Detailed information for compound 2068776

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 331.393 | Formula: C15H17N5O2S
  • H donors: 0 H acceptors: 3 LogP: 0.99 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: C1CN(CC(O1)Cn1cncn1)Cc1coc(n1)c1cccs1
  • InChi: 1S/C15H17N5O2S/c1-2-14(23-5-1)15-18-12(9-22-15)6-19-3-4-21-13(7-19)8-20-11-16-10-17-20/h1-2,5,9-11,13H,3-4,6-8H2
  • InChiKey: MDHOSKMCTBCTFF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0016 0.0368 0.1086
Onchocerca volvulus 0.0008 0.0114 0.019
Trypanosoma cruzi metacaspase, putative 0.0017 0.0399 0.0375
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Mycobacterium tuberculosis Conserved protein 0.0016 0.0368 0.1086
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0017 0.0399 0.0624
Echinococcus multilocularis lamin 0.0011 0.0195 0.018
Loa Loa (eye worm) isocitrate dehydrogenase 0.0005 0.0026 0.0026
Echinococcus granulosus phd:f box containing protein 0.0006 0.0049 0.0035
Plasmodium vivax unspecified product 0.0041 0.1206 0.1972
Loa Loa (eye worm) MH2 domain-containing protein 0.0086 0.2683 0.2683
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0063 0.1914 0.1902
Brugia malayi cathepsin L precursor 0.0041 0.1206 0.1206
Brugia malayi Papain family cysteine protease containing protein 0.0101 0.3155 0.3155
Giardia lamblia Cysteine protease 0.0041 0.1206 0.2853
Giardia lamblia Hypothetical protein 0.0041 0.1206 0.2853
Mycobacterium tuberculosis Probable hydrolase 0.0016 0.0368 0.1086
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0309 1 1
Trypanosoma brucei metacaspase MCA2 0.0017 0.0399 0.0624
Mycobacterium tuberculosis Probable esterase LipL 0.0016 0.0368 0.1086
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.3155 0.515
Onchocerca volvulus 0.0011 0.0195 0.0324
Brugia malayi beta-lactamase 0.0016 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0041 0.1206 0.1206
Brugia malayi Cathepsin L-like precursor 0.0129 0.4065 0.4065
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0029 0.0784 0.0771
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0023 0.0606 0.0592
Loa Loa (eye worm) hypothetical protein 0.0008 0.0114 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0399 0.0473
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0124 0.3926 0.3911
Echinococcus multilocularis Protein lozenge 0.0022 0.0564 0.055
Giardia lamblia Cathepsin B precursor 0.0041 0.1206 0.2853
Leishmania major cathepsin L-like protease 0.0188 0.6014 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.1206 0.1184
Brugia malayi Smad1 0.0006 0.004 0.004
Onchocerca volvulus 0.0188 0.6014 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0188 0.0188
Brugia malayi Intermediate filament tail domain containing protein 0.0011 0.0195 0.0195
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0005 0.0025 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0016 0.0368 0.0344
Brugia malayi cathepsin L-like cysteine proteinase 0.0041 0.1206 0.1206
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0188 0.6014 1
Echinococcus multilocularis cysteine protease 0.0188 0.6014 0.6008
Brugia malayi Cathepsin L-like cysteine proteinase 0.0129 0.4065 0.4065
Giardia lamblia Hypothetical protein 0.0041 0.1206 0.2853
Brugia malayi MH1 domain containing protein 0.0006 0.004 0.004
Toxoplasma gondii HEAT repeat-containing protein 0.0011 0.0219 0.0323
Loa Loa (eye worm) jmjC domain-containing protein 0.0006 0.0049 0.0049
Brugia malayi RNA binding protein 0.0022 0.0564 0.0564
Loa Loa (eye worm) latrophilin receptor protein 2 0.0005 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Loa Loa (eye worm) hypothetical protein 0.0174 0.5566 0.5566
Plasmodium falciparum serine repeat antigen 5 0.0041 0.1206 0.1972
Brugia malayi Latrophilin receptor protein 2 0.0005 0.0025 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0017 0.0399 0.0473
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Leishmania major cathepsin L-like protease 0.0188 0.6014 1
Loa Loa (eye worm) beta-lactamase 0.0016 0.0368 0.0368
Schistosoma mansoni phd/f-box containing protein 0.0006 0.0049 0.0024
Loa Loa (eye worm) hypothetical protein 0.0129 0.4065 0.4065
Echinococcus multilocularis phd:f box containing protein 0.0006 0.0049 0.0035
Brugia malayi MH2 domain containing protein 0.0086 0.2683 0.2683
Plasmodium falciparum cysteine proteinase falcipain 3 0.0188 0.6014 1
Brugia malayi cathepsin L-like precursor 0.0129 0.4065 0.4065
Mycobacterium tuberculosis Probable lipase LipE 0.0016 0.0368 0.1086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0041 0.1206 0.1843
Loa Loa (eye worm) jmjC domain-containing protein 0.0006 0.0049 0.0049
Entamoeba histolytica cysteine protease, putative 0.0041 0.1206 0.1843
Entamoeba histolytica hypothetical protein 0.0029 0.0784 0.1126
Brugia malayi Cathepsin L-like precursor 0.0188 0.6014 0.6014
Loa Loa (eye worm) hypothetical protein 0.0041 0.1206 0.1206
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0007 0.0069 0.0055
Onchocerca volvulus 0.0008 0.0114 0.019
Schistosoma mansoni cathepsin F (C01 family) 0.0188 0.6014 0.6003
