Detailed information for compound 202228

Basic information

Technical information
  • TDR Targets ID: 202228
  • Name: prop-1-ene
  • MW: 42.0797 | Formula: C3H6
  • H donors: 0 H acceptors: 0 LogP: 1.44 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC=C
  • InChi: 1S/C3H6/c1-3-2/h3H,1H2,2H3
  • InChiKey: QQONPFPTGQHPMA-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • 1-propene
  • propylene
  • Polypropylenes
  • 115-07-1
  • 33004-01-2
  • 676-63-1
  • c0067
  • 428116_ALDRICH
  • 427861_ALDRICH
  • 82222_FLUKA
  • 427888_ALDRICH
  • C11505
  • Propene
  • 1-Propylene
  • CCRIS 1356
  • EINECS 204-062-1
  • HSDB 175
  • Methylethene
  • Methylethylene
  • NCI-C50077
  • Propene, pure
  • Propylene see also Petroleum gases, liquefied [UN1077] [Flammable gas]
  • R 1270
  • UN1077
  • 452149_ALDRICH
  • CH2=CH-CH3
  • CHEBI:16052
  • 428183_ALDRICH
  • 427896_ALDRICH
  • 452157_ALDRICH
  • 565628_ALDRICH
  • Polypropylene, methyl-PSS nanoreinforced
  • Polipropene 25
  • Polypropylene, isotatic
  • 182389_ALDRICH
  • Polypropylene,isotactic
  • 1-Propene, homopolymer
  • 295663_ALDRICH
  • 428175_ALDRICH
  • 427853_ALDRICH
  • POLYPROPYLENE
  • 1-Propene, homopolymer, isotactic
  • InChI=1/C3H6/c1-3-2/h3H,1H2,2H

