1 protein 0.015 0.082 0.1225
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0272 0.0271
Loa Loa (eye worm) hypothetical protein 0.0335 0.1938 0.2896
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0272 0.0313
Loa Loa (eye worm) hypothetical protein 0.0034 0.0111 0.0165
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0167 0.091
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0053 0.0227 0.1255
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0021 0.0037 0.0055
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0017 0.0008 0.0007
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0094 0.048 0.0554
Echinococcus granulosus histone acetyltransferase KAT2B 0.0118 0.0622 0.0929
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0209 0.1177 0.1759
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0034 0.0111 0.0225
Onchocerca volvulus 0.0147 0.0799 0.1194
Onchocerca volvulus 0.016 0.0878 0.1312
Brugia malayi sulfakinin receptor protein 0.006 0.0272 0.0405
Echinococcus granulosus pyruvate kinase 0.0036 0.0128 0.019
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0318 0.1838 0.274
Brugia malayi GnHR receptor homolog 0.006 0.0272 0.0405
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0165 0.0235
Echinococcus multilocularis nervana 2 0.0327 0.1894 0.1893
Trichomonas vaginalis conserved hypothetical protein 0.0026 0.0065 0.0085
Trichomonas vaginalis sucrase-isomaltase, putative 0.0114 0.06 0.0886
Echinococcus multilocularis acylamino acid releasing enzyme 0.0017 0.0008 0.0007
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0053 0.0227 0.1255
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0071 0.0337 0.0702
Trichomonas vaginalis myo inositol monophosphatase, putative 0.004 0.0148 0.0209
Brugia malayi hypothetical protein 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Loa Loa (eye worm) hypothetical protein 0.0055 0.0243 0.0362
Schistosoma mansoni microtubule-associated protein tau 0.0688 0.4081 0.4715
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0022 0.0082
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0025 0.0061 0.009
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0052 0.0253
Loa Loa (eye worm) hypothetical protein 0.0022 0.0044 0.0064
Loa Loa (eye worm) hypothetical protein 0.0045 0.0182 0.027
Mycobacterium leprae Polyketide synthase Pks13 0.0042 0.0163 0.0329
Loa Loa (eye worm) neuropeptide F receptor 0.006 0.0272 0.0405
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0272 0.0405
Leishmania major hypothetical protein, conserved 0.0027 0.0071 0.0361
Brugia malayi conserved hypotetical protein 0.0045 0.0178 0.0265
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus microtubule associated protein 2 0.0688 0.4081 0.6101
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0064 0.0296 0.0296
Leishmania major pyruvate kinase 0.0071 0.0337 0.1885
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0105 0.0546 0.0805
Plasmodium falciparum copper-transporting ATPase 0.0017 0.0008 0.0004
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0533 0.3139 0.3139
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Chlamydia trachomatis glycogen phosphorylase 0.1118 0.6687 1
Schistosoma mansoni hypothetical protein 0.0101 0.0517 0.0597
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0042 0.0163 0.0243
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0094 0.048 0.0717
Mycobacterium ulcerans beta-lactamase 0.007 0.0331 0.0684
Schistosoma mansoni amine GPCR 0.0385 0.2244 0.2592
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0111 0.0593
Echinococcus multilocularis cation transporting ATPase 13A3 0.0017 0.0008 0.0008
Schistosoma mansoni lipoxygenase 0.0059 0.0267 0.0308
Brugia malayi Doublecortin family protein 0.0021 0.0036 0.0053
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0272 0.0271
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0028 0.0076 0.1094
Echinococcus granulosus biogenic amine 5HT receptor 0.018 0.0997 0.149
Brugia malayi Fli-1 protein 0.0235 0.1333 0.1993
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0059 0.0267 0.0266
Brugia malayi hypothetical protein 0.006 0.0272 0.0405
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0094 0.048 0.0479
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.003 0.0089 0.0172
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0061 0.0279 0.0416
Trichomonas vaginalis alpha-glucosidase, putative 0.0114 0.06 0.0886
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0052 0.0093
Echinococcus granulosus calcium transporting atpase 0.0042 0.0163 0.0243
Onchocerca volvulus 0.0021 0.0036 0.0053
Schistosoma mansoni coup transcription factor 0.0094 0.048 0.0554
Echinococcus granulosus neuropeptide s receptor 0.006 0.0272 0.0405
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0052 0.0077
Loa Loa (eye worm) DR-78 0.0045 0.0178 0.0265
Loa Loa (eye worm) Smad1 0.0026 0.0064 0.0094
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsE 0.0019 0.0021 0.0027
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0209 0.1177 0.1359
Echinococcus granulosus cation transporting ATPase 13A3 0.0017 0.0008 0.0011
Echinococcus granulosus lamin dm0 0.0055 0.0243 0.0362
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0001
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0026 0.0065 0.0085
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0327 0.1894 0.2831
Toxoplasma gondii 1,4-alpha-glucan-branching enzyme 0.0017 0.0013 0.0185
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Loa Loa (eye worm) hypothetical protein 0.0024 0.0052 0.0077
Brugia malayi G protein-coupled receptor F59B2.13 0.006 0.0272 0.0405
