Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Schistosoma mansoni | heat shock protein | 0.0033 | 0.0589 | 0.0589 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0065 | 0.1767 | 0.5715 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0074 | 0.2102 | 0.2102 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.1367 | 0.3723 |
Loa Loa (eye worm) | cathepsin B | 0.0101 | 0.3093 | 0.3093 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0039 | 0.0813 | 0.5946 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.0589 | 0.0589 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Giardia lamblia | Cathepsin B precursor | 0.0101 | 0.3093 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.0054 | 0.1367 | 1 |
Schistosoma mansoni | cgmp-dependent 35-cyclic phosphodiesterase | 0.0033 | 0.0582 | 0.0582 |
Schistosoma mansoni | endoplasmin | 0.0033 | 0.0589 | 0.0589 |
Brugia malayi | 3'5'-cyclic nucleotide phosphodiesterase family protein | 0.0033 | 0.0582 | 0.0582 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0033 | 0.0589 | 0.0138 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Onchocerca volvulus | 0.0054 | 0.1367 | 1 | |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Echinococcus granulosus | heat shock protein 90 | 0.0033 | 0.0589 | 0.0589 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0054 | 0.1367 | 0.1367 |
Treponema pallidum | heat shock protein 90 | 0.0026 | 0.0343 | 0.5 |
Trichomonas vaginalis | cAMP/cGMP cyclic nucleotide phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Onchocerca volvulus | 0.0054 | 0.1367 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0039 | 0.0813 | 0.0813 |
Echinococcus multilocularis | dual 3',5' cyclic AMP and GMP phosphodiesterase | 0.0074 | 0.2102 | 0.2102 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0288 | 1 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.0589 | 0.0589 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0074 | 0.2102 | 0.6796 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0054 | 0.1367 | 0.1367 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0054 | 0.1367 | 0.1367 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.0813 | 0.2627 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0033 | 0.0589 | 0.1904 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0065 | 0.1767 | 0.5715 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.1367 | 0.1367 |
Onchocerca volvulus | 0.0054 | 0.1367 | 1 | |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0589 | 0.0138 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.005 | 0.1235 | 0.3994 |
Giardia lamblia | Grp94/Hsp90 | 0.0026 | 0.0343 | 0.1109 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0026 | 0.0343 | 0.0343 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.005 | 0.1235 | 0.1235 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.0026 | 0.0343 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0054 | 0.1367 | 0.1367 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0074 | 0.2102 | 0.6096 |
Plasmodium vivax | heat shock protein 86, putative | 0.0033 | 0.0589 | 0.431 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0054 | 0.1367 | 1 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0033 | 0.0582 | 0.1883 |
Toxoplasma gondii | hypothetical protein | 0.0023 | 0.0248 | 0.0802 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0054 | 0.1367 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Giardia lamblia | Cathepsin B precursor | 0.0101 | 0.3093 | 1 |
Toxoplasma gondii | cathepsin B | 0.0101 | 0.3093 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0065 | 0.1767 | 0.5715 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0343 | 0.1109 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.1367 | 0.1367 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0074 | 0.2102 | 0.2102 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0813 | 0.0813 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0033 | 0.0589 | 0.1904 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.1367 | 0.3723 |
Loa Loa (eye worm) | endoplasmin | 0.0033 | 0.0589 | 0.0589 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Echinococcus granulosus | dual 3'5' cyclic AMP and GMP phosphodiesterase | 0.0074 | 0.2102 | 0.2102 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0033 | 0.0589 | 0.431 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0813 | 0.0813 |
Trichomonas vaginalis | heat shock protein, putative | 0.002 | 0.0122 | 0.0395 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0033 | 0.0589 | 0.0589 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0582 | 0.0582 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0033 | 0.0589 | 0.1904 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Echinococcus multilocularis | cathepsin b | 0.0288 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0054 | 0.1367 | 0.1367 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0032 | 0.0554 | 0.0554 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Plasmodium falciparum | endoplasmin, putative | 0.002 | 0.0122 | 0.0894 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Onchocerca volvulus | 0.0054 | 0.1367 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0039 | 0.0813 | 0.2627 |
Echinococcus granulosus | cathepsin b | 0.0288 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0032 | 0.0554 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0343 | 0.1109 |
Toxoplasma gondii | cathepsin CPL | 0.0054 | 0.1367 | 0.4419 |
Mycobacterium ulcerans | heat shock protein 90 | 0.0026 | 0.0343 | 0.3862 |
Trichomonas vaginalis | endoplasmin, putative | 0.002 | 0.0122 | 0.0395 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0248 | 0.0248 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0589 | 0.0138 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0032 | 0.0554 | 0.4054 |