Loa Loa (eye worm) hypothetical protein 0.0009 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0016 0.0368 0.0368
Plasmodium vivax plasmepsin IV, putative 0.0009 0.0136 0.0184
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0041 0.1206 0.1843
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0017 0.0399 0.0473
Echinococcus multilocularis snurportin 1 0.0121 0.3821 0.3812
Schistosoma mansoni cathepsin D (A01 family) 0.0026 0.0699 0.0676
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Onchocerca volvulus 0.0129 0.4065 0.6759
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.3155 0.515
Echinococcus granulosus TGF beta signal transducer SmadC 0.0006 0.004 0.0025
Schistosoma mansoni lamin 0.0011 0.0195 0.017
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Brugia malayi jmjC domain containing protein 0.0006 0.0049 0.0049
Echinococcus multilocularis geminin 0.0219 0.7048 0.7043
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0017 0.0399 0.0473
Entamoeba histolytica cysteine proteinase, putative 0.0188 0.6014 1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0124 0.3926 0.3911
Echinococcus granulosus intermediate filament protein 0.0011 0.0195 0.018
Schistosoma mansoni hypothetical protein 0.0012 0.0233 0.0208
Brugia malayi isocitrate dehydrogenase 0.0005 0.0026 0.0026
Onchocerca volvulus 0.0188 0.6014 1
Brugia malayi Cathepsin L-like precursor 0.0059 0.1795 0.1795
Brugia malayi Papain family cysteine protease containing protein 0.0101 0.3155 0.3155
Trichomonas vaginalis importin beta-1, putative 0.0009 0.0148 0.0047
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0017 0.0399 0.0473
Loa Loa (eye worm) hypothetical protein 0.0011 0.0195 0.0195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Mycobacterium tuberculosis Probable lipase LipD 0.0016 0.0368 0.1086
Loa Loa (eye worm) hypothetical protein 0.0059 0.1795 0.1795
Trypanosoma cruzi metacaspase, putative 0.0017 0.0399 0.0375
Trypanosoma cruzi metacaspase, putative 0.0017 0.0399 0.0375
Trypanosoma brucei importin beta-1 subunit, putative 0.0011 0.0219 0.0323
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0033 0.0942 0.0928
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0041 0.1206 0.1972
Entamoeba histolytica cysteine proteinase 2 0.0101 0.3155 0.515
Echinococcus multilocularis cysteine protease 0.0188 0.6014 0.6008
Giardia lamblia Cathepsin B precursor 0.0124 0.3926 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0188 0.6014 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0016 0.0368 0.042
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0008 0.0121 0.0121
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0188 0.6014 0.6014
Plasmodium falciparum ataxin-2 like protein, putative 0.0009 0.0132 0.0178
Entamoeba histolytica cysteine protease, putative 0.0041 0.1206 0.1843
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0016 0.0368 0.1086
Plasmodium vivax vivapain-2 0.0188 0.6014 1
Brugia malayi Pax transcription factor protein 2 0.0083 0.2573 0.2573
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0188 0.6014 1
Schistosoma mansoni smad1 5 8 and 0.0006 0.004 0.0015
Loa Loa (eye worm) hypothetical protein 0.0012 0.0233 0.0233
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0033 0.0942 0.2906
Entamoeba histolytica cysteine protease, putative 0.0041 0.1206 0.1843
Leishmania major cathepsin L-like protease 0.0188 0.6014 1
Echinococcus multilocularis cathepsin L cysteine protease 0.0188 0.6014 0.6008
Plasmodium falciparum serine repeat antigen 2 0.0041 0.1206 0.1972
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0009 0.0136 0.0136
Loa Loa (eye worm) hypothetical protein 0.0041 0.1206 0.1206
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0041 0.1206 0.1972
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0017 0.0411 0.0411
Loa Loa (eye worm) MH1 domain-containing protein 0.0006 0.004 0.004
Schistosoma mansoni tar DNA-binding protein 0.0022 0.0564 0.054
Echinococcus multilocularis tar DNA binding protein 0.0022 0.0564 0.055
Trypanosoma cruzi cysteine peptidase, putative 0.0188 0.6014 0.6003
Trypanosoma cruzi cysteine peptidase, putative 0.0188 0.6014 0.6003
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0121 0.3821 0.3821
Loa Loa (eye worm) CXXC zinc finger family protein 0.0011 0.0204 0.0204
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0188 0.6014 1
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0059 0.1795 0.1795
Onchocerca volvulus 0.0083 0.2573 0.4279
Giardia lamblia Cathepsin L precursor 0.0041 0.1206 0.2853
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Echinococcus multilocularis lamin dm0 0.0011 0.0195 0.018
Schistosoma mansoni jumonji domain containing protein 0.0023 0.0606 0.0582
Trypanosoma cruzi PAB1-binding protein , putative 0.0009 0.0132 0.0107
Brugia malayi jmjC domain containing protein 0.0024 0.0626 0.0626
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0101 0.3155 0.515
Plasmodium falciparum serine repeat antigen 1 0.0041 0.1206 0.1972
Echinococcus granulosus cathepsin L cysteine proteinase 0.0188 0.6014 0.6008
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0124 0.3926 0.6458