Onchocerca volvulus 0.006 0.0272 0.0405
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0017 0.0008 0.0009
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0106 0.0552 0.0824
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0094 0.048 0.0717
Schistosoma mansoni cellular tumor antigen P53 0.0053 0.0228 0.0263
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0034 0.0111 0.0111
Schistosoma mansoni neuropeptide receptor 0.006 0.0272 0.0313
Echinococcus granulosus FTZ F1 alpha 0.0094 0.048 0.0717
Onchocerca volvulus 0.006 0.0272 0.0405
Loa Loa (eye worm) G-protein coupled receptor 0.006 0.0272 0.0405
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0034 0.0111 0.0165
Loa Loa (eye worm) hypothetical protein 0.0016 0.0003 0.0004
Plasmodium falciparum histone acetyltransferase GCN5 0.0033 0.0106 0.1917
Onchocerca volvulus 0.0533 0.3139 0.4693
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0028 0.0079 0.0156
Trichomonas vaginalis bromodomain-containing protein, putative 0.0036 0.0124 0.0173
Brugia malayi Kringle domain containing protein 0.0101 0.0517 0.0772
Loa Loa (eye worm) calcium channel 0.0085 0.0425 0.0634
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.013 0.0698 0.0698
Entamoeba histolytica hypothetical protein 0.0075 0.0361 0.0528
Loa Loa (eye worm) neuropeptide F receptor 0.006 0.0272 0.0405
Schistosoma mansoni hypothetical protein 0.0021 0.0035 0.004
Onchocerca volvulus 0.006 0.0272 0.0405
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0053 0.0227 0.3249
Schistosoma mansoni Smad4 0.0026 0.0064 0.0073
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0045 0.0178 0.0265
Echinococcus granulosus voltage dependent calcium channel 0.0022 0.0044 0.0064
Plasmodium falciparum ataxin-2 like protein, putative 0.0027 0.0071 0.1235
Echinococcus granulosus ecdysone induced protein 78C 0.0094 0.048 0.0717
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1838 0.274
Echinococcus multilocularis neuropeptide receptor 0.006 0.0272 0.0271
Onchocerca volvulus Huntingtin homolog 0.0252 0.1435 0.2144
Mycobacterium tuberculosis Probable hydrolase 0.007 0.0331 0.0691
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0182 0.027
Brugia malayi photoreceptor-specific nuclear receptor 0.0094 0.048 0.0717
Mycobacterium leprae conserved hypothetical protein 0.007 0.0331 0.0684
Loa Loa (eye worm) hypothetical protein 0.0024 0.0052 0.0077
Brugia malayi RNA recognition motif domain containing protein 0.0061 0.0279 0.0416
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0036 0.0124 0.0253
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0042 0.0163 0.0162
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus alpha 1A adrenergic receptor 0.006 0.0272 0.0405
Mycobacterium leprae Probable pyruvate kinase PykA 0.0071 0.0337 0.0695
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0023 0.0047 0.0673
Toxoplasma gondii glycosyltransferase 0.0017 0.0013 0.0185
Schistosoma mansoni cation-transporting atpase worm 0.0017 0.0008 0.0009
Echinococcus multilocularis nervana 2 0.0327 0.1894 0.1893
Loa Loa (eye worm) hypothetical protein 0.0094 0.048 0.0717
Mycobacterium tuberculosis Probable membrane bound polyketide synthase Pks6 0.0042 0.0163 0.0335
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0114 0.06 0.0886
Loa Loa (eye worm) transcription factor SMAD2 0.0378 0.2199 0.3288
Entamoeba histolytica hypothetical protein 0.0075 0.0361 0.0528
Toxoplasma gondii pyruvate kinase PyKII 0.0036 0.0128 0.183
Echinococcus multilocularis tumor protein p63 0.0361 0.2099 0.2098
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0222 0.0331
Brugia malayi beta-lactamase family protein 0.007 0.0331 0.0494
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0209 0.1177 0.1176
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0045 0.0178 0.0265
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0053 0.0227 0.0338
Loa Loa (eye worm) hypothetical protein 0.005 0.021 0.0313
Brugia malayi G-protein coupled receptor 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Schistosoma mansoni nuclear hormone receptor 0.0045 0.0178 0.0204
Loa Loa (eye worm) pyruvate kinase 0.0071 0.0337 0.0502
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0052 0.0093
Onchocerca volvulus 0.0257 0.1468 0.2195
Mycobacterium ulcerans Type I modular polyketide synthase 0.0028 0.0079 0.0149
Onchocerca volvulus 0.0021 0.0035 0.0051
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0053 0.0227 0.0328
Mycobacterium ulcerans thioesterase 0.0024 0.005 0.0089
Brugia malayi Pyruvate kinase, muscle isozyme 0.0071 0.0337 0.0502
Onchocerca volvulus Pyruvate kinase homolog 0.0071 0.0337 0.0502
Leishmania major mitochondrial DNA polymerase beta 0.0304 0.1751 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0114 0.06 0.0896
Schistosoma mansoni nuclear receptor nhr-48 0.0045 0.0178 0.0204
Brugia malayi Calcitonin receptor-like protein seb-1 0.0106 0.0552 0.0824
Brugia malayi RE15519p 0.006 0.0272 0.0405
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0094 0.048 0.0717
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0085 0.0425 0.0424
Trichomonas vaginalis esterase, putative 0.007 0.0331 0.0484
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0034 0.0111 0.0593
Schistosoma mansoni retinoid-x-receptor (RXR) 0.005 0.021 0.0242
Mycobacterium tuberculosis Probable polyketide synthase Pks8 0.0023 0.0048 0.009
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0121 0.0644 0.0743
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.013 0.0698 0.1043
Echinococcus granulosus cation transporting ATPase 13A1 0.0017 0.0008 0.0011
Schistosoma mansoni ets-related 0.0235 0.1333 0.154