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0069 0.003
Loa Loa (eye worm) follicle stimulating hormone receptor 0.024 0.708 0.7069
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0034 0.0546 0.0509
Loa Loa (eye worm) hypothetical protein 0.0041 0.078 0.0744
Brugia malayi Succinate semialdehyde dehydrogenase, mitochondrial precursor 0.0041 0.078 0.078
Mycobacterium ulcerans hypothetical protein 0.0028 0.0366 0.0337
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxM_2 0.0059 0.133 0.1428
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.1748 0.4656
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0041 0.078 0.0806
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0132 0.3676 1
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.0023 0.0217 0.0167
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0132 0.3676 0.3676
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0034 0.0546 0.0572
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0041 0.078 0.0744
Loa Loa (eye worm) hypothetical protein 0.0034 0.0546 0.0509
Trichomonas vaginalis aldehyde oxidase, putative 0.0174 0.4979 0.5559
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0082 0.2068 0.2263
Loa Loa (eye worm) steroid hormone receptor 0.0034 0.0546 0.0509
Loa Loa (eye worm) hypothetical protein 0.0034 0.0546 0.0509
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.0264 0.7836 0.7836
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0546 0.0509
Loa Loa (eye worm) hypothetical protein 0.003 0.043 0.0392
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.0023 0.0217 0.5
Treponema pallidum hypothetical protein 0.0023 0.0208 0.4689
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0129 0.3569 0.3544
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0034 0.0546 0.0572
Echinococcus multilocularis transcription factor Dp 1 0.0042 0.0789 0.0753
Echinococcus granulosus Aminotransferase class III 0.0023 0.0217 0.0178
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0069 0.0069
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0546 0.0546
Mycobacterium ulcerans carbon monoxyde dehydrogenase large chain CoxL 0.0051 0.1104 0.1172
Loa Loa (eye worm) IRE protein kinase 0.0332 1 1
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0546 0.0546
Schistosoma mansoni ap endonuclease 0.0019 0.0069 0.0034
Echinococcus multilocularis carbonic anhydrase 0.003 0.043 0.0392
Loa Loa (eye worm) hypothetical protein 0.0034 0.0546 0.0509
Mycobacterium leprae PROBABLE SUCCINATE-SEMIALDEHYDE DEHYDROGENASE [NADP+] DEPENDENT (SSDH) GABD 0.0041 0.078 1
Onchocerca volvulus 0.0034 0.0546 0.5
Brugia malayi hypothetical protein 0.0018 0.0039 0.0039
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.003 0.043 0.043
Echinococcus multilocularis nuclear factor of activated T cells 5 0.008 0.2011 0.198
Echinococcus multilocularis carbonic anhydrase II 0.0132 0.3676 0.3651
Schistosoma mansoni carbonic anhydrase-related 0.003 0.043 0.0441
Toxoplasma gondii hypothetical protein 0.003 0.043 0.0652
Loa Loa (eye worm) glutaminase 0.0297 0.8901 0.8897
Brugia malayi photoreceptor-specific nuclear receptor 0.0034 0.0546 0.0546
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0034 0.0546 0.0509
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.003 0.043 0.043
Schistosoma mansoni aldehyde dehydrogenase 0.0193 0.5606 0.6282
Mycobacterium ulcerans succinate-semialdehyde dehydrogenase 0.0041 0.078 0.0806
Schistosoma mansoni carbonic anhydrase-related 0.003 0.043 0.0441
Schistosoma mansoni coup transcription factor 0.0034 0.0546 0.0572
Loa Loa (eye worm) hypothetical protein 0.0034 0.0546 0.0509
Schistosoma mansoni succinate semialdehyde dehydrogenase 0.0041 0.078 0.0837
Schistosoma mansoni serine/threonine protein kinase 0.017 0.4869 0.5451
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.0023 0.0217 0.0167
Echinococcus multilocularis thyroid hormone receptor alpha 0.0034 0.0546 0.0509
Echinococcus granulosus transcription factor Dp 1 0.0042 0.0789 0.0753
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0023 0.0217 0.019
Plasmodium falciparum ornithine aminotransferase 0.0023 0.0217 0.4095
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.0023 0.0217 0.0267
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.0264 0.7836 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0034 0.0546 0.0546
Loa Loa (eye worm) carbonic anhydrase 3 0.0132 0.3676 0.3651
Mycobacterium ulcerans aerobic-type carbon monoxide dehydrogenase subunit CoxL_2 0.0082 0.2068 0.2263
Schistosoma mansoni ap endonuclease 0.0019 0.0069 0.0034
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0034 0.0546 0.0572
Brugia malayi steroid hormone receptor 0.0034 0.0546 0.0546
Toxoplasma gondii NADP-dependent succinate-semialdehyde dehydrogenase 0.0041 0.078 0.1285
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0034 0.0546 0.0546
Plasmodium vivax ornithine aminotransferase, putative 0.0023 0.0217 1
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0072 0.1748 0.1691
Schistosoma mansoni aldehyde dehydrogenase 0.0193 0.5606 0.6282
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0174 0.4979 0.5559
Mycobacterium tuberculosis Probable aminotransferase 0.0023 0.0217 0.019