Echinococcus granulosus JmjC domain containing protein 4 0.0006 0.0049 0.0035
Plasmodium vivax unspecified product 0.0101 0.3155 0.5227
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0017 0.0399 0.0473
Onchocerca volvulus 0.0188 0.6014 1
Leishmania major hypothetical protein, conserved 0.0006 0.0049 0.0039
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.3155 0.515
Loa Loa (eye worm) hypothetical protein 0.0188 0.6014 0.6014
Brugia malayi Cell death protein 3 precursor 0.0017 0.0399 0.0399
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0006 0.0049 0.0039
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0006 0.0049 0.0039
Trypanosoma brucei hypothetical protein, conserved 0.0016 0.0368 0.0572
Plasmodium falciparum plasmepsin VI 0.0009 0.0136 0.0184
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0016 0.0368 0.0368
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0005 0.0025 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.1206 0.1843
Echinococcus granulosus geminin 0.0219 0.7048 0.7043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Brugia malayi Importin beta-1 subunit 0.0011 0.0219 0.0219
Giardia lamblia Encystation-specific protease 0.0041 0.1206 0.2853
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0041 0.1206 0.1206
Trypanosoma cruzi cysteine peptidase, putative 0.0059 0.1795 0.1774
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0102 0.3178 1
Echinococcus granulosus cathepsin b 0.0309 1 1
Loa Loa (eye worm) hypothetical protein 0.0006 0.0049 0.0049
Giardia lamblia Cysteine protease 0.0041 0.1206 0.2853
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.1206 0.1843
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0017 0.0399 0.0624
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0005 0.0026 0.0011
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Onchocerca volvulus 0.0188 0.6014 1
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.1206 0.1843
Schistosoma mansoni phosphatidylserine receptor 0.0006 0.0049 0.0024
Loa Loa (eye worm) hypothetical protein 0.0009 0.0132 0.0132
Trichomonas vaginalis D-aminoacylase, putative 0.0016 0.0368 0.042
Echinococcus granulosus cpg binding protein 0.0011 0.0224 0.021
Leishmania major cathepsin L-like protease 0.0188 0.6014 1
Schistosoma mansoni cathepsin D (A01 family) 0.0026 0.0699 0.0676
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0017 0.0399 0.0624
Onchocerca volvulus 0.0008 0.0114 0.019
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Brugia malayi MH2 domain containing protein 0.0006 0.004 0.004
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Mycobacterium leprae conserved hypothetical protein 0.0016 0.0368 0.5
Brugia malayi intermediate filament protein 0.0011 0.0195 0.0195
Onchocerca volvulus 0.0016 0.0368 0.0612
Entamoeba histolytica cysteine protease, putative 0.0041 0.1206 0.1843
Schistosoma mansoni tar DNA-binding protein 0.0022 0.0564 0.054
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0008 0.0121 0.0095
Echinococcus multilocularis cathepsin b 0.0309 1 1
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0129 0.4065 0.405
Trypanosoma cruzi PAB1-binding protein , putative 0.0009 0.0132 0.0107
Schistosoma mansoni cathepsin B (C01 family) 0.0041 0.1206 0.1184
Echinococcus granulosus lamin dm0 0.0011 0.0195 0.018
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0101 0.3155 0.3138
Echinococcus granulosus cysteine protease 0.0101 0.3155 0.3145
Echinococcus multilocularis cathepsin L 0.0101 0.3155 0.3145
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0017 0.0411 0.0411
Leishmania major cysteine peptidase A (CPA) 0.0188 0.6014 1
Trichomonas vaginalis D-aminoacylase, putative 0.0016 0.0368 0.042
Trypanosoma brucei Metacaspase-4 0.0017 0.0399 0.0624
Toxoplasma gondii cathepsin CPC2 0.0041 0.1206 0.1972
Onchocerca volvulus 0.0174 0.5566 0.9255
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0008 0.0114 0.0114
Echinococcus multilocularis Smad4 0.0006 0.004 0.0025
Brugia malayi Papain family cysteine protease containing protein 0.0041 0.1206 0.1206
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0017 0.0399 0.0473
Giardia lamblia Cysteine protease 0.0041 0.1206 0.2853
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.1206 0.1184
Trichomonas vaginalis D-aminoacylase, putative 0.0016 0.0368 0.042
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0124 0.3926 0.6514
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Loa Loa (eye worm) intermediate filament protein 0.0011 0.0195 0.0195
Schistosoma mansoni hypothetical protein 0.0121 0.3821 0.3806
Trypanosoma cruzi cysteine peptidase, putative 0.0101 0.3155 0.3138
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0041 0.1206 0.1184
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0008 0.0121 0.0095
Loa Loa (eye worm) pax transcription factor protein 2 0.0083 0.2573 0.2573
Schistosoma mansoni cathepsin S (C01 family) 0.0041 0.1206 0.1184
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0041 0.1206 0.1972
Echinococcus granulosus caspase 0.0063 0.1914 0.1902
Onchocerca volvulus 0.0188 0.6014 1