Loa Loa (eye worm) hypothetical protein 0.0017 0.0008 0.0011
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Mycobacterium ulcerans hypothetical protein 0.0024 0.0052 0.0093
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.004 0.0148 0.212
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0017 0.0008 0.0009
Brugia malayi bZIP transcription factor family protein 0.0082 0.0407 0.0608
Brugia malayi PAS domain containing protein 0.01 0.0513 0.0765
Mycobacterium ulcerans hypothetical protein 0.016 0.0879 0.1842
Loa Loa (eye worm) MH2 domain-containing protein 0.0378 0.2199 0.3288
Echinococcus multilocularis cation transporting ATPase 13A1 0.0017 0.0008 0.0008
Brugia malayi hypothetical protein 0.0045 0.0178 0.0265
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.007 0.0334 0.0385
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0042 0.0165 0.0246
Loa Loa (eye worm) hypothetical protein 0.0087 0.0437 0.0653
Mycobacterium ulcerans proteasome PrcA 0.0796 0.4734 1
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0117 0.0627
Echinococcus multilocularis allatostatin A receptor 0.006 0.0272 0.0271
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.001 0.001
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0016 0.0011
Schistosoma mansoni smad1 5 8 and 0.0026 0.0064 0.0073
Mycobacterium ulcerans phenolpthiocerol synthesis type-I polyketide synthase PpsA 0.0023 0.0045 0.0079
Loa Loa (eye worm) TK/ROR protein kinase 0.0101 0.0517 0.0772
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Loa Loa (eye worm) hypoxia-induced factor 1 0.0309 0.178 0.2661
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.005 0.021 0.0209
Schistosoma mansoni glutaminase 0.0584 0.3448 0.3984
Schistosoma mansoni RAR-like nuclear receptor 0.0094 0.048 0.0554
Brugia malayi nuclear receptor RXR 0.005 0.021 0.0313
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Schistosoma mansoni hypothetical protein 0.0034 0.0111 0.0128
Echinococcus granulosus copper transporting ATPase 1 0.0017 0.0008 0.0011
Brugia malayi Uncoordinated protein 44 0.0015 0.0001 0.000000057292
Loa Loa (eye worm) hypothetical protein 0.0025 0.0061 0.009
Brugia malayi hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus pyruvate kinase 0.0071 0.0337 0.0502
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0033 0.011 0.0163
Brugia malayi nuclear receptor NHR-88 0.0045 0.0178 0.0265
Schistosoma mansoni lipoxygenase 0.0021 0.0036 0.0041
Schistosoma mansoni neuropeptide F-like receptor 0.006 0.0272 0.0313
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0052 0.0077
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0272 0.0313
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0106 0.0552 0.0824
Echinococcus multilocularis pyruvate kinase 0.0036 0.0128 0.0127
Giardia lamblia Histone acetyltransferase GCN5 0.0033 0.0106 0.0146
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0279 0.0321
Echinococcus granulosus G protein coupled receptor 139 0.006 0.0272 0.0405
Onchocerca volvulus 0.006 0.0272 0.0405
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0091 0.0458 0.0528
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0053 0.0227 0.0338
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0053 0.0227 0.0328
Schistosoma mansoni copper ABC transporter ATPase 0.0017 0.0008 0.0009
Echinococcus granulosus Nuclear hormone receptor HR96 0.0045 0.0178 0.0265
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus 7TM GPCR rhodopsin 0.006 0.0272 0.0405
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0053 0.0227 0.1255
Onchocerca volvulus 0.0045 0.0178 0.0265
Mycobacterium leprae Probable lipase LipE 0.007 0.0331 0.0684
Echinococcus granulosus tumor protein p63 0.0361 0.2099 0.3138
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0053 0.0227 0.0328
Mycobacterium tuberculosis Polyketide synthase Pks12 0.003 0.0089 0.0179
Giardia lamblia Pyruvate kinase 0.0071 0.0337 0.0492
Echinococcus granulosus smad 0.0026 0.0064 0.0094
Brugia malayi Pre-SET motif family protein 0.0091 0.0458 0.0683
Echinococcus granulosus thyroid hormone receptor alpha 0.0045 0.0178 0.0265
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0178 0.0265
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0069
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Onchocerca volvulus 0.0045 0.0178 0.0265
Brugia malayi Augmenter of liver regeneration 0.0035 0.0117 0.0175
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsC 0.0028 0.0079 0.0156
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.035 0.2032 0.2348
Schistosoma mansoni amine GPCR 0.006 0.0272 0.0313
Brugia malayi isocitrate dehydrogenase 0.0034 0.0111 0.0166
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0117 0.0627
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0091 0.0458 0.0528
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0094 0.048 0.0717
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0331 0.0484
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.006 0.0272 0.0271
Brugia malayi hypothetical protein 0.0045 0.0178 0.0265
Echinococcus multilocularis serotonin receptor 0.018 0.0997 0.0996
Mycobacterium leprae probable proteasome (alpha subunit) PrcA 0.0796 0.4734 1
Echinococcus multilocularis aryl hydrocarbon receptor 0.0026 0.0065 0.0064
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0042 0.0165 0.0902
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Schistosoma mansoni aryl hydrocarbon receptor 0.01 0.0513 0.0591
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0042 0.0165 0.0235
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0114 0.06 0.0886
Echinococcus multilocularis enteropeptidase 0.0021 0.0035 0.0034