Echinococcus granulosus | cathepsin l1 | 0.0054 | 0.1367 | 0.1367 |
Echinococcus multilocularis | heat shock protein | 0.0033 | 0.0589 | 0.0589 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Onchocerca volvulus | 0.0054 | 0.1367 | 1 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0023 | 0.0248 | 0.1815 |
Trypanosoma brucei | cAMP-specific phosphodiesterase | 0.0074 | 0.2102 | 0.6096 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.1367 | 0.3723 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Onchocerca volvulus | Cathepsin L homolog | 0.0054 | 0.1367 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0054 | 0.1367 | 0.1367 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0039 | 0.0813 | 0.0813 |
Echinococcus granulosus | endoplasmin | 0.0026 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1367 | 0.1367 |
Toxoplasma gondii | hypothetical protein | 0.0065 | 0.1767 | 0.5715 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0032 | 0.0554 | 0.0554 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Onchocerca volvulus | 0.0054 | 0.1367 | 1 | |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0054 | 0.1367 | 0.1367 |
Plasmodium falciparum | heat shock protein 90 | 0.0033 | 0.0589 | 0.431 |
Leishmania major | cysteine peptidase A (CPA) | 0.0054 | 0.1367 | 0.3723 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0032 | 0.0554 | 0.0554 |
Brugia malayi | Endoplasmin precursor | 0.0033 | 0.0589 | 0.0589 |
Echinococcus granulosus | cathepsin l1 | 0.0039 | 0.0813 | 0.0813 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.1367 | 0.3723 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0054 | 0.1367 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0101 | 0.3093 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0054 | 0.1367 | 0.1367 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0033 | 0.0589 | 0.0589 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0589 | 0.0138 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0054 | 0.1367 | 0.1367 |
Brugia malayi | Cathepsin L-like precursor | 0.0039 | 0.0813 | 0.0813 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.1367 | 0.1367 |
Entamoeba histolytica | cysteine protease, putative | 0.0054 | 0.1367 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Brugia malayi | heat shock protein 90 | 0.0033 | 0.0589 | 0.0589 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0032 | 0.0554 | 0.1791 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Plasmodium vivax | endoplasmin, putative | 0.0033 | 0.0589 | 0.431 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0101 | 0.3093 | 0.3093 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0054 | 0.1367 | 0.1367 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0026 | 0.0343 | 0.1109 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0054 | 0.1367 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0054 | 0.1367 | 0.1367 |
Echinococcus multilocularis | heat shock protein 90 | 0.0033 | 0.0589 | 0.0589 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0033 | 0.0589 | 0.0589 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Echinococcus granulosus | heat shock protein | 0.0033 | 0.0589 | 0.0589 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0032 | 0.0554 | 0.4054 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0589 | 0.0138 |
Echinococcus multilocularis | cAMP and cAMP inhibited cGMP 3',5' cyclic | 0.0033 | 0.0582 | 0.0582 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0033 | 0.0589 | 0.0589 |
Mycobacterium ulcerans | two component sensor histidine kinase DevS | 0.003 | 0.0494 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0033 | 0.0589 | 0.0138 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0288 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0054 | 0.1367 | 1 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0033 | 0.0582 | 0.1883 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0032 | 0.0554 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0032 | 0.0554 | 0.0554 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0032 | 0.0554 | 0.0554 |
Echinococcus granulosus | cysteine protease | 0.0032 | 0.0554 | 0.0554 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0032 | 0.0554 | 0.0554 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0101 | 0.3093 | 0.3093 |
Trichomonas vaginalis | cGMP-inhibited 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Schistosoma mansoni | camp/cgmp cyclic nucleotide phosphodiesterase | 0.0074 | 0.2102 | 0.2102 |
Echinococcus multilocularis | heat shock protein 90 | 0.0026 | 0.0343 | 0.0343 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0032 | 0.0554 | 0.0554 |
Echinococcus multilocularis | endoplasmin | 0.0026 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0813 | 0.0813 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.0026 | 0.0343 | 0.5 |
Echinococcus granulosus | heat shock protein 90 | 0.0026 | 0.0343 | 0.0343 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0288 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Plasmodium vivax | vivapain-1 | 0.0032 | 0.0554 | 0.4054 |
Plasmodium vivax | vivapain-3 | 0.0032 | 0.0554 | 0.4054 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Plasmodium vivax | unspecified product | 0.0032 | 0.0554 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0288 | 1 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0589 | 0.0138 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0023 | 0.0248 | 0.0802 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Toxoplasma gondii | hypothetical protein | 0.0023 | 0.0248 | 0.0802 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Plasmodium falciparum | GAF domain-related protein, putative | 0.0023 | 0.0248 | 0.1815 |
Trypanosoma cruzi | cAMP specific phosphodiesterase, putative | 0.0074 | 0.2102 | 0.2102 |