Onchocerca volvulus 0.0008 0.0114 0.019
Loa Loa (eye worm) jmjC domain-containing protein 0.0024 0.0626 0.0626
Brugia malayi hypothetical protein 0.0006 0.0031 0.0031
Schistosoma mansoni lozenge 0.0022 0.0564 0.054
Loa Loa (eye worm) RNA binding protein 0.0022 0.0564 0.0564
Brugia malayi jmjC domain containing protein 0.0006 0.0049 0.0049
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0006 0.004 0.0015
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0041 0.1206 0.2853
Brugia malayi cathepsin F-like cysteine proteinase 0.0059 0.1795 0.1795
Loa Loa (eye worm) hypothetical protein 0.0016 0.0368 0.0368
Trypanosoma brucei metacaspase 5, putative 0.0017 0.0399 0.0624
Giardia lamblia Cysteine protease 0.0041 0.1206 0.2853
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0009 0.0136 0.0121
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0041 0.1206 0.1206
Brugia malayi cytoplasmic intermediate filament protein 0.0006 0.0033 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0041 0.1206 0.1843
Trypanosoma cruzi cysteine proteinase, putative 0.0101 0.3155 0.3138
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0041 0.1206 0.1843
Trypanosoma brucei cysteine peptidase C (CPC) 0.0124 0.3926 0.6514
Schistosoma mansoni smad1 5 8 and 0.0006 0.004 0.0015
Onchocerca volvulus 0.0041 0.1206 0.2006
Schistosoma mansoni aldehyde dehydrogenase 0.0033 0.0942 0.0919
Leishmania major metacaspase, putative 0.0017 0.0399 0.0624
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0009 0.0148 0.0047
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0005 0.0026 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0368 0.0343
Mycobacterium tuberculosis Conserved protein 0.0016 0.0368 0.1086
Giardia lamblia Cathepsin L-like protease 0.0041 0.1206 0.2853
Giardia lamblia Cathepsin B precursor 0.0041 0.1206 0.2853
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0309 1 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Plasmodium falciparum plasmepsin II 0.0009 0.0136 0.0184
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.3155 0.515
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0009 0.0136 0.0121
Plasmodium vivax serine-repeat antigen (SERA) 0.0041 0.1206 0.1972
Trypanosoma cruzi metacaspase 5, putative 0.0017 0.0399 0.0375
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0399 0.0473
Onchocerca volvulus 0.0008 0.0114 0.019
Loa Loa (eye worm) ctsf protein 0.0188 0.6014 0.6014
Schistosoma mansoni hypothetical protein 0.0029 0.0784 0.0761
Brugia malayi Cathepsin L-like precursor 0.0188 0.6014 0.6014
Schistosoma mansoni jumonji/arid domain-containing protein 0.0024 0.0626 0.0603
Schistosoma mansoni cpg binding protein 0.0011 0.0204 0.0179
Schistosoma mansoni hypothetical protein 0.0219 0.7048 0.704
Schistosoma mansoni jumonji/arid domain-containing protein 0.0024 0.0626 0.0603
Loa Loa (eye worm) hypothetical protein 0.0059 0.1795 0.1795
Entamoeba histolytica hypothetical protein 0.0009 0.0148 0.0047
Echinococcus multilocularis cathepsin b 0.0309 1 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0008 0.0121 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.1206 0.1843
Schistosoma mansoni lamin 0.0011 0.0195 0.017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Entamoeba histolytica hypothetical protein 0.0029 0.0784 0.1126
Loa Loa (eye worm) hypothetical protein 0.0041 0.1206 0.1206
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0023 0.0606 0.0592
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0017 0.0399 0.0473
Echinococcus granulosus cathepsin b 0.0309 1 1
Echinococcus multilocularis caspase 3 0.0046 0.1361 0.1349
Toxoplasma gondii ABC1 family protein 0.0016 0.0368 0.0572
Schistosoma mansoni smad1 5 8 and 0.0006 0.004 0.0015
Onchocerca volvulus Cathepsin L homolog 0.0188 0.6014 1
Mycobacterium tuberculosis Conserved protein 0.0016 0.0368 0.1086
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0041 0.1206 0.2853
Echinococcus multilocularis JmjC domain containing protein 4 0.0006 0.0049 0.0035
Onchocerca volvulus 0.0188 0.6014 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0011 0.0219 0.0323
Schistosoma mansoni tar DNA-binding protein 0.0022 0.0564 0.054
Trichomonas vaginalis esterase, putative 0.0016 0.0368 0.042
Entamoeba histolytica hypothetical protein 0.0029 0.0784 0.1126
Echinococcus multilocularis cathepsin L cysteine protease 0.0188 0.6014 0.6008
Trypanosoma cruzi cysteine peptidase, putative 0.0188 0.6014 0.6003
Loa Loa (eye worm) hypothetical protein 0.0005 0.0025 0.0025
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0016 0.0368 0.0344
Loa Loa (eye worm) transcription factor SMAD2 0.0086 0.2683 0.2683
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0188 0.6014 1
Schistosoma mansoni smad 0.0006 0.004 0.0015
Echinococcus multilocularis smad 0.0006 0.004 0.0025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0399 0.0473
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0309 1 1
Giardia lamblia Cathepsin L-like protease 0.0041 0.1206 0.2853
Giardia lamblia Cathepsin B precursor 0.0041 0.1206 0.2853
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0041 0.1206 0.1843