Schistosoma mansoni smad1 5 8 and 0.0026 0.0064 0.0073
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0045 0.0178 0.0177
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0053
Loa Loa (eye worm) glycogen phosphorylase 0.1118 0.6687 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0698 0.1461
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.006 0.0272 0.0405
Echinococcus multilocularis g protein coupled receptor 0.006 0.0272 0.0271
Echinococcus multilocularis isocitrate dehydrogenase 0.0034 0.0111 0.0111
Echinococcus multilocularis growth factor receptor bound protein 2 0.0152 0.083 0.0829
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.006 0.0272 0.0405
Mycobacterium tuberculosis Conserved hypothetical protein 0.016 0.0879 0.1848
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0085 0.0425 0.0424
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0053 0.0227 0.0328
Onchocerca volvulus 0.007 0.0331 0.0494
Onchocerca volvulus 0.0021 0.0036 0.0053
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0165 0.0235
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD 0.0028 0.0079 0.0149
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.007 0.0334 0.1871
Schistosoma mansoni histamine h1 receptor 0.006 0.0272 0.0313
Schistosoma mansoni zinc finger protein 0.0045 0.0178 0.0204
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus glycogen phosphorylase 0.1118 0.6687 1
Schistosoma mansoni hypothetical protein 0.0067 0.0314 0.0362
Loa Loa (eye worm) hypothetical protein 0.007 0.0331 0.0494
Schistosoma mansoni biogenic amine (5HT) receptor 0.018 0.0997 0.1151
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0514 0.3027 0.4525
Onchocerca volvulus Neuropeptide F receptor homolog 0.006 0.0272 0.0405
Brugia malayi hypothetical protein 0.006 0.0272 0.0405
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0094 0.048 0.0717
Brugia malayi Melatonin receptor type 1A 0.006 0.0272 0.0405
Echinococcus granulosus nervana 2 0.0327 0.1894 0.2831
Loa Loa (eye worm) hypothetical protein 0.0087 0.0437 0.0653
Echinococcus multilocularis neuropeptide FF receptor 2 0.006 0.0272 0.0271
Toxoplasma gondii LsmAD domain-containing protein 0.0027 0.0071 0.1017
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0017 0.0008 0.0007
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.006 0.0272 0.0405
Entamoeba histolytica glycogenphosphorylase, putative 0.0483 0.2839 0.4238
Mycobacterium leprae PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC 0.003 0.0089 0.0172
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0034 0.0111 0.0166
Brugia malayi beta-lactamase family protein 0.007 0.0331 0.0494
Giardia lamblia Flap structure-specific endonuclease 0.0028 0.0076 0.0102
Schistosoma mansoni hypothetical protein 0.0034 0.0111 0.0128
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0046 0.0057
Loa Loa (eye worm) melatonin receptor type 1A 0.006 0.0272 0.0405
Echinococcus granulosus neuropeptide receptor A26 0.006 0.0272 0.0405
Echinococcus multilocularis lysosomal alpha glucosidase 0.0514 0.3027 0.3026
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0148 0.0803
Echinococcus granulosus g-protein coupled receptor 0.006 0.0272 0.0405
Echinococcus multilocularis g protein coupled receptor 0.006 0.0272 0.0271
Onchocerca volvulus 0.006 0.0272 0.0405
Mycobacterium tuberculosis Polyketide synthase Pks2 0.0027 0.0073 0.0145
Toxoplasma gondii prolyl endopeptidase 0.0017 0.0008 0.0117
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.004 0.0148 0.0803
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0028 0.0076 0.0392
Echinococcus granulosus neuropeptide Y receptor 0.006 0.0272 0.0405
Echinococcus granulosus voltage dependent calcium channel 0.0085 0.0425 0.0634
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0034 0.0111 0.0128
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0079 0.0385 0.0384
Onchocerca volvulus Fatty acid synthase homolog 0.0051 0.0216 0.0322
Brugia malayi oxidoreductase, zinc-binding dehydrogenase family protein 0.0053 0.0232 0.0346
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0042 0.0163 0.0889
Echinococcus granulosus glycoprotein Antigen 5 0.0021 0.0035 0.0051
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0016 0.0282
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0052 0.0066
Toxoplasma gondii kringle domain-containing protein 0.0101 0.0517 0.7406
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0272 0.0313
Brugia malayi ecdysteroid receptor 0.0094 0.048 0.0717
Loa Loa (eye worm) intermediate filament protein 0.0055 0.0243 0.0362
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0052 0.0093
Trichomonas vaginalis penicillin-binding protein, putative 0.007 0.0331 0.0484
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0035 0.0117 0.0627
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0042 0.0163 0.0188
Entamoeba histolytica glycogen phosphorylase, putative 0.1118 0.6687 1
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0017 0.0008 0.0008
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.007 0.0331 0.0382
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0052 0.0066
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0026 0.0065 0.0325
Onchocerca volvulus 0.0094 0.048 0.0717
Loa Loa (eye worm) hypothetical protein 0.035 0.2032 0.3038
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.0123 0.025
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0001 0.000000057292
Loa Loa (eye worm) hypothetical protein 0.0021 0.0036 0.0053
Toxoplasma gondii hypothetical protein 0.0017 0.0008 0.0117
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0094 0.048 0.0717