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.0023 0.0217 0.019
Echinococcus multilocularis succinate semialdehyde dehydrogenase 0.0041 0.078 0.0744
Treponema pallidum quinoline 2-oxidoreductase 0.0028 0.0346 0.93
Echinococcus granulosus succinate semialdehyde dehydrogenase 0.0041 0.078 0.0744
Mycobacterium ulcerans carbon monoxyde dehydrogenase medium chain CoxM 0.0059 0.133 0.1428
Trichomonas vaginalis serine threonine-protein kinase, putative 0.0169 0.4836 0.5398
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0069 0.003
Echinococcus granulosus ornithine aminotransferase 0.0023 0.0217 0.0178
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0034 0.0546 0.0509
Loa Loa (eye worm) hypothetical protein 0.0034 0.0546 0.0509
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0069 0.003
Echinococcus granulosus carbonic anhydrase 0.003 0.043 0.0392
Echinococcus granulosus serine:threonine protein kinase:endoribonuclease 0.0332 1 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0034 0.0546 0.0509
Echinococcus granulosus nuclear factor of activated T cells 5 0.008 0.2011 0.198
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0193 0.5606 1
Trichomonas vaginalis glutaminase, putative 0.0297 0.8901 1
Echinococcus granulosus carbonic anhydrase 0.003 0.043 0.0392
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0034 0.0546 0.0509
Echinococcus multilocularis carbonic anhydrase 0.003 0.043 0.0392
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.0023 0.0217 0.019
Mycobacterium ulcerans carbon monoxide dehydrogenase 0.0115 0.3119 0.3454
Loa Loa (eye worm) hypothetical protein 0.0034 0.0546 0.0509
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0034 0.0546 0.0546
Echinococcus granulosus FTZ F1 alpha 0.0034 0.0546 0.0509
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0132 0.3676 0.3651
Loa Loa (eye worm) hypothetical protein 0.003 0.043 0.0392
Entamoeba histolytica protein kinase, putative 0.0332 1 1
Echinococcus granulosus ecdysone induced protein 78C 0.0034 0.0546 0.0509
Schistosoma mansoni ornithine--oxo-acid transaminase 0.0023 0.0217 0.02
Leishmania major carbonic anhydrase-like protein 0.0132 0.3676 0.6514
Leishmania major aldehyde dehydrogenase, putative 0.0041 0.078 0.1285
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0034 0.0546 0.0546
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0039 0.0039
Trichomonas vaginalis xanthine dehydrogenase, putative 0.0174 0.4979 0.5559
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0034 0.0546 0.0509
Trichomonas vaginalis conserved hypothetical protein 0.0169 0.4836 0.5398
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0034 0.0546 0.0546
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0023 0.0217 0.0167
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0546 0.0509
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0034 0.0546 0.0572
Brugia malayi Nuclear hormone receptor-like 1 0.0018 0.0039 0.0039
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0132 0.3676 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0072 0.1748 0.1716
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0034 0.0546 0.0509
Echinococcus multilocularis ornithine aminotransferase 0.0023 0.0217 0.0178
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0034 0.0546 0.0546
Brugia malayi nuclear receptor RXR 0.0018 0.0039 0.0039
Loa Loa (eye worm) hypothetical protein 0.0034 0.0546 0.0509
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0072 0.1748 0.1929
Schistosoma mansoni nuclear hormone receptor 0.0034 0.0546 0.0572
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0034 0.0546 0.0546
Trypanosoma cruzi aldehyde dehydrogenase, putative 0.0041 0.078 0.1973
Mycobacterium ulcerans aldehyde dehydrogenase 0.0193 0.5606 0.6269
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0072 0.1748 0.3033
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0034 0.0546 0.5
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0069 0.5
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0023 0.0217 0.0167
Echinococcus granulosus carbonic anhydrase II 0.0132 0.3676 0.3651
Treponema pallidum hypothetical protein 0.0028 0.0366 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0034 0.0546 0.0509
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0034 0.0546 0.0509
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0132 0.3676 0.4104
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0193 0.5606 0.5589
Mycobacterium ulcerans aldehyde dehydrogenase 0.0193 0.5606 0.6269
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0034 0.0546 0.0509
Brugia malayi follicle stimulating hormone receptor 0.024 0.708 0.708
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 0.0041 0.078 0.0916
Schistosoma mansoni retinoic acid receptor RXR 0.0129 0.3569 0.3983
Mycobacterium ulcerans NAD-dependent aldehyde dehydrogenase AldA 0.0041 0.078 0.0806
Mycobacterium ulcerans acetylornithine aminotransferase 0.0023 0.0217 0.0167
Brugia malayi hypothetical protein 0.0018 0.0039 0.0039
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.003 0.043 0.043
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.0023 0.0217 0.019
