Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0128 | 0.1067 | 0.1067 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0159 | 0.1444 | 0.393 |
Echinococcus multilocularis | tumor protein p63 | 0.0392 | 0.4272 | 0.4272 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.0181 | 0.0223 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0128 | 0.1067 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Echinococcus granulosus | cysteine protease | 0.0128 | 0.1067 | 0.1067 |
Echinococcus multilocularis | cathepsin L | 0.0062 | 0.026 | 0.026 |
Echinococcus granulosus | Mastin | 0.0045 | 0.0053 | 0.0053 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0145 | 0.1277 | 0.1277 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Plasmodium falciparum | dipeptidyl aminopeptidase 3 | 0.0062 | 0.026 | 0.0273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Onchocerca volvulus | 0.0048 | 0.0087 | 0.0153 | |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Plasmodium falciparum | serine repeat antigen 6 | 0.0062 | 0.026 | 0.0273 |
Giardia lamblia | Cathepsin B precursor | 0.031 | 0.3272 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0226 | 0.2251 | 0.2251 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0226 | 0.2251 | 0.2251 |
Onchocerca volvulus | 0.0226 | 0.2251 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0411 | 0.4504 | 0.4504 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0045 | 0.0053 | 0.0053 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0151 | 0.135 | 0.135 |
Onchocerca volvulus | 0.0057 | 0.0205 | 0.0694 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.031 | 0.3272 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0863 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.032 | 0.032 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0062 | 0.0262 | 0.0262 |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0151 | 0.135 | 0.135 |
Trypanosoma cruzi | cysteine protease, putative | 0.0128 | 0.1067 | 0.1067 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0222 | 0.2205 | 0.2205 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0226 | 0.2251 | 0.2251 |
Echinococcus multilocularis | calpain A | 0.0112 | 0.0871 | 0.0871 |
Toxoplasma gondii | preprocathepsin c precursor, putative | 0.0062 | 0.026 | 0.0472 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | trypsin family protein | 0.0045 | 0.0053 | 0.0053 |
Onchocerca volvulus | 0.0226 | 0.2251 | 1 | |
Leishmania major | mitochondrial DNA polymerase beta | 0.0307 | 0.3245 | 0.9915 |
Loa Loa (eye worm) | cysteine protease | 0.0226 | 0.2251 | 0.2251 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0226 | 0.2251 | 0.2251 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0055 | 0.0181 | 0.0181 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0062 | 0.026 | 0.026 |
Plasmodium falciparum | serine repeat antigen 7 | 0.0062 | 0.026 | 0.0273 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Leishmania major | cathepsin L-like protease | 0.0226 | 0.2251 | 0.6879 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0151 | 0.135 | 0.3618 |
Plasmodium vivax | dipeptidyl aminopeptidase 1, putative | 0.0062 | 0.026 | 0.1155 |
Brugia malayi | fibroinase precursor | 0.0062 | 0.026 | 0.026 |
Loa Loa (eye worm) | MBCTL1 | 0.0063 | 0.0274 | 0.0274 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0151 | 0.135 | 0.4125 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0062 | 0.026 | 0.026 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0063 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0062 | 0.026 | 0.026 |
Echinococcus multilocularis | enteropeptidase | 0.0045 | 0.0053 | 0.0053 |
Toxoplasma gondii | cathepsin CPC2 | 0.0062 | 0.026 | 0.0472 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.0292 | 0.0292 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0226 | 0.2251 | 0.2251 |
Brugia malayi | Cathepsin L-like precursor | 0.0226 | 0.2251 | 0.2251 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0062 | 0.026 | 0.026 |
Onchocerca volvulus | Cathepsin L homolog | 0.0062 | 0.026 | 0.0942 |
Plasmodium vivax | vivapain-3 | 0.0128 | 0.1067 | 0.4741 |
Plasmodium vivax | vivapain-2 | 0.0226 | 0.2251 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0226 | 0.2251 | 0.2251 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0226 | 0.2251 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0151 | 0.135 | 0.5 |