Echinococcus multilocularis conserved hypothetical protein 0.0677 0.4015 0.4015
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0053 0.0227 0.1255
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0533 0.3139 0.4693
Brugia malayi MH2 domain containing protein 0.0378 0.2199 0.3288
Brugia malayi cytoplasmic intermediate filament protein 0.003 0.0087 0.0129
Loa Loa (eye worm) hypothetical protein 0.007 0.0331 0.0494
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0036 0.0053
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.007 0.0092
Schistosoma mansoni hypothetical protein 0.0147 0.0799 0.0923
Brugia malayi nuclear hormone receptor 0.0094 0.048 0.0717
Brugia malayi hypothetical protein 0.0721 0.4279 0.6398
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0272 0.0271
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0055 0.0243 0.0362
Schistosoma mansoni neuropeptide receptor 0.006 0.0272 0.0313
Chlamydia trachomatis pyruvate kinase 0.0071 0.0337 0.0492
Schistosoma mansoni retinoic acid receptor RXR 0.0094 0.048 0.0554
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus multilocularis alpha 1A adrenergic receptor 0.006 0.0272 0.0271
Brugia malayi prolyl oligopeptidase family protein 0.0017 0.0008 0.0011
Brugia malayi Trypsin family protein 0.0021 0.0035 0.0051
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0094 0.048 0.0717
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Echinococcus granulosus cation transporting atpase worm 0.0017 0.0008 0.0011
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0042 0.0163 0.0188
Brugia malayi Isocitrate dehydrogenase 0.0034 0.0111 0.0166
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0094 0.048 0.0717
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0052 0.0093
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0222 0.0256
Echinococcus multilocularis survival motor neuron protein 1 0.0721 0.4279 0.4278
Mycobacterium ulcerans glycogen branching protein 0.0017 0.0013 0.001
Mycobacterium ulcerans Type I modular polyketide synthase 0.0028 0.0079 0.0149
Loa Loa (eye worm) hypothetical protein 0.0085 0.0425 0.0634
Treponema pallidum fructose-bisphosphate aldolase 0.0318 0.1838 1
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0045 0.0178 0.0177
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.0227 0.0328
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0042 0.0165 0.0902
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.006 0.0272 0.0271
Echinococcus multilocularis transmembrane protease serine 3 0.0021 0.0035 0.0034
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0008 0.00000021976
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0036 0.0675
Trypanosoma cruzi P-type H+-ATPase, putative 0.0033 0.0111 0.0589
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0052 0.0222 0.0331
Onchocerca volvulus 0.006 0.0272 0.0405
Trichomonas vaginalis amylase, putative 0.0017 0.0013 0.0007
Echinococcus multilocularis protein dispatched 1 0.0052 0.022 0.022
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Schistosoma mansoni hypothetical protein 0.0854 0.509 0.5881
Mycobacterium ulcerans thioesterase TesA 0.0024 0.005 0.0089
Schistosoma mansoni hypothetical protein 0.0073 0.0348 0.0401
Echinococcus multilocularis tar DNA binding protein 0.0061 0.0279 0.0278
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0111 0.0584 0.0872
Loa Loa (eye worm) nuclear hormone receptor 0.0045 0.0178 0.0265
Schistosoma mansoni inositol monophosphatase 0.004 0.0148 0.017
Echinococcus granulosus peptide allatostatin:somatostatin 0.006 0.0272 0.0405
Schistosoma mansoni hypothetical protein 0.0854 0.509 0.5881
Brugia malayi Trypsin family protein 0.0021 0.0035 0.0051
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Leishmania major P-type H -ATPase, putative 0.0033 0.0111 0.0589
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0085 0.0425 0.0634
Loa Loa (eye worm) hypothetical protein 0.0027 0.0069 0.0103
Brugia malayi Nuclear hormone receptor E75 0.0045 0.0178 0.0265
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.013 0.0698 0.3959
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0034 0.0111 0.0593
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0071 0.0361
Echinococcus granulosus lysosomal alpha glucosidase 0.0514 0.3027 0.4525
Loa Loa (eye worm) hypothetical protein 0.0021 0.0035 0.0051
Brugia malayi Ets-domain containing protein 0.0077 0.0377 0.0563
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0018 0.0016 0.0022
Echinococcus granulosus tissue type plasminogen activator 0.0101 0.0517 0.0772
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0017 0.0008 0.0001
Echinococcus multilocularis Niemann Pick C1 protein 0.0105 0.0546 0.0545
Brugia malayi hypoxia-induced factor 1 0.0309 0.178 0.2661
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0064 0.0073
Loa Loa (eye worm) hypothetical protein 0.0252 0.1435 0.2144
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.003 0.0087 0.0119
Trichomonas vaginalis D-aminoacylase, putative 0.007 0.0331 0.0484
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0121 0.0643 0.0642
Toxoplasma gondii Erv1 / Alr family protein 0.0035 0.0117 0.1682
Loa Loa (eye worm) fatty acid synthase 0.0028 0.0076 0.0113
Echinococcus multilocularis thyroid hormone receptor alpha 0.0094 0.048 0.0479
Schistosoma mansoni rhodopsin-like orphan GPCR 0.006 0.0272 0.0313
Echinococcus granulosus pyruvate kinase 0.0036 0.0128 0.019
Schistosoma mansoni neuropeptide receptor 0.006 0.0272 0.0313
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0022 0.0082
Loa Loa (eye worm) pax transcription factor protein 2 0.0257 0.1468 0.2195