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0041 0.1206 0.1206
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0041 0.1206 0.1843
Brugia malayi Papain family cysteine protease containing protein 0.0188 0.6014 0.6014
Mycobacterium ulcerans aldehyde dehydrogenase 0.0033 0.0942 1
Giardia lamblia Cathepsin L precursor 0.0041 0.1206 0.2853
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0011 0.0195 0.0195
Echinococcus granulosus tar DNA binding protein 0.0022 0.0564 0.055
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0188 0.6014 0.6014
Schistosoma mansoni caspase-7 (C14 family) 0.0017 0.0399 0.0375
Loa Loa (eye worm) LBP/BPI/CETP family domain-containing protein 0.0008 0.0114 0.0114
Schistosoma mansoni cathepsin C 0.0041 0.1206 0.1184
Giardia lamblia Cathepsin B precursor 0.0041 0.1206 0.2853
Brugia malayi cathepsin Z-like cysteine proteinase 0.0041 0.1206 0.1206
Echinococcus granulosus cathepsin L 0.0041 0.1206 0.1194
Plasmodium falciparum serine repeat antigen 6 0.0041 0.1206 0.1972
Echinococcus multilocularis cathepsin L 0.0041 0.1206 0.1194
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0041 0.1206 0.1184
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0005 0.0025 0.0011
Schistosoma mansoni transcription factor LCR-F1 0.0029 0.0784 0.0761
Brugia malayi jmjC domain containing protein 0.0023 0.0606 0.0606
Echinococcus granulosus cathepsin L cysteine protease 0.0101 0.3155 0.3145
Toxoplasma gondii LsmAD domain-containing protein 0.0009 0.0132 0.0178
Echinococcus granulosus cathepsin l1 0.0188 0.6014 0.6008
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0188 0.6014 1
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0016 0.0368 0.1086
Trichomonas vaginalis penicillin-binding protein, putative 0.0016 0.0368 0.042
Leishmania major cathepsin L-like protease 0.0188 0.6014 1
Echinococcus granulosus jumonji domain containing 1A 0.0006 0.0049 0.0035
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0041 0.1206 0.1972
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Loa Loa (eye worm) hypothetical protein 0.0174 0.5566 0.5566
Trypanosoma cruzi cysteine protease, putative 0.0101 0.3155 0.3138
Loa Loa (eye worm) hypothetical protein 0.0017 0.0411 0.0411
Brugia malayi jmjC domain containing protein 0.0006 0.0049 0.0049
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0101 0.3155 0.3138
Echinococcus multilocularis jumonji domain containing 1A 0.0006 0.0049 0.0035
Loa Loa (eye worm) hypothetical protein 0.0005 0.0008 0.0008
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0041 0.1206 0.1843
Loa Loa (eye worm) MH2 domain-containing protein 0.0006 0.004 0.004
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0009 0.0148 0.0047
Entamoeba histolytica cysteine protease, putative 0.0188 0.6014 1
Echinococcus multilocularis lysine specific demethylase 6a 0.0006 0.0049 0.0035
Plasmodium vivax ataxin-2 like protein, putative 0.0009 0.0132 0.0178
Loa Loa (eye worm) cathepsin B 0.0124 0.3926 0.3926
Schistosoma mansoni intermediate filament proteins 0.0011 0.0195 0.017
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.1206 0.1184
Loa Loa (eye worm) hypothetical protein 0.0016 0.0368 0.0368
Entamoeba histolytica cysteine protease, putative 0.0041 0.1206 0.1843
Loa Loa (eye worm) fibroinase 0.0188 0.6014 0.6014
Schistosoma mansoni caspase-7 (C14 family) 0.0063 0.1914 0.1893
Brugia malayi Papain family cysteine protease containing protein 0.0041 0.1206 0.1206
Onchocerca volvulus 0.0188 0.6014 1
Plasmodium vivax unspecified product 0.0059 0.1795 0.2956
Trypanosoma brucei metacaspase 0.0017 0.0399 0.0624
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Brugia malayi hypothetical protein 0.0029 0.0784 0.0784
Entamoeba histolytica cysteine proteinase, putative 0.0188 0.6014 1
Loa Loa (eye worm) hypothetical protein 0.0059 0.1795 0.1795
Plasmodium vivax JmjC domain containing protein 0.0006 0.0049 0.0039
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0005 0.0025 0.0011
Onchocerca volvulus Cathepsin L homolog 0.0041 0.1206 0.2006
Schistosoma mansoni cpg binding protein 0.0011 0.0224 0.0199
Echinococcus multilocularis caspase 0.0063 0.1914 0.1902
Schistosoma mansoni cathepsin s 0.0059 0.1795 0.1775
Loa Loa (eye worm) hypothetical protein 0.0041 0.1206 0.1206
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Giardia lamblia Cathepsin B precursor 0.0124 0.3926 1
Brugia malayi Cathepsin L-like precursor 0.0129 0.4065 0.4065
Brugia malayi RNA recognition motif domain containing protein 0.0022 0.0564 0.0564
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0033 0.0942 0.153
Brugia malayi cathepsin Z-like cysteine proteinase 0.0041 0.1206 0.1206
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0399 0.0473
Schistosoma mansoni cathepsin F (C01 family) 0.0188 0.6014 0.6003
Brugia malayi Cathepsin L-like precursor 0.0188 0.6014 0.6014
Brugia malayi CXXC zinc finger family protein 0.0011 0.0204 0.0204
Onchocerca volvulus 0.0008 0.0114 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0041 0.1206 0.1843
Plasmodium falciparum importin beta, putative 0.0011 0.0219 0.0323
