Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | 6-phosphogluconolactonase, putative | 0.013 | 1 | 0.5 |
Trypanosoma cruzi | 6-phosphogluconolactonase, putative | 0.013 | 1 | 0.5 |
Treponema pallidum | glucose-6-phosphate 1-dehydrogenase | 0.013 | 1 | 0.5 |
Chlamydia trachomatis | 6-phosphogluconolactonase | 0.013 | 1 | 0.5 |
Loa Loa (eye worm) | 6-phosphogluconolactonase | 0.013 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable 6-phosphogluconolactonase DevB (6PGL) | 0.0092 | 0 | 0.5 |
Mycobacterium ulcerans | 6-phosphogluconolactonase | 0.013 | 1 | 0.5 |
Echinococcus multilocularis | 6 phosphogluconolactonase | 0.013 | 1 | 0.5 |
Leishmania major | 6-phosphogluconolactonase | 0.013 | 1 | 0.5 |
Trypanosoma brucei | 6-phosphogluconolactonase | 0.013 | 1 | 0.5 |
Schistosoma mansoni | 6-phosphogluconolactonase | 0.013 | 1 | 0.5 |
Mycobacterium leprae | Probable 6-phosphogluconolactonase DevB (6PGL) | 0.013 | 1 | 0.5 |
Echinococcus granulosus | 6 phosphogluconolactonase | 0.013 | 1 | 0.5 |
Schistosoma mansoni | 6-phosphogluconolactonase | 0.013 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.