Loa Loa (eye worm) hypothetical protein 0.007 0.0331 0.0494
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0094 0.048 0.0479
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0327 0.1894 0.1893
Echinococcus granulosus neuropeptides capa receptor 0.006 0.0272 0.0405
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.006 0.0272 0.0271
Echinococcus multilocularis protein patched 0.0045 0.0182 0.0181
Brugia malayi Dopamine receptor 0.006 0.0272 0.0405
Mycobacterium tuberculosis Conserved protein 0.007 0.0331 0.0691
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0053 0.0227 0.0226
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0023 0.0047 0.0069
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0094 0.048 0.0717
Brugia malayi Pax transcription factor protein 2 0.0257 0.1468 0.2195
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0028 0.0076 0.0392
Echinococcus multilocularis prolyl endopeptidase 0.0017 0.0008 0.0007
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0064 0.0296 0.061
Plasmodium vivax calcium-transporting ATPase, putative 0.0053 0.0227 0.4375
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0027 0.0069 0.0103
Onchocerca volvulus 0.0017 0.0008 0.001
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0022 0.0032
Schistosoma mansoni glycogen phosphorylase 0.1118 0.6687 0.7727
Brugia malayi Protein kinase domain containing protein 0.0015 0.0001 0.000000057292
Loa Loa (eye worm) hypothetical protein 0.005 0.021 0.0313
Schistosoma mansoni hypothetical protein 0.006 0.0272 0.0313
Echinococcus granulosus inositol monophosphatase 1 0.004 0.0148 0.022
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0021 0.0035 0.004
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0114 0.06 0.0886
Mycobacterium leprae Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas 0.003 0.0089 0.0172
Brugia malayi prolyl oligopeptidase family protein 0.0017 0.0008 0.0011
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0064 0.0063
Brugia malayi Pre-SET motif family protein 0.0632 0.3743 0.5597
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Echinococcus multilocularis lamin 0.0055 0.0243 0.0242
Echinococcus multilocularis copper transporting ATPase 1 0.0017 0.0008 0.0008
Schistosoma mansoni alpha glucosidase 0.0114 0.06 0.0692
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Schistosoma mansoni amine GPCR 0.006 0.0272 0.0313
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0042 0.0163 0.0232
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0052 0.0253
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.007 0.0331 0.0691
Onchocerca volvulus 0.006 0.0272 0.0405
Echinococcus granulosus Niemann Pick C1 protein 0.0105 0.0546 0.0815
Mycobacterium ulcerans esterase/lipase LipP 0.007 0.0331 0.0684
Mycobacterium tuberculosis Phenolpthiocerol synthesis type-I polyketide synthase PpsD 0.0028 0.0079 0.0156
Brugia malayi Dopamine receptor protein 2 0.006 0.0272 0.0405
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0021 0.0035 0.0051
Brugia malayi Sex muscle abnormal protein 5 0.0152 0.083 0.124
Leishmania major proton motive ATPase, putative 0.0017 0.0008 0.0001
Echinococcus multilocularis neuropeptides capa receptor 0.006 0.0272 0.0271
Loa Loa (eye worm) hypothetical protein 0.0053 0.0228 0.034
Plasmodium vivax flap endonuclease 1, putative 0.0028 0.0076 0.1459
Brugia malayi hypothetical protein 0.0017 0.0013 0.0018
Mycobacterium ulcerans polyketide synthase Pks9 0.0019 0.0021 0.0027
Loa Loa (eye worm) steroid hormone receptor 0.0094 0.048 0.0717
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0001 0.000000038312
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0022 0.0037
Loa Loa (eye worm) hypothetical protein 0.0094 0.048 0.0717
Giardia lamblia Glycogen phosphorylase 0.1118 0.6687 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.006 0.0272 0.0271
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0087 0.0437 0.0653
Loa Loa (eye worm) glutaminase 2 0.0584 0.3448 0.5156
Loa Loa (eye worm) hypothetical protein 0.0071 0.0337 0.0502
Onchocerca volvulus 0.0297 0.1712 0.2558
Loa Loa (eye worm) hypothetical protein 0.0045 0.0178 0.0265
Echinococcus multilocularis rhodopsin orphan GPCR 0.006 0.0272 0.0271
Echinococcus multilocularis glycogen phosphorylase 0.1118 0.6687 0.6687
Schistosoma mansoni alpha-1 adrenergic receptor 0.006 0.0272 0.0313
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0085 0.0425 0.049
Plasmodium vivax SET domain protein, putative 0.0091 0.0458 0.8847
Loa Loa (eye worm) pyruvate kinase 0.0071 0.0337 0.0502
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0075 0.0361 0.036
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0035 0.0117 0.0627
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0052 0.0093
Loa Loa (eye worm) G-protein coupled receptor 0.006 0.0272 0.0405
Brugia malayi gonadotropin-releasing hormone receptor 2 0.006 0.0272 0.0405
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0052 0.0093
Brugia malayi hypothetical protein 0.005 0.021 0.0313
Brugia malayi Serotonin receptor 0.006 0.0272 0.0405
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0094 0.048 0.0554
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0144 0.078 0.4429
Echinococcus granulosus neuropeptide receptor 0.006 0.0272 0.0405
Echinococcus granulosus tm gpcr rhodopsin 0.006 0.0272 0.0405
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0053 0.0227 0.1255
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0118 0.0623 0.0622
Echinococcus multilocularis neuropeptide receptor A26 0.006 0.0272 0.0271
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0053 0.0227 0.3249
