Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0238 | 0.6887 | 0.6799 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0085 | 0.1643 | 0.6123 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0871 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0871 | 0.0871 |
Echinococcus granulosus | zinc finger protein Ran binding | 0.0085 | 0.1643 | 0.1643 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Echinococcus granulosus | cathepsin l1 | 0.0045 | 0.0277 | 0.0277 |
Onchocerca volvulus | 0.0085 | 0.1643 | 0.2065 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0115 | 0.2682 | 0.2682 |
Loa Loa (eye worm) | ctsf protein | 0.0062 | 0.0871 | 0.0611 |
Echinococcus granulosus | cathepsin b | 0.0329 | 1 | 1 |
Onchocerca volvulus | 0.0085 | 0.1643 | 0.2065 | |
Loa Loa (eye worm) | fibroinase | 0.0062 | 0.0871 | 0.0611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Echinococcus granulosus | cathepsin l1 | 0.0062 | 0.0871 | 0.0871 |
Brugia malayi | YY1-associated factor 2 | 0.0085 | 0.1643 | 0.1643 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0329 | 1 | 1 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0238 | 0.6887 | 0.6887 |
Leishmania major | hypothetical protein, conserved | 0.0085 | 0.1643 | 0.4258 |
Echinococcus multilocularis | ring and YY1 binding protein | 0.0085 | 0.1643 | 0.1643 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0085 | 0.1643 | 0.6123 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1643 | 0.1404 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0045 | 0.0277 | 0.0277 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0238 | 0.6887 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0115 | 0.2682 | 0.3895 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0238 | 0.6887 | 0.6887 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0062 | 0.0871 | 0.0611 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Onchocerca volvulus | 0.0062 | 0.0871 | 0.0899 | |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0062 | 0.0871 | 0.0871 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Brugia malayi | brahma associated protein 60 kDa | 0.0238 | 0.6887 | 0.6887 |
Schistosoma mansoni | hypothetical protein | 0.0238 | 0.6887 | 0.6887 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0871 | 0.0871 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0238 | 0.6887 | 1 |
Onchocerca volvulus | Ubiquitin thioesterase ZRANB1 homolog | 0.0085 | 0.1643 | 0.2065 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0062 | 0.0871 | 0.0871 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0085 | 0.1643 | 0.1643 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0871 | 0.0871 |
Schistosoma mansoni | TRABID protein (C64 family) | 0.0085 | 0.1643 | 0.1643 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0045 | 0.0277 | 0.0403 |
Schistosoma mansoni | hypothetical protein | 0.0238 | 0.6887 | 0.6887 |
Plasmodium vivax | hypothetical protein, conserved | 0.0238 | 0.6887 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0238 | 0.6887 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0062 | 0.0871 | 0.0871 |
Schistosoma mansoni | brg-1 associated factor | 0.0238 | 0.6887 | 0.6887 |
Schistosoma mansoni | hypothetical protein | 0.0085 | 0.1643 | 0.1643 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0115 | 0.2682 | 0.2682 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0062 | 0.0871 | 0.0871 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0238 | 0.6887 | 0.6887 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Toxoplasma gondii | cathepsin B | 0.0115 | 0.2682 | 0.3011 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Loa Loa (eye worm) | hypothetical protein | 0.0329 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0115 | 0.2682 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0045 | 0.0277 | 0.0277 |
Giardia lamblia | Cathepsin B precursor | 0.0115 | 0.2682 | 0.5 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0085 | 0.1643 | 0.1643 |
Loa Loa (eye worm) | cysteine protease | 0.0062 | 0.0871 | 0.0611 |
Echinococcus multilocularis | Nuclear pore complex protein Nup153 | 0.0085 | 0.1643 | 0.1643 |
Schistosoma mansoni | hypothetical protein | 0.0238 | 0.6887 | 0.6887 |
Echinococcus granulosus | ring and YY1 binding protein | 0.0085 | 0.1643 | 0.1643 |
Echinococcus multilocularis | zinc finger protein Ran binding | 0.0085 | 0.1643 | 0.1643 |
Giardia lamblia | Cathepsin B precursor | 0.0115 | 0.2682 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1643 | 0.1404 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0045 | 0.0277 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0062 | 0.0871 | 0.1265 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0871 | 0.0871 |
Plasmodium vivax | vivapain-2 | 0.0062 | 0.0871 | 0.1265 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1643 | 0.1404 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0329 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Loa Loa (eye worm) | brahma associated protein | 0.0238 | 0.6887 | 0.6799 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0085 | 0.1643 | 0.6123 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0329 | 1 | 1 |
Schistosoma mansoni | RNA binding protein | 0.0085 | 0.1643 | 0.1643 |
Onchocerca volvulus | 0.0062 | 0.0871 | 0.0899 | |
Plasmodium vivax | vivapain-2 | 0.0062 | 0.0871 | 0.1265 |
Echinococcus multilocularis | cathepsin b | 0.0329 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0871 | 0.0871 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.0871 | 0.0611 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0085 | 0.1643 | 0.1643 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0238 | 0.6887 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0871 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0045 | 0.0277 | 0.0277 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0085 | 0.1643 | 0.1643 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0329 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0085 | 0.1643 | 0.1643 |