Plasmodium vivax | unspecified product | 0.0062 | 0.026 | 0.1155 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0151 | 0.135 | 0.3618 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0128 | 0.1067 | 0.4054 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0045 | 0.0053 | 0.0053 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0159 | 0.1444 | 0.1444 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0222 | 0.2205 | 0.2205 |
Loa Loa (eye worm) | cysteine proteinase cathepsin Z | 0.0062 | 0.026 | 0.026 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Loa Loa (eye worm) | hypothetical protein | 0.0063 | 0.0274 | 0.0274 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0159 | 0.1444 | 0.5946 |
Plasmodium vivax | vivapain-2 | 0.0226 | 0.2251 | 1 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0045 | 0.0053 | 0.0053 |
Leishmania major | mitochondrial DNA polymerase beta-PAK, putative | 0.0145 | 0.1277 | 0.3901 |
Echinococcus multilocularis | cysteine protease | 0.0226 | 0.2251 | 0.2251 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0315 | 0.0315 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.0204 | 0.0204 |
Brugia malayi | cathepsin L-like precursor | 0.0159 | 0.1444 | 0.1444 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Onchocerca volvulus | 0.0159 | 0.1444 | 0.6328 | |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0062 | 0.026 | 0.1155 |
Brugia malayi | hypothetical protein | 0.0125 | 0.1024 | 0.1024 |
Schistosoma mansoni | hypothetical protein | 0.034 | 0.3643 | 0.3643 |
Toxoplasma gondii | cathepsin B | 0.031 | 0.3272 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Echinococcus granulosus | enteropeptidase | 0.0045 | 0.0053 | 0.0053 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0045 | 0.0053 | 0.0053 |
Leishmania major | hypothetical protein, conserved | 0.0057 | 0.0204 | 0.0624 |
Brugia malayi | mbt repeat family protein | 0.0055 | 0.0181 | 0.0181 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0053 | 0.0149 | 0.0149 |
Toxoplasma gondii | cathepsin CPC1 | 0.0062 | 0.026 | 0.0472 |
Plasmodium falciparum | serine repeat antigen 2 | 0.0062 | 0.026 | 0.0273 |
Echinococcus granulosus | cathepsin L | 0.0128 | 0.1067 | 0.1067 |
Loa Loa (eye worm) | ctsf protein | 0.0226 | 0.2251 | 0.2251 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0112 | 0.0871 | 0.0871 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0151 | 0.135 | 0.59 |
Schistosoma mansoni | cathepsin s | 0.0066 | 0.0315 | 0.0315 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.0292 | 0.0292 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0863 | 1 | 1 |
Brugia malayi | Trypsin family protein | 0.0045 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0053 | 0.0053 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0226 | 0.2251 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1024 | 0.1024 |
Echinococcus granulosus | calpain A | 0.0112 | 0.0871 | 0.0871 |
Giardia lamblia | Cathepsin B precursor | 0.031 | 0.3272 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0128 | 0.1067 | 0.4054 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.031 | 0.3272 | 0.3272 |
Brugia malayi | Cathepsin L-like precursor | 0.0226 | 0.2251 | 0.2251 |
Plasmodium falciparum | serine repeat antigen 8 | 0.0062 | 0.026 | 0.0273 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0151 | 0.135 | 0.135 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0057 | 0.0204 | 0.0204 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0062 | 0.026 | 0.026 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Plasmodium vivax | serine-repeat antigen 4 (SERA), putative | 0.0062 | 0.026 | 0.1155 |
Plasmodium vivax | serine-repeat antigen 4 (SERA) | 0.0062 | 0.026 | 0.1155 |
Brugia malayi | calpain family protein 1 | 0.0107 | 0.0812 | 0.0812 |
Onchocerca volvulus | 0.0226 | 0.2251 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.0468 | 0.0468 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Plasmodium vivax | serine-repeat antigen 3 (SERA) | 0.0062 | 0.026 | 0.1155 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0063 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0055 | 0.0181 | 0.0181 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Brugia malayi | Kringle domain containing protein | 0.0057 | 0.0204 | 0.0204 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.1024 | 0.4417 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0062 | 0.026 | 0.026 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0226 | 0.2251 | 0.2251 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0062 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0204 | 0.0204 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0092 | 0.0623 | 0.0623 |
Mycobacterium ulcerans | hypothetical protein | 0.0162 | 0.1476 | 1 |
