Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | beta-N-acetylhexosaminidase, putative | 0.0216 | 0.0865 | 0.5 |
Trichomonas vaginalis | beta-hexosaminidase B, putative | 0.0135 | 0.027 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0622 | 0.3835 | 0.3835 |
Schistosoma mansoni | aminopeptidase P homologue (M24 family) | 0.1463 | 1 | 1 |
Brugia malayi | Glycosyl hydrolase family 20, catalytic domain containing protein | 0.0216 | 0.0865 | 0.0865 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0135 | 0.027 | 0.5 |
Trypanosoma cruzi | endo-beta-N-acetylglucosaminidase, putative | 0.0098 | 0 | 0.5 |
Echinococcus multilocularis | bifunctional protein NCOAT | 0.1463 | 1 | 1 |
Echinococcus granulosus | bifunctional protein NCOAT | 0.1463 | 1 | 1 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, beta subunit | 0.0216 | 0.0865 | 0.5 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0135 | 0.027 | 0.5 |
Trypanosoma cruzi | endo-beta-N-acetylglucosaminidase, putative | 0.0098 | 0 | 0.5 |
Trypanosoma brucei | endo-beta-N-acetylglucosaminidase, putative | 0.0098 | 0 | 0.5 |
Leishmania major | glycosyl hydrolase-like protein | 0.0098 | 0 | 0.5 |
Echinococcus granulosus | beta hexosaminidase subunit beta | 0.0216 | 0.0865 | 0.0865 |
Echinococcus multilocularis | beta hexosaminidase subunit beta | 0.0216 | 0.0865 | 0.0865 |
Schistosoma mansoni | Hyaluronidase | 0.1463 | 1 | 1 |
Schistosoma mansoni | beta-hexosaminidase B | 0.0216 | 0.0865 | 0.0865 |
Loa Loa (eye worm) | hyaluronidase | 0.1463 | 1 | 1 |
Echinococcus multilocularis | beta hexosaminidase subunit alpha | 0.0135 | 0.027 | 0.027 |
Schistosoma mansoni | beta-hexosaminidase B | 0.0216 | 0.0865 | 0.0865 |
Loa Loa (eye worm) | glycosyl hydrolase family 20 | 0.0216 | 0.0865 | 0.0865 |
Echinococcus granulosus | beta hexosaminidase subunit alpha | 0.0135 | 0.027 | 0.027 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, putative | 0.0216 | 0.0865 | 0.5 |
Entamoeba histolytica | beta-N-acetylhexosaminidase, alpha subunit | 0.0216 | 0.0865 | 0.5 |
Trichomonas vaginalis | beta-hexosaminidase, putative | 0.0135 | 0.027 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.