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0193 0.5606 0.7128
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0033 0.0523 0.0514
Onchocerca volvulus Bile acid receptor homolog 0.0034 0.0546 0.5
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0546 0.0572
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0072 0.1748 0.1748
Entamoeba histolytica protein kinase, putative 0.0332 1 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0546 0.0509
Mycobacterium tuberculosis Probable aldehyde dehydrogenase NAD dependent AldA (aldehyde dehydrogenase [NAD+]) 0.0041 0.078 0.0916
Echinococcus multilocularis ornithine aminotransferase 0.0023 0.0217 0.0178
Echinococcus multilocularis serine:threonine protein kinase:endoribonuclease 0.0332 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0034 0.0546 0.0509
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0132 0.3676 0.4104
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (large chain) 0.0082 0.2068 0.2573
Loa Loa (eye worm) glutaminase 2 0.0297 0.8901 0.8897
Brugia malayi Nuclear hormone receptor-like 1 0.0034 0.0546 0.0546
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0023 0.0217 0.0167
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (small chain) 0.0033 0.0523 0.0584
Brugia malayi Steroid receptor seven-up type 2 0.0034 0.0546 0.0546
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0034 0.0546 0.0509
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0034 0.0546 0.0546
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.1748 0.4656
Brugia malayi nuclear receptor NHR-88 0.0034 0.0546 0.0546
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0546 0.0546
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.003 0.043 0.043
Schistosoma mansoni steroid hormone receptor ad4bp 0.0034 0.0546 0.0572
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0072 0.1748 0.4656
Brugia malayi ecdysteroid receptor 0.0034 0.0546 0.0546
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.0023 0.0217 0.0167
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0193 0.5606 0.5589
Mycobacterium ulcerans aldehyde dehydrogenase 0.0193 0.5606 0.6269
Echinococcus multilocularis carbonic anhydrase 0.003 0.043 0.0392
Trypanosoma brucei aldehyde dehydrogenase, putative 0.0041 0.078 0.1973
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0034 0.0546 0.0572
Schistosoma mansoni carbonic anhydrase-related 0.003 0.043 0.0441
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0111 0.3001 0.2974
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0034 0.0546 0.0546
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0034 0.0546 0.0509
Echinococcus granulosus carbonic anhydrase 0.003 0.043 0.0392
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.003 0.043 0.043
Loa Loa (eye worm) hypothetical protein 0.0041 0.078 0.0744
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0034 0.0546 0.0509
Onchocerca volvulus Protein ultraspiracle homolog 0.0034 0.0546 0.5
Echinococcus multilocularis ecdysone induced protein 78C 0.0034 0.0546 0.0509
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0034 0.0546 0.0572
Brugia malayi glutaminase DH11.1 0.0297 0.8901 0.8901
Schistosoma mansoni hypothetical protein 0.003 0.043 0.0441
Schistosoma mansoni RAR-like nuclear receptor 0.0034 0.0546 0.0572
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0034 0.0546 0.0509
Brugia malayi nuclear hormone receptor 0.0034 0.0546 0.0546
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.003 0.043 0.0392
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0132 0.3676 0.3676
Mycobacterium tuberculosis Probable carbon monoxyde dehydrogenase (medium chain) 0.0059 0.133 0.1624
Schistosoma mansoni thyroid hormone receptor 0.0034 0.0546 0.0572
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0072 0.1748 0.1716
Plasmodium falciparum carbonic anhydrase 0.003 0.043 1
Schistosoma mansoni carbonic anhydrase 0.003 0.043 0.0441
Mycobacterium ulcerans hypothetical protein 0.0023 0.0217 0.0167
Schistosoma mansoni glutaminase 0.0297 0.8901 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0034 0.0546 0.0509
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0072 0.1748 0.1716
Loa Loa (eye worm) hypothetical protein 0.003 0.043 0.0392
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0034 0.0546 0.0546
Mycobacterium ulcerans carbon monoxyde dehydrogenase small chain CoxS 0.0033 0.0523 0.0514
Echinococcus multilocularis FTZ F1 alpha 0.0034 0.0546 0.0509
Toxoplasma gondii aldehyde dehydrogenase 0.0193 0.5606 1
Mycobacterium ulcerans glutaminase 0.0297 0.8901 1
Mycobacterium ulcerans L-lysine aminotransferase 0.0264 0.7836 0.8794
Trypanosoma brucei carbonic anhydrase-like protein 0.0132 0.3676 1
Echinococcus multilocularis Aminotransferase class III 0.0023 0.0217 0.0178
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.0023 0.0217 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0034 0.0546 0.0509

Activities

Activity type Activity value Assay description Source Reference
logP (ADMET) = 1.77 Partition coefficient (logP) ChEMBL. 3882967

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

5 literature references were collected for this gene.

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