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0128 0.0686 0.1025
Onchocerca volvulus 0.01 0.0517 0.0771
Trichomonas vaginalis alpha-glucosidase, putative 0.0042 0.0165 0.0235
Echinococcus granulosus acylamino acid releasing enzyme 0.0017 0.0008 0.0011
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0008 0.0001
Loa Loa (eye worm) hypothetical protein 0.0101 0.0517 0.0772
Brugia malayi hypothetical protein 0.0021 0.0035 0.0051
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0209 0.1177 0.1759
Echinococcus granulosus nervana 2 0.0327 0.1894 0.2831
Trypanosoma brucei pyruvate kinase 1 0.0071 0.0337 0.1885
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0022 0.0032
Schistosoma mansoni myosin xvIII 0.006 0.0272 0.0313
Schistosoma mansoni thyroid hormone receptor 0.0094 0.048 0.0554
Brugia malayi RNA binding protein 0.0061 0.0279 0.0416
Entamoeba histolytica 1,4-alpha-glucan branching enzyme, putative 0.0017 0.0013 0.0007
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0026 0.0065 0.0064
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.007 0.0331 0.0684
Echinococcus multilocularis Glycosyl transferase, family 35 0.1118 0.6687 0.6687
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0222 0.0221
Onchocerca volvulus 0.006 0.0272 0.0405
Brugia malayi hypothetical protein 0.0252 0.1435 0.2144
Echinococcus granulosus expressed conserved protein 0.0099 0.0507 0.0758
Loa Loa (eye worm) hypothetical protein 0.0066 0.0309 0.0461
Schistosoma mansoni nuclear receptor 0.0045 0.0178 0.0204
Schistosoma mansoni growth factor receptor-bound protein 0.0152 0.083 0.0958
Onchocerca volvulus 0.006 0.0272 0.0405
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0052 0.0077
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0091 0.0458 0.0457
Onchocerca volvulus Prolyl endopeptidase homolog 0.0017 0.0008 0.0011
Brugia malayi Dopamine receptor protein 1 0.006 0.0272 0.0405
Echinococcus granulosus sex peptide receptor 0.006 0.0272 0.0405
Echinococcus multilocularis Protein lozenge 0.0055 0.0244 0.0243
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0094 0.048 0.0717
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0318 0.1838 0.274
Echinococcus granulosus nuclear receptor nhr 48 0.0045 0.0178 0.0265
Schistosoma mansoni biogenic amine (dopamine) receptor 0.006 0.0272 0.0313
Entamoeba histolytica alpha-amylase family protein 0.0039 0.0145 0.0205
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0064 0.0063
Echinococcus multilocularis RUN 0.0021 0.0036 0.0035
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0045 0.0178 0.0177
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0155 0.0851 0.1789
Echinococcus multilocularis fmrfamide receptor 0.006 0.0272 0.0271
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0065 0.0325
Brugia malayi larval opioid receptor 0.006 0.0272 0.0405
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0042 0.0165 0.0235
Echinococcus multilocularis nervana 2 0.0533 0.3139 0.3139
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.013 0.0698 0.1467
Brugia malayi Beta-ketoacyl synthase, N-terminal domain containing protein 0.0028 0.0079 0.0117
Brugia malayi tailless protein 0.0045 0.0178 0.0265
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0017 0.0008 0.0009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0052 0.01
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0094 0.048 0.0717
Schistosoma mansoni intracisternal A-particle retropepsin (A02 family) 0.1442 0.8654 1
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0094 0.048 0.0554
Loa Loa (eye worm) hypothetical protein 0.0049 0.0207 0.0308
Loa Loa (eye worm) hypothetical protein 0.016 0.0878 0.1312
Brugia malayi Smad1 0.0026 0.0064 0.0094
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0533 0.3139 0.3139
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0017 0.0008 0.0011
Brugia malayi orphan nuclear receptor NR2E1 0.0045 0.0178 0.0265
Onchocerca volvulus 0.0033 0.011 0.0163
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0042 0.0163 0.0889
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0036 0.0124 0.0246
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0026 0.0065 0.0325
Mycobacterium ulcerans putative regulatory protein 0.0074 0.0355 0.0735
Plasmodium vivax ataxin-2 like protein, putative 0.0027 0.0071 0.1354
Leishmania major hypothetical protein, conserved 0.0035 0.0117 0.0627
Schistosoma mansoni glycogen phosphorylase 0.0483 0.2839 0.328
Onchocerca volvulus 0.006 0.0272 0.0405
Schistosoma mansoni single-minded 0.01 0.0513 0.0591
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1838 0.274
Trichomonas vaginalis alpha-glucosidase, putative 0.0114 0.06 0.0886
Schistosoma mansoni tar DNA-binding protein 0.0061 0.0279 0.0321
Echinococcus granulosus pyruvate kinase 0.0071 0.0337 0.0502
Schistosoma mansoni alpha-glucosidase 0.0443 0.2592 0.2995
Loa Loa (eye worm) hypothetical protein 0.006 0.0272 0.0405
Schistosoma mansoni opsin-like receptor 0.006 0.0272 0.0313
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.006 0.0272 0.0313
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0304 0.1751 1
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0045 0.0178 0.0204
Echinococcus multilocularis pyruvate kinase 0.0071 0.0337 0.0336
Entamoeba histolytica glycogen phosphorylase, putative 0.0483 0.2839 0.4238
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0036 0.0035
Onchocerca volvulus Huntingtin homolog 0.0252 0.1435 0.2144
Trypanosoma brucei pyruvate kinase 1, putative 0.0071 0.0337 0.1885
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0182 0.027
