Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | mannosidase | 0.0454 | 0.4169 | 0.397 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0067 | 0.0376 | 0.0119 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1048 | 1 | 1 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.0432 | 0.0105 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Trypanosoma brucei | endo-beta-N-acetylglucosaminidase, putative | 0.0087 | 0.0571 | 0.1493 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0454 | 0.4169 | 0.3996 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0688 | 0.6464 | 0.6359 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1048 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha mannosidase | 0.0227 | 0.1945 | 0.4487 |
Echinococcus granulosus | er degradation enhancer mannosidase alpha | 0.0063 | 0.033 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0454 | 0.4169 | 0.397 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0403 | 0.0075 |
Brugia malayi | Alpha-mannosidase C1orf22 | 0.0063 | 0.033 | 0.0198 |
Trypanosoma cruzi | lysosomal alpha-mannosidase precursor, putative | 0.0227 | 0.1945 | 1 |
Trichomonas vaginalis | alpha-mannosidase, putative | 0.0194 | 0.1619 | 0.1371 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Echinococcus granulosus | endoplasmic reticulum mannosyl oligosaccharide | 0.0454 | 0.4169 | 1 |
Trypanosoma cruzi | endo-beta-N-acetylglucosaminidase, putative | 0.0087 | 0.0571 | 0.1493 |
Loa Loa (eye worm) | hypothetical protein | 0.0145 | 0.1141 | 0.0839 |
Echinococcus granulosus | endo beta n-acetylglucosaminidase | 0.0087 | 0.0571 | 0.1081 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.033 | 0.0044 |
Trypanosoma cruzi | endo-beta-N-acetylglucosaminidase, putative | 0.0087 | 0.0571 | 0.1493 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Schistosoma mansoni | sphingoid long chain base kinase | 0.0073 | 0.0432 | 0.0265 |
Trichomonas vaginalis | glycoside hydrolases, putative | 0.0132 | 0.101 | 0.0744 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0688 | 0.6464 | 0.6359 |
Loa Loa (eye worm) | hypothetical protein | 0.0454 | 0.4169 | 0.397 |
Schistosoma mansoni | lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) | 0.0227 | 0.1945 | 0.4207 |
Brugia malayi | Alpha-mannosidase C1orf22 | 0.0063 | 0.033 | 0.0198 |
Brugia malayi | Glycosyl hydrolases family 38 protein | 0.0194 | 0.1619 | 0.1504 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1048 | 1 | 1 |
Echinococcus multilocularis | mannosyl oligosaccharide 1,2 alpha mannosidase | 0.0454 | 0.4169 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.033 | 0.0044 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0073 | 0.0432 | 0.5 |
Echinococcus granulosus | Alpha N acetylgalactosaminidase | 0.0101 | 0.0705 | 0.1413 |
Echinococcus multilocularis | er degradation enhancing alpha mannosidase | 0.0063 | 0.033 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0376 | 0.0047 |
Echinococcus multilocularis | Glycoside hydrolase, family 27 | 0.0101 | 0.0705 | 0.1413 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Echinococcus granulosus | mannosyl oligosaccharide 12 alpha mannosidase | 0.0454 | 0.4169 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0101 | 0.0705 | 0.0977 |
Brugia malayi | Glycosyl hydrolases family 38 protein | 0.0269 | 0.2358 | 0.2253 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0688 | 0.6464 | 0.6359 |
Trichomonas vaginalis | beta-glucosidase, putative | 0.0132 | 0.101 | 0.0744 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1048 | 1 | 1 |
Echinococcus granulosus | er degradation enhancing alpha mannosidase | 0.0063 | 0.033 | 0.0483 |
Schistosoma mansoni | lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) | 0.0124 | 0.0932 | 0.1569 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0101 | 0.0705 | 0.0977 |
Echinococcus granulosus | alpha mannosidase 2 | 0.0145 | 0.1141 | 0.2495 |
Loa Loa (eye worm) | glycosyl hydrolase family 38 protein | 0.0194 | 0.1619 | 0.1333 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0688 | 0.6464 | 0.6359 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.0403 | 0.0075 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0101 | 0.0705 | 0.0977 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0063 | 0.033 | 0.0044 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0101 | 0.0705 | 0.0977 |
Schistosoma mansoni | sphingosine kinase A B | 0.0073 | 0.0432 | 0.0265 |
Trypanosoma brucei | lysosomal alpha-mannosidase precursor, putative | 0.0227 | 0.1945 | 1 |
Brugia malayi | Alpha-mannosidase C1orf22 | 0.0063 | 0.033 | 0.0198 |
Brugia malayi | Melibiase family protein | 0.0067 | 0.0376 | 0.0244 |
Leishmania major | glycosyl hydrolase-like protein | 0.0087 | 0.0571 | 0.5 |
Schistosoma mansoni | mannosyl-oligosaccharide alpha-12-mannosidase | 0.0454 | 0.4169 | 1 |
Echinococcus multilocularis | transfer RNA-Trp | 0.0454 | 0.4169 | 1 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0063 | 0.033 | 0.0044 |
Trichomonas vaginalis | conserved hypothetical protein | 0.007 | 0.0403 | 0.0119 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0725 | 0.6827 | 0.6733 |
