Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.053 | 0.1687 | 0.167 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0514 | 0.1546 | 0.4309 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0743 | 0.3561 | 0.3548 |
Brugia malayi | Ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Schistosoma mansoni | alpha-glucosidase | 0.1291 | 0.8384 | 1 |
Leishmania major | alpha glucosidase II subunit, putative | 0.034 | 0.002 | 0.5 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0338 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.034 | 0.002 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.4257 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.034 | 0.002 | 0.5 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0785 | 0.3929 | 0.4674 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0785 | 0.3929 | 0.4674 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0743 | 0.3561 | 0.3548 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.0785 | 0.3929 | 0.3917 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1475 | 1 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1475 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.034 | 0.002 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.1291 | 0.8384 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0514 | 0.1546 | 0.4309 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.4257 |
Echinococcus granulosus | bile acid beta glucosidase | 0.0785 | 0.3929 | 0.3917 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Onchocerca volvulus | 0.0919 | 0.5106 | 1 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1475 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.034 | 0.002 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1475 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0745 | 0.3581 | 0.5976 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.034 | 0.002 | 0.5 |
Trypanosoma brucei | glucosidase, putative | 0.034 | 0.002 | 0.5 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.0785 | 0.3929 | 0.3917 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.0785 | 0.3929 | 0.3917 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.