Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0491 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0491 | 1 | 1 |
Treponema pallidum | adenosine deaminase | 0.0491 | 1 | 0.5 |
Plasmodium vivax | adenosine deaminase, putative | 0.0491 | 1 | 0.5 |
Echinococcus granulosus | adenosine deaminase | 0.0491 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0491 | 1 | 0.5 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0491 | 1 | 0.5 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0491 | 1 | 0.5 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0491 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0491 | 1 | 0.5 |
Mycobacterium ulcerans | adenosine deaminase | 0.0491 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0491 | 1 | 0.5 |
Echinococcus multilocularis | adenosine deaminase | 0.0491 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase | 0.0491 | 1 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0491 | 1 | 0.5 |
Plasmodium falciparum | adenosine deaminase | 0.0491 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0491 | 1 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0491 | 1 | 0.5 |
Leishmania major | adenine aminohydrolase | 0.0491 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.