Trypanosoma cruzi metacaspase, putative 0.0017 0.0399 0.0375
Leishmania major cathepsin L-like protease 0.0188 0.6014 1
Schistosoma mansoni aldehyde dehydrogenase 0.0033 0.0942 0.0919
Brugia malayi Calcitonin receptor-like protein seb-1 0.0017 0.0411 0.0411
Echinococcus granulosus mothers against decapentaplegic 5 0.0006 0.004 0.0025
Onchocerca volvulus 0.0016 0.0368 0.0612
Plasmodium vivax importin-beta 2, putative 0.0011 0.0219 0.0323
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0063 0.1914 0.1902
Loa Loa (eye worm) hypothetical protein 0.0309 1 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0008 0.0008
Brugia malayi TAR-binding protein 0.0022 0.0564 0.0564
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0006 0.0049 0.0024
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Entamoeba histolytica hypothetical protein 0.0029 0.0784 0.1126
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0033 0.0942 0.0928
Trypanosoma cruzi cruzipain precursor, putative 0.0059 0.1795 0.1774
Giardia lamblia Cathepsin B precursor 0.0124 0.3926 1
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0007 0.0069 0.0055
Brugia malayi latrophilin 2 splice variant baaae 0.0012 0.0233 0.0233
Toxoplasma gondii cathepsin B 0.0124 0.3926 0.6514
Echinococcus granulosus caspase 2 0.0017 0.0399 0.0385
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Echinococcus multilocularis caspase 2 0.0017 0.0399 0.0385
Brugia malayi LBP / BPI / CETP family, C-terminal domain containing protein 0.0008 0.0114 0.0114
Echinococcus multilocularis GPCR, family 2 0.0005 0.0025 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0129 0.4065 0.6693
Echinococcus granulosus caspase 3 0.0046 0.1361 0.1349
Brugia malayi Cathepsin L-like precursor 0.0188 0.6014 0.6014
Onchocerca volvulus 0.0011 0.0204 0.0338
Loa Loa (eye worm) hypothetical protein 0.0016 0.0368 0.0368
Toxoplasma gondii aldehyde dehydrogenase 0.0033 0.0942 0.153
Leishmania major GTP-binding protein, putative 0.0008 0.0121 0.0159
Trypanosoma cruzi major cysteine proteinase, putative 0.0041 0.1206 0.1184
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0188 0.6014 1
Onchocerca volvulus 0.0008 0.0114 0.019
Entamoeba histolytica cysteine proteinase, putative 0.0101 0.3155 0.515
Plasmodium falciparum serine repeat antigen 8 0.0041 0.1206 0.1972
Trypanosoma cruzi hypothetical protein, conserved 0.0016 0.0368 0.0343
Echinococcus granulosus caspase 8 0.0017 0.0399 0.0385
Plasmodium falciparum metacaspase-like protein 0.0017 0.0399 0.0624
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0399 0.0473
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0041 0.1206 0.1184
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0041 0.1206 0.1972
Trypanosoma cruzi cysteine proteinase, putative 0.0101 0.3155 0.3138
Plasmodium falciparum JmjC domain-containing protein, putative 0.0006 0.0049 0.0039
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0188 0.6014 0.6008
Onchocerca volvulus 0.0008 0.0114 0.019
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0368 0.0572
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0017 0.0399 0.0473
Entamoeba histolytica cysteine proteinase 1, putative 0.0101 0.3155 0.515
Brugia malayi Cathepsin L-like precursor 0.0188 0.6014 0.6014
Echinococcus multilocularis isocitrate dehydrogenase 0.0005 0.0026 0.0011
Plasmodium falciparum serine repeat antigen 3 0.0041 0.1206 0.1972
Brugia malayi Cathepsin L-like precursor 0.0188 0.6014 0.6014
Giardia lamblia Cathepsin L precursor 0.0041 0.1206 0.2853
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0016 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0017 0.0399 0.0399
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0005 0.0026 0.0011
Onchocerca volvulus Cathepsin L homolog 0.0188 0.6014 1
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0041 0.1206 0.1972
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0309 1 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0368 0.0368
Echinococcus granulosus Smad4 0.0006 0.004 0.0025
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0041 0.1206 0.1843
Leishmania major hypothetical protein, conserved 0.0009 0.0132 0.0178
Echinococcus granulosus cathepsin l1 0.0129 0.4065 0.4056
Schistosoma mansoni ran 0.0008 0.0121 0.0096
Plasmodium falciparum serine repeat antigen 9 0.0041 0.1206 0.1972
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0006 0.0049 0.0024
Echinococcus multilocularis beta LACTamase domain containing family member 0.0016 0.0368 0.0354
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0041 0.1206 0.2853
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0009 0.0136 0.0184
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0188 0.6014 0.6008
Echinococcus granulosus GTP binding nuclear protein Ran 0.0008 0.0121 0.0106
Plasmodium vivax vivapain-3 0.0101 0.3155 0.5227
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0188 0.6014 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Echinococcus granulosus lamin 0.0011 0.0195 0.018
Schistosoma mansoni caspase-3 (C14 family) 0.0063 0.1914 0.1893