Leishmania major | hypothetical protein, conserved | 0.0085 | 0.1643 | 0.4258 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0238 | 0.6887 | 0.6887 |
Onchocerca volvulus | Cathepsin F homolog | 0.0062 | 0.0871 | 0.0899 |
Leishmania major | hypothetical protein, conserved | 0.0085 | 0.1643 | 0.4258 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0238 | 0.6887 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Onchocerca volvulus | 0.0062 | 0.0871 | 0.0899 | |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0085 | 0.1643 | 0.1643 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0062 | 0.0871 | 0.1265 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0085 | 0.1643 | 0.1643 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0085 | 0.1643 | 0.6123 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0238 | 0.6887 | 0.6887 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0045 | 0.0277 | 0.0403 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1643 | 0.1404 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1643 | 0.1404 |
Giardia lamblia | Cathepsin B precursor | 0.0115 | 0.2682 | 0.5 |
Brugia malayi | brahma associated protein 60 kDa | 0.0238 | 0.6887 | 0.6887 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0238 | 0.6887 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0871 | 0.0871 |
Schistosoma mansoni | zinc finger protein | 0.0085 | 0.1643 | 0.1643 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0115 | 0.2682 | 1 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0238 | 0.6887 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0062 | 0.0871 | 0.0611 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0045 | 0.0277 | 0.0277 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0329 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0329 | 1 | 1 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0085 | 0.1643 | 0.1643 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0085 | 0.1643 | 0.1643 |
Onchocerca volvulus | 0.0062 | 0.0871 | 0.0899 | |
Schistosoma mansoni | fusion | 0.0085 | 0.1643 | 0.1643 |
Onchocerca volvulus | 0.0062 | 0.0871 | 0.0899 | |
Echinococcus multilocularis | cysteine protease | 0.0062 | 0.0871 | 0.0871 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0085 | 0.1643 | 0.1643 |
Brugia malayi | Cathepsin L-like precursor | 0.0045 | 0.0277 | 0.0277 |
Toxoplasma gondii | ran binding protein | 0.0085 | 0.1643 | 0.1282 |
Onchocerca volvulus | Cathepsin L homolog | 0.0062 | 0.0871 | 0.0899 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0062 | 0.0871 | 0.0871 |
Entamoeba histolytica | cysteine protease, putative | 0.0062 | 0.0871 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0045 | 0.0277 | 0.0277 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0871 | 0.0871 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0085 | 0.1643 | 0.1643 |
Onchocerca volvulus | 0.0085 | 0.1643 | 0.2065 | |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0062 | 0.0871 | 0.1265 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0238 | 0.6887 | 0.6887 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0062 | 0.0871 | 0.0871 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0062 | 0.0871 | 0.0871 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0871 | 0.0871 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Onchocerca volvulus | 0.0085 | 0.1643 | 0.2065 | |
Onchocerca volvulus | Cathepsin L homolog | 0.0062 | 0.0871 | 0.0899 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Echinococcus multilocularis | Zinc finger, RanBP2 type | 0.0085 | 0.1643 | 0.1643 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0871 | 0.0871 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0062 | 0.0871 | 0.0871 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0062 | 0.0871 | 0.0871 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0062 | 0.0871 | 0.0871 |
Plasmodium falciparum | zinc finger Ran-binding domain-containing protein 2, putative | 0.0085 | 0.1643 | 0.2385 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0085 | 0.1643 | 0.1643 |
Echinococcus multilocularis | cysteine protease | 0.0062 | 0.0871 | 0.0871 |
Leishmania major | hypothetical protein, conserved | 0.0085 | 0.1643 | 0.4258 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0062 | 0.0871 | 0.0871 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Loa Loa (eye worm) | cathepsin B | 0.0115 | 0.2682 | 0.2474 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Chlamydia trachomatis | SWIB complex protein | 0.0238 | 0.6887 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0085 | 0.1643 | 0.4258 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0085 | 0.1643 | 0.1643 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Onchocerca volvulus | 0.0062 | 0.0871 | 0.0899 | |
Echinococcus granulosus | Nuclear pore complex protein Nup153 | 0.0085 | 0.1643 | 0.1643 |
Echinococcus multilocularis | cathepsin b | 0.0329 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0238 | 0.6887 | 0.6887 |
Brugia malayi | Zn-finger in Ran binding protein and others containing protein | 0.0085 | 0.1643 | 0.1643 |
Toxoplasma gondii | Zn-finger in Ran binding protein and others domain-containing protein | 0.0085 | 0.1643 | 0.1282 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0062 | 0.0871 | 0.1265 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0062 | 0.0871 | 0.3248 |
Echinococcus granulosus | Zinc finger RanBP2 type | 0.0085 | 0.1643 | 0.1643 |
Onchocerca volvulus | 0.0062 | 0.0871 | 0.0899 | |
Onchocerca volvulus | 0.0238 | 0.6887 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.