Plasmodium vivax | dipeptidyl aminopeptidase 2, putative | 0.0062 | 0.026 | 0.1155 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0062 | 0.026 | 0.026 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.0623 | 0.0623 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0623 | 0.0623 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0055 | 0.0181 | 0.0181 |
Trypanosoma brucei | mitochondrial DNA polymerase beta-PAK | 0.0145 | 0.1277 | 0.3901 |
Schistosoma mansoni | survival motor neuron protein | 0.0048 | 0.0087 | 0.0087 |
Echinococcus multilocularis | cathepsin b | 0.0863 | 1 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0092 | 0.0623 | 0.0623 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0151 | 0.135 | 0.3618 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Onchocerca volvulus | 0.0226 | 0.2251 | 1 | |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0307 | 0.3245 | 0.3245 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0062 | 0.026 | 0.1155 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0087 | 0.0087 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0151 | 0.135 | 0.135 |
Toxoplasma gondii | kringle domain-containing protein | 0.0057 | 0.0204 | 0.0295 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0133 | 0.1126 | 0.1126 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Leishmania major | cathepsin L-like protease | 0.0226 | 0.2251 | 0.6879 |
Plasmodium falciparum | serine repeat antigen 1 | 0.0062 | 0.026 | 0.0273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0226 | 0.2251 | 0.2251 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0079 | 0.0468 | 0.0468 |
Brugia malayi | Cathepsin L-like precursor | 0.0159 | 0.1444 | 0.1444 |
Leishmania major | cysteine peptidase A (CPA) | 0.0226 | 0.2251 | 0.6879 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0226 | 0.2251 | 0.2251 |
Plasmodium vivax | dipeptidyl aminopeptidase 3, putative | 0.0062 | 0.026 | 0.1155 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1444 | 0.1444 |
Schistosoma mansoni | subfamily C1A unassigned peptidase (C01 family) | 0.0062 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0181 | 0.0181 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.1067 | 0.268 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0128 | 0.1067 | 0.1067 |
Loa Loa (eye worm) | hypothetical protein | 0.0151 | 0.135 | 0.135 |
Leishmania major | cathepsin L-like protease | 0.0226 | 0.2251 | 0.6879 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.031 | 0.3272 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0162 | 0.1476 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0062 | 0.026 | 0.026 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0107 | 0.0812 | 0.0812 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0053 | 0.0053 |
Plasmodium falciparum | serine repeat antigen 3 | 0.0062 | 0.026 | 0.0273 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0151 | 0.135 | 0.135 |
Plasmodium vivax | unspecified product | 0.0066 | 0.0315 | 0.1401 |
Leishmania major | cathepsin L-like protease | 0.0226 | 0.2251 | 0.6879 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0062 | 0.026 | 0.026 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0092 | 0.0623 | 0.0623 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | fibroinase | 0.0226 | 0.2251 | 0.2251 |
Onchocerca volvulus | Cathepsin L homolog | 0.0226 | 0.2251 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0128 | 0.1067 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0226 | 0.2251 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.0623 | 0.0623 |
Brugia malayi | cathepsin L-like cysteine proteinase | 0.0062 | 0.026 | 0.026 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0233 | 0.2344 | 0.2344 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta-PAK, putative | 0.0043 | 0.0034 | 0.0034 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0128 | 0.1067 | 0.1067 |
Echinococcus multilocularis | cathepsin L | 0.0128 | 0.1067 | 0.1067 |
Brugia malayi | mbt repeat family protein | 0.0055 | 0.0181 | 0.0181 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0057 | 0.0204 | 0.0204 |
Echinococcus granulosus | cathepsin L | 0.0062 | 0.026 | 0.026 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0112 | 0.0871 | 0.0871 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0128 | 0.1067 | 0.4217 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0315 | 0.0315 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Brugia malayi | cahepsin L-like non-peptiedase homolog | 0.0062 | 0.026 | 0.026 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0128 | 0.1067 | 0.1067 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Leishmania major | cathepsin L-like protease | 0.0226 | 0.2251 | 0.6879 |