Schistosoma mansoni hypothetical protein 0.0219 0.7048 0.704
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0005 0.0025 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0041 0.1206 0.1843
Schistosoma mansoni Smad4 0.0006 0.004 0.0015
Schistosoma mansoni tar DNA-binding protein 0.0022 0.0564 0.054
Loa Loa (eye worm) runx1 0.0022 0.0564 0.0564
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0008 0.0121 0.0106
Echinococcus granulosus importin subunit beta 1 0.0011 0.0219 0.0205
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0188 0.6014 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0033 0.0942 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0129 0.4065 0.6693
Plasmodium falciparum ataxin-2 like protein, putative 0.0009 0.0132 0.0178
Trypanosoma cruzi cruzipain precursor, putative 0.0188 0.6014 0.6003
Leishmania major cathepsin L-like protease 0.0188 0.6014 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0101 0.3155 0.3138
Echinococcus multilocularis musashi 0.0011 0.0195 0.018
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0006 0.0049 0.0024
Mycobacterium leprae Probable lipase LipE 0.0016 0.0368 0.5
Brugia malayi cathepsin F-like cysteine proteinase 0.0041 0.1206 0.1206
Echinococcus multilocularis importin subunit beta 1 0.0011 0.0219 0.0205
Plasmodium falciparum plasmepsin I 0.0009 0.0136 0.0184
Echinococcus granulosus cathepsin L 0.0101 0.3155 0.3145
Onchocerca volvulus Cell death protein 3 homolog 0.0017 0.0399 0.0664
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0017 0.0399 0.0399
Plasmodium vivax metacaspase 1, putative 0.0017 0.0399 0.0624
Onchocerca volvulus Cathepsin F homolog 0.0188 0.6014 1
Giardia lamblia Cathepsin L precursor 0.0041 0.1206 0.2853
Brugia malayi beta-lactamase family protein 0.0016 0.0368 0.0368
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0041 0.1206 0.2853
Plasmodium falciparum metacaspase 1 0.0017 0.0399 0.0624
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.3155 0.5227
Loa Loa (eye worm) TAR-binding protein 0.0022 0.0564 0.0564
Brugia malayi RNA, U transporter 1 0.0032 0.0905 0.0905
Brugia malayi Papain family cysteine protease containing protein 0.0041 0.1206 0.1206
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0059 0.1795 0.1795
Echinococcus multilocularis mothers against decapentaplegic 5 0.0006 0.004 0.0025
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0188 0.6014 1
Plasmodium vivax vivapain-1 0.0101 0.3155 0.5227
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0041 0.1206 0.1206
Toxoplasma gondii histone lysine methyltransferase SET1 0.0021 0.0523 0.0831
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0006 0.004 0.0025
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0041 0.1206 0.1972
Echinococcus multilocularis lysine specific demethylase 5A 0.0023 0.0606 0.0592
Plasmodium falciparum plasmepsin IV 0.0009 0.0136 0.0184
Brugia malayi hypothetical protein 0.0174 0.5566 0.5566
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0101 0.3155 0.5227
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.1206 0.1843
Loa Loa (eye worm) hypothetical protein 0.0011 0.0219 0.0219
Entamoeba histolytica cysteine proteinase, putative 0.0129 0.4065 0.6693
Plasmodium vivax serine-repeat antigen (SERA) 0.0041 0.1206 0.1972
Trypanosoma cruzi metacaspase 5, putative 0.0017 0.0399 0.0375
Echinococcus granulosus snurportin 1 0.0121 0.3821 0.3812
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0009 0.0136 0.0111
Schistosoma mansoni protein phosphatase 2C 0.0006 0.0049 0.0024
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Onchocerca volvulus 0.0016 0.0368 0.0612
Entamoeba histolytica cysteine protease, putative 0.0041 0.1206 0.1843
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0041 0.1206 0.1843
Schistosoma mansoni importin beta-1 0.0011 0.0219 0.0194
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0399 0.0473
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0006 0.0049 0.0039
Loa Loa (eye worm) hypothetical protein 0.0129 0.4065 0.4065
Toxoplasma gondii cathepsin CPC1 0.0041 0.1206 0.1972
Trypanosoma brucei PAB1-binding protein , putative 0.0009 0.0132 0.0178
Echinococcus multilocularis cpg binding protein 0.0011 0.0224 0.021
Echinococcus multilocularis caspase 8 0.0017 0.0399 0.0385
Trypanosoma brucei metacaspase MCA3 0.0017 0.0399 0.0624
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Plasmodium falciparum serine repeat antigen 7 0.0041 0.1206 0.1972
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0009 0.0136 0.0026
Leishmania major importin beta-1 subunit, putative 0.0009 0.0148 0.0205
Schistosoma mansoni cathepsin F (C01 family) 0.0129 0.4065 0.405
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0604 0.058
Plasmodium vivax hypothetical protein, conserved 0.0017 0.0399 0.0624
Leishmania major cathepsin L-like protease 0.0188 0.6014 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0033 0.0942 1
Loa Loa (eye worm) hypothetical protein 0.0005 0.0015 0.0015
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0188 0.6014 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0006 0.0049 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.1206 0.1843