Trypanosoma brucei | lysosomal alpha-mannosidase precursor, putative | 0.0169 | 0.1373 | 0.6461 |
Brugia malayi | Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform 1 | 0.0454 | 0.4169 | 0.4089 |
Brugia malayi | Glycosyl hydrolase family 47 protein | 0.0063 | 0.033 | 0.0198 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0688 | 0.6464 | 0.6359 |
Echinococcus granulosus | alpha mannosidase 2 | 0.0134 | 0.1026 | 0.2209 |
Brugia malayi | lysosomal alpha-mannosidase | 0.0194 | 0.1619 | 0.1504 |
Echinococcus multilocularis | alpha mannosidase 2 | 0.0269 | 0.2358 | 0.551 |
Echinococcus multilocularis | er degradation enhancing alpha mannosidase er degradation enhancer mannosidase alpha | 0.0063 | 0.033 | 0.0483 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0688 | 0.6464 | 0.6359 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.033 | 0.0044 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0725 | 0.6827 | 0.6733 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0063 | 0.033 | 0.0044 |
Schistosoma mansoni | endo beta n-acetylglucosaminidase | 0.0087 | 0.0571 | 0.0628 |
Echinococcus multilocularis | Alpha N acetylgalactosaminidase | 0.0101 | 0.0705 | 0.1413 |
Trichomonas vaginalis | Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA, putative | 0.0063 | 0.033 | 0.0044 |
Echinococcus multilocularis | er degradation enhancing alpha mannosidase er degradation enhancer mannosidase alpha | 0.0063 | 0.033 | 0.0483 |
Echinococcus multilocularis | sphingosine kinase 1 | 0.0073 | 0.0432 | 0.0736 |
Trichomonas vaginalis | alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative | 0.0067 | 0.0376 | 0.0091 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.0932 | 0.0623 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0063 | 0.033 | 0.0044 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0688 | 0.6464 | 0.6359 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.033 | 0.0044 |
Echinococcus granulosus | lysosomal alpha mannosidase | 0.0227 | 0.1945 | 0.4487 |
Trichomonas vaginalis | Mannosyl-oligosaccharide alpha-1,2-mannosidase isoform, putative | 0.0063 | 0.033 | 0.0044 |
Brugia malayi | Alpha-mannosidase C1orf22 | 0.0063 | 0.033 | 0.0198 |
Trichomonas vaginalis | alpha-mannosidase 2c1, putative | 0.0194 | 0.1619 | 0.1371 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.033 | 0.0044 |
Echinococcus granulosus | er degradation enhancing alpha mannosidase | 0.0063 | 0.033 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.1258 | 0.096 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.033 | 0.0044 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Echinococcus granulosus | sphingosine kinase 1 | 0.0073 | 0.0432 | 0.0736 |
Brugia malayi | Glycosyl hydrolases family 38 protein | 0.0194 | 0.1619 | 0.1504 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.1048 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1048 | 1 | 1 |
Trichomonas vaginalis | alpha-mannosidase 2c1, putative | 0.007 | 0.0403 | 0.0119 |
Loa Loa (eye worm) | hypothetical protein | 0.0269 | 0.2358 | 0.2097 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0063 | 0.033 | 0.0044 |
Trypanosoma cruzi | lysosomal alpha-mannosidase precursor, putative | 0.0227 | 0.1945 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.1048 | 1 | 1 |
Schistosoma mansoni | alpha-galactosidase/alpha-n-acetylgalactosaminidase | 0.0067 | 0.0376 | 0.0119 |
Echinococcus multilocularis | endo beta n-acetylglucosaminidase | 0.0087 | 0.0571 | 0.1081 |
Loa Loa (eye worm) | hypothetical protein | 0.0194 | 0.1619 | 0.1333 |
Mycobacterium tuberculosis | Conserved protein | 0.0073 | 0.0432 | 0.5 |
Echinococcus multilocularis | endoplasmic reticulum mannosyl oligosaccharide | 0.0454 | 0.4169 | 1 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Brugia malayi | Glycosyl hydrolase family 85 protein | 0.0087 | 0.0571 | 0.0442 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0688 | 0.6464 | 1 |
Toxoplasma gondii | melibiase subfamily protein | 0.0101 | 0.0705 | 1 |
Loa Loa (eye worm) | glycosyl hydrolase family 85 protein | 0.0087 | 0.0571 | 0.0249 |
Schistosoma mansoni | mannosidase alpha class 2a | 0.0269 | 0.2358 | 0.5282 |
Echinococcus multilocularis | ER degradation enhancer, mannosidase alpha | 0.0063 | 0.033 | 0.0483 |
Loa Loa (eye worm) | hypothetical protein | 0.0391 | 0.3555 | 0.3335 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0063 | 0.033 | 0.0044 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Trichomonas vaginalis | endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase, putative | 0.0454 | 0.4169 | 0.3996 |
Mycobacterium ulcerans | alpha-mannosidase | 0.0194 | 0.1619 | 1 |
Trichomonas vaginalis | mannosyl-oligosaccharide alpha-1,2-mannosidase, putative | 0.0063 | 0.033 | 0.0044 |
Echinococcus granulosus | er degradation enhancing alpha mannosidase | 0.0063 | 0.033 | 0.0483 |
Schistosoma mansoni | lysosomal alpha-mannosidase (mannosidase alpha class 2b member 1) | 0.0194 | 0.1619 | 0.3357 |
Brugia malayi | ER degradation-enhancing alpha-mannosidase-like, putative | 0.0063 | 0.033 | 0.0198 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.