Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | 6 phosphogluconolactonase | 0.013 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable 6-phosphogluconolactonase DevB (6PGL) | 0.0092 | 0.5903 | 0.5 |
Giardia lamblia | Glucosamine-6-phosphate deaminase | 0.0038 | 0 | 0.5 |
Mycobacterium leprae | Probable 6-phosphogluconolactonase DevB (6PGL) | 0.013 | 1 | 0.5 |
Trichomonas vaginalis | glucosamine-6-phosphate isomerase, putative | 0.0038 | 0 | 0.5 |
Echinococcus multilocularis | 6 phosphogluconolactonase | 0.013 | 1 | 0.5 |
Loa Loa (eye worm) | 6-phosphogluconolactonase | 0.013 | 1 | 0.5 |
Trichomonas vaginalis | glucosamine-6-phosphate isomerase, putative | 0.0038 | 0 | 0.5 |
Trypanosoma cruzi | 6-phosphogluconolactonase, putative | 0.013 | 1 | 1 |
Toxoplasma gondii | glucose-6-phosphate 1-dehydrogenase | 0.0038 | 0 | 0.5 |
Trypanosoma cruzi | 6-phosphogluconolactonase, putative | 0.013 | 1 | 1 |
Trichomonas vaginalis | glucosamine-6-phosphate isomerase, putative | 0.0038 | 0 | 0.5 |
Trypanosoma brucei | 6-phosphogluconolactonase | 0.013 | 1 | 1 |
Chlamydia trachomatis | 6-phosphogluconolactonase | 0.013 | 1 | 0.5 |
Treponema pallidum | glucose-6-phosphate 1-dehydrogenase | 0.013 | 1 | 0.5 |
Giardia lamblia | Glucose-6-phosphate 1-dehydrogenase | 0.0038 | 0 | 0.5 |
Plasmodium vivax | glucose-6-phosphate 1-dehydrogenase, putative | 0.0038 | 0 | 0.5 |
Mycobacterium ulcerans | 6-phosphogluconolactonase | 0.013 | 1 | 0.5 |
Leishmania major | 6-phosphogluconolactonase | 0.013 | 1 | 1 |
Giardia lamblia | Glucosamine-6-phosphate deaminase | 0.0038 | 0 | 0.5 |
Entamoeba histolytica | glucosamine-6-phosphate isomerase, putative | 0.0038 | 0 | 0.5 |
Trichomonas vaginalis | 6-phosphogluconolactonase, putative | 0.0038 | 0 | 0.5 |
Plasmodium falciparum | glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | 0.0038 | 0 | 0.5 |
Schistosoma mansoni | 6-phosphogluconolactonase | 0.013 | 1 | 1 |
Schistosoma mansoni | 6-phosphogluconolactonase | 0.013 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.