Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | expressed conserved protein | 0.0097 | 0.1229 | 0.1622 |
Brugia malayi | Ceramide glucosyltransferase | 0.0421 | 0.758 | 0.758 |
Brugia malayi | Endonuclease/Exonuclease/phosphatase family protein | 0.01 | 0.1292 | 0.1292 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0034 | 0 | 0.5 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0034 | 0 | 0.5 |
Echinococcus multilocularis | neutral sphingomyelinase | 0.01 | 0.1292 | 0.1704 |
Mycobacterium ulcerans | hydrolase/amidase | 0.0285 | 0.4921 | 1 |
Echinococcus granulosus | hypothetical protein | 0.0097 | 0.1229 | 0.1622 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0421 | 0.758 | 1 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0 | 0.5 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0191 | 0.3072 | 0.5 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0421 | 0.758 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0034 | 0 | 0.5 |
Echinococcus granulosus | neutral sphingomyelinase | 0.01 | 0.1292 | 0.1704 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0 | 0.5 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0034 | 0 | 0.5 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0421 | 0.758 | 1 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0421 | 0.758 | 0.758 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0034 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1292 | 0.1292 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0421 | 0.758 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0034 | 0 | 0.5 |
Echinococcus granulosus | expressed conserved protein | 0.0097 | 0.1229 | 0.1622 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0545 | 1 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0034 | 0 | 0.5 |
Echinococcus multilocularis | conserved hypothetical protein | 0.0097 | 0.1229 | 0.1622 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0421 | 0.758 | 1 |
Schistosoma mansoni | neutral sphingomyelinase | 0.01 | 0.1292 | 0.1704 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.