Plasmodium vivax aspartyl proteinase, putative 0.0009 0.0136 0.0184
Brugia malayi MH2 domain containing protein 0.0006 0.004 0.004
Loa Loa (eye worm) Smad1 0.0006 0.004 0.004
Brugia malayi fibroinase precursor 0.0041 0.1206 0.1206
Loa Loa (eye worm) cysteine protease 0.0188 0.6014 0.6014
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0008 0.0121 0.0159
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.1206 0.1184
Loa Loa (eye worm) hypothetical protein 0.0041 0.1206 0.1206
Leishmania major hypothetical protein, conserved 0.0016 0.0368 0.0572
Brugia malayi hypothetical protein 0.0009 0.0132 0.0132
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0005 0.0026 0.0011
Loa Loa (eye worm) hypothetical protein 0.0016 0.0368 0.0368
Echinococcus granulosus beta LACTamase domain containing family member 0.0016 0.0368 0.0354
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0101 0.3155 0.3138
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0017 0.0399 0.0375
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0022 0.0564 0.0564
Brugia malayi Isocitrate dehydrogenase 0.0005 0.0026 0.0026
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0041 0.1206 0.1843
Toxoplasma gondii aspartyl protease ASP1 0.0009 0.0136 0.0184
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0017 0.0399 0.0473
Echinococcus granulosus lysine specific demethylase 5A 0.0024 0.0626 0.0613
Loa Loa (eye worm) hypothetical protein 0.0006 0.0049 0.0049
Echinococcus granulosus smad 0.0006 0.004 0.0025
Loa Loa (eye worm) hypothetical protein 0.0006 0.0049 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0041 0.1206 0.1843
Plasmodium falciparum cysteine proteinase falcipain 1 0.0101 0.3155 0.5227
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.1206 0.1843
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Loa Loa (eye worm) hypothetical protein 0.0129 0.4065 0.4065
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0008 0.0121 0.0159
Giardia lamblia Cathepsin L precursor 0.0041 0.1206 0.2853
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0041 0.1206 0.1972
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0041 0.1206 0.1972
Echinococcus granulosus cathepsin l cysteine peptidase 0.0188 0.6014 0.6008
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0041 0.1206 0.1972
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0005 0.0026 0.0011
Plasmodium falciparum serine repeat antigen 4 0.0041 0.1206 0.1972
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Giardia lamblia Cathepsin B precursor 0.0041 0.1206 0.2853
Toxoplasma gondii preprocathepsin c precursor, putative 0.0041 0.1206 0.1972
Echinococcus granulosus GPCR family 2 0.0005 0.0025 0.0011
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0008 0.0121 0.0121
Brugia malayi MH1 domain containing protein 0.0006 0.004 0.004
Schistosoma mansoni jumonji domain containing protein 0.0006 0.0049 0.0024
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0041 0.1206 0.1843
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0041 0.1206 0.1184
Brugia malayi LBP / BPI / CETP family, N-terminal domain containing protein 0.0008 0.0114 0.0114
Trypanosoma cruzi cysteine peptidase, putative 0.0188 0.6014 0.6003
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0041 0.1206 0.1184
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0006 0.0033 0.0033
Schistosoma mansoni ran 0.0008 0.0121 0.0096
Giardia lamblia Cathepsin L precursor 0.0041 0.1206 0.2853
Trypanosoma cruzi importin beta-1 subunit, putative 0.0009 0.0148 0.0123
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0188 0.6014 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0188 0.6014 1
Entamoeba histolytica cysteine protease, putative 0.0101 0.3155 0.515
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0041 0.1206 0.1972
Echinococcus granulosus lysine specific demethylase 6a 0.0006 0.0049 0.0035
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0041 0.1206 0.1972
Schistosoma mansoni cpg binding protein 0.0011 0.0224 0.0199
Brugia malayi jmjC domain containing protein 0.0006 0.0049 0.0049
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0029 0.0784 0.0771
Toxoplasma gondii cathepsin CPL 0.0188 0.6014 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0041 0.1206 0.1184
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0188 0.6014 1
Brugia malayi beta-lactamase family protein 0.0016 0.0368 0.0368
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0309 1 1
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0188 0.6014 1
Entamoeba histolytica hypothetical protein 0.0041 0.1206 0.1843
Schistosoma mansoni tar DNA-binding protein 0.0022 0.0564 0.054
Onchocerca volvulus 0.0011 0.0195 0.0324
Plasmodium vivax vivapain-2 0.0188 0.6014 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0008 0.0121 0.0159
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0041 0.1206 0.1972
Loa Loa (eye worm) hypothetical protein 0.0017 0.0399 0.0399

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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