Brugia malayi | Protein kinase domain containing protein | 0.0057 | 0.0204 | 0.0204 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0063 | 0.0274 | 0.0274 |
Brugia malayi | Trypsin family protein | 0.0133 | 0.1126 | 0.1126 |
Onchocerca volvulus | 0.0062 | 0.026 | 0.0942 | |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0151 | 0.135 | 0.135 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1444 | 0.1444 |
Echinococcus granulosus | tumor protein p63 | 0.0392 | 0.4272 | 0.4272 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0053 | 0.0053 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0226 | 0.2251 | 0.2251 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0107 | 0.0812 | 0.0812 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0066 | 0.0315 | 0.0315 |
Onchocerca volvulus | 0.0133 | 0.1126 | 0.4882 | |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0315 | 0.0315 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.0292 | 0.0292 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Echinococcus granulosus | cathepsin b | 0.0863 | 1 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0128 | 0.1067 | 0.1067 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0226 | 0.2251 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Plasmodium falciparum | serine repeat antigen 9 | 0.0062 | 0.026 | 0.0273 |
Schistosoma mansoni | cathepsin C | 0.0062 | 0.026 | 0.026 |
Schistosoma mansoni | dipeptidyl-peptidase I (C01 family) | 0.0062 | 0.026 | 0.026 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0045 | 0.0053 | 0.0053 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0133 | 0.1126 | 0.1126 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0055 | 0.0181 | 0.0181 |
Onchocerca volvulus | 0.0067 | 0.032 | 0.1215 | |
Brugia malayi | Cathepsin L-like precursor | 0.0226 | 0.2251 | 0.2251 |
Loa Loa (eye worm) | hypothetical protein | 0.0125 | 0.1024 | 0.1024 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0292 | 0.0292 |
Onchocerca volvulus | 0.0055 | 0.0181 | 0.0581 | |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.0292 | 0.0292 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0128 | 0.1067 | 0.1067 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0057 | 0.0204 | 0.0204 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0062 | 0.026 | 0.026 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0066 | 0.0315 | 0.0315 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0066 | 0.0315 | 0.0315 |
Trypanosoma brucei | mitochondrial DNA polymerase beta | 0.0307 | 0.3245 | 0.9915 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0062 | 0.026 | 0.026 |
Echinococcus granulosus | cathepsin b | 0.0863 | 1 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.1067 | 0.3261 |
Loa Loa (eye worm) | hypothetical protein | 0.0863 | 1 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0128 | 0.1067 | 0.1067 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0057 | 0.0204 | 0.0907 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0128 | 0.1067 | 0.1067 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0292 | 0.0292 |
Toxoplasma gondii | cathepsin CPL | 0.0226 | 0.2251 | 0.677 |
Plasmodium vivax | serine-repeat antigen (SERA) | 0.0062 | 0.026 | 0.1155 |
Schistosoma mansoni | cathepsin B (C01 family) | 0.0062 | 0.026 | 0.026 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0226 | 0.2251 | 0.2251 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.0664 | 0.0664 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.08 | 0.9233 | 0.9233 |
Schistosoma mansoni | subfamily C1A non-peptidase homologue (C01 family) | 0.0062 | 0.026 | 0.026 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.026 | 0.026 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0151 | 0.135 | 0.5597 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0226 | 0.2251 | 0.2251 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.026 | 0.026 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0055 | 0.0181 | 0.0181 |
Loa Loa (eye worm) | cathepsin B | 0.031 | 0.3272 | 0.3272 |
Loa Loa (eye worm) | hypothetical protein | 0.0226 | 0.2251 | 0.2251 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0055 | 0.0181 | 0.0181 |
Onchocerca volvulus | Cathepsin F homolog | 0.0226 | 0.2251 | 1 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.0292 | 0.0292 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0623 | 0.0623 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.026 | 0.026 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0226 | 0.2251 | 0.2251 |