Trichomonas vaginalis | cAMP-specific phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0032 | 0.0554 | 0.0554 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0032 | 0.0554 | 0.0554 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Echinococcus granulosus | cathepsin b | 0.0288 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0054 | 0.1367 | 0.1367 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Trichomonas vaginalis | high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Toxoplasma gondii | GAF domain-containing protein | 0.0023 | 0.0248 | 0.0802 |
Plasmodium vivax | vivapain-2 | 0.0054 | 0.1367 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0039 | 0.0813 | 0.0813 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0033 | 0.0589 | 0.431 |
Trichomonas vaginalis | cAMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Trichomonas vaginalis | cone cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Brugia malayi | Cathepsin L-like precursor | 0.0039 | 0.0813 | 0.0813 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0026 | 0.0343 | 0.0343 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0054 | 0.1367 | 1 |
Trichomonas vaginalis | cyclic nucleotide phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Loa Loa (eye worm) | ctsf protein | 0.0054 | 0.1367 | 0.1367 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0032 | 0.0554 | 0.0554 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0101 | 0.3093 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0033 | 0.0589 | 0.0138 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DosT | 0.003 | 0.0494 | 1 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.1367 | 0.3723 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0288 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0288 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.1367 | 0.1367 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0101 | 0.3093 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0589 | 0.0138 |
Plasmodium vivax | vivapain-2 | 0.0054 | 0.1367 | 1 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative | 0.0033 | 0.0582 | 0.0582 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0054 | 0.1367 | 0.1367 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0589 | 0.0138 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0032 | 0.0554 | 0.1791 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Brugia malayi | cathepsin L-like precursor | 0.0039 | 0.0813 | 0.0813 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Echinococcus multilocularis | cysteine protease | 0.0054 | 0.1367 | 0.1367 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0101 | 0.3093 | 1 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.1367 | 0.3723 |
Trypanosoma brucei | heat shock protein, putative | 0.0033 | 0.0589 | 0.0138 |
Trichomonas vaginalis | cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0054 | 0.1367 | 0.1367 |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0032 | 0.0554 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Schistosoma mansoni | heat shock protein | 0.0033 | 0.0589 | 0.0589 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0032 | 0.0554 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Echinococcus granulosus | cathepsin L | 0.0032 | 0.0554 | 0.0554 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0054 | 0.1367 | 0.3201 |
Trichomonas vaginalis | cGMP-dependent 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Trichomonas vaginalis | cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative | 0.005 | 0.1235 | 0.3994 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0054 | 0.1367 | 0.1367 |
Mycobacterium tuberculosis | Two component sensor histidine kinase DevS | 0.003 | 0.0494 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0288 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0033 | 0.0589 | 0.0894 |
Echinococcus multilocularis | cathepsin L | 0.0032 | 0.0554 | 0.0554 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0054 | 0.1367 | 0.1367 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Trichomonas vaginalis | rod cGMP-specific 3,5-cyclic phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Schistosoma mansoni | endoplasmin | 0.0033 | 0.0589 | 0.0589 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0074 | 0.2102 | 0.6796 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.1367 | 0.3723 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.0026 | 0.0343 | 0.0343 |
Leishmania major | cathepsin L-like protease | 0.0054 | 0.1367 | 0.3723 |
Trichomonas vaginalis | heat shock protein, putative | 0.0033 | 0.0589 | 0.1904 |
Echinococcus multilocularis | cysteine protease | 0.0054 | 0.1367 | 0.1367 |
Trichomonas vaginalis | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative | 0.0033 | 0.0582 | 0.1883 |
Echinococcus granulosus | cAMP and cAMP inhibited cGMP 3'5' cyclic | 0.0033 | 0.0582 | 0.0582 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.1367 | 0.1367 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0054 | 0.1367 | 0.4419 |
Loa Loa (eye worm) | cysteine protease | 0.0054 | 0.1367 | 0.1367 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0019 | 0.0094 | 0.0094 |
Onchocerca volvulus | 0.0054 | 0.1367 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.0032 | 0.0554 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0032 | 0.0554 | 0.4054 |
Trypanosoma cruzi | cysteine protease, putative | 0.0032 | 0.0554 | 0.0554 |
Onchocerca volvulus | 0.0039 | 0.0813 | 0.5946 | |
Loa Loa (eye worm) | fibroinase | 0.0054 | 0.1367 | 0.1367 |
Trichomonas vaginalis | heat shock protein, putative | 0.0026 | 0.0343 | 0.1109 |
Brugia malayi | Cathepsin L-like precursor | 0.0054 | 0.1367 | 0.1367 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (binding) | = 0.11 uM | Inhibitory activity against phosphodiesterase 5 from human platelets | ChEMBL. | 7658441 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.