Echinococcus multilocularis expressed conserved protein 0.0099 0.0507 0.0507
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0064 0.0094
Brugia malayi Glycosyl hydrolases family 31 protein 0.0514 0.3027 0.4525
Onchocerca volvulus 0.0441 0.2586 0.3866
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0023 0.0047 0.0223
Echinococcus multilocularis glucan (1,4 alpha), branching enzyme 1 0.0017 0.0013 0.0012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0318 0.1838 0.274
Brugia malayi hypothetical protein 0.0054 0.0234 0.0348
Brugia malayi prolyl oligopeptidase family protein 0.007 0.0334 0.0499
Schistosoma mansoni inositol monophosphatase 0.004 0.0148 0.017
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0272 0.0405
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0272 0.0405
Echinococcus multilocularis Smad4 0.0026 0.0064 0.0063
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0053 0.0227 0.1255
Mycobacterium ulcerans multifunctional mycocerosic acid synthase membrane-associated Mas 0.003 0.0089 0.0172
Mycobacterium tuberculosis Probable esterase LipL 0.007 0.0331 0.0691
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0064 0.0296 0.0616
Echinococcus granulosus single minded 2 0.0074 0.0355 0.053
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0016 0.0016
Mycobacterium ulcerans Type I modular polyketide synthase 0.0028 0.0079 0.0149
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0078 0.0381 0.0569
Brugia malayi hypothetical protein 0.0441 0.2586 0.3866
Loa Loa (eye worm) hypothetical protein 0.0092 0.0468 0.0698
Echinococcus granulosus thyrotropin releasing hormone receptor 0.006 0.0272 0.0405
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0019 0.0024 0.0089
Echinococcus multilocularis microtubule associated protein 2 0.0688 0.4081 0.408
Trypanosoma cruzi pyruvate kinase 2, putative 0.0071 0.0337 0.1885
Schistosoma mansoni steroid hormone receptor ad4bp 0.0094 0.048 0.0554
Echinococcus granulosus flap endonuclease 1 0.0028 0.0076 0.0113
Mycobacterium ulcerans aldehyde dehydrogenase 0.013 0.0698 0.1461
Echinococcus granulosus tm gpcr rhodopsin 0.0873 0.5201 0.7777
Loa Loa (eye worm) hypothetical protein 0.0121 0.0644 0.0962
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0091 0.0458 0.6554
Loa Loa (eye worm) RNA binding protein 0.0061 0.0279 0.0416
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.006 0.0272 0.0405
Echinococcus granulosus rhodopsin orphan GPCR 0.006 0.0272 0.0405
Leishmania major pteridine reductase 1 0.0196 0.1096 0.6241
Echinococcus multilocularis neuropeptide Y receptor 0.006 0.0272 0.0271
Onchocerca volvulus 0.0101 0.0517 0.0772
Mycobacterium ulcerans pyruvate kinase 0.0071 0.0337 0.0695
Brugia malayi Na,K-ATPase alpha subunit 0.0128 0.0686 0.1025
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0094 0.048 0.0717
Trichomonas vaginalis alpha-amylase, putative 0.0039 0.0145 0.0205
Loa Loa (eye worm) hypothetical protein 0.0091 0.0458 0.0683
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0053 0.0227 0.0328
Plasmodium vivax cation transporting ATPase, putative 0.0017 0.0008 0.014
Brugia malayi G-protein coupled receptor 0.006 0.0272 0.0405
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0008 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0094 0.048 0.0717
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0222 0.0331
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0016 0.0023
Brugia malayi hypothetical protein 0.0065 0.03 0.0448
Loa Loa (eye worm) hypothetical protein 0.0024 0.0052 0.0077
Onchocerca volvulus 0.0074 0.0355 0.053
Trichomonas vaginalis cation-transporting ATPase, putative 0.0033 0.0111 0.0154
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0873 0.5201 0.5201
Schistosoma mansoni growth factor receptor-bound protein 0.0152 0.083 0.0958
Loa Loa (eye worm) TAR-binding protein 0.0061 0.0279 0.0416
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.007 0.0331 0.0494
Loa Loa (eye worm) hypothetical protein 0.0094 0.048 0.0717
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.006 0.0272 0.0405
Loa Loa (eye worm) hypothetical protein 0.0042 0.0165 0.0246
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0036 0.0035
Echinococcus multilocularis nervana 2 0.0533 0.3139 0.3139
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.006 0.0272 0.0313
Loa Loa (eye worm) hypothetical protein 0.0252 0.1435 0.2144
Onchocerca volvulus 0.0065 0.03 0.0448
Loa Loa (eye worm) hypothetical protein 0.0054 0.0234 0.0348
Trichomonas vaginalis starch branching enzyme II, putative 0.0017 0.0013 0.0007
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.006 0.0272 0.0271
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0033 0.011 0.0222
Schistosoma mansoni cercarial elastase (S01 family) 0.0021 0.0035 0.004
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0017 0.0008 0.0011
Echinococcus multilocularis GPCR, family 2 0.0034 0.0111 0.0111
Echinococcus multilocularis pyruvate kinase 0.0036 0.0128 0.0127
Loa Loa (eye worm) hypothetical protein 0.018 0.0997 0.149
Schistosoma mansoni rab6-interacting 0.0021 0.0036 0.0041

Activities

Activity type Activity value Assay description Source Reference
EC50 (functional) = 637 nM Agonist activity at APJ receptor (unknown origin) expressed in CHO cells co-expressing with Calphaq16 assessed as calcium mobilization ChEMBL. 24755525
Emax (functional) = 67 % Agonist activity at APJ receptor (unknown origin) expressed in CHO cells co-expressing with Calphaq16 assessed as calcium mobilization relative to pyr-apelin-13 ChEMBL. 24755525

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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