Schistosoma mansoni | cathepsin S (C01 family) | 0.0062 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.026 | 0.026 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0863 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.0226 | 0.2251 | 0.6879 |
Plasmodium falciparum | dipeptidyl aminopeptidase 1 | 0.0062 | 0.026 | 0.0273 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0226 | 0.2251 | 0.2251 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0226 | 0.2251 | 0.2251 |
Giardia lamblia | Cathepsin B precursor | 0.031 | 0.3272 | 1 |
Plasmodium vivax | serine-repeat antigen (SERA), putative | 0.0062 | 0.026 | 0.1155 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0159 | 0.1444 | 0.1444 |
Plasmodium vivax | serine-repeat antigen 2 (SERA) | 0.0062 | 0.026 | 0.1155 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.031 | 0.3272 | 0.3272 |
Brugia malayi | calpain family protein 1 | 0.0107 | 0.0812 | 0.0812 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0292 | 0.0292 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0226 | 0.2251 | 0.2251 |
Echinococcus multilocularis | cysteine protease | 0.0226 | 0.2251 | 0.2251 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0292 | 0.0292 |
Loa Loa (eye worm) | DEAH box polypeptide 35 | 0.0411 | 0.4504 | 0.4504 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0128 | 0.1067 | 0.3261 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0863 | 1 | 1 |
Plasmodium falciparum | dipeptidyl aminopeptidase 2 | 0.0062 | 0.026 | 0.0273 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Trypanosoma brucei | DNA polymerase beta thumb, putative | 0.0043 | 0.0034 | 0.0103 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0128 | 0.1067 | 0.268 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0151 | 0.135 | 0.3919 |
Brugia malayi | Trypsin family protein | 0.0045 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0053 | 0.0053 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Brugia malayi | hypothetical protein | 0.0233 | 0.2344 | 0.2344 |
Brugia malayi | Trypsin family protein | 0.0045 | 0.0053 | 0.0053 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0063 | 0.0274 | 0.0274 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0151 | 0.135 | 0.135 |
Brugia malayi | Cathepsin L-like precursor | 0.0159 | 0.1444 | 0.1444 |
Brugia malayi | Cathepsin L-like precursor | 0.0226 | 0.2251 | 0.2251 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.0812 | 0.0812 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0151 | 0.135 | 0.135 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Onchocerca volvulus | Cathepsin L homolog | 0.0226 | 0.2251 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.031 | 0.3272 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0205 | 0.0205 |
Onchocerca volvulus | 0.0057 | 0.0204 | 0.0687 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Echinococcus multilocularis | calpain family protein 1, d | 0.0079 | 0.0468 | 0.0468 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0066 | 0.0315 | 0.0315 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0226 | 0.2251 | 0.2251 |
Onchocerca volvulus | Huntingtin homolog | 0.0125 | 0.1024 | 0.4417 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0062 | 0.026 | 0.026 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0233 | 0.2344 | 0.2344 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0159 | 0.1444 | 0.393 |
Plasmodium vivax | vivapain-1 | 0.0128 | 0.1067 | 0.4741 |
Brugia malayi | Probable ATP-dependent helicase DHX35 | 0.0411 | 0.4504 | 0.4504 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0863 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0159 | 0.1444 | 0.1444 |
Echinococcus granulosus | family C2 unassigned peptidase C02 family | 0.0112 | 0.0871 | 0.0871 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0151 | 0.135 | 0.5473 |
Plasmodium vivax | RNA helicase-1, putative | 0.0151 | 0.135 | 0.5996 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.0292 | 0.0292 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0128 | 0.1067 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.0226 | 0.2251 | 0.2251 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0128 | 0.1067 | 0.4054 |
Onchocerca volvulus | 0.0226 | 0.2251 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0863 | 1 | 1 |
