Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.034 | 0.002 | 0.5 |
Giardia lamblia | Ceramide glucosyltransferase | 0.0338 | 0 | 0.5 |
Leishmania major | alpha glucosidase II subunit, putative | 0.034 | 0.002 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.1291 | 0.8384 | 1 |
Loa Loa (eye worm) | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.1475 | 1 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0743 | 0.3561 | 0.3548 |
Echinococcus multilocularis | bile acid beta glucosidase | 0.0785 | 0.3929 | 0.3917 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0785 | 0.3929 | 0.4674 |
Schistosoma mansoni | bile acid beta-glucosidase-related | 0.0785 | 0.3929 | 0.4674 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.034 | 0.002 | 0.5 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.4257 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0514 | 0.1546 | 0.4309 |
Loa Loa (eye worm) | hypothetical protein | 0.053 | 0.1687 | 0.167 |
Echinococcus multilocularis | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Echinococcus granulosus | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Brugia malayi | Ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.3568 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0743 | 0.3561 | 0.3548 |
Echinococcus multilocularis | non lysosomal glucosylceramidase | 0.0785 | 0.3929 | 0.3917 |
Trypanosoma brucei | glucosidase, putative | 0.034 | 0.002 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.034 | 0.002 | 0.5 |
Onchocerca volvulus | Ceramide glucosyltransferase homolog | 0.0745 | 0.3581 | 0.5976 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Echinococcus granulosus | non lysosomal glucosylceramidase | 0.0785 | 0.3929 | 0.3917 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Echinococcus granulosus | bile acid beta glucosidase | 0.0785 | 0.3929 | 0.3917 |
Schistosoma mansoni | ceramide glucosyltransferase | 0.0745 | 0.3581 | 0.4257 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0514 | 0.1546 | 0.4309 |
Schistosoma mansoni | alpha-glucosidase | 0.1291 | 0.8384 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.034 | 0.002 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1475 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.1475 | 1 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.034 | 0.002 | 0.5 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.1475 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0487 | 0.1315 | 0.3657 |
Onchocerca volvulus | 0.0919 | 0.5106 | 1 | |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0743 | 0.3561 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.