Brugia malayi | C2-HC type zinc finger protein C.e-MyT1 | 0.0063 | 0.0274 | 0.0274 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0055 | 0.0181 | 0.0181 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0055 | 0.0181 | 0.0581 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0151 | 0.135 | 0.4125 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0128 | 0.1067 | 0.1067 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0057 | 0.0205 | 0.0205 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0226 | 0.2251 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Plasmodium vivax | unspecified product | 0.0128 | 0.1067 | 0.4741 |
Trypanosoma cruzi | mitochondrial DNA polymerase beta, putative | 0.0307 | 0.3245 | 0.3245 |
Brugia malayi | cathepsin L precursor | 0.0062 | 0.026 | 0.026 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0062 | 0.026 | 0.026 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0057 | 0.0204 | 0.0204 |
Brugia malayi | Cathepsin L-like precursor | 0.0066 | 0.0315 | 0.0315 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0128 | 0.1067 | 0.1067 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0151 | 0.135 | 0.135 |
Entamoeba histolytica | cysteine protease, putative | 0.0226 | 0.2251 | 1 |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0034 | 0.0034 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0092 | 0.0623 | 0.0623 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Onchocerca volvulus | 0.0088 | 0.0581 | 0.2404 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0226 | 0.2251 | 0.661 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0045 | 0.0053 | 0.0053 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1126 | 0.1126 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0151 | 0.135 | 0.3618 |
Loa Loa (eye worm) | hypothetical protein | 0.0062 | 0.026 | 0.026 |
Loa Loa (eye worm) | hypothetical protein | 0.0233 | 0.2344 | 0.2344 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0045 | 0.0053 | 0.0053 |
Plasmodium falciparum | serine repeat antigen 5 | 0.0062 | 0.026 | 0.0273 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0053 | 0.0053 |
Echinococcus multilocularis | Mastin | 0.0045 | 0.0053 | 0.0053 |
Brugia malayi | RNA binding protein | 0.0064 | 0.0292 | 0.0292 |
Leishmania major | cathepsin L-like protease | 0.0226 | 0.2251 | 0.6879 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0053 | 0.0053 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0045 | 0.0053 | 0.0053 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0045 | 0.0053 | 0.0053 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0045 | 0.0053 | 0.0053 |
Onchocerca volvulus | 0.0226 | 0.2251 | 1 | |
Trypanosoma cruzi | DNA polymerase beta thumb, putative | 0.0043 | 0.0034 | 0.0034 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0226 | 0.2251 | 0.2251 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0062 | 0.026 | 0.026 |
Brugia malayi | cathepsin Z-like cysteine proteinase | 0.0062 | 0.026 | 0.026 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0151 | 0.135 | 0.4125 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0063 | 0.0274 | 0.0274 |
Echinococcus granulosus | cathepsin l1 | 0.0159 | 0.1444 | 0.1444 |
Plasmodium falciparum | serine repeat antigen 4 | 0.0062 | 0.026 | 0.0273 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0066 | 0.0315 | 0.0315 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0092 | 0.0623 | 0.0623 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0045 | 0.0053 | 0.0053 |
Leishmania major | cathepsin L-like protease | 0.0226 | 0.2251 | 0.6879 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0055 | 0.0181 | 0.0181 |
Onchocerca volvulus | 0.0226 | 0.2251 | 1 | |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0048 | 0.0087 | 0.0087 |
Plasmodium vivax | serine-repeat antigen 5 (SERA) | 0.0062 | 0.026 | 0.1155 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1444 | 0.1444 |
Entamoeba histolytica | cysteine protease, putative | 0.0128 | 0.1067 | 0.4054 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0112 | 0.0871 | 0.0871 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0226 | 0.2251 | 0.6879 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.1126 | 0.1126 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Reduction (functional) | = 23 % | Percent decrease in serum cholesterol (Cho) after 7 days at 0.05 percent in the diet of SD male rats in comparison to control animals | ChEMBL. | 3950914 |
Reduction (functional) | = 39 % | Percent decrease in triglyceride (TG) after 7 days at 0.05 percent in the diet of SD male rats in comparison to control animals | ChEMBL. | 3950914 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.